aminopropionitrile has been researched along with Lathyrism in 241 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Lathyrism: A paralytic condition of the legs caused by ingestion of lathyrogens, especially BETA-AMINOPROPIONITRILE or beta-N-oxalyl amino-L-alanine, which are found in the seeds of plants of the genus LATHYRUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "BAPN-induced osteolathyrism in young and older male rats was examined for its responses to parathormone-free, gel-filtered bovine parathyroid extract (extract P) and to glutaurine (gamma-L-glutamyl-taurine), the latter being a hitherto unknown putative hormone isolated from bovine parathyroid and reproduced by synthesis." | 7.66 | Effect of parathyroid extract and of glutaurine (gamma-L-glutamyl-taurine) on the manifestations of osteolathyrism. ( Bányai, B; Farkas, K; Feuer, L, 1980) |
| " Chronic administration of BAPN did not produce plasma lipid abnormalities such as those due to hyperlipidic diet." | 5.26 | Chronic lathyrism and atheromatosis in the rat. Protective effect of metformin. ( Bouissou, H; Douste-Blazy, L; Julian, M; Pieraggi, MT; Thiers, JC, 1980) |
| " The most advanced research involves prevention of the development of helical structure and transport of collagen by administration of proline analogues and controlled induction of lathyrism by administration of Beta-aminopropionitrile." | 4.75 | Pharmacological control of surgical scar tissue. ( Peacock, EE, 1978) |
| " Experimental lathyrism was induced by once daily subcutaneous administration of beta-aminopropionitrile (beta-APN), at a dose of 5 mg beta-APN/0." | 3.73 | Periodontal & systemic bone changes in rats with experimental lathyrism. ( Acikgoz, G; Basoglu, T; Cetinkaya, BO; Firatli, E; Keles, G; Yapici, O, 2006) |
| " In a separate test, DTC was also tested with copper sulfate to determine the importance of copper in DTC-induced osteolathyrism." | 3.70 | Analysis of the combined osteolathyritic effects of beta-aminopropionitrile and diethyldithiocarbamate on xenopus development. ( Cotter, MA; Dawson, DA; Pöch, G; Policz, DL, 2000) |
| "Since the lathyrogen beta-aminopropionitrile is known to affect the fibrogenic and physical properties of collagen polymers, we have examined its effects on collagenous components of methylcholanthrene-induced fibrosarcoma in rat." | 3.68 | Effect of lathyrogen on collagen of methylcholanthrene-induced sarcoma of rat. ( Bańkowski, E; Jodczyk, KJ; Sobolewski, K, 1990) |
| "The cause of the increased egg weight in hens with lathyrism was investigated by feeding laying birds with diets containing beta-aminopropionitrile, the toxic principle of certain legume seeds in the genus Lathyrus." | 3.67 | Lathyrism in laying hens and increases in egg weight. ( Chowdhury, SD; Davis, RH, 1988) |
| " Lathyrism was induced by feeding beta-aminopropionitrile fumarate for six weeks, and the lathyritic state was confirmed by characteristic radiographic, histomorphologic and biochemical findings." | 3.66 | Collagenase activity of cartilage in rats with experimental lathyrism: a model of bone diseases. ( Lubec, G; Plenk, H, 1980) |
| "BAPN-induced osteolathyrism in young and older male rats was examined for its responses to parathormone-free, gel-filtered bovine parathyroid extract (extract P) and to glutaurine (gamma-L-glutamyl-taurine), the latter being a hitherto unknown putative hormone isolated from bovine parathyroid and reproduced by synthesis." | 3.66 | Effect of parathyroid extract and of glutaurine (gamma-L-glutamyl-taurine) on the manifestations of osteolathyrism. ( Bányai, B; Farkas, K; Feuer, L, 1980) |
| " Ten patients with massive keloids, resistant to conventional therapy by excision, grafting, and/or intralesional injection of steroids, have been treated by excising the keloid, grafting the defect, inducing lathyrism with Beta aminopropionitrile fumurate or penicillamine and administering colchicine." | 3.66 | Pharmacologic control of surface scarring in human beings. ( Peacock, EE, 1981) |
| "Salamander and toad embryos will develop grossly observable tumors of the notochord if they are placed for 3 or more days in a solution of the lathyrism-producing chemicals beta-aminopropionitrile or aminoacetonitrile." | 3.64 | New method for the rapid determination of lathyrogenic agents. ( LEVY, BM, 1959) |
| "Konzo and lathyrism are associated with consumption of cassava and grass pea, respectively." | 2.47 | A new unifying hypothesis for lathyrism, konzo and tropical ataxic neuropathy: nitriles are the causative agents. ( Ambrosio, S; Boadas-Vaello, P; Cutillas, B; Llorens, J; Saldaña-Ruíz, S; Soler-Martín, C, 2011) |
| " A mouse model of lathyrism using subcutaneous injection of up to 500 mg/kg β-aminopropionitrile (BAPN) was developed and characterized (60 animals across 4 dosage groups)." | 1.42 | Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model. ( Gong, B; Kohn, DH; McNerny, EM; Morris, MD, 2015) |
| "Lathyrism is characterized by defective collagen synthesis due to inhibition of lysyl oxidase, an enzyme that is essential for interfibrillar collagen cross-linking." | 1.38 | Effect of defective collagen synthesis on epithelial implant interface: lathyritic model in dogs. An experimental preliminary study. ( Acikgoz, G; Cengiz, MI; Kirtiloğlu, T; Trisi, P; Wang, HL, 2012) |
| "However, in this rat animal model of lathyrism, the coupled alterations of tissue structural properties make it difficult to weigh the contribution of the anatomically confined material changes to the overall mechanical performance of whole bone." | 1.37 | Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral. ( Boskey, AL; Buchinger, B; Dall'Ara, E; Fratzl, P; Gamsjaeger, S; Klaushofer, K; Manjubala, I; Paschalis, EP; Phipps, R; Robins, S; Roschger, A; Roschger, P; Tatakis, DN; Varga, P; Zoehrer, R; Zysset, P, 2011) |
| "In the experimental group (18 rats), lathyrism was induced by a once daily subcutaneous administration of beta-APN for 40 days." | 1.36 | The effect of lathyrism on dentin structure of the rat incisors: a morphometric and scanning electron microscopic investigation. ( Bashir, MH; El Rouby, DH; Korany, NS, 2010) |
| "In the experimental group, lathyrism was induced by a once daily subcutaneous administration of beta-APN at a dose of 5mg in 0." | 1.35 | Ultrastructural and histomorphometric alterations of rat jaw bones after experimental induction of lathyrism. ( Bashir, MH; El Rouby, DH; Korany, NS, 2008) |
| " As experimental model we used lathyrism induced in mice by chronic administration of beta-amino-propionitril (beta-APN)." | 1.29 | [Effect of benzquercin on the connective tissue of lathyritic mice. Optic and electron microscopic study]. ( Azzi, G; Robert, AM; Safars, M; Viljanen-Tarifa, E; Vörös, E, 1995) |
| " A more consistent dependence on BAPN dosage was observed for the fraction of the demineralized bone matrix insoluble in 0." | 1.28 | BAPN dose dependence of mature crosslinking in bone matrix collagen of rabbit compact bone: corresponding variation of sonic velocity and equatorial diffraction spacing. ( Barnard, SM; Eyre, DR; Lees, S, 1990) |
| "Lathyrism has been reviewed in respect to four overlapping phases: finding an animal model for neurolathyrism, characterizing osteolathyrism in respect to its possible use as an animal model for human diseases, such as Marfan's syndrome, idiopathic juvenile scoliosis, etc." | 1.27 | Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism. ( Arunatut, O; Buranarugsa, MW; Yeager, VL, 1985) |
| "Experimental lathyrism was induced by feeding newborn chicks a diet containing 0." | 1.27 | Alterations of elastin fibrogenesis by inhibition of the formation of desmosine crosslinks. Comparison between the effect of beta-aminopropionitrile (beta-APN) and penicillamine. ( Contri, MB; Fornieri, C; Mori, G; Quaglino, D; Ronchetti, IP, 1985) |
| "The induction of centriacinar emphysema was attributed specifically to NO2 exposure." | 1.27 | Nitrogen-dioxide-induced emphysema in rats. Lack of worsening by beta-aminopropionitrile treatment. ( Blank, J; Burdette, L; Glasgow, JE; Pietra, GG; Weinbaum, G, 1988) |
| "The effect of chronic lathyrism on the mandible of the rat was studied." | 1.27 | Experimental lathyrism: exostoses and aneurysmal-like bone cysts of the mandible in the rat. ( Baden, E; Bouissou, H, 1987) |
| "Osteolathyrism is ascribed to an inhibition of crosslinking of the collagen by the lathyrogen and should be accompanied by a decrease in the elastic modulus of the bone." | 1.27 | The variation of sonic plesio-velocity in dose dependent lathyritic rabbit femurs. ( Barnard, SM; Churchill, D; Lees, S, 1987) |
| " Chronic administration of BAPN did not produce plasma lipid abnormalities such as those due to hyperlipidic diet." | 1.26 | Chronic lathyrism and atheromatosis in the rat. Protective effect of metformin. ( Bouissou, H; Douste-Blazy, L; Julian, M; Pieraggi, MT; Thiers, JC, 1980) |
| "These intracranial aneurysms have significant gross and microscopic similarities to human berry aneurysms." | 1.26 | Experimental intracranial aneurysms in rats. A gross and microscopic study. ( Popoff, N; Robertson, JT; Stadlan, EM; Suzuki, S; White, RP, 1980) |
| "Temporary chronic administration of Beta-amino-propionitrile (B." | 1.26 | Chronic lathyrism and atheromatosis in the rat. Study of the V.L.D.L. and plasma and arterial wall lipids. ( Bouissou, H; Douste-Blazy, L; Julian, M; Pieraggi, MT; Thiers, JC, 1978) |
| "The use of lathyric toxins (BAPN) in low dosage (1 g/kg/day) for a period of 8 weeks caused in the rat simultaneous changes in the skin and aortic connective tissues." | 1.26 | [Chronic lathyrism. Protective effect of pyridinol carbamate on connective tissue lesions in the rat (author's transl)]. ( Bouissou, H; Foulquier, F; Julian, M; Pieraggi, MT; Vila, C, 1977) |
| "Growth of a plasma cell myeloma (Adj PC-5) was studied in mice made lathyritic by the administration of beta-amino-proprionitrile (BAPN)." | 1.25 | Growth of a plasma cell myeloma in lathyritic mice. ( Martino, LJ; Taylor, JJ; Yeager, VL, 1975) |
| "beta-Aminopropionitrile treatment also decreased the amount of N-acetylhexosamines in the chick embryo and decreased the percentage of the hexosamine esterified by nucleotides." | 1.25 | Alterations in glycosaminoglycan metabolism in beta-aminopropionitrile-treated chick embryos. ( Elders, MJ; Hughes, ER; Smith, JD; Smith, WG, 1973) |
| "Experimentally induced lathyrism was employed to enhance collagen solubility, and vitamin D deficiency to allow accumulation of osteoid, the precursor of bone matrix." | 1.25 | Collagen heterogeneity within different growth regions of long bones of rachitic and non-rachitic chicks. ( Gross, J; Kang, AH; Toole, BP; Trelstad, RL, 1972) |
| "Neurolathyrism in man may be caused by beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, a neurotoxin recently identified in Lathyrus sativus seeds." | 1.24 | Naturally occurring toxic factors in plants and animals used as food. ( Strong, FM, 1966) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 216 (89.63) | 18.7374 |
| 1990's | 13 (5.39) | 18.2507 |
| 2000's | 7 (2.90) | 29.6817 |
| 2010's | 5 (2.07) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McNerny, EM | 1 |
| Gong, B | 1 |
| Morris, MD | 1 |
| Kohn, DH | 1 |
| El Rouby, DH | 2 |
| Bashir, MH | 2 |
| Korany, NS | 2 |
| Llorens, J | 1 |
| Soler-Martín, C | 1 |
| Saldaña-Ruíz, S | 1 |
| Cutillas, B | 1 |
| Ambrosio, S | 1 |
| Boadas-Vaello, P | 1 |
| Cengiz, MI | 1 |
| Kirtiloğlu, T | 1 |
| Acikgoz, G | 2 |
| Trisi, P | 1 |
| Wang, HL | 2 |
| Paschalis, EP | 1 |
| Tatakis, DN | 1 |
| Robins, S | 1 |
| Fratzl, P | 1 |
| Manjubala, I | 1 |
| Zoehrer, R | 1 |
| Gamsjaeger, S | 1 |
| Buchinger, B | 1 |
| Roschger, A | 1 |
| Phipps, R | 1 |
| Boskey, AL | 1 |
| Dall'Ara, E | 1 |
| Varga, P | 1 |
| Zysset, P | 1 |
| Klaushofer, K | 1 |
| Roschger, P | 1 |
| Dawson, DA | 4 |
| Rinaldi, AC | 1 |
| Pöch, G | 4 |
| Kundel, HL | 1 |
| DASLER, W | 4 |
| MILLISER, RV | 2 |
| LALICH, JJ | 10 |
| LEVY, BM | 1 |
| WIRKA, HW | 1 |
| ANGEVINE, CD | 1 |
| LEVENE, CI | 8 |
| VAN DEN HOOFF, A | 1 |
| GROSS, J | 8 |
| GOERTTLER, K | 1 |
| HARTMANN, F | 3 |
| ORLOFF, SD | 1 |
| SALMI, A | 1 |
| KULONEN, E | 3 |
| BURZYNSKI, NJ | 1 |
| TAKEOKA, O | 1 |
| ANGEVINE, DM | 3 |
| HAUSMANN, E | 1 |
| NORTON, TB | 3 |
| HORWITZ, SF | 1 |
| GRIES, G | 1 |
| LINDNER, J | 1 |
| AKAMATSU, Y | 1 |
| TAKASHASHI, M | 1 |
| BICKLEY, HC | 1 |
| ORBISON, JL | 5 |
| TANZER, ML | 2 |
| JOHN, DW | 1 |
| SOKOL, RJ | 1 |
| HUNT, RD | 1 |
| KUEHN, K | 1 |
| IWANGOFF, P | 1 |
| DURRUTI, M | 1 |
| HAMMERSTEIN, F | 1 |
| STECHER, K | 1 |
| HOLZMANN, H | 2 |
| KORTING, GW | 2 |
| MARTINESI, L | 2 |
| ALBERTINI, E | 2 |
| GORI, A | 2 |
| YEAGER, VL | 5 |
| PICCHIONI, JA | 1 |
| SETHER, LA | 1 |
| SEVERSON, AR | 2 |
| SMITH, DW | 1 |
| WIRTSCHAFTER, ZT | 1 |
| BENTLEY, JP | 2 |
| ROSMUS, F | 1 |
| DEYL, Z | 2 |
| TRNAVSKY, K | 3 |
| TRNAVSKA, Z | 3 |
| BALL, RA | 1 |
| SAUTTER, JH | 1 |
| POMEROY, BS | 1 |
| WAIBEL, PE | 1 |
| MCCALLUM, HM | 2 |
| OLLERICH, D | 1 |
| CARLTON, WW | 1 |
| PRAUS, R | 1 |
| BRETTSCHNEIDER, I | 1 |
| HVEZDOVA, H | 1 |
| STERBOVA, V | 1 |
| BACHHUBER, TE | 1 |
| SCHILLING, ED | 1 |
| STRONG, FM | 2 |
| KEECH, MK | 1 |
| JUVA, K | 1 |
| Keles, G | 1 |
| Basoglu, T | 1 |
| Yapici, O | 1 |
| Cetinkaya, BO | 1 |
| Firatli, E | 1 |
| Ponseti, IV | 1 |
| Khogali, A | 1 |
| Turner, H | 1 |
| Kohn, RR | 1 |
| Leash, AM | 1 |
| Maurel, E | 3 |
| Shuttleworth, CA | 3 |
| Bouissou, H | 22 |
| Lubec, G | 1 |
| Plenk, H | 2 |
| Pasquali-Ronchetti, I | 2 |
| Bressan, GM | 2 |
| Fornieri, C | 3 |
| Baccarani-Contri, M | 1 |
| Castellani, I | 2 |
| Volpin, D | 2 |
| Feuer, L | 1 |
| Bányai, B | 1 |
| Farkas, K | 1 |
| Dayan, D | 1 |
| Shoshan, S | 2 |
| Baden, E | 2 |
| Pieraggi, MT | 16 |
| Julian, M | 18 |
| de Graeve, J | 3 |
| Thiers, JC | 5 |
| Miller, EJ | 5 |
| Rhodes, RK | 1 |
| Rich, CB | 1 |
| Foster, JA | 2 |
| Streifler, M | 1 |
| Cohn, DF | 1 |
| Peacock, EE | 13 |
| Adam, M | 1 |
| Macek, K | 1 |
| Douste-Blazy, L | 3 |
| Suzuki, S | 1 |
| Robertson, JT | 1 |
| White, RP | 1 |
| Stadlan, EM | 1 |
| Popoff, N | 1 |
| Di Cesare, PE | 1 |
| Nimni, ME | 4 |
| Yazdi, M | 1 |
| Cheung, DT | 1 |
| Taverne, AA | 2 |
| Dombi, GW | 1 |
| Haut, RC | 2 |
| Sullivan, WG | 1 |
| Azzi, G | 1 |
| Safars, M | 1 |
| Viljanen-Tarifa, E | 1 |
| Vörös, E | 1 |
| Robert, AM | 1 |
| Haque, A | 1 |
| Hossain, M | 1 |
| Lambein, F | 2 |
| Bell, EA | 1 |
| Dahl, T | 1 |
| Sabsay, B | 1 |
| Veis, A | 1 |
| Mentzer, RK | 1 |
| Smith, ND | 1 |
| Cotter, MA | 2 |
| Policz, DL | 2 |
| Stoffer, DA | 1 |
| Nichols, JP | 1 |
| Arem, AJ | 1 |
| Misiorowski, R | 1 |
| Mecham, R | 1 |
| Imberman, M | 1 |
| Faris, B | 1 |
| Franzblau, C | 1 |
| Kern, M | 1 |
| Módis, L | 1 |
| Antal, M | 1 |
| Földes, I | 1 |
| Cohen, IK | 1 |
| Moncure, CW | 1 |
| Witorsch, RJ | 1 |
| Diegelmann, RF | 1 |
| Van Caneghem, P | 1 |
| Lapiere, CM | 1 |
| Rosenthall, L | 1 |
| Kaye, M | 1 |
| Nawrot, CF | 2 |
| Campbell, DJ | 1 |
| Peyron, JG | 1 |
| Foulquier, F | 1 |
| Vila, C | 1 |
| Gibson, KD | 1 |
| Segen, BJ | 1 |
| Doller, HJ | 1 |
| Reddi, AH | 1 |
| Sullivan, NE | 1 |
| Gabler, W | 2 |
| Brachmann, J | 1 |
| Dörfler, HP | 1 |
| Schmidt, W | 1 |
| Asatoor, AM | 1 |
| Bending, MR | 1 |
| Milne, MD | 1 |
| Maruyama, K | 1 |
| Shimada, Y | 1 |
| Aumailley, M | 1 |
| Drouillet, F | 1 |
| Bricaud, H | 1 |
| Butler, C | 1 |
| Madden, JW | 6 |
| Davis, WM | 3 |
| McClain, PE | 1 |
| Dousset, JC | 1 |
| Soula, G | 1 |
| Friedrich, L | 1 |
| Wuppermann, D | 1 |
| Zimmermann, F | 1 |
| Speer, DP | 2 |
| Chvapil, M | 2 |
| Martino, LJ | 1 |
| Taylor, JJ | 2 |
| Aleo, JJ | 4 |
| Dirksen, TR | 1 |
| Nakashima, Y | 1 |
| Sueishi, K | 1 |
| Yamaguchi, S | 1 |
| Seidler, E | 1 |
| Wendler, D | 1 |
| van Doorn, K | 1 |
| de Man, B | 1 |
| Hendriks, T | 1 |
| Lees, S | 2 |
| Eyre, DR | 2 |
| Barnard, SM | 2 |
| Bańkowski, E | 2 |
| Sobolewski, K | 1 |
| Jodczyk, KJ | 1 |
| Buranarugsa, MW | 1 |
| Arunatut, O | 1 |
| Chowdhury, SD | 2 |
| Davis, RH | 2 |
| Tinker, D | 1 |
| Rucker, RB | 1 |
| Ronchetti, IP | 2 |
| Contri, MB | 2 |
| Quaglino, D | 1 |
| Mori, G | 1 |
| Fornieri, CC | 1 |
| Durandeau, C | 1 |
| Gendre, PM | 1 |
| Aumonier, P | 1 |
| Blank, J | 1 |
| Glasgow, JE | 1 |
| Pietra, GG | 1 |
| Burdette, L | 1 |
| Weinbaum, G | 1 |
| Lemmens, IG | 1 |
| Tonino, GJ | 1 |
| Churchill, D | 1 |
| Terpin, T | 1 |
| Roach, MR | 1 |
| Koski, K | 1 |
| Rönning, O | 1 |
| Nakamura, T | 1 |
| Dabrowski, R | 1 |
| Szczepanowska, A | 1 |
| Hosoda, Y | 2 |
| Suzuki, M | 2 |
| King, CT | 1 |
| Horigan, E | 1 |
| Wilk, AL | 1 |
| Bar, A | 1 |
| Hurwitz, S | 1 |
| Pinon, JF | 1 |
| Neuzil, E | 1 |
| Kranzler, J | 1 |
| Franco-Browder, S | 1 |
| Manley, G | 1 |
| Coulson, WF | 1 |
| Linker, A | 1 |
| Bottcher, E | 1 |
| Orlowski, WA | 1 |
| Orbison, LJ | 1 |
| McCrary, C | 1 |
| Bihari-Varga, M | 1 |
| Biró, T | 1 |
| Lévai, J | 1 |
| Bates, CJ | 1 |
| Bailey, AJ | 3 |
| Elders, MJ | 1 |
| Smith, JD | 1 |
| Smith, WG | 1 |
| Hughes, ER | 1 |
| Lane, JM | 1 |
| Parkes, LJ | 1 |
| Prockop, DJ | 1 |
| Bradley, KH | 1 |
| McConnell, SD | 1 |
| Crystal, RG | 1 |
| Harris, ED | 1 |
| O'Dell, BL | 2 |
| Bettelheim, FA | 1 |
| Wang, TJ | 1 |
| Van Rompuy, L | 1 |
| Van Parijs, R | 1 |
| Ressler, C | 1 |
| Orloff, S | 2 |
| Hanumantha Rao, V | 2 |
| Bose, SM | 5 |
| Barrow, MV | 3 |
| Simpson, CF | 2 |
| Rao, VH | 3 |
| Toole, BP | 2 |
| Kang, AH | 4 |
| Trelstad, RL | 3 |
| Sykes, BC | 1 |
| Partridge, SM | 1 |
| Mándi, B | 1 |
| Hadházy, C | 1 |
| Soltész, K | 1 |
| Balázs, G | 1 |
| Nanda, V | 1 |
| Nanda, R | 1 |
| Anna, K | 1 |
| Harry, J | 1 |
| Wicks, MP | 1 |
| Gardner, DL | 1 |
| Conner, WT | 1 |
| Scheinman, JI | 1 |
| Brown, DM | 1 |
| Vernier, RL | 1 |
| Michael, AF | 1 |
| Brendel, K | 1 |
| Pinto, JS | 1 |
| Carmichael, DJ | 1 |
| Dodd, CM | 1 |
| Ledvina, M | 1 |
| Leonard, JR | 1 |
| Fowler, LJ | 2 |
| Peach, CM | 1 |
| Fabre, MT | 1 |
| Pieraggi-Fabre, MT | 1 |
| O'Neal, RM | 1 |
| Gardner, AF | 1 |
| Rao, SL | 2 |
| Malathi, K | 1 |
| Sarma, PS | 2 |
| Paik, WC | 2 |
| Allen, JR | 1 |
| Mani, KS | 1 |
| Sriramachari, S | 1 |
| Page, RC | 2 |
| Benditt, EP | 2 |
| Obrink, B | 1 |
| Willis, LS | 1 |
| Müller, PK | 1 |
| McGoodwin, E | 1 |
| Martin, GR | 4 |
| Cammarata, A | 1 |
| Golub, L | 3 |
| Stern, B | 2 |
| Glimcher, M | 3 |
| Goldhaber, P | 2 |
| Niewiarowski, S | 2 |
| Worowski, K | 2 |
| Jacques, J | 1 |
| Ishikawa, H | 1 |
| Mori, Y | 1 |
| Niinobe, S | 1 |
| Craven, JL | 1 |
| Mennin, S | 1 |
| Thomas, DW | 1 |
| Smith, RF | 1 |
| Ellen, RP | 1 |
| Siegel, RC | 1 |
| McCoy, FD | 1 |
| Igarashi, S | 1 |
| Stivers, FE | 2 |
| Steffer, AJ | 1 |
| Yarington, CT | 2 |
| Steffek, AJ | 1 |
| Deshmukh, K | 2 |
| Butler, WT | 1 |
| Piez, KA | 3 |
| Bornstein, P | 1 |
| Christian, GL | 1 |
| Hume, M | 1 |
| Hukill, PB | 1 |
| Balis, JU | 1 |
| Chan, AS | 1 |
| Conen, PE | 1 |
| Finkelstein, S | 1 |
| Pinnell, SR | 1 |
| Kühn, K | 1 |
| Shimizu, M | 1 |
| Taguchi, S | 1 |
| Ba0nkowski, E | 1 |
| Hanson, H | 1 |
| Wiederanders, B | 1 |
| Mecca, CE | 1 |
| Savage, JE | 1 |
| Bird, DW | 1 |
| Reynolds, G | 1 |
| Morsches, B | 1 |
| Herd, K | 1 |
| Rojkind, M | 1 |
| Júarez, H | 1 |
11 reviews available for aminopropionitrile and Lathyrism
| Article | Year |
|---|---|
A new unifying hypothesis for lathyrism, konzo and tropical ataxic neuropathy: nitriles are the causative agents.
Topics: Aminopropionitrile; Animals; Brain; Cyanides; Humans; Lathyrism; Lathyrus; Manihot; Molecular Struct | 2011 |
Pharmacological control of surgical scar tissue.
Topics: Aminopropionitrile; Animals; Cicatrix; Colchicine; Collagen; Connective Tissue; Humans; Lathyrism; P | 1978 |
Role of selected nutrients in synthesis, accumulation, and chemical modification of connective tissue proteins.
Topics: Aminopropionitrile; Animals; Ascorbic Acid; Collagen; Connective Tissue; Copper; Cross-Linking Reage | 1985 |
Possibilities for the therapeutic control of fibrosis.
Topics: Aldehydes; Aminopropionitrile; Animals; Bone Diseases; Chick Embryo; Collagen; Connective Tissue Dis | 1985 |
Periosteal control of mandibular condyle growth.
Topics: Aminopropionitrile; Animals; Biomechanical Phenomena; Lathyrism; Mandibular Condyle; Mitosis; Perios | 1985 |
Biology of wound repair.
Topics: Aminopropionitrile; Cicatrix; Collagen; Connective Tissue; Dactinomycin; Epithelium; Fibroblasts; Hu | 1973 |
Biologic frontiers in the control of healing. Thomas G. Orr Memorial Lecture.
Topics: Aminopropionitrile; Animals; Clinical Trials as Topic; Collagen; Contracture; Drug Hypersensitivity; | 1973 |
Lathyrism: a review.
Topics: Abnormalities, Drug-Induced; Amino Acid Oxidoreductases; Aminopropionitrile; Aneurysm; Animals; Aort | 1974 |
[Oblique bindings in elastin and their developmental changes].
Topics: Age Factors; Aminopropionitrile; Animals; Arteriosclerosis; Chemical Phenomena; Chemistry, Physical; | 1968 |
The unsolved mysteries of lathyrism.
Topics: Aminopropionitrile; Animals; Collagen; Culture Techniques; Glutamate Dehydrogenase; Glutamine; Human | 1970 |
Lathyrism.
Topics: Acidosis; Aminopropionitrile; Animals; Blood-Brain Barrier; Bone Diseases; Chickens; Collagen; Colla | 1969 |
2 trials available for aminopropionitrile and Lathyrism
| Article | Year |
|---|---|
Biologic frontiers in the control of healing. Thomas G. Orr Memorial Lecture.
Topics: Aminopropionitrile; Animals; Clinical Trials as Topic; Collagen; Contracture; Drug Hypersensitivity; | 1973 |
The secondary healing phenomenon during lathyrism.
Topics: Aminopropionitrile; Animals; Clinical Trials as Topic; Collagen; Lathyrism; Rats; Surgical Wound Deh | 1968 |
229 other studies available for aminopropionitrile and Lathyrism
| Article | Year |
|---|---|
Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model.
Topics: 3T3 Cells; Aminopropionitrile; Animals; Biomechanical Phenomena; Collagen; Disease Models, Animal; F | 2015 |
Ultrastructural and histomorphometric alterations of rat jaw bones after experimental induction of lathyrism.
Topics: Alveolar Process; Aminopropionitrile; Animals; Cell Count; Disease Models, Animal; Image Processing, | 2008 |
The effect of lathyrism on dentin structure of the rat incisors: a morphometric and scanning electron microscopic investigation.
Topics: Aminopropionitrile; Animals; Collagen; Dentin; Dentin Dysplasia; Dentinogenesis; Injections, Subcuta | 2010 |
Effect of defective collagen synthesis on epithelial implant interface: lathyritic model in dogs. An experimental preliminary study.
Topics: Aminopropionitrile; Animals; Bone Density; Bone Remodeling; Collagen; Connective Tissue; Dental Impl | 2012 |
Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral.
Topics: Aminopropionitrile; Analysis of Variance; Animals; Biomechanical Phenomena; Bone Density; Collagen; | 2011 |
Biochemical and toxicological evaluation of agent-cofactor reactivity as a mechanism of action for osteolathyrism.
Topics: Abnormalities, Drug-Induced; Aminoacetonitrile; Aminopropionitrile; Animals; Bone Diseases; Collagen | 2002 |
Osteolathyrism in the rat: an X-ray diffraction study of collagen from normal and lathyritic rats. 1964.
Topics: Aminopropionitrile; Animals; Collagen; Connective Tissue Diseases; History, 20th Century; Lathyrism; | 2002 |
Experimental lathyrism in mice fed diets containing sweet peas or beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Diet; Lathyrism; Lathyrus; Mice; Pisum sativum | 1957 |
Role of cyanoacetic acid in production of lathyrism in rats by beta-aminopropionitrile.
Topics: Acetates; Aminopropionitrile; Animals; Cyanides; Lathyrism; Rats | 1958 |
New method for the rapid determination of lathyrogenic agents.
Topics: Aminopropionitrile; Humans; Lathyrism | 1959 |
Influence of beta-aminopropionitrile feeding on collagen synthesis in rat aortas.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Collagen; Cyanates; Lathyrism; Rats | 1961 |
The lathyrogenic effect of isonicotinic acid hydrazide (INAH) on the chick embryo and its reversal by pyridoxal.
Topics: Aminopropionitrile; Animals; Bone and Bones; Chick Embryo; Collagen; Embryo, Mammalian; Embryo, Nonm | 1961 |
Morphologic evidence for collagen changes in chick embryos treated with beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Chick Embryo; Collagen; Cyanides; Extracellular Matrix; Lathyrism; Skin | 1959 |
[Histopathological findings in chick embryos after application of beta-aminopropionitrile (BAPN; Lathyrus factor].
Topics: Aminopropionitrile; Animals; Chick Embryo; Cyanides; Lathyrism; Lathyrus | 1961 |
Experimental lathyrism in the chick embryo. The distribution of beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Bone and Bones; Chick Embryo; Collagen; Cyanides; Lathyrism; Proteins | 1963 |
Inhibited incorporation of ammonium chloride labelled with nitrogen-15 in chick embryos treated with beta-aminopropionitrile.
Topics: Aminopropionitrile; Ammonium Chloride; Animals; Chick Embryo; Cyanides; Lathyrism; Nitrogen | 1962 |
EFFECT OF BETA-AMINOPROPIONITRILE ON CULTURED CELLS.
Topics: Aminopropionitrile; Antimetabolites; Cell Line; Cyanides; Fibroma; Fumarates; Gingiva; Hexoses; Hist | 1963 |
PROLIFERATION OF MAST CELLS IN THE BONE MARROW OF RATS AFTER FEEDING BETA-AMINOPROPIONITRILE AND BETA-MERCAPTOETHYLAMINE.
Topics: Aminopropionitrile; Bone Marrow; Cyanides; Cysteamine; Lathyrism; Mast Cells; Mercaptoethylamines; R | 1963 |
THE FORMATION AND DISSOLUTION OF GELS FROM COLLAGEN SOLUTIONS: THE EFFECT OF BETA-AMINOPROPIONITRILE.
Topics: Aminopropionitrile; Antimetabolites; Collagen; Colorimetry; Cyanides; Gels; Lathyrism; Rats; Researc | 1963 |
THE EFFECT OF BETA-AMINOPROPIONITRILE (BAPN) ON BACTERIA.
Topics: Aminopropionitrile; Bacteria; Culture; Cyanides; Enterococcus faecalis; Escherichia coli; Glycosamin | 1963 |
[COMPARATIVE STUDIES ON THE COLLAGEN BREAKDOWN IN INFLAMED AND LATHYRITICALLY CHANGED TISSUES].
Topics: Aminopropionitrile; Collagen; Cyanides; Hydroxyproline; Inflammation; Lathyrism; Rats; Research; Ten | 1963 |
LATHYRISM OF MICE; BONY CHANGES INDUCED BY BETA-AMINOPROPIONITRILE FEEDING AND AUTORADIOGRAPHIC STUDY OF BONES USING S35.
Topics: Aminopropionitrile; Aortic Aneurysm; Autoradiography; Bone and Bones; Cyanides; Exostoses; Kyphosis; | 1964 |
THE EFFECT OF A LATHYROGEN ON SULFATE METABOLISM IN CULTURES OF THE STRAIN L FIBROBLAST.
Topics: Aminopropionitrile; Connective Tissue; Cyanides; Electrophoresis; Fibroblasts; Lathyrism; Metabolism | 1964 |
COLLAGEN METABOLISM IN THE NORMAL AND LATHYRITIC CHICK.
Topics: Amino Acids; Aminopropionitrile; Animals; Anti-Bacterial Agents; Carbon Isotopes; Chick Embryo; Chro | 1964 |
INFLUENCE OF BETA-AMINOPROPIONITRILE (BAPN) ON SOME ASPECTS OF SULFATE METABOLISM BY THE ISOLATED PERFUSED RAT LIVER.
Topics: Aminopropionitrile; Cyanides; Lathyrism; Liver; Metabolism; Perfusion; Pharmacology; Rats; Research; | 1964 |
[ENCHONDRAL MINERALIZATION DISORDERS IN EXPERIMENTAL LATHYRISM].
Topics: Aminopropionitrile; Animals; Bone and Bones; Bone Diseases; Cartilage; Collagen; Cyanides; Glycosami | 1963 |
EXPERIMENTAL LATHYRISM. AN AUTORADIOGRAPHIC STUDY.
Topics: Aminopropionitrile; Animals; Autoradiography; Bone and Bones; Bone Development; Carbon Isotopes; Chi | 1964 |
[STUDIES ON THE METABOLISM OF COLLAGEN. I. THE INCORPORATION OF C14-GLYCINE INTO THE COLLAGEN OF LATHYRITIC RATS].
Topics: Amino Acids; Aminopropionitrile; Collagen; Glycine; Lathyrism; Metabolism; Pharmacology; Proteins; R | 1964 |
[EXPERIMENTAL ANALYSIS OF ARTERIOPATHIC PATHOGENETIC PERIODS IN CHEMICALLY INDUCED LATHYROID SYNDROMES].
Topics: Aminopropionitrile; Aortic Aneurysm; Blood Vessels; Cyanides; Elastic Tissue; Lathyrism; Mice; Muscl | 1964 |
LATHYRISM IN DIABETIC RATS.
Topics: Aminopropionitrile; Animals; Carbohydrate Metabolism; Cyanides; Diabetes Mellitus, Experimental; Exo | 1965 |
EFFECT OF TWO LATHYROGENS ON CYTOCHROME OXIDASE IN CULTURES OF THE STRAIN L FIBROBLAST.
Topics: Aminopropionitrile; Animals; Cyanides; Electron Transport Complex IV; Enzyme Repression; Fibroblasts | 1964 |
OSTEOLATHYRISM IN THE HAMSTER: PATHOLOGICAL AND CHEMICAL CHANGES PRODUCED BY BETA-AMINOPROPIONITRILE IN CONNECTIVE TISSUES.
Topics: Aminopropionitrile; Bone Diseases; Collagen; Connective Tissue; Cricetinae; Cyanides; Hydroxyproline | 1965 |
LATHYRISM.
Topics: Aminopropionitrile; Cyanides; Diet; Lathyrism; Metabolism; Toxicology | 1964 |
EXTRACTABLE COLLAGEN IN THE NORMAL AND ANEURYSMAL AORTA: STUDIES IN LATHYRISM.
Topics: Aminopropionitrile; Aorta; Aortic Aneurysm; Chemical Phenomena; Chemistry; Collagen; Cyanides; Elast | 1965 |
[EXPERIMENTAL LATHYRISM].
Topics: Aminopropionitrile; Animals; Chick Embryo; Collagen; Dogs; Lathyrism; Meat; Physiology; Poultry; Rat | 1965 |
[CRITICAL ANALYSIS ON THE VALUE OF BIOCHEMICAL ALOLOGIC MOMENTS IN PATHOGENESIS OF EXPERIMENTAL OSTEOLATHYRISM].
Topics: Aminopropionitrile; Animals; Biochemical Phenomena; Biochemistry; Cyanides; Lathyrism; Mice; Rats; R | 1964 |
NATURAL AND EXPERIMENTAL DISSECTING ANEURYSMS IN TURKEYS.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm; Aortic Dissection; Aortic Rupture; Bone and Bones; Car | 1965 |
EXPERIMENTAL LATHYRISM IN MICE.
Topics: Aminopropionitrile; Aortic Aneurysm; Aortic Rupture; Chemical Phenomena; Chemistry; Elastic Tissue; | 1965 |
EXPERIMENTAL LATHYRISM IN TISSUE CULTURE.
Topics: Aminopropionitrile; Chick Embryo; Elastic Tissue; Lathyrism; Mercaptoethylamines; Mice; Pharmacology | 1965 |
H3-THYMIDINE LABELED CELLS IN RAT PERIOSTEUM: AUTORADIOGRAPHIC STUDY OF DISTRIBUTION IN NORMAL AND LATHYRIC RATS.
Topics: Aminopropionitrile; Autoradiography; Cyanides; Exostoses; Lathyrism; Metabolism; Pathology; Perioste | 1965 |
BETA-AMINOPROPIONITRILE TOXICITY IN THE WHITE PEKIN DUCK.
Topics: Aminopropionitrile; Animals; Bone Diseases; Cyanides; Ducks; Lathyrism; Meat; Pathology; Poultry; Re | 1965 |
[THE EFFECT OF LATHYROGENS ON THE CORNEA. THE EFFECT OF BETA-AMINOPROPIONITRILE ON THE SULFATION OF ACID MUCOPOLYSACCHARIDES OF THE BEEF CORNEA IN VITRO].
Topics: Aminopropionitrile; Animals; Cattle; Cornea; Cyanides; Glycosaminoglycans; In Vitro Techniques; Lath | 1965 |
Lathyrus factor activity of beta-aminopropionitrile and related compounds.
Topics: Aminopropionitrile; Cyanides; Lathyrism; Lathyrus | 1955 |
Electron microscope study of the lathyritic rat aorta.
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm; Collagen; Connective Tissue; E | 1960 |
Beta aminopropionitrile concentration and angiorrhexis in rats.
Topics: Aminopropionitrile; Animals; Blood Vessels; Cyanides; Disease; Lathyrism; Rats; Vascular Diseases | 1960 |
Alterations in state of molecular aggregation of collagen induced in chick embryos by beta-aminopropionitrile (lathyrus factor).
Topics: Aminopropionitrile; Animals; Bone and Bones; Chick Embryo; Collagen; Cyanides; Lathyrism; Lathyrus; | 1959 |
alpha-Keto acids in beta-aminopropionitrile intoxication (lathyrism).
Topics: Aminopropionitrile; Cyanides; Keto Acids; Lathyrism | 1961 |
Periodontal & systemic bone changes in rats with experimental lathyrism.
Topics: Alveolar Process; Aminopropionitrile; Animals; Bone and Bones; Bone Density; Bone Resorption; Lathyr | 2006 |
50 years ago in CORR : skeletal lesions produced by aminonitriles by Ignacio V. Ponseti MD CORR 1957;9:131-144.
Topics: Aminopropionitrile; Animals; Bone and Bones; History, 20th Century; Lathyrism; Lathyrus; Radiography | 2008 |
Excretion of thiocyanate in osteolathyrism.
Topics: Aminopropionitrile; Animals; Lathyrism; Nitriles; Rats; Thiocyanates | 1967 |
Dilatation of colon induced in rats by beta-aminopropionitrile feeding.
Topics: Aminopropionitrile; Animals; Animals, Newborn; Aortic Rupture; Colonic Diseases; Cottonseed Oil; Cya | 1967 |
Long-term lathyrogen administration to rats, with special reference to aging.
Topics: Aging; Aminopropionitrile; Animals; Body Weight; Female; Growth; Lathyrism; Longevity; Male; Nitrile | 1967 |
Lathyrism: aortic and cutaneous collagen in the rat.
Topics: Aminopropionitrile; Animals; Aorta; Collagen; Lathyrism; Male; Rats; Rats, Inbred Strains; Skin; Sol | 1982 |
Collagenase activity of cartilage in rats with experimental lathyrism: a model of bone diseases.
Topics: Aminopropionitrile; Animals; Cartilage, Articular; Female; Lathyrism; Microbial Collagenase; Rats; S | 1980 |
[Lathyrism and collagens I and III (author's transl)].
Topics: Aging; Aminopropionitrile; Animals; Collagen; Connective Tissue; Fibroblasts; Humans; Lathyrism; Mal | 1982 |
Elastin fiber-associated glycosaminoglycans in beta-aminopropionitrile-induced lathyrism.
Topics: Aminopropionitrile; Animals; Aorta; Chickens; Chondroitinases and Chondroitin Lyases; Collagen; Derm | 1984 |
Effect of parathyroid extract and of glutaurine (gamma-L-glutamyl-taurine) on the manifestations of osteolathyrism.
Topics: Aminopropionitrile; Animals; Bone and Bones; Calcium; Cartilage; Cattle; Chondroitin Sulfates; Gluta | 1980 |
The response of periodontal ligament and mandibular joint to the collagen-crosslink inhibitor penicillamine in the rat.
Topics: Aminopropionitrile; Animals; Collagen; Lathyrism; Penicillamine; Periodontal Ligament; Rats; Temporo | 1981 |
The effect of beta-aminoproprionitrile on the lingual artery and aorta of the rat: a light microscopic study.
Topics: Aminopropionitrile; Animals; Aorta; Arteries; Lathyrism; Male; Rats; Rats, Inbred Strains; Time Fact | 1982 |
Chronic lathyrism. Plasma, aorta and rat skin treated for five months with beta-aminopropionitrile with or without high fat diet.
Topics: Aminopropionitrile; Animals; Aorta; Blood Vessels; Cholesterol; Chronic Disease; Dietary Fats; Lathy | 1980 |
[Lathyrism and collagens I and III (author's transl)].
Topics: Aminopropionitrile; Animals; Collagen; Connective Tissue; Electrophoresis, Polyacrylamide Gel; Lathy | 1982 |
Preparation and characterization of the different types of collagen.
Topics: Aminopropionitrile; Animals; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Collagen; | 1982 |
Isolation of soluble elastin-lathyrism.
Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Cartilage; Chickens; Elastin; Lathyrism; Lung; Meth | 1982 |
[New findings in chronic Lathyrus sativus toxicity].
Topics: Adolescent; Adult; Aminopropionitrile; Bone and Bones; Humans; Lathyrism | 1982 |
Pharmacologic control of surface scarring in human beings.
Topics: Adolescent; Adult; Aged; Aminopropionitrile; Child; Cicatrix; Colchicine; Drug Administration Schedu | 1981 |
Alterations of the connective tissue components induced by beta-aminopropionitrile.
Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chickens; Collagen; Connective Tissue; Elastin; Ext | 1981 |
3-Hydroxypyridinium cross-links in lathyritic tissues.
Topics: Amino Acids; Aminopropionitrile; Animals; Chemical Phenomena; Chemistry; Collagen; Elastin; Hydrazin | 1981 |
Chronic lathyrism and atheromatosis in the rat. Protective effect of metformin.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Lath | 1980 |
Experimental intracranial aneurysms in rats. A gross and microscopic study.
Topics: Aminopropionitrile; Animals; Carotid Arteries; Cerebral Arteries; Desoxycorticosterone; Disease Mode | 1980 |
[Effect of pyridinol carbamate on long-term lathyrism and experimental atheroma in the rat. Histological and biochemical study].
Topics: Aminopropionitrile; Animals; Arteriosclerosis; Carbamates; Cholesterol; Diet, Atherogenic; Lathyrism | 1980 |
Long term lathyrism and atherogenic diet in the rat. Protective action of pyridinol carbamate.
Topics: Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Carbamates; Cholesterol; Diet, Atherogenic; La | 1980 |
Effects of lathyritic drugs and lathyritic demineralized bone matrix on induced and sustained osteogenesis.
Topics: Aminopropionitrile; Animals; Bone Density; Bone Matrix; Lathyrism; Osteogenesis; Rats; Rats, Inbred | 1994 |
Collagen responsible for tooth eruption? A study of the eruption of rat incisors.
Topics: Aminoacetonitrile; Aminopropionitrile; Animals; Body Weight; Collagen; Female; Lathyrism; Penicillam | 1993 |
Correlation of high-speed tensile strength with collagen content in control and lathyritic rat skin.
Topics: Aminopropionitrile; Animals; Collagen; Diet; Hydroxyproline; Lathyrism; Rats; Skin; Solubility; Tens | 1993 |
[Effect of benzquercin on the connective tissue of lathyritic mice. Optic and electron microscopic study].
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Capillary Permeability; Collagen; Connective Tissue; D | 1995 |
Evidence of osteolathyrism among patients suffering from neurolathyrism in Bangladesh.
Topics: Adult; Aminopropionitrile; Bangladesh; Bone Diseases; Hip; Humans; Lathyrism; Male; Nervous System D | 1997 |
Type I collagen-phosphophoryn interactions: specificity of the monomer-monomer binding.
Topics: Amino Acid Sequence; Aminopropionitrile; Animals; Binding Sites; Collagen; Dentin; Incisor; Lathyris | 1998 |
Combined osteolathyric effects of beta-aminopropionitrile and penicillamine on Xenopus embryos: statistical comparison with dose-addition and independence.
Topics: Aminopropionitrile; Animals; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Fem | 1999 |
Comparative evaluation of the combined osteolathyritic effects of two nitrile combinations on xenopus embryos.
Topics: Aminoacetonitrile; Aminopropionitrile; Animals; Copper Sulfate; Data Interpretation, Statistical; Do | 2000 |
Analysis of the combined osteolathyritic effects of beta-aminopropionitrile and diethyldithiocarbamate on xenopus development.
Topics: Aminopropionitrile; Animals; Chelating Agents; Copper Sulfate; Ditiocarb; Dose-Response Relationship | 2000 |
Lathyritic activity of isoniazid.
Topics: Aminopropionitrile; Animals; Connective Tissue; Female; Isoniazid; Lathyrism; Nitriles; Propionates; | 1976 |
A high molecular weight species of soluble elastin-proelastin.
Topics: Amino Acid Sequence; Amino Acids; Aminopropionitrile; Animals; Chickens; Circular Dichroism; Collage | 1977 |
[Polarization microscopic observations on the pathologic cartilage matrix].
Topics: Aminopropionitrile; Animals; Cartilage; Cartilage, Articular; Collagen; Epiphyses; Glycosaminoglycan | 1975 |
Collagen synthesis in capsules surrounding dimethylbenzanthracene-induced rat breast tumors and the effect of pretreatment with beta-aminopropionitrile.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminopropionitrile; Animals; Benz(a)Anthracenes; Collagen; Female; | 1979 |
[Influence of x-rays on depolymerization of lathyric collagen fibers reconstituted in vitro].
Topics: Aminopropionitrile; Cold Temperature; Collagen; Gels; Lathyrism; Polymers; Radiation Effects; X-Rays | 1975 |
Observations on the mechanism of 99mTc-labeled phosphate complex uptake in metabolic bone disease.
Topics: Aminopropionitrile; Animals; Bone and Bones; Chronic Kidney Disease-Mineral and Bone Disorder; Dipho | 1976 |
Chronic lathyrism and atheromatosis in the rat. Study of the V.L.D.L. and plasma and arterial wall lipids.
Topics: Aminopropionitrile; Animals; Arteries; Arteriosclerosis; Cholesterol; Chronic Disease; Lathyrism; Li | 1978 |
A chromatographic study of the relative affinities of rat bone and skin collagen alpha1 chains for hydroxyapatite.
Topics: Age Factors; Aminopropionitrile; Animals; Bone and Bones; Chromatography; Collagen; Hydroxyapatites; | 1977 |
[The biochemistry of collagen and the locomotor apparatus. Hereditary diseases of connective tissue and rheumatologic diseases (part 2)].
Topics: Aminopropionitrile; Animals; Bone and Bones; Cattle; Cattle Diseases; Collagen; Collagen Diseases; E | 1977 |
[Chronic lathyrism. Protective effect of pyridinol carbamate on connective tissue lesions in the rat (author's transl)].
Topics: Aminopropionitrile; Animals; Carbamates; Chronic Disease; Connective Tissue; Fibroblasts; Lathyrism; | 1977 |
Changes in chemical composition of chick embryos treated with a beta-xyloside and a lathyrogen.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Body Weight; Chick Embryo; Chondroitin Sul | 1979 |
Chronic lathyrism. Effect of beta aminopropionitrile on the aortic wall in the adult rat.
Topics: Aging; Aminopropionitrile; Animals; Aorta; Connective Tissue; Lathyrism; Rats | 1979 |
Inhibition of mineralization by experimental lathyrism during matrix-induced endochondral bone differentiation.
Topics: Alkaline Phosphatase; Aminopropionitrile; Animals; Bone and Bones; Bone Development; Bone Matrix; Ca | 1979 |
[Action mechanism of various teratogenic lathyrogens].
Topics: Abnormalities, Drug-Induced; Acetonitriles; Aminoacetonitrile; Aminopropionitrile; Animals; Chemical | 1977 |
Aortic lathyrism and atheroma in the rat by prolonged hyperlipidic diet.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Arteriosclerosis; Dietary Fats; Lathyrism; Rats | 1978 |
Peptide excretion in experimental Fanconi syndrome in the rat.
Topics: Aminopropionitrile; Animals; Bone Diseases; Fanconi Syndrome; Lathyrism; Male; Maleates; Peptides; R | 1978 |
Protective effect of pyridinol carbamate in dermal and aortic connective tissue lesions induced by chronic lathyrism.
Topics: Aminopropionitrile; Animals; Aorta; Carbamates; Collagen Diseases; Diet, Atherogenic; Lathyrism; Pyr | 1978 |
Fine structure of the myotendinous junction of lathyritic rat muscle with special reference to connectin, a muscle elastic protein.
Topics: Aminopropionitrile; Animals; Collagen; Lathyrism; Muscle Proteins; Muscles; Myofibrils; Rats; Sarcol | 1978 |
[Chronic lathyrism, prolonged hyperlipidic diet, and atheroma in the rat].
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Arteriosclerosis; Chronic Disease; Diet, Atherogenic; | 1976 |
Nutrition Classics. Journal of the American Chemical Society 76: 2848, 1954. Isolation, structure and synthesis of a lathyrus factor from L. odoratus. E.D. Schilling, F.M. Strong.
Topics: Aminopropionitrile; Chemistry; Glutamates; History, 20th Century; Lathyrism; Plants, Toxic; Wisconsi | 1976 |
Galactosyl transferase assay. Application to experimental atherosclerosis.
Topics: Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Collagen; Diet, Atherogenic; Disease Models, A | 1976 |
Morphologic aspects of experimental esophageal lye strictures. II. Effect of steroid hormones, bougienage, and induced lathyrism on acute lye burns.
Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Burns, Chemical; Dilatation; Disease Models, A | 1977 |
Chemistry of collagen crosslinkng: relationship to aging and nutrition.
Topics: Aging; Aminopropionitrile; Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid; Cattl | 1977 |
[Incorporation of 32P-orthophosphate in aortic phospholipids in chronic lathyrims in the rat].
Topics: Aminopropionitrile; Animals; Aorta; Chronic Disease; Dietary Fats; Lathyrism; Lysophosphatidylcholin | 1976 |
Influence of D-penicillamine and beta-aminopropionitril on the metamorphosis of Rana temporaria.
Topics: Aminopropionitrile; Animals; Bone Development; Dose-Response Relationship, Drug; Larva; Lathyrism; M | 1976 |
The use of large molecular weight compounds to produce local lathyrism in healing wounds.
Topics: Aminopropionitrile; Animals; Chickens; Lathyrism; Molecular Weight; Polymers; Tendon Injuries; Wound | 1975 |
Growth of a plasma cell myeloma in lathyritic mice.
Topics: Aminopropionitrile; Animals; Bone Neoplasms; Exostoses; Female; Femur; Lathyrism; Male; Mice; Mice, | 1975 |
In vitro lipid synthesis by lathyrogen-treated L-929 fibroblasts.
Topics: Acetates; Aminopropionitrile; Cell Line; Fibroblasts; In Vitro Techniques; Lathyrism; Lipids | 1975 |
Alteration of elastic architecture in the lathyritic rat aorta implies the pathogenesis of aortic dissecting aneurysm.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Body Weight; | 1992 |
Analysis of stress-strain curves at fast and slow velocities of loading in vitro in the transverse section of the rat incisor periodontal ligament following the administration of beta-aminopropionitrile.
Topics: Administration, Oral; Alveolar Process; Aminopropionitrile; Animals; Dental Cementum; Dental Stress | 1992 |
[Histochemical model investigations of the action mechanisms of lathyrogenic substances].
Topics: Aminoacetonitrile; Aminopeptidases; Aminopropionitrile; Animals; CD13 Antigens; Diazonium Compounds; | 1991 |
The effects of lathyrogens on intestinal anastomoses in the rat.
Topics: Aminopropionitrile; Anastomosis, Surgical; Animals; Collagen; Intestinal Mucosa; Intestines; Lathyri | 1990 |
BAPN dose dependence of mature crosslinking in bone matrix collagen of rabbit compact bone: corresponding variation of sonic velocity and equatorial diffraction spacing.
Topics: Acetates; Acetic Acid; Aminopropionitrile; Animals; Bone Matrix; Chemical Phenomena; Chemistry, Phys | 1990 |
Effect of lathyrogen on collagen of methylcholanthrene-induced sarcoma of rat.
Topics: Aminopropionitrile; Animals; Collagen; Fibrosarcoma; Lathyrism; Male; Methylcholanthrene; Rats; Rats | 1990 |
Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism.
Topics: Aminocaproates; Aminocaproic Acid; Aminopropionitrile; Animals; Aprotinin; Bone Diseases; Collagen; | 1985 |
Comparison of the effects of two lathyrogens on the reproductive system of the laying hen.
Topics: Aminopropionitrile; Animals; Chickens; Diet; Eggs; Female; Lathyrism; Ovary; Oviducts; Poultry Disea | 1989 |
Alterations of elastin fibrogenesis by inhibition of the formation of desmosine crosslinks. Comparison between the effect of beta-aminopropionitrile (beta-APN) and penicillamine.
Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chickens; Cross-Linking Reagents; Desmosine; Elasti | 1985 |
Elastin-proteoglycans association revealed by cytochemical methods.
Topics: Aminopropionitrile; Animals; Aorta; Chickens; Elastic Tissue; Elastin; Glycosaminoglycans; Histocyto | 1985 |
Lathyrism in laying hens and increases in egg weight.
Topics: Aminopropionitrile; Animals; Chickens; Eggs; Female; Lathyrism; Poultry Diseases | 1988 |
[Collagen implants].
Topics: Aminopropionitrile; Animals; Collagen; Drug Implants; Lathyrism; Mice; Skin; Skin Transplantation | 1987 |
Nitrogen-dioxide-induced emphysema in rats. Lack of worsening by beta-aminopropionitrile treatment.
Topics: Aminopropionitrile; Analysis of Variance; Animals; Diet; Disease Models, Animal; Elastin; Germ-Free | 1988 |
Experimental lathyrism: exostoses and aneurysmal-like bone cysts of the mandible in the rat.
Topics: Aminopropionitrile; Animals; Bone Cysts; Chronic Disease; Exostoses; Hemorrhage; Lathyrism; Male; Ma | 1987 |
Lathyrogens and the role of collagen in the eruption of rat incisors.
Topics: Aminoacetonitrile; Aminopropionitrile; Animals; Collagen; Female; Lathyrism; Penicillamine; Periodon | 1986 |
The variation of sonic plesio-velocity in dose dependent lathyritic rabbit femurs.
Topics: Aminopropionitrile; Animals; Dose-Response Relationship, Drug; Femur; Lathyrism; Rabbits; Ultrasonog | 1987 |
A biophysical and histological analysis of factors that lead to aortic rupture in normal and lathyritic turkeys.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Rupture; Brachiocephalic Trunk; Collagen; Elast | 1987 |
The effect of a lathyritic diet on the sensitivity of tendon to strain rate.
Topics: Aging; Aminopropionitrile; Animals; Biomechanical Phenomena; Lathyrism; Rats; Rats, Inbred F344; Ten | 1985 |
Histamine and collagen levels in the lathyritic chick embryos after administration of 48/80.
Topics: Aminopropionitrile; Animals; Bone and Bones; Chick Embryo; Collagen; Histamine; Lathyrism; p-Methoxy | 1985 |
Production of atherosclerosis in lathyritic aortas of rats.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Cholesterol; Diet, Atherogeni | 1970 |
Fetal outcome from prolonged versus acute drug administration in the pregnant rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Collagen; Demyelinating Dise | 1972 |
Bone ash, duodenal 45Ca absorption and calcium-binding protein in chicks fed lathyrogens.
Topics: Aminopropionitrile; Animals; Body Weight; Bone and Bones; Calcium; Calcium Radioisotopes; Chickens; | 1974 |
[Increase in connective tissue permeability during experimental lathyrism].
Topics: Aminopropionitrile; Animals; Connective Tissue; Lathyrism; Mice; Permeability; Skin | 1974 |
Acid mucopolysaccharides of chick-embryo cartilage in osteolathyrism.
Topics: Amino Acids; Aminopropionitrile; Animals; Bone Diseases; Cartilage; Chick Embryo; Collagen; Cyanides | 1966 |
Beta-aminopropionitrile and the mucopolysaccharides of embryonic chick aortae.
Topics: Aminopropionitrile; Animals; Aorta; Chick Embryo; Collagen; Electrophoresis; Glycosaminoglycans; Lat | 1967 |
[Studies on the pathogenesis of connective tissue lesions in experimental lathyrism. (Hydroxyproline and hexosamine determination in the urine of lathyristic rats].
Topics: Aminopropionitrile; Animals; Collagen; Collagen Diseases; Connective Tissue; Female; Glycosaminoglyc | 1966 |
Lathyrism in swine.
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Bone and Bones; Cartilage, Ar | 1969 |
Analysis of hexosamine and acid mucopolysaccharides in skins of normal and lathyritic rats.
Topics: Aminopropionitrile; Animals; Collagen; Electrophoresis; Glucosamine; Glycoproteins; Glycosaminoglyca | 1970 |
Sulfate metabolism in lathyrism and aging.
Topics: Aging; Aminopropionitrile; Animals; Aorta; Brain; Cartilage; Collagen; Elastin; Glycosaminoglycans; | 1971 |
Changes in the thermal decomposition of aorta, tendon and articular cartilage in experimental lathyrism.
Topics: Aminopropionitrile; Animals; Aorta; Cartilage, Articular; Collagen; Elastin; Fumarates; Glycosaminog | 1971 |
Biosynthesis of collagen cross-links in cultured 3 T6 fibroblasts; effect of lathyrogens and ascorbic acid.
Topics: Aminopropionitrile; Animals; Ascorbic Acid; Borohydrides; Carbon Isotopes; Cell Line; Collagen; Conn | 1972 |
Alterations in glycosaminoglycan metabolism in beta-aminopropionitrile-treated chick embryos.
Topics: Acetates; Adenosine Triphosphate; Aminopropionitrile; Animals; Carbon Radioisotopes; Cartilage; Chic | 1973 |
Isolation and characterization of a collagen from chick cartilage containing three identical alpha chains.
Topics: Alanine; Amino Acids; Aminopropionitrile; Animals; Carbohydrates; Cartilage; Chickens; Chromatograph | 1971 |
Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo. II. Morphological and physical properties of collagen containing the analogue.
Topics: Achilles Tendon; Amino Acids; Aminopropionitrile; Animals; Chick Embryo; Chromatography, Gel; Collag | 1971 |
Lung collagen composition and synthesis. Characterization and changes with age.
Topics: Age Factors; Amino Acids; Aminopropionitrile; Animals; Animals, Newborn; Carbon Radioisotopes; Colla | 1974 |
The effect of antirheumatic drugs on the extractable collagen in lathyric chick embryos.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Chick Embryo; Chloroquine; Collagen; Hydro | 1968 |
Copper and amine oxidases in connective tissue metabolism.
Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Benzyl Compounds; Binding Sites; Cattle; Chickens; | 1974 |
[Chronic lathyrism: inhibitory effect of pyridinol carbamate on aortic atheroma in the rat (author's transl)].
Topics: Aminopropionitrile; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Chronic Disease; Diet, Athero | 1974 |
Lathyritic cornea. An optico-mechanical study.
Topics: Aminopropionitrile; Animals; Birefringence; Collagen; Cornea; Elasticity; Lathyrism; Light; Male; Po | 1974 |
Lathyrogenic activity of 2 (2-cyanoethyl)-3-isoxazolin-5-one from Lathyrus odoratus seedlings.
Topics: Aminopropionitrile; Animals; Bone Diseases, Developmental; Lathyrism; Male; Plant Extracts; Plants; | 1974 |
[Osteolathyrism: morphometrical, histochemical, and microradiographical investigations on an experimental bone disease (author's transl)].
Topics: Aminopropionitrile; Animals; Bone Development; Bone Diseases, Developmental; Histocytochemistry; Lat | 1974 |
Aortic lathyrism: ultrastructural study of lesions in the aortic wall and the protective effect of pyridinol carbamate.
Topics: Aging; Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Carbamates; Dietary Fats; Histiocytes; | 1974 |
Effect of certain flavonoids on the cross-linking of lathyritic collagen.
Topics: Aminopropionitrile; Animals; Collagen; Flavonoids; Lathyrism; Rats; Skin | 1974 |
Effect of flavonoids on the manifestations of experimental osteolathyrism.
Topics: Aminopropionitrile; Animals; Flavonoids; Lathyrism; Rats | 1974 |
[Lathyrism and atherogenic diet in rats (importance of simultaneous parietal and lipid disorders in atherogenesis)].
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Diet, Ather | 1972 |
Effect of certain salts on cross-linking of lathyritic collagen.
Topics: Aminopropionitrile; Animals; Collagen; Cryotherapy; Lathyrism; Rats; Salicylates; Skin; Thiosulfates | 1972 |
Collagen heterogeneity within different growth regions of long bones of rachitic and non-rachitic chicks.
Topics: Amino Acids; Aminopropionitrile; Animals; Bone and Bones; Calcification, Physiologic; Chickens; Chro | 1972 |
Isolation of a soluble elastin from lathyritic chicks.
Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chickens; Elastin; Electrophoresis; Iodine Isotopes | 1972 |
[Healing of bone lesions in experimental lathyrism].
Topics: Aminopropionitrile; Animals; Bone Regeneration; Femur; Lathyrism; Rats; Wound Healing | 1972 |
Cell proliferation and cell function of the mesenchymal cells of lathyritic rats, as revealed by the nuclear size.
Topics: Aminopropionitrile; Animals; Cell Division; Cell Nucleus; Female; Lathyrism; Maternal-Fetal Exchange | 1972 |
[Inhibition of elastic fiber formation by beta-aminopropionitrile (electron microscopic study)].
Topics: Aminopropionitrile; Animals; Chick Embryo; Elastic Tissue; Elastin; Lathyrism; Microscopy, Electron; | 1973 |
Microchemical determination of enzyme activities in the lathyritic chick embryo aorta.
Topics: Acid Phosphatase; Alkaline Phosphatase; Aminopropionitrile; Animals; Aorta; Chick Embryo; Elastic Ti | 1973 |
Some studies on the etiology of inguinal hernia.
Topics: Aminopropionitrile; Animals; Collagen; Hernia, Inguinal; Lathyrism; Ligation; Male; Metabolic Diseas | 1973 |
The effects of lathyrism on renal chemistry, anatomy and function.
Topics: Aminopropionitrile; Animals; Basement Membrane; Collagen; Histocytochemistry; Hydroxyproline; Kidney | 1973 |
[Chronic lathyrism. Experimental model of the ageing of the connective tissue in man (author's transl)].
Topics: Aging; Aminopropionitrile; Animals; Aorta; Blood Vessels; Connective Tissue; Coronary Disease; Diabe | 1973 |
Use of large-molecular-weight compounds to produce local lathyrism in healing wounds.
Topics: Aminopropionitrile; Animals; Chick Embryo; Cicatrix; Disease Models, Animal; Lathyrism; Penicillamin | 1973 |
The timecourse of collagen cross-linking.
Topics: Amino Acids; Aminopropionitrile; Animals; Binding Sites; Chromatography, Ion Exchange; Collagen; Lat | 1974 |
Studies on matrix proteins of normal and lathyritic rat bone and dentine.
Topics: Amino Acids; Aminopropionitrile; Animals; Bone and Bones; Bone Matrix; Chromatography; Collagen; Den | 1974 |
Collagen defects in genetic disorders of connective tissue.
Topics: Aminopropionitrile; Chemical Phenomena; Chemistry; Collagen; Ehlers-Danlos Syndrome; Homocystinuria; | 1974 |
Identification of two interchain crosslinks of bone and dentine collagen.
Topics: Aldehydes; Aminopropionitrile; Animals; Autoanalysis; Bone and Bones; Cattle; Chemical Phenomena; Ch | 1969 |
[Experimental lathyrism. Simultaneous changes in skin and aortic connective tissue].
Topics: Aminopropionitrile; Animals; Aorta; Collagen; Connective Tissue; Elastic Tissue; Female; Fibroblasts | 1971 |
[Experimental lathyrism. The aortic wall during chronic poisoning with an atherogenic diet].
Topics: Aminopropionitrile; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Diet, Atherogenic; Elastic Ti | 1971 |
Angiolathyrism. III. Vasa vasorum in experimental dissecting aortic aneurysm.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm; Aortic Dissection; Histocytochemistry; Lathyrism; Male | 1968 |
[Formation of an ectopic bone in the temporal muscle following treatment with beta-aminopropionitrile].
Topics: Aminopropionitrile; Animals; Lathyrism; Masticatory Muscles; Ossification, Heterotopic; Rats | 1967 |
Production of arterial hemosiderosis in rhesus monkeys following the ingestion of -aminopropionitrile.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Arteries; Body Weight; Collagen; Disease Models, Anim | 1971 |
Experimental neurolathyrism in monkeys.
Topics: Amino Acids; Aminopropionitrile; Animals; Haplorhini; Lathyrism; Paralysis | 1971 |
Diseases of connective and vascular tissues. IV. The molecular basis for lathyrism.
Topics: Acetaldehyde; Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Carbon Isotopes; Collagen; Co | 1972 |
[Effect of some hormones on the formation of cross-links in the collagen of rats subjected to the activity of lathyrogenic factors].
Topics: Aminopropionitrile; Animals; Collagen; Estradiol; Hormones; Lathyrism; Prednisolone; Rats; Skin; Thy | 1972 |
Non-aggregated tropocollagen at physiological pH and ionic strength. A chemical and physico-chemical characterization of tropocollagen isolated from the skin of lathyritic rats.
Topics: Amino Acids; Aminopropionitrile; Animals; Collagen; Diffusion; Electrophoresis, Disc; Hexoses; Hydro | 1972 |
Caution against the use of lathyrogens.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Aneurysm; Animals; Arteriosclerosis; Bone Diseases; | 1972 |
Ectopia cordis (ectocardia) and gastroschisis induced in rats by maternal administration of the lathyrogen, beta-aminopropionitrile (BAPN).
Topics: Abdomen; Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Female; Fetus; Gestational Age; H | 1972 |
Collagen heterogeneity. High resolution separation of native ( 1(I) 2 2 and ( 1(II) 3 and their component chains.
Topics: Amino Acids; Aminopropionitrile; Animals; Cartilage; Chemical Precipitation; Chickens; Chromatograph | 1972 |
A new approach to the control of esophageal stenosis.
Topics: Aminopropionitrile; Animals; Chemical Phenomena; Chemistry, Physical; Collagen; Dogs; Esophageal Ste | 1972 |
Studies on protocollagen: identification of a precursor of proto alpha 1.
Topics: Aminopropionitrile; Animals; Bone and Bones; Chick Embryo; Chromatography, Gel; Chromatography, Ion | 1971 |
Prevention of esophageal stenosis with induced lathyrism.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Dogs; Esophageal Stenosis; Granulation Tissue; Lath | 1971 |
Experimental lathyrism: inhibition of beta-alanine incorporation by beta-aminopropionitrile.
Topics: Alanine; Aminopropionitrile; Carbon Isotopes; Cell Line; Cells, Cultured; Fibroblasts; Lathyrism | 1971 |
The effect of lathyrism on bone collagen metabolism in tissue culture.
Topics: Aminopropionitrile; Animals; Collagen; Culture Techniques; Lathyrism; Mice; Nitriles | 1968 |
The effect of a lathyrogenic agent on the synthesis and degradation of mouse bone collagen in tissue culture.
Topics: Aminopropionitrile; Animals; Bone and Bones; Collagen; Culture Techniques; Frontal Bone; Lathyrism; | 1968 |
The effect of lathyrogens on connective tissue.
Topics: Aminopropionitrile; Animals; Chick Embryo; Connective Tissue; Lathyrism; Nitriles; Rats | 1969 |
Platelet aggregation by lathyric collagen.
Topics: Aminopropionitrile; Animals; Blood Coagulation; Blood Platelets; Collagen; Lathyrism; Rats | 1969 |
Wound contraction in experimental lathyrism.
Topics: Aminopropionitrile; Animals; Biomechanical Phenomena; Collagen Diseases; Lathyrism; Male; Microscopy | 1969 |
Remodelling of periosteal lesions induced by surgical stimulation or beta-aminopropionitrile administration.
Topics: Aminopropionitrile; Animals; Bone and Bones; Exostoses; Female; Lathyrism; Male; Muscles; Nitriles; | 1969 |
Effect of anti-inflammatory drugs on leucocyte migration and protein exudation into carboxymethylcellulose pouch in lathyritic rats.
Topics: Adrenal Glands; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cell | 1969 |
The characterization of lathyrism in the experimental animal.
Topics: Aminopropionitrile; Animals; Bone and Bones; Collagen; Lathyrism; Male; Rats; Skin | 1970 |
Comparative effects of an osteolathyrogen and a neurolathyrogen on brain and connective tissues.
Topics: Acid Phosphatase; Aminopropionitrile; Animals; Bone Diseases; Brain; Cathepsins; Chorea; Citrates; C | 1970 |
Growth of Enterobacter aerogenes in a lathyrogen-containing medium.
Topics: Aminopropionitrile; Culture Media; Enterobacter; Fumarates; Lathyrism; Models, Biological; Nitriles; | 1970 |
Dysostosis in adult rats after prolonged beta-aminopropionitrile feeding.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Autopsy; Body Weight; Diet; Disease Models, Ani | 1970 |
Enzymatic cross-linking of bone collagen.
Topics: Aminopropionitrile; Animals; Bone and Bones; Chickens; Collagen; Lathyrism; Lysine; Oxidoreductases | 1970 |
Cataractogenic nnd lathyrogenic effects of N-phenyl-beta-hydrazinopropionitriles and related compounds in rats.
Topics: Aminopropionitrile; Animals; Animals, Newborn; Biopsy; Cataract; Collagen; Fumarates; Hydrazines; Hy | 1970 |
Isolation of two distinct collagens from chick cartilage.
Topics: Amino Acids; Aminopropionitrile; Animals; Bone and Bones; Cartilage; Chemical Phenomena; Chemistry; | 1970 |
The effect of lathyrogens on developing mid-facial structures in the rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Diet; Female; Jaw Abnormalities; Lathyrism | 1970 |
Effect of certain vitamins on the formation of cross-links in the collagen of lathyritic rats.
Topics: Aldehydes; Aminopropionitrile; Animals; Chromatography; Collagen; Lathyrism; Pantothenic Acid; Rats; | 1971 |
The effect of lathyrogens on developing midfacial structures in the rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cartilage; Cleft Palate; Diet; Face; Femal | 1971 |
Characterization of the aldehydes present on the cyanogen bromide peptides from mature rat skin collagen.
Topics: Adipates; Aging; Aldehydes; Amines; Amino Acids; Aminopropionitrile; Animals; Boron Compounds; Carbo | 1971 |
Isolation and characterization of the cyanogen bromide peptides from the alpha-1 chain of rat skin collagen.
Topics: Amino Acids; Aminopropionitrile; Animals; Autoanalysis; Bromides; Chromatography, Ion Exchange; Chro | 1967 |
Aortic sulfur 35 uptake in experimental lathyrism.
Topics: Aminopropionitrile; Animals; Aorta; Autoradiography; Lathyrism; Nitriles; Rats; Sulfur Isotopes | 1968 |
The effect of postlathyritic medial scar on the progression of experimental atherosclerosis in rats.
Topics: Aminopropionitrile; Animal Nutritional Physiological Phenomena; Animals; Aorta; Arteriosclerosis; Ba | 1968 |
Studies on collagen crosslinking in vivo.
Topics: Acrylic Resins; Aminopropionitrile; Animals; Chemical Phenomena; Chemistry, Physical; Collagen; Elec | 1968 |
Molecular diseases of connective and vascular tissues. 3. The aldehyde content of normal and lathyritic soluble collagen.
Topics: Aldehydes; Amino Acids; Aminopropionitrile; Animals; Autoanalysis; Azo Compounds; Collagen; Electrop | 1968 |
Influence of cystine supplements on the incidence of aortic rupture in rats fed beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Aortic Rupture; Cystine; Diet; Lathyrism; Methionine; Nitriles; Rats | 1968 |
Desmosine biosynthesis: nature of inhibition by D-penicillamine.
Topics: Adipates; Amino Acids; Aminopropionitrile; Animals; Aorta; Chick Embryo; Collagen; Connective Tissue | 1968 |
The influence of sodium salicylate on the metabolism of collagen in the lathyritic rat.
Topics: Aminopropionitrile; Animals; Carbon Isotopes; Collagen; Hydroxyproline; Lathyrism; Male; Nitriles; P | 1968 |
Lathyrism and aging.
Topics: Aging; Aminopropionitrile; Animals; Collagen; Femur; Injections, Intraperitoneal; Lathyrism; Methods | 1968 |
The effect of lathyrogens on the rate of collagen fibril formation and dissolution.
Topics: Aminopropionitrile; Animals; Chemical Phenomena; Chemistry; Collagen; Hot Temperature; Kinetics; Lat | 1968 |
Effect of controlled lathyrism following repair of flexor tendons in man.
Topics: Aminopropionitrile; Collagen; Humans; Hydroxyproline; Lathyrism; Nitriles; Tendon Injuries | 1968 |
[Electron microscopic study of the distal epiphyseal cartilage of the femur of the chick embryo. 2. On the epiphyseal cartilage in experimental osteolathyrism].
Topics: Aminopropionitrile; Animals; Cartilage; Chick Embryo; Collagen; Epiphyses; Femur; Lathyrism; Microsc | 1968 |
A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. II. Functional groups involved in the interaction process.
Topics: Aldehydes; Amino Acids; Aminopropionitrile; Animals; Chemical Phenomena; Chemistry; Collagen; Dialys | 1969 |
Some studies on the effects of beta-aminopropionitrile in patients with injured flexor tendons.
Topics: Aminopropionitrile; Collagen; Humans; Lathyrism; Nitriles; Tendon Injuries; Wound Healing | 1969 |
In vitro enzymic biosynthesis of two inter-chain crosslinks of bone collagen.
Topics: Aldehydes; Amino Acids; Aminopropionitrile; Animals; Bone and Bones; Boron Compounds; Cell-Free Syst | 1969 |
Platelet aggregation by lathyric collagen.
Topics: Aminopropionitrile; Animals; Blood Coagulation; Blood Platelets; Collagen; Lathyrism; Rats | 1969 |
[Fractionation of hydroxyproline-containing urinary peptides by Sephadex gel filtration].
Topics: Adolescent; Aminopropionitrile; Animals; Arthritis; Bone Diseases; Child; Child, Preschool; Chromato | 1969 |
Experimental lathyrism: in vitro model systems.
Topics: Aminopropionitrile; Cell Division; Cell Line; Connective Tissue; Culture Techniques; Fibroblasts; La | 1969 |
Characterization of the alpha-chains of chick skin collagen and the nature of the NH2-terminal cross-link region.
Topics: Adipates; Amino Acids; Aminopropionitrile; Animals; Autoanalysis; Bromine; Cellulose; Chemical Pheno | 1969 |
The biosynthesis of elastin cross-links. The effect of copper deficiency and a lathyrogen.
Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chick Embryo; Copper; Culture Techniques; Cyanides; | 1965 |
Accumulation of a collagen precursor in the skin of penicillamine-treated rats.
Topics: Aminopropionitrile; Animals; Collagen; In Vitro Techniques; Lathyrism; Penicillamine; Proline; Rats; | 1965 |
Comparison of copper deficiency and lathyrism in turkey poults.
Topics: Aminopropionitrile; Animals; Aorta; Copper; Cyanides; Deficiency Diseases; Lathyrism; Poultry | 1966 |
Naturally occurring toxic factors in plants and animals used as food.
Topics: Aminopropionitrile; Cyanides; Food Analysis; Glycosides; Goiter; Humans; Hypertension; Lathyrism; Me | 1966 |
Effect of different lathyrogens upon tissue responses in rats.
Topics: Aminopropionitrile; Animals; Aortic Rupture; Bone and Bones; Cyanides; Lathyrism; Mercaptoethylamine | 1966 |
Enzymatic determination in serum of lathyritic and prednisone-treated lathyritic rats.
Topics: Alanine Transaminase; Aminopropionitrile; Animals; Aspartate Aminotransferases; Cyanides; Fructose-B | 1966 |
Lathyrism in the fetal rat. Evidence for impairment of elastin formation.
Topics: Aminopropionitrile; Animals; Congenital Abnormalities; Cyanides; Elastin; Female; Fetal Death; Fetal | 1966 |
The nature of the collagen defect in lathyrism.
Topics: Aldehydes; Aminopropionitrile; Animals; Chick Embryo; Chromatography; Collagen; Cyanides; Electropho | 1966 |