Page last updated: 2024-10-25

clioquinol and Fusariosis

clioquinol has been researched along with Fusariosis in 1 studies

Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

Fusariosis: OPPORTUNISTIC INFECTIONS with the soil fungus FUSARIUM. Typically the infection is limited to the nail plate (ONYCHOMYCOSIS). The infection can however become systemic especially in an IMMUNOCOMPROMISED HOST (e.g., NEUTROPENIA) and results in cutaneous and subcutaneous lesions, fever, KERATITIS, and pulmonary infections.

Research Excerpts

ExcerptRelevanceReference
"This study proposes an association of clioquinol, an inhibitor of fungal cells with antifungal drugs prescribed to combat fusariosis in humans."3.96Synergistic association of clioquinol with antifungal drugs against biofilm forms of clinical Fusarium isolates. ( de Andrade, SF; de Chaves, MA; Fernanda Andrzejewski Kaminski, T; Ferreira do Amaral, T; Flavio Souza de Oliveira, L; Fuentefria, AM; Monteiro da Silva Rodrigues Coutinho, N; Teixeira, ML, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
de Chaves, MA1
Ferreira do Amaral, T1
Monteiro da Silva Rodrigues Coutinho, N1
Fernanda Andrzejewski Kaminski, T1
Teixeira, ML1
Flavio Souza de Oliveira, L1
de Andrade, SF1
Fuentefria, AM1

Other Studies

1 other study available for clioquinol and Fusariosis

ArticleYear
Synergistic association of clioquinol with antifungal drugs against biofilm forms of clinical Fusarium isolates.
    Mycoses, 2020, Volume: 63, Issue:10

    Topics: Antifungal Agents; Biofilms; Ciclopirox; Clioquinol; Drug Combinations; Drug Synergism; Fusariosis;

2020