Conditions > Encephalitis, Inclusion Body, Measles
Page last updated: 2024-09-28

Encephalitis, Inclusion Body, Measles

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Synonyms(11)

Synonym
Measles Inclusion Body Encephalitis
Inclusion Body Encephalitis, Measles
SSPE
Van Bogaert's Leukoencephalitis
Encephalitis, Inclusion Body, Measles
Subacute Sclerosing Panencephalitis
Leukoencephalitis, Van Bogaert's
Leukoencephalitis, Subacute Sclerosing
Sclerosing Leukoencephalitis, Subacute
Sclerosing Panencephalitis, Subacute
Panencephalitis, Subacute Sclerosing

Research Excerpts

Overview

ExcerptReference
"SSPE is characterised by progressive mental deterioration, myoclonic and similar motor disorders and final severe comatose states, increase of immunoglobuline G in the CSF, strongly elevated antibody titers to measles virus in serum and CSF and typical periodic K-complexes in the EEG."( Barocka, A; Flügel, KA; Woelk, H, 1979)
"Subacute sclerosing panencephalitis is a central nervous system degenerative disease that rapidly progresses to death in most untreated cases."( DuRant, RH; Dyken, PR; Swift, AV, 1982)
"Subacute sclerosing panencephalitis is a rare progressive inflammatory disease of the central nervous system caused by a persistent aberrant measles virus infection."( Anlar, B; Coskun, M; Haspolat, S; Köse, G; Yegin, O, 2001)
"Subacute sclerosing panencephalitis is an almost universally fatal late complication of measles infection for which there is no established treatment."( Beeching, NJ; Hart, CA; Humphrey, P; Malucci, C; Solomon, T; Vinjamuri, S, 2002)
"Subacute sclerosing panencephalitis is caused by persistent brain infection of mutated measles virus, showing inflammation, neuronal loss, and demyelination."( Arai, N; Hayashi, M; Katayama, K; Morimatsu, Y; Satoh, J; Suzuki, H; Tamagawa, K, 2002)
"Subacute sclerosing panencephalitis is progressive, fatal encephalitis caused by a persistent defective measles virus in the central nervous system."( Cakmakci, H; Dirik, E; Iscan, A; Kurul, S, 2004)
"Subacute sclerosing panencephalitis is a neurodegenerative disease with a poor prognosis."( Aydin, OF; Gürer, YK; Senbil, N, 2006)
"The diagnosis of SSPE is often difficult in the early stages."( Garg, RK, 2008)
"Subacute sclerosing panencephalitis is a devastating progressive degenerative disease of the nervous system presumably caused by a persistent measles virus."( Abou-Khalil, BW; Becker, D; Patel, A; Pina-Garza, JE, 2009)
"The onset of SSPE is insidious, and psychiatric manifestations are prominent."( Gutierrez, J; Issacson, RS; Koppel, BS, 2010)
"SSPE is a chronic encephalitis characterized by a history of measles infection and a progressive disease of the central nervous system that still occurs frequently in countries with insufficient measles immunization."( Anlar, B; Colpak, AI; Erdener, SE; Kansu, T; Ozgen, B, 2012)
"Subacute sclerosing panencephalitis is a rare disease of central nervous system caused by defective measles virus."( Aksoy, A; Kadayifcilar, S; Ozer, PA; Ozkan, M; Sekeroglu, HT; Yuksel, D, 2014)
"Although SSPE is a progressive disease of the neuronal system, and typically leads to death in approximately 2-3 years, the neurological prognosis of our case was good."( Hara, M; Ishibashi, M; Kaida, H; Kurata, S; Matsuishi, T; Nagamitsu, S; Ohya, T; Shibuya, I; Yamashita, Y, 2014)
"Adult-onset SSPE is very rare and often presents with atypical features."( Gokoglu, A; Gozdas, HT, 2019)

Context

ExcerptReference
"However, SSPE has reappeared in internationally adopted children and in refugee children emigrating from developing or war torn countries lacking effective measles immunization programs."( Risk, WS, 2003)
"The incidence of SSPE has substantially declined after the introduction of an effective vaccine."( Castellano-Chiodo, D; Iacono, O; Pavone, P; Praticò, AD; Saporito, M, 2011)

Treatment

ExcerptReference
"Six patients with subacute sclerosing panencephalitis were treated with the antiviral agent inosiplex."( Abramsky, O; Brenner, T; Silverberg, R, 1979)
"The pathogenesis of subacute sclerosing leukoencephalitis, similarities of laboratory findings to multiple sclerosis, and problems of treatment are discussed."( Glasner, H; Kirsch, W, 1975)
"We treated 22 patients with subacute sclerosing panencephalitis (SSPE) with intraventricular alpha-interferon (IFN) and inosiplex PO and followed them for 2 to 54 months."( Anlar, B; Aysun, S; Gucuyener, K; Gurcay, O; Oktem, F; Renda, Y; Ustacelebi, S; Yalaz, K, 1992)
"A total of 151 cases of subacute sclerosing panencephalitis (SSPE), comprising 89 cases treated with MND-19 (Inosiplex) and 62 untreated cases, were retrospectively investigated as to background characteristics, survival rate and clinical course in order to compare the findings in the 2 groups of cases."( Arima, M; Ebina, T; Fukuyama, Y; Kamoshita, S; Matsumoto, S; Nihei, K; Ohtahara, S; Sato, T; Ueda, S; Yabuuchi, H, 1987)
"A 22-year-old female patient with subacute sclerosing panencephalitis was treated for three months with interferon by the intraventricular route and methisoprinol (inosiplex) by mouth."( Blumbergs, PC; Harbord, MG; Hicks, EP; Jones, T, 1988)
"3 groups of patients, who suffered on SSPE (without treatment, with isoprinosine therapy, combined treatment with propionibacterium granulosum and isoprinosine) are compared."( Iwińska, B; Jeliaszewicź, J; Kulczycki, J; Plachcińska, J; Pulverer, G; Sobczyk, W; Szmigielskí, S; Vainiene, M, 1989)
"Longitudinal studies performed in 6 SSPE patients during isoprinosine therapy revealed a time-dependent decrement of the %s of E- and EA-RFC in CSF."( Cianchetti, C; Ennas, MG; Manconi, PE; Marrosu, G; Marrosu, MG; Murru, MR; Tondi, M, 1983)
"Recent effective treatments for subacute sclerosing panencephalitis (SSPE) are oral inosiplex and intrathecal interferon therapy."( Horiguchi, Y; Ohya, T, 1995)
"A 10-year-old boy with subacute sclerosing panencephalitis was treated with intravenous gamma-globulin and inosiplex and followed for 18 months."( Gürer, YK; Kükner, S; Sarica, B, 1996)
"We treated 22 patients with subacute sclerosing panencephalitis (SSPE) with intraventricular alpha-interferon (alpha-IFN) and oral inosiplex between 1986 and 1991."( Anlar, B; Köse, G; Oktem, F; Yalaz, K, 1997)
"We treated seven patients with subacute sclerosing panencephalitis with beta-interferon and oral inosiplex for 2 to 15 months."( Anlar, B; Köse, G; Saygi, S; Yalaz, K, 1998)
"Two patients with subacute sclerosing panencephalitis (SSPE) were treated safely and effectively with high doses of intravenous ribavirin combined with intraventricular alpha interferon."( Hosoya, M; Miike, T; Mori, S; Shigeta, S; Shiraishi, S; Suzuki, H; Tomoda, A, 2001)
"We compared patients with subacute sclerosing panencephalitis who received treatment according to our protocol for at least 6 months (19 patients) with the patients who could not receive any treatment (13 patients)."( Aydin, OF; Gürer, YK; Kuyucu, N; Senbil, N, 2003)
"A survey was made on 10 patients with subacute sclerosing panencephalitis (SSPE) during the last four years from the viewpoint of clinical safety of ribavirin therapy in Japan."( Hamada, A; Hosoya, M; Miike, T; Nomura, K; Shiraishi, S; Tomoda, A, 2003)
"Ten patients with SSPE were surveyed during the last 4 years from the viewpoint of clinical safety for use of ribavirin therapy."( Fukushima, A; Hamada, A; Hosoya, M; Kato, Z; Kimura, H; Miike, T; Mori, K; Nezu, A; Nihei, K; Nishio, H; Nomura, K; Ohmura, T; Sawaishi, Y; Shiraishi, S; Takashima, H; Tohda, Y; Tomoda, A, 2003)
"Five patients with subacute sclerosing panencephalitis (SSPE) were treated with ribavirin by intraventricular administration."( Hosoya, M; Kimura, H; Mori, K; Mori, S; Sawaishi, Y; Shigeta, S; Suzuki, H; Tomoda, A, 2004)
"We treated a 12-year-old boy with subacute sclerosing panencephalitis who presented with acute encephalopathy and myoclonus."( Abou-Khalil, BW; Becker, D; Patel, A; Pina-Garza, JE, 2009)
"We treated three patients with subacute sclerosing panencephalitis with intraventricular interferon-alpha and oral inosiplex, and followed their clinical courses."( Arai, A; Komaki, H; Nakagawa, E; Nonoda, Y; Sakuma, H; Sasaki, M; Sato, K; Sugai, K, 2009)
"We describe a 15-year-old girl with subacute sclerosing panencephalitis (SSPE) in stage II who was treated with isoprinosine, intraventricular interferon alpha (IFN-α), and ribavirin for 3 years."( Hara, M; Ishibashi, M; Kaida, H; Kurata, S; Matsuishi, T; Nagamitsu, S; Ohya, T; Shibuya, I; Yamashita, Y, 2014)
"Three patients with new-onset SSPE were treated with RBV using a subcutaneous continuous infusion pump."( Abe, Y; Hashimoto, K; Hosoya, M; Kanno, S; Kawasaki, Y; Maeda, H; Miyazaki, K; Sato, M; Suyama, K; Watanabe, M, 2019)

Research

Studies (311)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990161 (51.77)23.3326
1990's46 (14.79)12.5806
2000's66 (21.22)18.1394
2010's29 (9.32)28.8240
2020's9 (2.89)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
adenine0low10
bromide0low10
carbon monoxide0low10
choline0low60
salicylic acid0low10
creatine0low30
cytosine0low10
lactic acid0low10
formaldehyde0low40
glycine0low10
dihydroxyphenylalanine0low10
methanol0low10
inositol0low50
nitrates0low10
nitrites0low10
quinolinic acid0low10
thiamine0low10
uracil0low10
urea0low10
homovanillic acid0low10
phenytoin0low20
hydroxyindoleacetic acid0low10
amantadine0low130
azathioprine0low40
metrizoate0low10
carbamazepine0low90
chlorambucil0low20
cimetidine0medium21
clonazepam0low20
diazepam0low80
valproic acid0low40
ether0low10
glutaral0low10
isoniazid0low10
midazolam0low10
apnea0low10
phenobarbital0low10
piracetam0low10
primidone0low10
rimantadine0low10
trihexyphenidyl0low10
vigabatrin0low10
prednisolone0low40
thymidine0low20
floxuridine0low10
dextroamphetamine0low10
prednisone0low20
azauridine0low10
idoxuridine0low30
serine0low10
aspartic acid0low70
sucrose0low20
uridine0low30
bromodeoxyuridine0low20
levodopa0low20
tyrosine0low30
leucine0low10
cycloheximide0low10
chloroform0low10
cytarabine0low10
trifluridine0low10
histidine0low10
valine0low20
tryptophan0low20
isoleucine0low10
arginine0low10
phencyclidine0low10
fluocortolone0low20
thiamine pyrophosphate0low10
pyrazines0low10
cuprizone0low10
alpha-aminopyridine0low10
malondialdehyde0low10
d-alpha tocopherol0low10
digoxigenin0low10
fucose0low20
vidarabine0low20
gold0low10
fluorine0low10
galactose0low20
trolamine salicylate0low20
levamisole0low10
phenyl acetate0low10
cetylpyridinium chloride anhydrous0low10
transferrin0low20
ribavirin0medium231
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid0low10
fomesafen0low10
flupirtine0low10
fluorodopa f 180low10
lamivudine0medium21
trazodone hydrochloride0low10
n-acetylaspartic acid0low70
fluorodeoxyglucose f180medium91
1-hexadecyl-2-acetyl-glycero-3-phosphocholine0low10
deoxyglucose0low40
methotrexate0low50
biotin0low20
cortisone0low10
lanosterol0low10
desmosterol0low10
retinol0low20
mycophenolic acid0low10
dactinomycin0low30
favipiravir0low10
methisazone0low10
D-fructopyranose0low10
digoxin0low20
pica0low10
ovalbumin0low10
sodium dodecyl sulfate0low10
myelin basic protein0low110
beta carotene0low20
amphotericin b0low10
4-hydroxy-2-nonenal0low10
levetiracetam0low10
topiramate0low10
lysophosphatidylcholines0low10
cytochalasin b0low10
cesium0low10
cysteine0low10
dolichols0low20
sq-233770low10
sepharose0low20
acid phosphatase0low20
cellulose0low10
phosphatidylcholines0low60
thimerosal0low10
ubiquinone0low20
glycolipids0low30
galactocerebroside0low10
ascorbic acid0low30
thymic factor, circulating0low10
agar0low40
hyaluronoglucosaminidase0low10
acyclovir0low10
guanine0low10
guanosine0low10
inosine0medium318
neopterin0low20
rifampin0low20
olanzapine0low10
8-hydroxyguanosine0low10
aprepitant0medium11
inosine pranobex0medium9414
eye0low30
carbidopa0low10
concanavalin a0low30
technetium tc 99m bicisate0low10
phosphorus radioisotopes0low10

Protein Targets (1,108)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE230023
Chain A, Cruzipain8008
regulator of G-protein signaling 4140014
Platelet-activating factor receptor0202
Inositol monophosphatase 14004
hypoxia-inducible factor 1 alpha subunit100010
RAR-related orphan receptor gamma300030
GLI family zinc finger 3300030
AR protein450045
aldehyde dehydrogenase 1 family, member A1260026
retinoic acid nuclear receptor alpha variant 1300030
retinoid X nuclear receptor alpha230023
estrogen nuclear receptor alpha500050
peroxisome proliferator-activated receptor delta190019
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a220022
activating transcription factor 6130013
v-jun sarcoma virus 17 oncogene homolog (avian)190019
Histone H2A.x170017
thyroid hormone receptor beta isoform a110011
heat shock protein beta-1120012
nuclear factor erythroid 2-related factor 2 isoform 1300030
lamin isoform A-delta10340034
Voltage-dependent calcium channel gamma-2 subunit200020
Glutamate receptor 2212023
Microtubule-associated protein tau170017
vitamin D3 receptor isoform VDRA160016
Transient receptor potential cation channel subfamily A member 10011
Chain A, Beta-lactamase4004
GLS protein170017
euchromatic histone-lysine N-methyltransferase 2420042
geminin440044
Polyphenol oxidase 20407
Acetylcholinesterase0404
Prostaglandin G/H synthase 10202
Sodium-dependent dopamine transporter0112
Prostaglandin G/H synthase 20303
Xanthine dehydrogenase/oxidase0202
Dehydrogenase/reductase SDR family member 90101
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein120012
Chain B, HADH2 protein120012
Chain A, ATP-DEPENDENT DNA HELICASE Q17007
Chain A, Ferritin light chain9009
Thymidine kinase 0405
thioredoxin reductase290029
phosphopantetheinyl transferase170017
TDP1 protein400040
Smad39009
thyroid stimulating hormone receptor180018
EWS/FLI fusion protein160016
arylsulfatase A190019
Bloom syndrome protein isoform 1170017
hemoglobin subunit beta2002
atrial natriuretic peptide receptor 1 precursor7007
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
Solute carrier family 22 member 1 0408
ATP-binding cassette sub-family C member 3024024
Multidrug resistance-associated protein 4024025
Solute carrier family 22 member 60304
Bile salt export pump0909
Bile salt export pump035035
Purine nucleoside phosphorylase0305
Thymidine kinase, cytosolic0509
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0606
Cytochrome P450 2J20404
Disintegrin and metalloproteinase domain-containing protein 173003
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60204
Thymidine kinase 0101
Solute carrier family 22 member 80306
Canalicular multispecific organic anion transporter 1021021
Thymidine kinase0203
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
nuclear receptor subfamily 1, group I, member 3290029
cytochrome P450 family 3 subfamily A polypeptide 4170017
glucocorticoid receptor [Homo sapiens]280028
estrogen-related nuclear receptor alpha380038
pregnane X nuclear receptor270027
nuclear factor erythroid 2-related factor 2 isoform 2220022
importin subunit beta-1 isoform 16006
snurportin-16006
tumor susceptibility gene 101 protein2002
GTP-binding nuclear protein Ran isoform 13003
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
TAR DNA-binding protein 43110011
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 5160016
Ataxin-2200020
thyroid stimulating hormone receptor110011
thyroid hormone receptor beta isoform 2280028
Heat shock protein HSP 90-alpha0011
Botulinum neurotoxin type A 0101
Neutrophil cytosol factor 10101
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0114
Kappa-type opioid receptor0011
Phosphatidylinositol 4-kinase alpha0101
Mu-type opioid receptor0112
Tyrosine-protein kinase 0011
Phosphatidylinositol 4-kinase type 2-beta0101
Phosphatidylinositol 4-kinase type 2-alpha0101
Phosphatidylinositol 4-kinase beta0101
acetylcholinesterase110011
NFKB1 protein, partial6006
signal transducer and activator of transcription 6, interleukin-4 induced1001
putative alpha-glucosidase1001
peripheral myelin protein 22200020
histone acetyltransferase KAT2A isoform 1100010
Solute carrier family 22 member 20407
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Matrix protein 20123
Matrix protein 20235
Glutamate receptor ionotropic, NMDA 1 07112
Spike glycoprotein120214
Glutamate receptor ionotropic, NMDA 2A 07112
Glutamate receptor ionotropic, NMDA 2B08113
Glutamate receptor ionotropic, NMDA 2C07113
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, NMDA 2B0303
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 2D07112
Solute carrier family 22 member 10506
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B07112
Multidrug and toxin extrusion protein 10404
Solute carrier family 22 member 20506
Glutamate receptor ionotropic, NMDA 3A07112
ATP-dependent phosphofructokinase180018
interleukin 8150015
farnesoid X nuclear receptor170017
vitamin D (1,25- dihydroxyvitamin D3) receptor250025
tumor necrosis factor2103
Cytochrome P450 1A20202
Cytochrome P450 3A4010011
Cytochrome P450 2D60404
Cytochrome P450 2C190303
Nuclear receptor ROR-gamma131216
Potassium voltage-gated channel subfamily H member 20707
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20203
ATAD5 protein, partial130013
D(1A) dopamine receptor4004
neuropeptide S receptor isoform A4004
GALC protein3003
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)140014
progesterone receptor190019
G9009
cytochrome P450 2D69009
peroxisome proliferator activated receptor gamma230023
caspase-35005
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 9009
Cellular tumor antigen p53310031
Substance-P receptor0213
Neuromedin-K receptor0101
cGMP-dependent protein kinase 1 0011
Substance-P receptor0101
Inositol hexakisphosphate kinase 19009
cytochrome P450 2C9, partial9009
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
alpha-galactosidase7007
cytochrome P450 2C19 precursor4004
chromobox protein homolog 1250025
flap endonuclease 1150015
DNA polymerase iota isoform a (long)180018
muscarinic acetylcholine receptor M1130013
lethal factor (plasmid)110011
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, inducible0001
Cationic amino acid transporter 30101
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase8008
IDH1150015
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0202
Alpha-2B adrenergic receptor0213
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE100010
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 109017
Carbonic anhydrase 2010321
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0002
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0006
Carbonic anhydrase 40204
SMAD family member 28008
Fumarate hydratase6006
SMAD family member 38008
polyprotein6006
P532002
aryl hydrocarbon receptor110011
peripheral myelin protein 22 isoform 19009
cellular tumor antigen p53 isoform a8008
survival motor neuron protein isoform d180018
cytochrome P450 3A4 isoform 1130013
M-phase phosphoprotein 89009
muscleblind-like protein 1 isoform 14004
Gamma-aminobutyric acid receptor subunit pi137121
Gamma-aminobutyric acid receptor subunit beta-1137121
Gamma-aminobutyric acid receptor subunit delta137121
Gamma-aminobutyric acid receptor subunit gamma-2137222
Gamma-aminobutyric acid receptor subunit alpha-5137121
Gamma-aminobutyric acid receptor subunit alpha-3137121
Gamma-aminobutyric acid receptor subunit gamma-1137121
Gamma-aminobutyric acid receptor subunit alpha-2137121
Gamma-aminobutyric acid receptor subunit alpha-4137121
Gamma-aminobutyric acid receptor subunit gamma-3137121
Gamma-aminobutyric acid receptor subunit alpha-6137121
Gamma-aminobutyric acid receptor subunit alpha-1137222
Gamma-aminobutyric acid receptor subunit beta-3137121
Gamma-aminobutyric acid receptor subunit beta-2137222
GABA theta subunit137121
Gamma-aminobutyric acid receptor subunit epsilon137121
Protein-arginine deiminase type-40404
glp-1 receptor, partial9009
Skn7p0001
apical membrane antigen 1, AMA14004
nonstructural protein 12002
67.9K protein170017
Janus kinase 2 (a protein tyrosine kinase)0101
urokinase-type plasminogen activator precursor100010
plasminogen precursor100010
urokinase plasminogen activator surface receptor precursor100010
Orotidine 5'-phosphate decarboxylase0101
Orotidine 5'-phosphate decarboxylase0101
Integrin beta-35005
Integrin alpha-IIb5005
Alpha-synuclein4318
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
core protein, partial0101
Solute carrier organic anion transporter family member 1B30709
Solute carrier organic anion transporter family member 1B10506
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, JmjC domain-containing histone demethylation protein 3A5005
nonstructural protein 10101
green fluorescent protein, partial0101
insulin-degrading enzyme isoform 10011
Streptavidin0011
Receptor-type tyrosine-protein phosphatase beta0001
Carbonic anhydrase 405010
Carbonic anhydrase0408
Carbonic anhydrase 150509
pregnane X receptor8008
bromodomain adjacent to zinc finger domain 2B8008
nuclear receptor subfamily 1, group I, member 23003
Nuclear hormone receptor family member daf-120011
serine/threonine-protein kinase mTOR isoform 12002
oxysterols receptor LXR-beta isoform 10011
Thymidine phosphorylase0005
Thymidylate kinase0202
Thymidine kinase0004
Thymidylate kinase0303
USP1 protein, partial150015
mitogen-activated protein kinase 1100010
Vpr2002
Albumin0022
Major prion protein0011
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0404
Sodium channel protein type 3 subunit alpha0202
UDP-glucuronosyltransferase 2B70204
Cytochrome P450 2B60123
Sodium channel protein type 4 subunit alpha0306
Sodium channel protein type 9 subunit alpha0404
Frizzled-80011
P2X purinoceptor 40101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
thyrotropin-releasing hormone receptor2002
nuclear receptor ROR-gamma isoform 1100010
Caspase-20011
Luciferase8008
Thrombopoietin2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
potassium voltage-gated channel subfamily H member 2 isoform d8008
FAD-linked sulfhydryl oxidase ALR0002
Carbonic anhydrase 120308
Carbonic anhydrase 904110
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
streptokinase A precursor0022
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Methionine--tRNA ligase, mitochondrial0011
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10203
Solute carrier family 22 member 20202
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40303
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20303
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70303
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
DNA polymerase kappa isoform 17007
cGMP-specific 3',5'-cyclic phosphodiesterase0101
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB10307
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10303
Histamine H2 receptor0202
Histamine H1 receptor0134
Histamine H2 receptor5218
Potassium-transporting ATPase subunit beta0101
Aldehyde oxidase0101
Multidrug and toxin extrusion protein 20202
Histamine H4 receptor0101
Solute carrier family 22 member 110102
Solute carrier family 22 member 40101
Solute carrier family 22 member 80203
Gamma-aminobutyric acid receptor subunit pi0606
Gamma-aminobutyric acid receptor subunit delta0606
Gamma-aminobutyric acid receptor subunit alpha-10303
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit alpha-30303
Gamma-aminobutyric acid receptor subunit alpha-10639
Gamma-aminobutyric acid receptor subunit beta-10617
Gamma-aminobutyric acid receptor subunit gamma-20628
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit beta-30628
Translocator protein0202
Translocator protein0202
Cholecystokinin receptor type A0202
Gastrin/cholecystokinin type B receptor0202
Gamma-aminobutyric acid receptor subunit alpha-50639
Gamma-aminobutyric acid receptor subunit alpha-30628
Gamma-aminobutyric acid receptor subunit alpha-20628
Gamma-aminobutyric acid receptor subunit beta-20628
Gamma-aminobutyric acid receptor subunit alpha-40617
Gamma-aminobutyric acid receptor subunit epsilon0606
Gamma-aminobutyric acid receptor subunit alpha-60617
Gamma-aminobutyric acid receptor subunit gamma-10606
Gamma-aminobutyric acid receptor subunit gamma-30606
Gamma-aminobutyric acid receptor subunit theta0606
endonuclease IV6006
dopamine D1 receptor5005
Glucocorticoid receptor06213
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10606
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Potassium voltage-gated channel subfamily A member 10011
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10607
PPM1D protein2002
RPL19A0011
Spike glycoprotein0022
Replicase polyprotein 1ab0022
NPC intracellular cholesterol transporter 1 precursor4004
nuclear factor NF-kappa-B p105 subunit isoform 12002
ras-related protein Rab-9A4004
heat shock protein HSP 90-alpha isoform 20002
transactivating tegument protein VP16 [Human herpesvirus 1]0303
COUP transcription factor 2 isoform a0101
Transmembrane protease serine 20022
Glucose transporter0101
Hexose transporter 1 0101
Procathepsin L0022
Polyunsaturated fatty acid 5-lipoxygenase0303
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0224
Solute carrier family 2, facilitated glucose transporter member 10202
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0022
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0002
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
nuclear receptor coactivator 3 isoform a0202
Thymidine kinase 2, mitochondrial0101
Thymidine kinase0203
Thymidylate synthase0306
Thymidine kinase0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0203
D(1A) dopamine receptor1001
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Deoxynucleoside kinase0101
PINK11001
Parkin1001
neutrophil cytosol factor 10101
Solute carrier family 2, facilitated glucose transporter member 30101
Solute carrier family 2, facilitated glucose transporter member 40101
Deoxycytidine kinase0001
Rap guanine nucleotide exchange factor 35005
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
15-lipoxygenase, partial100010
RAD510101
Caspase-71001
caspase-31001
huntingtin isoform 22002
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
caspase-1 isoform alpha precursor3003
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-74004
Growth factor receptor-bound protein 20101
Pantothenate synthetase0202
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0112
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Epidermal growth factor receptor0303
Vascular endothelial growth factor receptor 20101
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
CREB-binding protein0101
5-hydroxytryptamine receptor 2C0315
Phenylethanolamine N-methyltransferase0101
5-hydroxytryptamine receptor 2A0314
5-hydroxytryptamine receptor 1A0426
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A0101
Sodium-dependent noradrenaline transporter 0314
Amine oxidase [flavin-containing] B0101
5-hydroxytryptamine receptor 1B0011
5-hydroxytryptamine receptor 1D0011
5-hydroxytryptamine receptor 1F0011
5-hydroxytryptamine receptor 2B0213
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0415
Sodium-dependent serotonin transporter0213
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
Amine oxidase [flavin-containing] B0101
Sodium-dependent dopamine transporter 0213
5-hydroxytryptamine receptor 4 0011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
5-hydroxytryptamine receptor 3B0011
Sigma non-opioid intracellular receptor 10314
Gamma-aminobutyric acid 0213
Voltage-dependent L-type calcium channel subunit alpha-1F0404
Fatty acid-binding protein, liver0202
Alpha-1-acid glycoprotein 10001
Albumin0135
Translocator protein0214
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit gamma-20213
Gamma-aminobutyric acid receptor subunit delta0213
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit alpha-30213
Gamma-aminobutyric acid receptor subunit gamma-30213
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-30213
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Gamma-aminobutyric acid receptor subunit alpha-50213
Gamma-aminobutyric acid receptor subunit pi0213
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit theta0213
Gamma-aminobutyric acid receptor subunit gamma-10213
Chain A, DigA160011
Chain A, DigA160011
PAX80002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor6006
Sodium/potassium-transporting ATPase subunit alpha-1 0303
Sodium/potassium-transporting ATPase subunit beta-10303
Sodium/potassium-transporting ATPase subunit alpha-20303
Solute carrier organic anion transporter family member 4C10102
Rap guanine nucleotide exchange factor 42002
STAT3, partial0101
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40203
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
Sodium/potassium-transporting ATPase subunit beta-1 0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 1A40001
Chain A, 2-oxoglutarate Oxygenase100010
polyunsaturated fatty acid lipoxygenase ALOX124004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 18008
runt-related transcription factor 1 isoform AML1b2002
core-binding factor subunit beta isoform 22002
Glutamate receptor 11203
Glutamate receptor 31203
Glutamate receptor 41203
interferon gamma precursor0001
Sodium/nucleoside cotransporter 20303
Solute carrier family 15 member 10202
cytochrome P450 2D6 isoform 13003
hexokinase-4 isoform 12002
cytochrome P450 2C9 precursor3003
glucokinase regulatory protein2002
eyes absent homolog 2 isoform a1001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Potassium voltage-gated channel subfamily KQT member 30012
Potassium voltage-gated channel subfamily KQT member 20012
Serine hydroxymethyltransferase, mitochondrial0101
Potassium voltage-gated channel subfamily KQT member 40001
Single-stranded DNA cytosine deaminase1001
Potassium voltage-gated channel subfamily KQT member 50001
phosphoglycerate kinase2002
Fucose-binding lectin PA-IIL0101
CD209 antigen0202
P-selectin0101
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0034
transcriptional regulator ERG isoform 34004
Histone deacetylase 30303
Gamma-aminobutyric acid type B receptor subunit 20112
Gamma-aminobutyric acid type B receptor subunit 20101
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Histone deacetylase 40303
4-aminobutyrate aminotransferase, mitochondrial0102
4-aminobutyrate aminotransferase, mitochondrial0102
Histone deacetylase 10303
Sterol O-acyltransferase 10011
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Histone deacetylase 80303
Platelet glycoprotein VI0011
Sodium- and chloride-dependent GABA transporter 20101
Histone deacetylase 60303
Gamma-aminobutyric acid type B receptor subunit 10112
Histone deacetylase 90303
Histone deacetylase 50303
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, Glutamine Binding Protein0011
Neutral amino acid transporter A0202
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0202
Amino acid transporter0202
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10808
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0001
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Adenosylhomocysteinase0206
Chain A, HISTIDINE-BINDING PROTEIN0011
Plasma kallikrein0004
Carbonic anhydrase 30206
Histidine-binding periplasmic protein0011
Carbonic anhydrase 60308
Adenosine receptor A10104
Adenosine receptor A2a0003
Carbonic anhydrase 5A, mitochondrial0218
Carbonic anhydrase 70207
Carbonic anhydrase0105
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 0105
Carbonic anhydrase0105
Carbonic anhydrase0105
Carbonic anhydrase 0105
Carbonic anhydrase 130102
Carbonic anhydrase 130206
Carbonic anhydrase 140207
Carbonic anhydrase 5B, mitochondrial0207
ClpP2002
lysosomal alpha-glucosidase preproprotein2002
hypothetical protein, conserved2002
Uracil nucleotide/cysteinyl leukotriene receptor0202
Chain A, ADENOSINE DEAMINASE0101
Chain A, ADENOSINE DEAMINASE0101
glycogen synthase kinase-3 beta isoform 10033
Adenosine deaminase 0102
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Amyloid-beta precursor protein0314
Sodium/myo-inositol cotransporter 20101
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
N-glycosylase/DNA lyase0101
Myeloperoxidase0202
Formamidopyrimidine-DNA glycosylase0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Cytochrome P450 2C80202
Cytochrome P450 2A60202
Macrophage migration inhibitory factor0101
Endonuclease III-like protein 10101
DNA gyrase subunit B0202
DNA gyrase subunit A0202
Enoyl-[acyl-carrier-protein] reductase [NADH]0203
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
Capsid protein 0112
Dihydrofolate reductase0426
Potassium voltage-gated channel subfamily E member 10101
Potassium voltage-gated channel subfamily KQT member 10101
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 2 subunit alpha0303
Sodium channel protein type 3 subunit alpha0303
Sodium channel protein type 10 subunit alpha0101
Alpha-crystallin B chain0011
Lanosterol 14-alpha demethylase0001
Peroxisome proliferator-activated receptor alpha2002
Lanosterol 14-alpha demethylase0102
14-alpha sterol demethylase 0001
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0404
Intestinal-type alkaline phosphatase0303
Phospholipase A-2-activating protein0303
Leukotriene B4 receptor 10202
Leukotriene B4 receptor 20101
Cysteinyl leukotriene receptor 20011
Cysteinyl leukotriene receptor 10011
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
chaperonin-containing TCP-1 beta subunit homolog2002
Synaptic vesicle glycoprotein 2A0202
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
DNA polymerase eta isoform 12002
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Polyunsaturated fatty acid lipoxygenase ALOX150303
SLC16A10 protein0003
Monocarboxylate transporter 100003
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase2002
Thymidylate synthase 0101
Thymidylate synthase 0101
DNA polymerase beta2002
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0203
Dihydrofolate reductase 0202
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Glucose-6-phosphate 1-dehydrogenase0303
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200303
Dihydrofolate reductase 0101
Solute carrier family 22 member 60303
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
UDP-glucuronosyltransferase 1-60102
UDP-glucuronosyltransferase 1A1 0102
UDP-glucuronosyltransferase 1A40102
UDP-glucuronosyltransferase 2B10 0101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
UDP-glucuronosyltransferase 1A90002
Inosine-5'-monophosphate dehydrogenase 20202
Inosine-5'-monophosphate dehydrogenase 1 0202
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sialidase-20101
Neuropeptide Y receptor type 10202
Neuropeptide Y receptor type 20202
Sodium/iodide cotransporter0101
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 40202
5-hydroxytryptamine receptor 3B0101
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40404
5-hydroxytryptamine receptor 1A0112
Muscarinic acetylcholine receptor M50404
Alpha-2A adrenergic receptor0202
Muscarinic acetylcholine receptor M10314
Angiotensin-converting enzyme0101
D(2) dopamine receptor0202
Alpha-1B adrenergic receptor0101
Alpha-2C adrenergic receptor0202
D0101
D(3) dopamine receptor0101
Alpha-2B adrenergic receptor0101
Muscarinic acetylcholine receptor M30404
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
D(4) dopamine receptor0101
5-hydroxytryptamine receptor 70101
Alpha-1A adrenergic receptor0101
Histamine H1 receptor0213
Alpha-1B adrenergic receptor0101
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 60202
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0303
Sigma non-opioid intracellular receptor 10202
Transporter0101
Nuclear receptor subfamily 3 group C member 3 0101
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
Transporter0101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Muscarinic acetylcholine receptor M10012
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0102
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Sigma non-opioid intracellular receptor 10303
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sodium channel protein type 1 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Aldo-keto reductase family 1 member B10101
Guanine nucleotide-binding protein G1001
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Nociceptin receptor0011
Estrogen receptor beta0202
Lysine-specific demethylase 4E0101
Advanced glycosylation end product-specific receptor0011
Beta-lactamase 0101
Advanced glycosylation end product-specific receptor0011
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
NS5 0011
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0123
Adenosine receptor A30101
Adenosine receptor A2a0101
Adenosine receptor A10101
Adenosine receptor A10101
Genome polyprotein0011
DNA-directed RNA polymerase subunit beta0101
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
60 kDa heat shock protein, mitochondrial0101
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
10 kDa heat shock protein, mitochondrial0101
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Acetylcholinesterase0202
Pyruvate kinase PKM0011
Cholinesterase0101
Bifunctional epoxide hydrolase 20101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
1-deoxy-D-xylulose-5-phosphate synthase0011
1-deoxy-D-xylulose-5-phosphate synthase0011
Nrf21001
Caspase 6, apoptosis-related cysteine peptidase0001
glucocerebrosidase1001
toll-like receptor 90101
caspase recruitment domain family, member 150101
histone deacetylase 9 isoform 31001
neurotensin receptor type 10011
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
serine/threonine-protein kinase PLK11001
large T antigen0101
Beta lactamase (plasmid)0101
nucleotide-binding oligomerization domain-containing protein 1 isoform 10101
Cholinesterase0101
Acetylcholinesterase0101
Type-2 angiotensin II receptor0101
Angiotensin-converting enzyme0101
Thymidine phosphorylase0001
Thymidine kinase, cytosolic 0002
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110001
Arachidonate 5-lipoxygenase-activating protein0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 20101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
HLA class I histocompatibility antigen, A alpha chain 0011
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
atrial natriuretic peptide receptor 2 precursor1001
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
Chain A, Uracil-DNA Glycosylase0101
Protein cereblon0404
Urease subunit alpha0101
Urease subunit beta0101
Chain A, Cytidine Deaminase0101
Sodium/nucleoside cotransporter 10202
Equilibrative nucleoside transporter 20202
Equilibrative nucleoside transporter 10202
Uridine-cytidine kinase 1 0001
Solute carrier family 28 member 30202
Chain A, Arginase 10101
Cocaine esterase0101
Aldo-keto reductase family 1 member B10101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Dipeptidyl peptidase 40101
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
4-aminobutyrate aminotransferase, mitochondrial0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]