Page last updated: 2024-09-27

Fusariosis

OPPORTUNISTIC INFECTIONS with the soil fungus FUSARIUM. Typically the infection is limited to the nail plate (ONYCHOMYCOSIS). The infection can however become systemic especially in an IMMUNOCOMPROMISED HOST (e.g., NEUTROPENIA) and results in cutaneous and subcutaneous lesions, fever, KERATITIS, and pulmonary infections.

Synonyms(1)

Synonym
Fusariosis

Research Excerpts

Overview

ExcerptReference
"Fusariosis is an emerging infectious complication of immune deficiency, but models to study this infection are lacking."( Breger, J; Coleman, JJ; Fuchs, BB; Muhammed, M; Mylonakis, E; Wu, MP, 2012)
"Disseminated fusariosis is an uncommon clinical condition in immunocompromised patients."( Betânia, CA; Macêdo, DP; Neves, RP; Silva, GM; Silveira, AR, 2013)
"Invasive fusariosis is an infection with Fusarium spp."( Gunasekara, TA; Nagahawatte, A; Ranawaka, RR, 2015)
"Disseminated fusariosis is a life-threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies."( Bouchnerova, J; Hadrabova, M; Kocmanova, I; Lengerova, M; Mayer, J; Palackova, M; Pavlovsky, Z; Racil, Z; Ricna, D; Volfova, P; Weinbergerova, B, 2016)
"Fusariosis is an opportunistic infection, caused by a filamentous fungus, found on plants and in soil."( Bonardel, G; Guernou, M; Lussato, D; Queneau, M; Seban, RD, 2017)
"Fusariosis is the second most common mould infection after aspergillosis, and keratitis is the most encountered implantation infection in immunocompetent individuals."( Al-Hatmi, AMS; Bonifaz, A; Meis, JF; Ranque, S; Sybren de Hoog, G; Verweij, PE, 2018)
"Disseminated fusariosis is a fatal infection in immunocompromised hosts."( Fujiwara, T; Hasegawa, D; Ishida, T; Kamei, K; Kishimoto, K; Kosaka, Y; Kozaki, A; Muraosa, Y; Nakamura, S; Saito, A; Tahara, T; Tamura, A; Uemura, S; Yamamoto, N, 2018)
"Fusariosis is an opportunistic fungal infection that affects mostly leukemic and hematopoietic stem cell transplant patients."( Carneiro, MP; Chaves, ALDS; Lopes, FPPL; Machado, LS; Schirmer, MR, 2018)
"Disseminated fusariosis is now the second most frequent lethal fungal infection after aspergillosis especially in neutropenic patients with hematologic malignancy."( Banfalvi, G, 2018)
"Fusariosis is an infection that is caused by fungi of the Fusarium genus."( Alexandrino Becker, TC; Costa, MI; Jarros, IC; Kischkel, B; Negri, M; Svidzinski, TIE; Veiga, FF; Vilugron Rodrigues, FA, 2019)
"Fusariosis is a critical infectious complication that can develop in immunocompromised hosts, mainly under conditions of prolonged neutropenia, and is often disseminated and associated with a high mortality rate."( Fukuhara, N; Harigae, H; Ichikawa, S; Okitsu, Y; Onishi, Y; Onodera, K; Watanabe, S, 2020)
"Fusariosis is the second most common mold infection after aspergillosis, and keratomycosis is the most encountered implantation infection."( Cai, W; Li, J; Li, X; Lu, S; Ma, J; Shi, M; Xi, L; Zhang, J, 2020)
"Invasive fusariosis is a rare fungal infection in solid organ transplantation."( Chayakulkeeree, M; Chongtrakool, P; Yamasmith, E, 2020)
"Invasive fusariosis is associated with marked morbidity and mortality in immunocompromised hosts, and clinical outcomes are poor with conventional therapy."( Badali, H; Cañete-Gibas, C; Fan, H; Garcia, V; Mele, J; Mermella, B; Patterson, H; Sanders, C; Wiederhold, NP, 2021)
"Invasive fusariosis is a serious infection affecting mostly patients with haematologic malignancies and hematopoietic cell transplant recipients."( Guarana, M; Nouér, SA; Nucci, M, 2021)
"The EQUAL score Fusariosis is a tool that may help clinicians to measure guidelines adherence."( Guarana, M; Nouér, SA; Nucci, M, 2021)
"Therefore, invasive fusariosis is rare after solid organ transplantation."( Becker, T; Braun, F; Heß, K; Stropnicky, P, 2022)
"However, CNS fusariosis is rare and often happens due to hematogenous dissemination from other sites."( Alavi Darazam, I; Hakamifard, A; Jamali, E; Javandoust Gharehbagh, F; Khodavaisy, S; Sharifi, G, 2022)
"Thus, fusariosis is more widespread among the Testudines than previously reported and is not limited to sea environments, findings of particular conservation concern."( Carranco, AS; Gillingham, MAF; Romo, D; Sommer, S; Torres, ML; Wilhelm, K, 2022)
"Disseminated fusariosis is a rare and fatal infection in immunocompromised patients."( Hu, J; Li, H; Li, T; Song, Y; Yao, X; Zhong, L, 2022)
"Disseminated fusariosis is a rare and fatal infection in immunocompromised patients."( Hu, J; Li, H; Li, T; Song, Y; Yao, X; Zhong, L, 2022)
"Fusariosis is a serious threat."( Aguilar-Zapata, D; Barragán-Reyes, A; Camacho, A; Cendejas, RF; Cornejo-Juárez, P; Guzmán, JMF; Hernández, MLG; Jácome, LEL; Juárez-Hernández, E; Nava-Ruiz, A; Ontañón-Zurita, D; Perales-Martínez, D; Reséndiz-Sánchez, J; Rincón-Zuno, J; Rivera-Martínez, NE, 2023)

Context

ExcerptReference
"Fusariosis has been reported sporadically in fish and other aquatic organisms, but identification has often been limited to the genus level based solely on morphologic features."( Berliner, AL; Camus, AC; Clauss, TM; Knowles, S; Marancik, DP; O'Donnell, K; Salter, CE; Sutton, DA, 2012)
"Disseminated fusariosis has emerged as a significant, usually fatal infection in immunocompromised hosts despite antifungal treatment."( Brasil, RA; de Angelis, DA; de Matos Castro e Silva, D; de Souza Carvalho Melhem, M; dos Anjos Martins, M; Pereira, GH; Szeszs, MW, 2013)
"Disseminated fusariosis has a high mortality and is predominantly observed in patients with leukemia."( Al-Hatmi, AS; Cilo, BD; Curfs-Breuker, I; Ener, B; Ersal, T; Meis, JF; Özkalemkaş, F; van Diepeningen, AD, 2015)
"Fusariosis have been increasing in Colombia in recent years, but its epidemiology is poorly known."( Amézquita, A; Cano, LE; Cano-Lira, JF; Cárdenas, M; Celis, A; De Bedout, C; de García, MC; Espinel-Ingroff, A; García, AM; Guarro, J; Guevara-Suarez, M; Motta, A; Restrepo, S; Sopo, L, 2016)
"Invasive fusariosis has a high mortality and is predominantly observed in patients with leukemia."( Dallé Rosa, P; Goldani, LZ; Meneghello Fuentefria, A; Ramirez-Castrillon, M; Valente, P; Van Diepeningen, AD, 2018)
"Fusariosis has presented a significant increase in their incidence in the last years."( da Rosa Monte Machado, G; de Andrade, SF; Henning Vainstein, M; José Alves, R; Lettieri Teixeira, M; Lopes, W; Meneghello Fuentefria, A; Neiva Lavorato, S, 2022)

Treatment

ExcerptReference
"The difficulty in treating cases of fusariosis in the human medical clinic exemplifies this situation, because when Fusarium spp."( de Andrade, SF; de Chaves, MA; Fernanda Andrzejewski Kaminski, T; Ferreira do Amaral, T; Flavio Souza de Oliveira, L; Fuentefria, AM; Monteiro da Silva Rodrigues Coutinho, N; Teixeira, ML, 2020)

Research

Studies (435)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (0.23)23.3326
1990's0 (0.00)12.5806
2000's1 (0.23)18.1394
2010's349 (80.23)28.8240
2020's84 (19.31)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low20
ammonium hydroxide0low10
carbamates0low20
salicylic acid0low20
formaldehyde0low20
indoleacetic acid0low10
methanol0low10
melatonin0low10
nickel0low10
phenol0low10
phosphorylcholine0low20
alexidine0low10
ciclopirox0low10
ciprofloxacin0low10
clioquinol0low10
fluconazole0low40
gentamicin0low10
miltefosine0low20
ketoconazole0low10
miconazole0low10
mitoxantrone0low20
pyrimethamine0low10
sulfadiazine0low10
prednisolone0low20
benzimidazole0low20
prednisolone acetate0low10
biguanides0low30
sucrose0low10
galactose0low90
cytarabine0low20
valine0low10
arginine0low10
chloroacetamide0low10
methyleugenol0low10
pyrroles0low10
isoxazoles0low10
azacitidine0low10
fusarium0medium3924
alpha-aminopyridine0low10
c.i. 425100low10
zinc oxide0low10
vantocil0low20
silver0low20
cadmium0low10
gold0low10
trolamine salicylate0low20
carbendazim0low20
fluorides0low10
etoposide0low10
deoxynivalenol0low60
idarubicin0low10
loceryl0low10
itraconazole0low130
adenosine0low10
trazodone hydrochloride0low110
cephalosporin c0low10
propamidine isethionate0low10
triazoles0medium391
fluorodeoxyglucose f180low20
magnolol0low10
honokiol0low10
clarithromycin0low10
n-methyladenosine0low10
cobalt0low10
beauvericin0low10
clofarabine0low10
1,3,4-thiadiazole0low10
cucurbitaceae0low10
levofloxacin0low10
anidulafungin0low20
lignin0low20
deoxycholic acid0low30
trimethoprim, sulfamethoxazole drug combination0low10
povidone-iodine0low10
epiglucan0low60
laminaran0low10
cellulase0low10
lignans0low10
ergosterol0low10
mycophenolic acid0low10
posaconazole0low110
l 743,8720low50
micafungin0low20
efinaconazole0low30
riboflavin0low30
bromochloroacetic acid0low10
stilbenes0low10
sesquiterpenes0low20
terbinafine0low120
fumonisin b10low50
nnd 5020low30
laccase0low10
galactomannan0low90
amphotericin b0low580
zearalenone0low30
phenylephrine hydrochloride0low10
3-acetyldeoxynivalenol0low10
boron0low10
cefepime0low10
cefotaxime0low10
c.i. fluorescent brightening agent 280low10
coomassie brilliant blue0low10
isavuconazole0low10
chlorhexidine0low10
mocetinostat0low20
15-acetyldeoxynivalenol0low10
gentamicin b0low10
cellulose0low10
chlorophyll a0low20
3-(3-(4-((pyridin-2-yloxy)methyl)benzyl)isoxazol-5-yl)pyridin-2-amine0low10
amphotericin b, deoxycholate drug combination0low30
pci 327650low20
mannans0low90
piperidines0low20
fusariumin0low20
ascorbic acid0low10
salicylates0low10
warfarin0low20
tigecycline0low10
3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid0low10
t-2 toxin0low20
acyclovir0low10
valacyclovir0low10
eye0low10
metallothionein0low10

Protein Targets (1,276)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
Chain A, Ferritin light chain8008
Thymidine kinase 0101
thioredoxin reductase120012
phosphopantetheinyl transferase8008
GLS protein4004
TDP1 protein320032
Smad3120012
thyroid stimulating hormone receptor6006
EWS/FLI fusion protein160016
arylsulfatase A6006
euchromatic histone-lysine N-methyltransferase 2190019
activating transcription factor 6110011
Histone H2A.x130013
Bloom syndrome protein isoform 17007
hemoglobin subunit beta2002
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
lamin isoform A-delta10210021
Solute carrier family 22 member 1 0405
ATP-binding cassette sub-family C member 3018018
Multidrug resistance-associated protein 4018018
Solute carrier family 22 member 60203
Bile salt export pump0404
Bile salt export pump023023
Purine nucleoside phosphorylase0202
Thymidine kinase, cytosolic0102
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 014116
Cytochrome P450 2J20202
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60203
Thymidine kinase 0101
Solute carrier family 22 member 80204
Canalicular multispecific organic anion transporter 1017018
Thymidine kinase0202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma250025
AR protein320032
nuclear receptor subfamily 1, group I, member 3230023
cytochrome P450 family 3 subfamily A polypeptide 4270027
glucocorticoid receptor [Homo sapiens]290029
estrogen-related nuclear receptor alpha290029
pregnane X nuclear receptor220022
estrogen nuclear receptor alpha370037
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
nuclear factor erythroid 2-related factor 2 isoform 2140014
heat shock protein beta-19009
importin subunit beta-1 isoform 15005
snurportin-15005
tumor susceptibility gene 101 protein2002
GTP-binding nuclear protein Ran isoform 13003
Voltage-dependent calcium channel gamma-2 subunit180018
Cyclin-dependent kinase 10213
Heat shock protein HSP 90-beta0101
Glutamate receptor 2191020
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 4391010
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 5140014
Ataxin-2180018
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 46006
retinoid X nuclear receptor alpha220022
NPYLR7B0044
IDH1130013
glycogen synthase kinase-3 beta isoform 10022
mitogen-activated protein kinase 1100010
flap endonuclease 18008
nuclear receptor ROR-gamma isoform 1100010
peripheral myelin protein 22150015
survival motor neuron protein isoform d9009
high affinity choline transporter 1 isoform a0303
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Rap guanine nucleotide exchange factor 32002
Epidermal growth factor receptor0527
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20415
Insulin receptor0012
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0235
Platelet-derived growth factor receptor beta0113
Adenosine receptor A30629
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10012
Inosine-5'-monophosphate dehydrogenase 20314
Endoplasmin0224
Inosine-5'-monophosphate dehydrogenase 1 0303
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A10213
Adenosine receptor A30202
Adenosine receptor A2a0428
Adenosine receptor A2b0013
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A106210
Adenosine receptor A2a0213
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0304
Adenosine receptor A10011
Adenosine kinase0012
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0304
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0304
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0304
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
retinoic acid nuclear receptor alpha variant 1270027
thyroid stimulating hormone receptor130013
thyroid hormone receptor beta isoform 2240024
Botulinum neurotoxin type A 0202
Neutrophil cytosol factor 10101
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0114
Kappa-type opioid receptor0013
Mu-type opioid receptor0011
Tyrosine-protein kinase 0011
Chain A, Cruzipain6006
interleukin 86006
farnesoid X nuclear receptor170017
peroxisome proliferator-activated receptor delta140014
vitamin D (1,25- dihydroxyvitamin D3) receptor130013
tumor necrosis factor2002
vitamin D3 receptor isoform VDRA5005
nuclear factor erythroid 2-related factor 2 isoform 1270027
Cytochrome P450 1A20707
Cytochrome P450 3A4015220
Cytochrome P450 2D6010010
Cytochrome P450 2C190809
Nuclear receptor ROR-gamma8008
Potassium voltage-gated channel subfamily H member 2014015
Aurora kinase B0213
Broad substrate specificity ATP-binding cassette transporter ABCG20506
Replicase polyprotein 1ab0101
Cytochrome P450 2C80304
Cytochrome P450 2B60405
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
NFKB1 protein, partial3003
alpha-galactosidase2002
cytochrome P450 2C19 precursor3003
chromobox protein homolog 1140014
DNA polymerase iota isoform a (long)100010
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)6006
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, inducible0102
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase8008
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase7007
GLI family zinc finger 3250025
thioredoxin glutathione reductase6006
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin260026
Polyphenol oxidase 20204
Pancreatic alpha-amylase0202
Albumin0102
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0415
Spike glycoprotein170017
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Beta-lactamase4004
glp-1 receptor, partial140014
pregnane X receptor4004
ATAD5 protein, partial9009
Fumarate hydratase130013
PPM1D protein100010
Thrombopoietin2002
aldehyde dehydrogenase 1 family, member A1150015
estrogen receptor 2 (ER beta)140014
progesterone receptor180018
polyprotein130013
67.9K protein120012
Parkin4004
peroxisome proliferator activated receptor gamma200020
aryl hydrocarbon receptor150015
peripheral myelin protein 22 isoform 13003
cellular tumor antigen p53 isoform a5005
huntingtin isoform 26006
ras-related protein Rab-9A4004
serine/threonine-protein kinase mTOR isoform 14004
urokinase-type plasminogen activator precursor8008
plasminogen precursor8008
urokinase plasminogen activator surface receptor precursor8008
histone acetyltransferase KAT2A isoform 19009
Interferon beta230023
Cellular tumor antigen p53250025
Integrin beta-35005
Integrin alpha-IIb5005
DNA (cytosine-5)-methyltransferase 10101
D(1A) dopamine receptor3003
Multidrug and toxin extrusion protein 10505
Histone-lysine N-methyltransferase EHMT20101
Chain A, GTPase KRas, isoform 2B0011
Chain A, GTPase KRas, isoform 2B0011
Membrane primary amine oxidase 0101
Cytochrome P450 2B10102
Cytochrome P450 1A10102
GTPase KRas0011
Polyunsaturated fatty acid 5-lipoxygenase0102
Glutaminyl-peptide cyclotransferase0101
Lanosterol 14-alpha demethylase0527
Membrane primary amine oxidase0101
Glutaminyl-peptide cyclotransferase0101
nuclear receptor subfamily 1, group I, member 24004
Luciferase7007
caspase 7, apoptosis-related cysteine protease7007
caspase-37007
v-jun sarcoma virus 17 oncogene homolog (avian)130013
thyroid hormone receptor beta isoform a9009
histone deacetylase 9 isoform 33003
Methionine aminopeptidase0101
Fatty-acid amide hydrolase 10202
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0002
Beta-lactamase 0102
Beta-lactamase 0002
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Metallo-beta-lactamase VIM-19 0002
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase0002
Beta-lactamase 0102
Beta-lactamase0001
Solute carrier family 22 member 50101
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase SHV-10002
Beta-lactamase0001
Beta-lactamase0002
Solute carrier family 15 member 10405
Beta-lactamase TEM0102
Beta-lactamase0001
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20202
Metallo-beta-lactamase VIM-130002
Beta-lactamase 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Metallo-beta-lactamase0002
Solute carrier family 15 member 20303
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0002
BlaVIM-1 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase class B VIM-2 0002
Beta-lactamase VIM-1 0002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Albumin0123
Beta-lactamase SHV-10001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Solute carrier family 22 member 70102
Beta-lactamase 0001
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Histamine H3 receptor0001
Solute carrier family 22 member 110101
Solute carrier family 22 member 80101
Solute carrier family 22 member 70101
Chain A, JmjC domain-containing histone demethylation protein 3A7007
Chain A, BCL-2-RELATED PROTEIN A10022
acid sphingomyelinase3003
PAX80001
15-lipoxygenase, partial5005
hypoxia-inducible factor 1 alpha subunit9009
SMAD family member 2100010
USP1 protein, partial100010
SMAD family member 3100010
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
PINK11001
G140014
cytochrome P450 2D6160016
glucocerebrosidase1001
heat shock protein 900011
calcineurin A1, putative0011
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a100010
cytochrome P450 2D6 isoform 15005
hepatocyte nuclear factor 4-alpha isoform 20101
cytochrome P450 2C9 precursor3003
perilipin-50101
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d9009
transcriptional regulator ERG isoform 35005
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 13003
protein AF-9 isoform a0003
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
DNA polymerase kappa isoform 14004
cytochrome P450 3A4 isoform 1100010
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0003
bcl-2-like protein 11 isoform 10022
Gamma-aminobutyric acid receptor subunit pi101011
Synaptojanin-20101
Solute carrier family 22 member 20202
Polyunsaturated fatty acid lipoxygenase ALOX15B5005
Synaptojanin-10101
Solute carrier family 22 member 30303
Glutathione reductase, mitochondrial0204
HLA class I histocompatibility antigen, B alpha chain 140014
72 kDa type IV collagenase0101
Matrix metalloproteinase-90101
Gamma-aminobutyric acid receptor subunit beta-1101011
Gamma-aminobutyric acid receptor subunit delta101011
Gamma-aminobutyric acid receptor subunit gamma-2101011
Gamma-aminobutyric acid receptor subunit alpha-5101011
Gamma-aminobutyric acid receptor subunit alpha-3101011
Gamma-aminobutyric acid receptor subunit gamma-1101011
Gamma-aminobutyric acid receptor subunit alpha-2101011
Gamma-aminobutyric acid receptor subunit alpha-4101011
Gamma-aminobutyric acid receptor subunit gamma-3101011
Trypanothione reductase0101
Gamma-aminobutyric acid receptor subunit alpha-6101011
Alpha-synuclein5005
Histamine H2 receptor6006
Gamma-aminobutyric acid receptor subunit alpha-1101011
Gamma-aminobutyric acid receptor subunit beta-3101011
Gamma-aminobutyric acid receptor subunit beta-2101011
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20202
Rap guanine nucleotide exchange factor 44004
GABA theta subunit101011
Inositol hexakisphosphate kinase 1140014
Gamma-aminobutyric acid receptor subunit epsilon101011
Spermine oxidase0101
cytochrome P450 2C9, partial140014
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
Isocitrate dehydrogenase [NADP] cytoplasmic0101
Lysine-specific demethylase 4B0101
Hypoxia-inducible factor 1-alpha0101
Deoxyhypusine hydroxylase0101
Chain A, 2-oxoglutarate Oxygenase120012
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 19009
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha03214
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0101
DNA gyrase subunit A0202
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0303
streptokinase A precursor0033
ATP-dependent translocase ABCB109011
Solute carrier organic anion transporter family member 1B30505
Solute carrier organic anion transporter family member 1B10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
mu opioid receptor, partial0011
90-kda heat shock protein beta HSP90 beta, partial0202
Microtubule-associated protein tau4004
nonstructural protein 15005
bromodomain adjacent to zinc finger domain 2B2002
LAP40011
MEP20011
polyunsaturated fatty acid lipoxygenase ALOX121001
delta-type opioid receptor0112
kappa-type opioid receptor isoform 10101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
heat shock protein HSP 90-alpha isoform 20205
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Histone deacetylase 30404
Carbonic anhydrase 120203
Carbonic anhydrase 10607
Carbonic anhydrase 20719
Amyloid-beta precursor protein2204
Carbonic anhydrase 30203
Spike glycoprotein0112
Alpha-1B adrenergic receptor0314
Catechol O-methyltransferase0101
Carbonic anhydrase 40304
Carbonic anhydrase 60405
Alpha-1D adrenergic receptor0112
Carbonic anhydrase 5A, mitochondrial0203
Alpha-1A adrenergic receptor0415
Carbonic anhydrase 70203
Histone deacetylase 40303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Histone deacetylase 10404
Carbonic anhydrase 90315
Beta-galactosidase0011
Histone deacetylase 70303
Histone deacetylase 20404
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0303
Carbonic anhydrase 150404
Histone deacetylase 80303
Carbonic anhydrase 130203
Histone deacetylase 60303
Histone deacetylase 90202
Carbonic anhydrase 140203
Histone deacetylase 50303
HSP40, subfamily A [Plasmodium falciparum 3D7]0002
heat shock protein 90, putative0003
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
endonuclease IV2002
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Thymidine kinase 2, mitochondrial0101
Thymidine kinase0101
Thymidylate synthase0001
Thymidine kinase0101
Deoxycytidine kinase0012
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Deoxynucleoside kinase0101
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Vitamin D3 receptor0112
Ileal sodium/bile acid cotransporter0101
G-protein coupled bile acid receptor 10213
Bile acid receptor0011
Prothrombin0001
Regulatory protein E20011
ATP-dependent translocase ABCB10606
DNA topoisomerase 10102
Polyunsaturated fatty acid lipoxygenase ALOX150303
DNA topoisomerase 20002
ATP-dependent translocase ABCB10606
UDP-glucuronosyltransferase 1A1 0103
Serum paraoxonase/arylesterase 10101
Glutamate receptor ionotropic, NMDA 1 0203
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0203
Glutamate receptor ionotropic, NMDA 2B0203
Glutamate receptor ionotropic, NMDA 2C0204
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta01210
Glutamate receptor ionotropic, NMDA 2D0203
Tubulin beta-2B chain0101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Glutamate receptor ionotropic, NMDA 3B0203
Glutamate receptor ionotropic, NMDA 3A0203
apical membrane antigen 1, AMA12002
unnamed protein product0101
Chymotrypsinogen A0303
Beta-lactamase0303
Steroid 17-alpha-hydroxylase/17,20 lyase0505
Heme oxygenase 1 0202
Lanosterol 14-alpha demethylase0134
Aromatase0606
Cytochrome P450 11B1, mitochondrial0303
Cytochrome P450 11B2, mitochondrial0303
Heme oxygenase 20202
Malate dehydrogenase, cytoplasmic0303
Cytochrome P450 1440044
Steroid C26-monooxygenase0044
Steroid C26-monooxygenase0044
Mycocyclosin synthase0022
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0022
Sterol 14-alpha demethylase0033
Sterol 14-alpha demethylase0224
14-alpha sterol demethylase 0033
likely tRNA 2'-phosphotransferase0101
Carbonic anhydrase0101
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Neuraminidase 0101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
TPA: protein transporter TIM100202
lysosomal alpha-glucosidase preproprotein4004
DNA polymerase beta4004
Vpr6006
Polyunsaturated fatty acid 5-lipoxygenase0101
Gamma-aminobutyric acid receptor subunit alpha-10033
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit gamma-20033
Retinoic acid receptor RXR-alpha0012
Cannabinoid receptor 10426
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit alpha-30011
Cannabinoid receptor 2 0213
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit beta-20033
Prostaglandin G/H synthase 20101
Angiotensin-converting enzyme 2 0011
Platelet glycoprotein VI0112
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0022
DNA polymerase III, partial2002
hexokinase-4 isoform 11001
NPC intracellular cholesterol transporter 1 precursor2002
D(1A) dopamine receptor1001
glucokinase regulatory protein1001
eyes absent homolog 2 isoform a1001
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
DNA polymerase eta isoform 13003
M-phase phosphoprotein 83003
muscleblind-like protein 1 isoform 13003
Glutamate receptor 11102
Glutamate receptor 31102
Glutamate receptor 41102
Inositol monophosphatase 14004
Single-stranded DNA cytosine deaminase2002
Peptide deformylase 1A, chloroplastic/mitochondrial0101
Peptide deformylase 0101
GALC protein3003
Estrogen receptor beta0102
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Epoxide hydrolase 10002
Aldo-keto reductase family 1 member B10808
Muscarinic acetylcholine receptor M20606
Cytochrome P450 2C11 0202
Steroid 21-hydroxylase0101
Alpha-2A adrenergic receptor0606
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0101
Indoleamine 2,3-dioxygenase 10202
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Translocator protein0101
Cytochrome P450 7A1 0101
Estrogen receptor0102
Substance-K receptor0404
Sodium-dependent noradrenaline transporter 0819
Thromboxane-A synthase 0202
Histamine H2 receptor0404
Gonadotropin-releasing hormone receptor0112
Sodium-dependent serotonin transporter0404
Type-1 angiotensin II receptor0101
Delta-type opioid receptor0404
Cytochrome P450 4F20101
Sodium-dependent dopamine transporter 0404
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Replicase polyprotein 1ab0101
CAAX prenyl protease 2 isoform 20001
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
Chain A, Retinoic acid receptor RXR-alpha0011
Chain A, Peroxisome proliferator-activated receptor gamma0011
neuropeptide S receptor isoform A2002
Aldehyde dehydrogenase, mitochondrial0011
ClpP1001
Cytochrome P450 1A10101
Cytochrome P450 1A2 0202
Myeloperoxidase0101
Cholinesterase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0213
Acetylcholinesterase0303
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0101
Mu-type opioid receptor0101
Nociceptin receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Cytochrome P450 1B10101
Palmitoleoyl-protein carboxylesterase NOTUM0101
Carboxylic ester hydrolase 0101
Histamine H3 receptor0101
Chain E, Fibrin beta chain0101
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog2002
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
TSHR protein1001
Apoptotic peptidase activating factor 10101
hypothetical protein, conserved2002
isocitrate dehydrogenase 1, partial1001
luciferase1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
Glutathione reductase0101
Glycoprotein hormones alpha chain2002
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Amine oxidase [flavin-containing] A0101
Cruzipain0101
Guanine nucleotide-binding protein G2002
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase2002
Seed linoleate 13S-lipoxygenase-10202
Seed linoleate 9S-lipoxygenase-30101
Peroxisome proliferator-activated receptor gamma0022
Peroxisome proliferator-activated receptor delta0011
Peroxisome proliferator-activated receptor alpha0011
serine/threonine-protein kinase PLK11001
Metabotropic glutamate receptor 60101
Acetylcholinesterase0101
5-hydroxytryptamine receptor 40404
Cytochrome P450 1A20101
Tyrosine-protein kinase Fyn0314
Muscarinic acetylcholine receptor M40404
Beta-1 adrenergic receptor0202
Muscarinic acetylcholine receptor M10404
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Androgen receptor0303
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M30202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
Aromatase0011
Alpha-1D adrenergic receptor0202
Substance-P receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0404
5-hydroxytryptamine receptor 1B0202
Indoleamine 2,3-dioxygenase 10101
Melanocortin receptor 40202
Melanocortin receptor 50202
Prostaglandin G/H synthase 20303
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
Melanocortin receptor 30202
Type-2 angiotensin II receptor0202
5-hydroxytryptamine receptor 60202
Cholinesterase0101
Indoleamine 2,3-dioxygenase 20101
Calcium release-activated calcium channel protein 10101
methionyl-tRNA synthetase, putative0101
Platelet-activating factor receptor0101
M-phase inducer phosphatase 10101
RAC-alpha serine/threonine-protein kinase0112
Chain A, Probable serine/threonine-protein kinase pknB0101
dopamine D1 receptor1001
WRN1001
nonstructural protein 10101
LANA0001
pyruvate kinase1001
phospholipase A2, group III0101
interferon gamma precursor0001
histone-lysine N-methyltransferase NSD2 isoform 10001
atrial natriuretic peptide receptor 2 precursor1001
tyrosine-protein kinase Yes2002
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
pyruvate kinase PKM isoform b1001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Proto-oncogene tyrosine-protein kinase ROS0101
Ornithine decarboxylase1001
Angiotensin-converting enzyme0202
Casein kinase II subunit alpha'0112
Multidrug resistance-associated protein 1 0101
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Tyrosine-protein kinase BTK0325
NEDD8-activating enzyme E1 regulatory subunit0011
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Nuclear receptor subfamily 3 group C member 3 0202
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
P2Y purinoceptor 120101
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Nuclear receptor corepressor 20101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
UDP-glucuronosyltransferase 1A90001
Sodium-dependent serotonin transporter0202
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
relaxin receptor 2 isoform 11001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0112
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Testosterone 17-beta-dehydrogenase 30101
Dynamin-like 120 kDa protein, mitochondrial0011
Putative nucleoside diphosphate kinase0011
Tyrosine-protein kinase JAK20202
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Tyrosine-protein kinase ABL10011
High affinity nerve growth factor receptor0011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Tyrosine-protein kinase Lck0112
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0101
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0112
Tyrosine-protein kinase Lyn0112
Proto-oncogene tyrosine-protein kinase receptor Ret0112
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0112
Tyrosine-protein kinase Fgr0101
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Proto-oncogene tyrosine-protein kinase Src0112
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Receptor tyrosine-protein kinase erbB-30101
Multifunctional protein ADE20011
Nucleoside diphosphate kinase B0011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10213
G1/S-specific cyclin-E10101
Cyclin-dependent kinase 20112
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20112
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30213
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
TGF-beta receptor type-20011
Tyrosine-protein kinase CSK0112
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0112
Tyrosine-protein kinase TXK0112
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0112
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0112
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Tyrosine-protein kinase Blk0112
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Cytoplasmic tyrosine-protein kinase BMX0213
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Tyrosine-protein kinase JAK30112
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10012
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C delta type0011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Tyrosine-protein kinase ITK/TSK0112
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60112
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40112
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10112
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
MAP kinase-activated protein kinase 30011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Sigma intracellular receptor 20101
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10011
Nuclear receptor subfamily 4 group A member 30101
Mitogen-activated protein kinase kinase kinase kinase 10011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Peroxiredoxin-like 2A0101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
Phenylalanine--tRNA ligase beta subunit0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20012
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Muscarinic acetylcholine receptor M10012
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0001
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Muscarinic acetylcholine receptor M50012
Sigma non-opioid intracellular receptor 10303
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Endolysin0011
Sulfotransferase 1A1 0001
Cannabinoid receptor 10101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase0202
Carbonic anhydrase 0101
Carbonic anhydrase 30202
Carbonic anhydrase0101
Carbonic anhydrase 130101
Carbonic anhydrase 5B, mitochondrial0202
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
Sterol 14-alpha-demethylase0022
14-alpha sterol demethylase 0022
14-alpha sterol demethylase 0022
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0213
dual specificity protein phosphatase 30101
low molecular weight phosphotyrosine protein phosphatase isoform c0101
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 10101
Dihydrofolate reductase0202
Dihydrofolate reductase 0101
Estrogen receptor0011
Beta-hexosaminidase subunit alpha0102
Beta-hexosaminidase subunit beta0101
Dihydrofolate reductase0214
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0202
Substance-K receptor0101
Dihydrofolate reductase0101
Low molecular weight phosphotyrosine protein phosphatase0101
Dipeptidyl peptidase 40101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trace amine-associated receptor 50011
Estrogen receptor beta0011
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
Dihydrofolate reductase0101
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
thyrotropin-releasing hormone receptor1001
caspase-1 isoform alpha precursor1001
Riboflavin-binding protein0112
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Caspase-71001
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit beta-10001
Tyrosinase0101
NAD(P)H dehydrogenase [quinone] 10001
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
cystic fibrosis transmembrane conductance regulator0101
C-8 sterol isomerase0101
Squalene monooxygenase 0101
Squalene monooxygenase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
HLA class I histocompatibility antigen, A alpha chain 0011
Solute carrier family 15 member 10101
Valacyclovir hydrolase0001
Chain A, Arginase 10101
Large neutral amino acids transporter small subunit 10101
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Cholesterol 24-hydroxylase0213
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
PTK2B protein tyrosine kinase 2 beta0101
serine/threonine-protein kinase 33 isoform a0011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]