Page last updated: 2024-11-01

ofloxacin and Salpingitis

ofloxacin has been researched along with Salpingitis in 8 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Salpingitis: Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)

Research Excerpts

ExcerptRelevanceReference
" Patients identified with laparoscopic findings of salpingitis were treated with 400 mg of intravenous ofloxacin every 12 hours followed by 400 mg of oral ofloxacin every 12 hours for 10 to 14 days."9.09Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis). ( Kahn, J; Peipert, JF; Rielly-Gauvin, K; Sweet, RL; Walker, CK, 1999)
"The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis."9.07A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991)
"We attempted to define the microbiologic characteristics of acute salpingitis in women presenting to an urban emergency department with pelvic inflammatory disease and to determine the effectiveness of ofloxacin in treating this disease."7.68Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin. ( Brockwell, NJ; Dalton, HP; Soper, DE, 1992)
" Patients identified with laparoscopic findings of salpingitis were treated with 400 mg of intravenous ofloxacin every 12 hours followed by 400 mg of oral ofloxacin every 12 hours for 10 to 14 days."5.09Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis). ( Kahn, J; Peipert, JF; Rielly-Gauvin, K; Sweet, RL; Walker, CK, 1999)
"The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis."5.07A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991)
"We attempted to define the microbiologic characteristics of acute salpingitis in women presenting to an urban emergency department with pelvic inflammatory disease and to determine the effectiveness of ofloxacin in treating this disease."3.68Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin. ( Brockwell, NJ; Dalton, HP; Soper, DE, 1992)
"30."2.68[Comparative study of ofloxacin+amoxicillin-clavulanic acid versus doxycycline+amoxicillin-clavulanic acid combination in the treatment of pelvic Chlamydia trachomatis infections]. ( Badonnel, Y; Dailloux, M; Judlin, P; Koebele, A; Landes, P; Pavis, A; van Walleghen, E; Zaccabri, A, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Judlin, P1
Koebele, A1
Zaccabri, A1
van Walleghen, E1
Pavis, A1
Badonnel, Y1
Dailloux, M1
Landes, P1
Verhoest, P2
Fernandez, H1
Henry-Suchet, J2
Orfila, J3
Boulanger, JC2
Tannous, W1
Peipert, JF1
Sweet, RL1
Walker, CK1
Kahn, J1
Rielly-Gauvin, K1
Soper, DE1
Brockwell, NJ1
Dalton, HP1
Haider, F2
Wendel, GD1
Cox, SM1
Bawdon, RE1
Theriot, SK1
Heard, MC1
Nobles, BJ1
Vitse, M1

Trials

7 trials available for ofloxacin and Salpingitis

ArticleYear
[Comparative study of ofloxacin+amoxicillin-clavulanic acid versus doxycycline+amoxicillin-clavulanic acid combination in the treatment of pelvic Chlamydia trachomatis infections].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1995, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Chlamydia Infections;

1995
[A new therapeutic strategy using a ofloxacin-amoxicillin-clavulanic acid combination in the treatment of upper gynecologic infections. Apropos of 123 cases].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1994, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibito

1994
[Medical management of chronic Chlamydia trachomatis salpingitis resistant to usual antibiotics. Use of ofloxacin alone or combined with other anti-chlamydia antibiotics].
    Contraception, fertilite, sexualite (1992), 1993, Volume: 21, Issue:9

    Topics: Adult; Chlamydia Infections; Chlamydia trachomatis; Chronic Disease; Doxycycline; Drug Resistance, M

1993
Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis).
    Infectious diseases in obstetrics and gynecology, 1999, Volume: 7, Issue:3

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; Dru

1999
[Can various antibiotics be combined for treating salpingitis?].
    Revue francaise de gynecologie et d'obstetrique, 1992, Volume: 87, Issue:3

    Topics: Doxycycline; Drug Combinations; Female; Humans; Imipenem; Ofloxacin; Salpingitis

1992
A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis.
    American journal of obstetrics and gynecology, 1991, Volume: 164, Issue:5 Pt 2

    Topics: Acute Disease; Adult; Ambulatory Care; Cefoxitin; Chi-Square Distribution; Chlamydia Infections; Chl

1991
[Proposal for a new therapeutic strategy in high genital infections].
    Revue francaise de gynecologie et d'obstetrique, 1989, Volume: 84, Issue:12

    Topics: Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Chlamydia Infections;

1989

Other Studies

1 other study available for ofloxacin and Salpingitis

ArticleYear
Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin.
    American journal of obstetrics and gynecology, 1992, Volume: 167, Issue:3

    Topics: Acute Disease; Adult; Chlamydia Infections; Emergency Medical Services; Female; Follow-Up Studies; G

1992