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metronidazole and Salpingitis

metronidazole has been researched along with Salpingitis in 19 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Salpingitis: Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)

Research Excerpts

ExcerptRelevanceReference
"110 patients suffering from laparoscopical verified salpingitis and desire for a baby, were treated with tetracycline (oxytetracycline or doxycycline; TC)/metronidazole (n = 67), augmentan (n = 22) or cipropfloxacin/metronidazole (n = 21)."9.07[Treatment of acute salpingitis with tetracycline/metronidazole with or without additional balneotherapy, Augmentin or ciprofloxacin/metronidazole: a second-look laparoscopy study]. ( Barten, G; Gerber, B; Splitt, G; Wilken, H; Zacharias, K, 1992)
"The best way of treating pelvic inflammatory disease (PID) is not known."5.27Treating pelvic inflammatory disease with doxycycline and metronidazole or penicillin and metronidazole. ( Aine, R; Heinonen, PK; Lehtinen, M; Miettinen, A; Paavonen, J; Punnonen, R; Teisala, K, 1986)
"110 patients suffering from laparoscopical verified salpingitis and desire for a baby, were treated with tetracycline (oxytetracycline or doxycycline; TC)/metronidazole (n = 67), augmentan (n = 22) or cipropfloxacin/metronidazole (n = 21)."5.07[Treatment of acute salpingitis with tetracycline/metronidazole with or without additional balneotherapy, Augmentin or ciprofloxacin/metronidazole: a second-look laparoscopy study]. ( Barten, G; Gerber, B; Splitt, G; Wilken, H; Zacharias, K, 1992)
"An open randomised comparative trial of the efficacy and safety of Augmentin as against the triple therapy of penicillin-gentamicin-metronidazole in acute salpingitis was conducted in forty women admitted to hospital."5.06[Treatment of acute non-chlamydial salpingitis. Study of the efficacy and tolerance of a single-therapy antibiotic: Augmentin]. ( Barrat, J; Marpeau, L; Pigné, A; Tessier, F; Tison, E, 1988)
"mulieris in Turkish women with bacterial vaginosis, vulvo-vaginal abscesses, endometritis or salpingitis."1.33Mobiluncus species in gynaecological and obstetric infections: antimicrobial resistance and prevalence in a Turkish population. ( Bahar, H; Kocazeybek, B; Oçer, F; Torun, MM, 2005)
"The best way of treating pelvic inflammatory disease (PID) is not known."1.27Treating pelvic inflammatory disease with doxycycline and metronidazole or penicillin and metronidazole. ( Aine, R; Heinonen, PK; Lehtinen, M; Miettinen, A; Paavonen, J; Punnonen, R; Teisala, K, 1986)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's3 (15.79)18.2507
2000's2 (10.53)29.6817
2010's1 (5.26)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Lam, R1
Jamidar, PA1
Aslanian, HR1
Muniraj, T1
Kim, YS1
Kwon, H1
Choi, DH1
Helenius, I1
Takala, T1
Ristkari, S1
Järvi, K1
Mokka, R1
Bahar, H1
Torun, MM1
Oçer, F1
Kocazeybek, B1
Oyarzún, E1
Gómez, R1
Montiel, F1
Gerber, B1
Wilken, H1
Zacharias, K1
Barten, G1
Splitt, G1
Teisala, K3
Heinonen, PK3
Buisson, P1
Mulard, C1
Baudet, J1
Bernard, P1
Mares, P1
Montero, M1
Lerat, M1
Quereux, C1
Santarelli, J1
Valette, C1
Punnonen, R2
Aine, R2
Lehtinen, M2
Miettinen, A2
Paavonen, J2
Tison, E1
Marpeau, L1
Pigné, A1
Tessier, F1
Barrat, J1
Skjeldestad, FE1
Dalen, A1
Koinzer, G1
Walter, S1
Peschke, KH1
Wecke, WD1
Ledger, WJ1
Grönroos, P1
Gaudin, G1
Monif, GR1
Sebek, V1
Willocx, RR1
Pejtsik, B1
Tóth, E1

Reviews

1 review available for metronidazole and Salpingitis

ArticleYear
[Bacterial vaginosis II. Related pathology and therapy].
    Revista chilena de obstetricia y ginecologia, 1995, Volume: 60, Issue:2

    Topics: Anti-Bacterial Agents; Chorioamnionitis; Clindamycin; Endometritis; Female; Humans; Metronidazole; O

1995

Trials

4 trials available for metronidazole and Salpingitis

ArticleYear
[Treatment of acute salpingitis with tetracycline/metronidazole with or without additional balneotherapy, Augmentin or ciprofloxacin/metronidazole: a second-look laparoscopy study].
    Geburtshilfe und Frauenheilkunde, 1992, Volume: 52, Issue:3

    Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Balneology; Clavulanic Acids; Com

1992
[Treatment of upper genital infections in women. Multicenter study of the comparative efficacy and tolerance of an amoxicillin-clavulanic acid combination and of a triple antibiotic combination].
    Revue francaise de gynecologie et d'obstetrique, 1989, Volume: 84, Issue:10

    Topics: Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acids; Dru

1989
[Treatment of acute non-chlamydial salpingitis. Study of the efficacy and tolerance of a single-therapy antibiotic: Augmentin].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1988, Volume: 17, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-B

1988
[Comparative clinical study between Rocephin (Roche) and doxycycline, amoxycillin, erythromycin and amoxycillin + metronidazole combination in gynecology].
    Gynakologische Rundschau, 1985, Volume: 25, Issue:2

    Topics: Abscess; Adult; Aged; Amoxicillin; Breast Diseases; Cefotaxime; Ceftriaxone; Clinical Trials as Topi

1985

Other Studies

14 other studies available for metronidazole and Salpingitis

ArticleYear
Fitz-Hugh-Curtis Syndrome Presenting as Acute Abdomen.
    The American journal of medicine, 2020, Volume: 133, Issue:10

    Topics: Abdomen, Acute; Anti-Bacterial Agents; Cefoxitin; Doxycycline; Exudates and Transudates; Female; Hep

2020
Ruptured pyosalpinx following a fetal reduction procedure.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2012, Volume: 119, Issue:1

    Topics: Abdominal Pain; Adult; Anti-Bacterial Agents; C-Reactive Protein; Cephalosporins; Fallopian Tubes; F

2012
[Actinomycosis--a rare cause of purulent peritonitis in a woman in fertile age].
    Duodecim; laaketieteellinen aikakauskirja, 2001, Volume: 117, Issue:7

    Topics: Actinomyces; Actinomycosis; Adult; Anti-Bacterial Agents; Cefuroxime; Cephalosporins; Doxycycline; D

2001
Mobiluncus species in gynaecological and obstetric infections: antimicrobial resistance and prevalence in a Turkish population.
    International journal of antimicrobial agents, 2005, Volume: 25, Issue:3

    Topics: Abscess; Actinomycetales Infections; Anaerobiosis; Anti-Bacterial Agents; Cross-Sectional Studies; C

2005
C-reactive protein in assessing antimicrobial treatment of acute pelvic inflammatory disease.
    The Journal of reproductive medicine, 1990, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Biopsy; C-Reactive Protein; Ciprofloxacin; Doxycycline; Drug Therapy, Combination

1990
Treating pelvic inflammatory disease with doxycycline and metronidazole or penicillin and metronidazole.
    Genitourinary medicine, 1986, Volume: 62, Issue:4

    Topics: Adult; Chlamydia trachomatis; Doxycycline; Drug Therapy, Combination; Endometritis; Female; Humans;

1986
Chlamydia trachomatis: is it possible to reduce the number of infections after abortions?
    Scandinavian journal of primary health care, 1988, Volume: 6, Issue:2

    Topics: Abortion, Induced; Adult; Cervix Uteri; Chlamydia Infections; Chlamydia trachomatis; Drug Therapy, C

1988
[Prevention of infection with metronidazole in abortion induced by PGF2 alpha].
    Zentralblatt fur Gynakologie, 1986, Volume: 108, Issue:3

    Topics: Abortion, Induced; Adolescent; Adult; Dinoprost; Endometritis; Female; Humans; Metronidazole; Pelvic

1986
Aminoglycosides in gynecologic infections.
    The American journal of medicine, 1986, Jun-30, Volume: 80, Issue:6B

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Clindamycin;

1986
Haemophilus influenzae causes purulent salpingitis.
    American journal of obstetrics and gynecology, 1985, Feb-01, Volume: 151, Issue:3

    Topics: Adult; Doxycycline; Fallopian Tubes; Female; Haemophilus Infections; Haemophilus influenzae; Humans;

1985
Choice of antibiotics and length of therapy in the treatment of acute salpingitis.
    The American journal of medicine, 1985, Jun-28, Volume: 78, Issue:6B

    Topics: Acute Disease; Anti-Bacterial Agents; Cefoxitin; Chlamydia Infections; Chlamydia trachomatis; Doxycy

1985
[Trichomonas pyosalpinx].
    Zentralblatt fur Gynakologie, 1972, Nov-18, Volume: 94, Issue:46

    Topics: Adult; Female; Humans; Metronidazole; Postoperative Care; Salpingitis; Trichomonas vaginalis; Tricho

1972
'Epidemiological' treatment in venereal diseases other than syphilis.
    The British journal of venereal diseases, 1973, Volume: 49, Issue:2

    Topics: Epidemiologic Methods; Female; Gonorrhea; Humans; Imidazoles; Male; Methods; Metronidazole; Morpholi

1973
[The role of Trichomonas urogenitalis in the development of adnexitis and its treatment].
    Zeitschrift fur Geburtshilfe und Gynakologie, 1969, Volume: 170, Issue:1

    Topics: Adolescent; Cystitis; Female; Humans; Metronidazole; Oophoritis; Pelvic Inflammatory Disease; Salpin

1969