Anhidrosis

Abnormally diminished or absent perspiration. Both generalized and segmented (reduced or absent sweating in circumscribed locations) forms of the disease are usually associated with other underlying conditions.

Synonym
Hypohidrosis
Anhidrosis

Excerpt	Reference
"Anhidrosis is loss of the ability to sweat."	( Mayhew, IG; Warner, A, 1983)
"Hypohidrosis is an uncommon and reversible side effect reported in association with topiramate therapy."	( Bombardieri, R; Cerminara, C; Curatolo, P; Pinci, M; Seri, S, 2006)
"Hypohidrosis is an uncommon and reversible side effect of topiramate treatment, reported mainly in children."	( Boura, P; Georgiadis, G; Karachristianou, S; Papamichalis, E; Sarantopoulos, A, 2013)
"Hypohidrosis and anhidrosis are congenital or acquired conditions which are characterized by inadequate sweating."	( Honma, M; Iinuma, S; Ishida-Yamamoto, A; Kanno, K; Komatsu, S; Minami-Hori, M, 2015)
"Anhidrosis is an important clue for the diagnosis of AAG, a rare neurological disorder."	( Higuchi, O; Kanekura, T; Nakane, S; Sakiyama, Y; Yoneda, K; Yoshifuku, A, 2017)

Excerpt	Reference
"Anhidrosis has been recognised for over half a century, but despite some excellent epidemiological studies, there has been little progress in understanding the aetiology of the condition."	( Harris, PA; Marlin, DJ; Maykuth, PL; Nyrop, KA; Schroter, RC; Scott, CM; White, S, 1999)
"Only few cases of hypohidrosis have been described."	( Bombardieri, R; Cerminara, C; Curatolo, P; Pinci, M; Seri, S, 2006)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	35 (19.44)	23.3326
1990's	20 (11.11)	12.5806
2000's	48 (26.67)	18.1394
2010's	60 (33.33)	28.8240
2020's	17 (9.44)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
quinacrine	low	1	0
chlorine	low	1	0
salicylic acid	low	2	0
carbonic acid	low	1	0
histamine	medium	9	1
iodine	medium	36	3
dihydroxyphenylalanine	low	1	0
nitrous oxide	low	2	0
urea	low	1	0
normetanephrine	low	1	0
vanilmandelic acid	low	1	0
homovanillic acid	low	1	0
albuterol	low	1	0
aspirin	low	1	0
azathioprine	low	1	0
bupivacaine	low	1	0
caffeine	low	1	0
clenbuterol	medium	1	1
clonazepam	low	1	0
diazepam	low	1	0
enflurane	low	1	0
etizolam	low	1	0
fentanyl	low	1	0
fexofenadine	low	1	0
fluconazole	low	1	0
gabapentin	low	2	0
p-hydroxyamphetamine	low	1	0
hydroxyurea	low	2	0
lidocaine	low	1	0
2-propanol	low	1	0
isoproterenol	low	1	0
ketamine	low	1	0
mechlorethamine	low	1	0
midazolam	low	2	0
apnea	low	1	0
nitroglycerin	low	1	0
oxybutynin	low	1	0
procarbazine	low	1	0
propofol	low	2	0
propranolol	low	1	0
risperidone	low	1	0
sevoflurane	low	2	0
vorinostat	low	1	0
sumatriptan	low	1	0
terfenadine	low	1	0
zonisamide	medium	5	1
prednisolone	low	10	0
prednisolone acetate	low	1	0
prednisone	low	4	0
pilocarpine	medium	9	1
levodopa	medium	1	1
leucine	low	1	0
methacholine chloride	low	1	0
histidine	low	1	0
methylprednisolone	low	6	0
ergotamine	low	1	0
bromphenol blue	low	1	0
isoxazoles	medium	5	1
dihydroergotamine	low	1	0
methoxyhydroxyphenylglycol	low	1	0
glycopyrrolate	low	1	0
d-alpha tocopherol	low	1	0
methylprednisolone hemisuccinate	low	1	0
silver nitrate	low	1	0
trolamine salicylate	low	2	0
danazol	low	1	0
androstane-3,17-diol	low	1	0
substance p	low	1	0
vecuronium bromide	low	1	0
propiconazole	low	1	0
fomesafen	low	4	0
fluorodopa f 18	low	1	0
adapalene	low	1	0
3-iodobenzylguanidine	low	1	0
histamine phosphate	low	1	0
octadecyl palmitate	low	1	0
5-fluorodopamine	low	1	0
3-(2-carboxyindol-3-yl)propionic acid	low	1	0
n,n'-bis(salicylideneamino)ethane-manganese(ii)	low	1	0
inositol 3-phosphate	low	4	0
griseofulvin	low	1	0
mometasone furoate	low	1	0
cocaine	low	1	0
mycophenolic acid	low	1	0
bromochloroacetic acid	low	1	0
propylthiouracil	low	1	0
D-fructopyranose	medium	11	1
tamoxifen	low	1	0
androstane-3,17-diol glucuronide	low	1	0
alprostadil	low	1	0
olopatadine hydrochloride	low	1	0
phenylephrine hydrochloride	low	2	0
acitretin	low	2	0
topiramate	medium	11	1
clobetasol	low	1	0
deamino arginine vasopressin	low	1	0
selenium	low	1	0
epidermal growth factor	low	2	0
globotriaosylceramide	low	1	0
cyclosporine	low	2	0
exudates	low	1	0
acyclovir	low	1	0
eye	low	2	0

Protein Targets (1,024)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
RAR-related orphan receptor gamma	26	0	0	26
GLI family zinc finger 3	25	0	0	25
AR protein	39	0	0	39
aldehyde dehydrogenase 1 family, member A1	16	0	0	16
retinoic acid nuclear receptor alpha variant 1	24	0	0	24
retinoid X nuclear receptor alpha	22	0	0	22
estrogen nuclear receptor alpha	46	0	0	46
peroxisome proliferator-activated receptor delta	15	0	0	15
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	23	0	0	23
activating transcription factor 6	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
Histone H2A.x	16	0	0	16
thyroid hormone receptor beta isoform a	5	0	0	5
heat shock protein beta-1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
lamin isoform A-delta10	26	0	0	26
Voltage-dependent calcium channel gamma-2 subunit	17	0	0	17
Glutamate receptor 2	18	1	0	19
Chain A, 2-oxoglutarate Oxygenase	9	0	0	9
Glutamate receptor ionotropic, NMDA 1	0	4	1	8
Glutamate receptor ionotropic, NMDA 2A	0	4	1	8
Glutamate receptor ionotropic, NMDA 2B	0	6	1	10
Glutamate receptor ionotropic, NMDA 2C	0	4	1	8
Uracil nucleotide/cysteinyl leukotriene receptor	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	4	1	8
Glutamate receptor ionotropic, NMDA 3B	0	4	1	8
Glutamate receptor ionotropic, NMDA 3A	0	4	1	8
dopamine D1 receptor	4	0	0	4
thioredoxin reductase	23	0	0	23
GLS protein	19	0	0	19
Thrombopoietin	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
cytochrome P450 2D6 isoform 1	3	0	0	3
cytochrome P450 2C19 precursor	5	0	0	5
ras-related protein Rab-9A	4	0	0	4
histone acetyltransferase KAT2A isoform 1	13	0	0	13
lethal factor (plasmid)	6	0	0	6
POU domain, class 2, transcription factor 1	0	0	0	1
Spike glycoprotein	12	0	2	14
ATP-dependent phosphofructokinase	14	0	0	14
Alpha-1B adrenergic receptor	0	13	2	15
Beta-1 adrenergic receptor	0	6	2	10
Alpha-2B adrenergic receptor	0	6	2	8
Alpha-2C adrenergic receptor	0	6	2	8
Alpha-2A adrenergic receptor	0	6	2	8
Alpha-1D adrenergic receptor	0	9	2	11
Alpha-1A adrenergic receptor	0	13	2	15
Beta-2 adrenergic receptor	0	3	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Luciferase	11	0	0	11
USP1 protein, partial	14	0	0	14
TDP1 protein	34	0	0	34
Microtubule-associated protein tau	11	0	0	11
glucocorticoid receptor [Homo sapiens]	32	0	0	32
peroxisome proliferator activated receptor gamma	22	0	0	22
euchromatic histone-lysine N-methyltransferase 2	33	0	0	33
vitamin D3 receptor isoform VDRA	9	0	0	9
thyroid hormone receptor beta isoform 2	24	0	0	24
flap endonuclease 1	9	0	0	9
serine/threonine-protein kinase PLK1	2	0	0	2
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	4	0	0	4
geminin	27	0	0	27
peripheral myelin protein 22	19	0	0	19
survival motor neuron protein isoform d	9	0	0	9
ATP-binding cassette sub-family C member 3	0	32	0	32
Multidrug resistance-associated protein 4	0	32	0	33
Bile salt export pump	0	6	0	6
Bile salt export pump	0	40	0	40
Rap guanine nucleotide exchange factor 3	7	0	0	7
Cellular tumor antigen p53	26	0	0	26
Rap guanine nucleotide exchange factor 4	2	0	0	2
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Ferritin light chain	7	0	0	7
Thymidine kinase	0	1	0	1
phosphopantetheinyl transferase	12	0	0	12
Smad3	4	0	0	4
thyroid stimulating hormone receptor	12	0	0	12
EWS/FLI fusion protein	19	0	0	19
arylsulfatase A	15	0	0	15
Bloom syndrome protein isoform 1	16	0	0	16
hemoglobin subunit beta	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Solute carrier family 22 member 1	0	6	0	9
Solute carrier family 22 member 6	0	2	0	3
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	7	0	7
Cytochrome P450 2J2	0	7	0	7
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	1	0	2
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Canalicular multispecific organic anion transporter 1	0	29	0	29
Thymidine kinase	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	10	0	0	10
nuclear receptor subfamily 1, group I, member 3	22	0	0	22
estrogen-related nuclear receptor alpha	37	0	0	37
farnesoid X nuclear receptor	14	0	0	14
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	6	0	0	6
nuclear receptor ROR-gamma isoform 1	9	0	0	9
60 kDa chaperonin	0	3	0	3
Retinoic acid receptor alpha	0	1	1	2
60 kDa heat shock protein, mitochondrial	0	3	0	3
Retinoic acid receptor beta	0	1	1	2
Retinoic acid receptor gamma	0	1	1	2
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Glycine receptor subunit alpha-1	0	0	2	2
10 kDa heat shock protein, mitochondrial	0	3	0	3
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
glp-1 receptor, partial	9	0	0	9
regulator of G-protein signaling 4	11	0	0	11
NPYLR7B	0	0	3	3
thyroid stimulating hormone receptor	15	0	0	15
Beta-2 adrenergic receptor	0	10	6	17
Beta-1 adrenergic receptor	0	10	4	14
Beta-3 adrenergic receptor	0	7	3	10
Delta-type opioid receptor	0	4	2	6
Beta-2 adrenergic receptor	0	1	3	8
Beta-2 adrenergic receptor	0	2	6	9
Thromboxane-A synthase	0	3	0	3
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
ATAD5 protein, partial	9	0	0	9
D(1A) dopamine receptor	10	0	0	10
neuropeptide S receptor isoform A	4	0	0	4
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	13	0	0	13
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	4	0	0	4
hypothetical protein, conserved	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	21	0	0	21
cytochrome P450 2D6	16	0	0	16
glucocerebrosidase	3	0	0	3
Rac1 protein	0	0	1	1
IDH1	11	0	0	11
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	14	0	0	14
DNA polymerase kappa isoform 1	10	0	0	10
muscarinic acetylcholine receptor M1	10	0	0	10
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	7	0	7
Carbonic anhydrase 1	0	12	0	18
Carbonic anhydrase 2	0	13	2	23
Fatty acid-binding protein, liver	0	4	0	4
Integrin beta-3	1	2	0	3
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	1	1	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	5
Adenosine receptor A1	0	3	0	7
Adenosine receptor A2a	0	3	0	8
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	5	0	0	5
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	11	9	4	24
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	1	1	2
pregnane X nuclear receptor	30	0	0	30
cystic fibrosis transmembrane conductance regulator	0	3	0	3
DNA polymerase beta	2	0	0	2
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	16	0	16
Muscarinic acetylcholine receptor M2	0	14	4	22
Muscarinic acetylcholine receptor M4	0	12	1	15
Muscarinic acetylcholine receptor M1	0	9	1	13
Muscarinic acetylcholine receptor M3	0	7	1	11
Muscarinic acetylcholine receptor M4	0	6	1	10
Muscarinic acetylcholine receptor M5	0	6	1	10
Muscarinic acetylcholine receptor M5	0	12	1	15
Muscarinic acetylcholine receptor M2	0	8	2	14
Muscarinic acetylcholine receptor M1	0	15	4	23
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M3	0	16	2	20
Alpha-1D adrenergic receptor	0	13	3	17
5-hydroxytryptamine receptor 2C	0	17	1	18
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	4	1	2	8
5-hydroxytryptamine receptor 7	0	3	0	3
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	2	4
acetylcholinesterase	12	0	0	12
SMAD family member 2	8	0	0	8
Fumarate hydratase	8	0	0	8
SMAD family member 3	8	0	0	8
thioredoxin glutathione reductase	4	0	0	4
G	11	0	0	11
polyprotein	8	0	0	8
P53	1	0	0	1
aryl hydrocarbon receptor	9	0	0	9
peripheral myelin protein 22 isoform 1	4	0	0	4
cellular tumor antigen p53 isoform a	2	0	0	2
cytochrome P450 3A4 isoform 1	11	0	0	11
M-phase phosphoprotein 8	6	0	0	6
muscleblind-like protein 1 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	11	8	3	22
Interferon beta	18	0	0	18
HLA class I histocompatibility antigen, B alpha chain	11	0	0	11
Gamma-aminobutyric acid receptor subunit beta-1	11	8	3	22
Gamma-aminobutyric acid receptor subunit delta	11	8	3	22
Gamma-aminobutyric acid receptor subunit gamma-2	11	8	4	23
Gamma-aminobutyric acid receptor subunit alpha-5	11	8	3	22
Gamma-aminobutyric acid receptor subunit alpha-3	11	8	3	22
Gamma-aminobutyric acid receptor subunit gamma-1	11	8	3	22
Gamma-aminobutyric acid receptor subunit alpha-2	11	8	3	22
Gamma-aminobutyric acid receptor subunit alpha-4	11	8	3	22
Gamma-aminobutyric acid receptor subunit gamma-3	11	8	3	22
Gamma-aminobutyric acid receptor subunit alpha-6	11	8	3	22
Gamma-aminobutyric acid receptor subunit beta-3	11	8	3	22
Gamma-aminobutyric acid receptor subunit beta-2	11	8	4	23
GABA theta subunit	11	8	3	22
Inositol hexakisphosphate kinase 1	11	0	0	11
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	17	0	0	17
Gamma-aminobutyric acid receptor subunit epsilon	11	8	3	22
Protein-arginine deiminase type-4	0	1	0	1
cytochrome P450 2C9, partial	11	0	0	11
Angiotensin-converting enzyme	0	0	0	1
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	4	1	7
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
caspase 7, apoptosis-related cysteine protease	9	0	0	9
estrogen receptor 2 (ER beta)	12	0	0	12
caspase-3	9	0	0	9
histone deacetylase 9 isoform 3	5	0	0	5
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	2	3
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
chromobox protein homolog 1	17	0	0	17
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	2	4
Adenosine receptor A3	0	6	1	7
Replicase polyprotein 1ab	0	3	2	5
Amine oxidase [flavin-containing] A	0	3	0	3
Acetylcholinesterase	0	3	0	3
Amine oxidase [flavin-containing] B	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	5	2	8
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	3	1	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Guanine deaminase	0	1	0	1
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase 4	0	7	0	12
Carbonic anhydrase 6	0	5	0	10
Carbonic anhydrase 5A, mitochondrial	0	6	2	13
Carbonic anhydrase	0	3	0	6
Carbonic anhydrase 7	0	5	0	10
Carbonic anhydrase 9	0	6	0	12
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase 13	0	3	0	8
Carbonic anhydrase 5B, mitochondrial	0	5	0	10
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Carbonic anhydrase 15	0	4	0	7
5-hydroxytryptamine receptor 1A	0	18	3	22
5-hydroxytryptamine receptor 1B	0	15	0	15
Gamma-aminobutyric acid receptor subunit pi	0	7	0	7
Gamma-aminobutyric acid receptor subunit delta	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	4
Neuronal acetylcholine receptor subunit alpha-4	2	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	4
Neuronal acetylcholine receptor subunit beta-2	2	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	8	4	12
Gamma-aminobutyric acid receptor subunit beta-1	0	7	2	9
Gamma-aminobutyric acid receptor subunit gamma-2	0	8	3	11
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	8	3	11
Translocator protein	0	2	0	2
Translocator protein	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-3	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit beta-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	2	9
Gamma-aminobutyric acid receptor subunit epsilon	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	2	9
Gamma-aminobutyric acid receptor subunit gamma-1	0	7	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	0	7	0	7
Gamma-aminobutyric acid receptor subunit theta	0	7	0	7
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Amyloid-beta precursor protein	0	3	0	3
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
5-hydroxytryptamine receptor 2C	0	5	0	5
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
D	0	3	0	3
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent noradrenaline transporter	0	14	0	14
Sodium-dependent dopamine transporter	0	6	0	6
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
5-hydroxytryptamine receptor 6	0	1	0	1
Sodium-dependent serotonin transporter	0	9	0	9
Sodium-dependent serotonin transporter	0	3	0	4
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
D(2) dopamine receptor	0	6	1	7
Sodium-dependent dopamine transporter	0	10	0	10
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Leukotriene B4 receptor 1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Transporter	0	3	0	3
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
pregnane X receptor	5	0	0	5
progesterone receptor	15	0	0	15
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Estrogen receptor	0	6	1	8
Glucocorticoid receptor	0	9	2	16
Sex hormone-binding globulin	0	0	1	1
Cytochrome P450 1A2	0	2	0	2
Glycine receptor subunit alpha-1	0	8	0	8
Aldo-keto reductase family 1 member B1	0	12	0	12
Alpha-2A adrenergic receptor	0	13	2	16
Androgen receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	12	1	14
Alpha-2C adrenergic receptor	0	13	2	16
Glycine receptor subunit beta	0	8	0	8
Substance-K receptor	0	10	0	10
D(1A) dopamine receptor	0	14	1	15
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
5-hydroxytryptamine receptor 2A	0	19	1	20
Mu-type opioid receptor	0	7	2	9
D(3) dopamine receptor	0	18	0	18
Kappa-type opioid receptor	0	7	1	8
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Gamma-aminobutyric acid	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	1	4
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	2	2	5
Albumin	0	0	2	2
ATP-dependent translocase ABCB1	0	11	2	17
Translocator protein	0	3	1	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	1	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
Solute carrier family 22 member 2	0	3	0	4
ATP-dependent translocase ABCB1	0	5	0	5
Cytochrome P450 3A4	0	12	0	14
D(2) dopamine receptor	0	15	1	16
ATP-dependent translocase ABCB1	0	6	0	6
Alpha-1A adrenergic receptor	0	5	4	10
Alpha-1B adrenergic receptor	0	2	3	6
5-hydroxytryptamine receptor 2B	0	16	1	17
5-hydroxytryptamine receptor 6	0	11	1	12
Multidrug and toxin extrusion protein 2	0	3	0	3
Multidrug and toxin extrusion protein 1	0	5	0	5
endonuclease IV	2	0	0	2
15-lipoxygenase, partial	3	0	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
mitogen-activated protein kinase 1	3	0	0	3
Glutamate receptor 1	1	1	0	2
Glutamate receptor 3	1	1	0	2
Glutamate receptor 4	1	1	0	2
Caspase-7	1	0	0	1
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	3	0	3
Tyrosine-protein kinase Fyn	0	5	0	5
5-hydroxytryptamine receptor 1D	0	3	1	7
5-hydroxytryptamine receptor 1B	0	5	2	7
5-hydroxytryptamine receptor 5A	0	2	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
D(4) dopamine receptor	0	5	0	5
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	5	1	6
Kappa-type opioid receptor	0	1	0	1
Histamine H1 receptor	0	10	2	12
Delta-type opioid receptor	0	8	1	9
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	3	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
Solute carrier organic anion transporter family member 1A4	0	0	0	2
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Histamine H4 receptor	0	3	2	5
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	5	0	0	5
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	5	0	0	5
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	4	1	8
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	2	0	2
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	2	0	2
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	4	1	8
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
TAR DNA-binding protein 43	5	0	0	5
Histone deacetylase 1	0	4	2	9
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	4	2	9
Histone deacetylase 2	0	4	2	9
Polyamine deacetylase HDAC10	0	4	1	8
Histone deacetylase 11	0	4	1	8
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	4	2	9
Histone deacetylase 6	0	4	2	9
Histone deacetylase 9	0	4	1	8
Histone deacetylase 5	0	4	1	8
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	2	0	3
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
cytochrome P450 2C9 precursor	2	0	0	2
Transthyretin	0	1	1	3
Cytochrome P450 2C8	0	4	0	5
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Cannabinoid receptor 2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Solute carrier organic anion transporter family member 1B3	0	5	0	5
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	5	0	6
Chain A, Cruzipain	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
Chain A, Beta-lactamase	8	0	0	8
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	3	0	0	3
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase 12	0	4	0	9
Solute carrier family 22 member 3	0	1	0	2
Plasma kallikrein	0	0	0	3
Carbonic anhydrase 3	0	4	0	7
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	7	2	9
Histamine H1 receptor	0	3	3	6
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase	0	2	0	6
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase-like protein, putative	0	0	0	3
Carbonic anhydrase	0	2	0	6
Solute carrier family 22 member 1	0	1	0	2
Carbonic anhydrase	0	2	0	6
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	3	0	5
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	2	0	4
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Carbonic anhydrase 14	0	4	0	9
Histamine H3 receptor	0	2	2	4
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
ClpP	1	0	0	1
NFKB1 protein, partial	2	0	0	2
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Solute carrier family 22 member 8	0	0	0	1
Stromelysin-1	0	0	2	2
Urease subunit alpha	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	2	0	2
Inositol monophosphatase 1	1	0	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Transmembrane protease serine 2	0	0	2	2
Procathepsin L	0	0	2	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Angiotensin-converting enzyme 2	0	0	2	2
Beta-1 adrenergic receptor	0	1	2	5
beta-2 adrenergic receptor	2	0	0	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
Beta-2 adrenergic receptor	0	4	1	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	2	1	3
D(1A) dopamine receptor	4	0	0	4
Taste receptor type 2 member 38	0	0	2	3
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Acetylcholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
Cholinesterase	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
Polyphenol oxidase 2	0	1	0	3
Tyrosinase	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
phosphoglycerate kinase	1	0	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
PPM1D protein	5	0	0	5
thyrotropin-releasing hormone receptor	2	0	0	2
galanin receptor type 3	0	1	0	1
nonstructural protein 1	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
UDP-glucuronosyltransferase 2B7	0	2	0	2
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	3	0	4
UDP-glucuronosyltransferase 1A4	0	2	0	3
UDP-glucuronosyltransferase 2B10	0	2	0	2
isocitrate dehydrogenase 1, partial	1	0	0	1
67.9K protein	6	0	0	6
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Progesterone receptor	0	3	1	5
Guanine nucleotide-binding protein G	3	0	0	3
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Alpha-synuclein	2	0	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Cytochrome P450 2C19	0	4	0	4
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Beta-secretase 1	0	1	1	2
Trace amine-associated receptor 1	0	0	1	1
Genome polyprotein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
Tyrosine-protein kinase ABL1	0	2	0	2
Tubulin alpha-1A chain	0	1	1	3
Tubulin beta chain	0	1	1	2
Tubulin beta-4A chain	0	1	1	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Integrin alpha-V	0	1	0	1
Tubulin beta chain	0	1	1	3
Tubulin alpha-3C chain	0	1	1	3
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
Fibroblast growth factor receptor 1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Cholecystokinin receptor type A	0	3	1	4
Melanocortin receptor 5	0	4	0	4
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	0	1
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	1	1	3
Beta-tubulin	0	1	0	1
Tubulin beta-8 chain	0	1	1	3
Tubulin beta-2B chain	0	0	1	3
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
Similar to alpha-tubulin isoform 1	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	0	2
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Cytochrome P450 2A6	0	1	1	2
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
luciferase	0	0	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 1A	0	4	3	7
Cytochrome P450 2D6	0	3	0	3
D(3) dopamine receptor	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Endothelin-1 receptor	0	1	1	2
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
5-hydroxytryptamine receptor 7	0	3	1	4
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
N	0	1	0	1
tumor susceptibility gene 101 protein	1	0	0	1
Glutathione reductase, mitochondrial	0	1	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	0	1	1
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Trypanothione reductase	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Cytochrome P450 3A5	0	0	0	1
ATP-binding cassette sub-family C member 8	0	1	1	2
Angiotensin-converting enzyme	0	4	0	4
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Transporter	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	4	1	5
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Carboxypeptidase M	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
interferon gamma precursor	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
streptokinase A precursor	0	0	1	1
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor	0	0	1	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	2	0	2
Protein kinase C alpha type	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Protein kinase C eta type	0	1	0	1
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	2	0	2
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Parkin	1	0	0	1
XBP1	0	1	0	1
huntingtin isoform 2	1	0	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
C-C chemokine receptor type 5	0	2	0	2
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Prolyl endopeptidase	0	2	0	2
Carbonic anhydrase-related protein 11	0	0	0	1
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	2	0	2
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Histone deacetylase 8	0	1	0	1
Nrf2	1	0	0	1
PAX8	0	0	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Gli1	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
Histone deacetylase 1	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Bromodomain-containing protein 4	0	1	0	1
Nuclear receptor corepressor 1	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Protein Tat	0	0	1	1
Heat shock protein HSP 90-alpha	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Aminopeptidase N	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Apoptosis regulator BAX	0	0	1	1
Histone deacetylase 1	0	1	0	1
Histone deacetylase	0	1	0	1
Renin	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	1	3
Histone deacetylase	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Carboxypeptidase B2	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
REST corepressor 3	0	1	0	1
Histone deacetylase	0	1	0	1
Nuclear receptor corepressor 2	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Amine oxidase [flavin-containing]	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Research

Studies (180)

Protein Targets (1,024)

Anhidrosis

Synonyms(2)

Research Excerpts

Overview

Context

Research

Studies (180)

Drugs Studied (122)

Protein Targets (1,024)