Page last updated: 2024-08-01 18:15:49
3',4',5'-O-trimethyltricetin
Description
3',4',5'-O-trimethyltricetin : A trimethoxyflavone that is the 3',4',5'-tri-O-methyl ether of tricetin. [CHeBI]
Cross-References
Synonyms (45)
Synonym |
nsc-123410 |
4h-1-benzopyran-4-one,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)- |
5,4',5'-trimethoxyflavone |
nsc123410 |
mls002707300 , |
5,4',5'-trimethoxy flavone |
flavone,7-dihydroxy-3',4',5'-trimethoxy- |
18103-42-9 |
5,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)-4h-chromen-4-one |
4h-1-benzopyran-4-one, 5,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)- |
flavone, 5,7-dihydroxy-3',4',5'-trimethoxy- |
5,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one |
5,7-dihydroxy-3',4',5'-trimethoxy flavone |
5, 7-dihydroxy-3',4',5'-trimethoxyflavone |
5,7-dihydroxy-3',4',5'-trimethoxyflavon |
smr001574694 |
CHEMBL486590 |
5,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)-4h-1-benzopyran-4-one |
tricetin 3',4',5'-trimethyl ether |
3',4',5'-o-trimethyltricetin |
5,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)-4-benzopyrone |
CHEBI:543745 , |
5,7-dihydroxy-3',4',5'-trimethoxyflavone |
LMPK12110880 |
2j9jj5n2h7 , |
nsc 123410 |
tricin 4'-methyl ether |
einecs 242-001-0 |
unii-2j9jj5n2h7 |
C19807 |
mfcd00016924 |
SCHEMBL4918477 |
AKOS025287600 |
5,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)-4h-chromen-4-one # |
CPCPHNWWTJLXKQ-UHFFFAOYSA-N |
DTXSID70171059 |
5-7-dihydroxy-3-4-5-trimethoxyflavone |
flavone, 5,7-dihydroxy-3',4',5'-trimethoxy- (8ci) |
5,7-dihydroxy-3',4',5'-trimethoxy-flavone |
FS-8799 |
FT-0756628 |
Q27105170 |
XD161933 |
5,7-dihydroxy-3?,4?,5?-trimethoxyflavone |
3',4',5'-tri-o-methyl-tricetin |
Drug Classes (3)
Class | Description |
trimethoxyflavone | A methoxyflavone that is flavone substituted by three methoxy groups. |
dihydroxyflavone | Any hydroxyflavone in which two ring hydrogens are replaced by hydroxy substituents. |
3',5'-dimethoxyflavone | A dimethoxyflavone in which the hydroxy groups at positions 3' and 5' have been replaced by methoxy groups. |
Bioassays (10)
Assay ID | Title | Year | Journal | Article |
AID403036 | Cytotoxicity against human NCI-H460 cells at 58 uM | 2005 | Journal of natural products, Aug, Volume: 68, Issue:8 ISSN: 0163-3864 | Constituents of Vittaria anguste-elongata and their biological activities. |
AID404069 | In vivo antitumor activity against mouse L1210 cells | | Journal of natural products, , Volume: 42, Issue:1 ISSN: 0163-3864 | Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones. |
AID403037 | Cytotoxicity against human SF268 cells at 58 uM | 2005 | Journal of natural products, Aug, Volume: 68, Issue:8 ISSN: 0163-3864 | Constituents of Vittaria anguste-elongata and their biological activities. |
AID400607 | Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression at 10 uM after 18 hrs measured as microunits of tissue factor/10'5 cells | 1996 | Journal of natural products, Mar, Volume: 59, Issue:3 ISSN: 0163-3864 | Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes. |
AID356482 | Antihistaminic activity in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced beta-hexosaminidase release preincubated for 10 mins before DNP-BSA challenge | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9 ISSN: 0163-3864 | Tricin from a malagasy connaraceous plant with potent antihistaminic activity. |
AID356483 | Cytotoxicity against rat RBL2H3 cells at 500 uM by optical microscope | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9 ISSN: 0163-3864 | Tricin from a malagasy connaraceous plant with potent antihistaminic activity. |
AID1434690 | Inhibition of sucrose loaded POPC/POPE/POPS/PtdIns(3,4,5)P3 (59:20:20:1) liposome binding to eGFP-fused PDK1 PH domain (unknown origin) expressed in Escherichia coli BL21 at 20 uM after 10 mins by fluorescence spectrophotometry based pull down assay relat | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 ISSN: 1464-3405 | Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
Research
Studies (7)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 3 (42.86) | 29.6817 |
2010's | 3 (42.86) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 8 (100.00%) | 84.16% |
Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
xanthomicrol | | dihydroxyflavone; trimethoxyflavone | antineoplastic agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eupatorin | | dihydroxyflavone; polyphenol; trimethoxyflavone | anti-inflammatory agent; antineoplastic agent; apoptosis inducer; Brassica napus metabolite; calcium channel blocker; P450 inhibitor; vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
nevadensin | | dihydroxyflavone; trimethoxyflavone | plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
salvigenin | | monohydroxyflavone; trimethoxyflavone | antilipemic drug; antineoplastic agent; apoptosis inhibitor; autophagy inducer; hypoglycemic agent; immunomodulator; neuroprotective agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cirsilineol | | dihydroxyflavone; trimethoxyflavone | antineoplastic agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chrysosplenol c | | trihydroxyflavone; trimethoxyflavone | antineoplastic agent; antiviral agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
2-(4-hydroxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one | | monohydroxyflavone; trimethoxyflavone | | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5,6,7-trimethoxyflavone | | trimethoxyflavone | anti-HSV-1 agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eupatilin | | dihydroxyflavone; trimethoxyflavone | anti-inflammatory agent; anti-ulcer drug; antineoplastic agent; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ayanin | | dihydroxyflavone; trimethoxyflavone | plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
dexmedetomidine | | trihydroxyflavone; trimethoxyflavone | antineoplastic agent; metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
pachypodol | | dihydroxyflavone; trimethoxyflavone | antiemetic; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
santin | | dihydroxyflavone; trimethoxyflavone | plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
centaureidin | | trihydroxyflavone; trimethoxyflavone | antineoplastic agent; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
eupatin | | flavonols; trihydroxyflavone; trimethoxyflavone | | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
7,8-dihydroxyflavone | | dihydroxyflavone | antidepressant; antineoplastic agent; antioxidant; plant metabolite; tropomyosin-related kinase B receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
baicalin | | dihydroxyflavone; glucosiduronic acid; glycosyloxyflavone; monosaccharide derivative | antiatherosclerotic agent; antibacterial agent; anticoronaviral agent; antineoplastic agent; antioxidant; cardioprotective agent; EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; ferroptosis inhibitor; neuroprotective agent; non-steroidal anti-inflammatory drug; plant metabolite; prodrug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
swertisin | | dihydroxyflavone; flavone C-glycoside; monomethoxyflavone; monosaccharide derivative; polyphenol | adenosine A1 receptor antagonist; anti-inflammatory agent; antioxidant; hypoglycemic agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
skullcapflavone ii | | dihydroxyflavone; tetramethoxyflavone | anti-asthmatic drug; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
spinosin | | dihydroxyflavone; flavone C-glycoside; monomethoxyflavone | anxiolytic drug; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4',6-dihydroxyflavone | | dihydroxyflavone | | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
cirsimaritin | | dihydroxyflavone; dimethoxyflavone | | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4',6-dihydroxy-5,7-dimethoxyflavone | | dihydroxyflavone; dimethoxyflavone | | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
saponarin | | C-glycosyl compound; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
6-prenylchrysin | | 7-hydroxyflavonol; dihydroxyflavone | | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
sideroxylin | | dihydroxyflavone; monomethoxyflavone | plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ladanein | | dihydroxyflavone; dimethoxyflavone | antiviral agent; plant metabolite; radical scavenger | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
acacetin | | dihydroxyflavone; monomethoxyflavone | anticonvulsant; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
apigetrin | | beta-D-glucoside; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative | antibacterial agent; metabolite; non-steroidal anti-inflammatory drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
apiin | | beta-D-glucoside; dihydroxyflavone; glycosyloxyflavone | EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chrysin | | 7-hydroxyflavonol; dihydroxyflavone | anti-inflammatory agent; antineoplastic agent; antioxidant; EC 2.7.11.18 (myosin-light-chain kinase) inhibitor; hepatoprotective agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
chrysosplenetin b | | dihydroxyflavone; tetramethoxyflavone | antiviral agent; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
genkwanin | | dihydroxyflavone; monomethoxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
robinin | | dihydroxyflavone; glycosyloxyflavone | plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
wogonin | | dihydroxyflavone; monomethoxyflavone | angiogenesis inhibitor; antineoplastic agent; cyclooxygenase 2 inhibitor; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
4',7-dihydroxyflavone | | dihydroxyflavone | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
rhoifolin | | dihydroxyflavone; glycosyloxyflavone; neohesperidoside | metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
alvocidib | | dihydroxyflavone; hydroxypiperidine; monochlorobenzenes; tertiary amino compound | antineoplastic agent; antirheumatic drug; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
casticin | | dihydroxyflavone; tetramethoxyflavone | apoptosis inducer; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | | dihydroxyflavone; monomethoxyflavone | antineoplastic agent; EC 1.14.13.39 (nitric oxide synthase) inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5,7-dihydroxy-4',6-dimethoxyflavone | | dihydroxyflavone; dimethoxyflavone | plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
ermanin | | dihydroxyflavone; dimethoxyflavone | anti-inflammatory agent; antimycobacterial drug; antineoplastic agent; apoptosis inducer; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
5,4'-dihydroxy-7,3'-dimethoxyflavone | | dihydroxyflavone; dimethoxyflavone | anti-allergic agent; anti-inflammatory agent; antibacterial agent; antioxidant; melanin synthesis inhibitor; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
lespenefril | | alpha-L-rhamnoside; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative; polyphenol | anti-inflammatory agent; antidepressant; antineoplastic agent; apoptosis inducer; bone density conservation agent; hypoglycemic agent; immunomodulator; plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
syringetin | | 3',5'-dimethoxyflavone; 3'-methoxyflavones; 7-hydroxyflavonol; dimethoxyflavone; tetrahydroxyflavone | metabolite; platelet aggregation inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
naringenin | | 4'-hydroxyflavanones; trihydroxyflavanone | | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
flavone | | flavones | metabolite; nematicide | 1996 | 2017 | 17.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
eriodictyol | | flavanones | | 2017 | 2017 | 7.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 |
d-alpha tocopherol | | alpha-tocopherol | algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
cromolyn sodium | | organic sodium salt | anti-asthmatic drug; drug allergen | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
tangeretin | | pentamethoxyflavone | antineoplastic agent; plant metabolite | 1996 | 2003 | 24.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
hesperetin | | 3'-hydroxyflavanones; 4'-methoxyflavanones; monomethoxyflavanone; trihydroxyflavanone | antineoplastic agent; antioxidant; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
homoeriodictyol | | 3'-methoxyflavanones; 4'-hydroxyflavanones; monomethoxyflavanone; trihydroxyflavanone | flavouring agent; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
umuhengerin | | | | 1996 | 1996 | 28.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
4'-methoxyflavone | | ether; flavonoids | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
5,7-dimethoxyflavone | | dimethoxyflavone | plant metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
4',5,6,7-tetramethoxyflavone | | tetramethoxyflavone | antimutagen; plant metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
eupatorin | | dihydroxyflavone; polyphenol; trimethoxyflavone | anti-inflammatory agent; antineoplastic agent; apoptosis inducer; Brassica napus metabolite; calcium channel blocker; P450 inhibitor; vasodilator agent | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
karanjin | | extended flavonoid | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
daidzin | | 7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; monosaccharide derivative | plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
sinensetin | | pentamethoxyflavone | plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
sideritoflavone | | ether; flavonoids | | 2003 | 2003 | 21.0 | high | 0 | 0 | 0 | 1 | 0 | 0 |
isosakuranetin | | (2S)-flavan-4-one; 4'-methoxyflavanones; dihydroxyflavanone; monomethoxyflavanone | plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
cirsimaritin | | dihydroxyflavone; dimethoxyflavone | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
pinocembrin | | | | 2017 | 2017 | 7.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 |
sakuranetin | | | | 2017 | 2017 | 7.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 |
5,7-dimethoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one | | ether; flavonoids | | 2017 | 2017 | 7.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 |
naringenin | | (2S)-flavan-4-one; naringenin | expectorant; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
taxifolin | | taxifolin | metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
isonaringin | | (2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; disaccharide derivative; rutinoside | anti-inflammatory agent; antioxidant; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
3',4'-dimethoxyflavone | | | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
silybin | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
alpinetin | | ether; flavonoids | | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
quercetin | | 7-hydroxyflavonol; pentahydroxyflavone | antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger | 1996 | 2017 | 17.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
acacetin | | dihydroxyflavone; monomethoxyflavone | anticonvulsant; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
apigenin | | trihydroxyflavone | antineoplastic agent; metabolite | 1996 | 2017 | 18.7 | low | 0 | 0 | 1 | 1 | 1 | 0 |
luteolin | | 3'-hydroxyflavonoid; tetrahydroxyflavone | angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; c-Jun N-terminal kinase inhibitor; EC 2.3.1.85 (fatty acid synthase) inhibitor; immunomodulator; nephroprotective agent; plant metabolite; radical scavenger; vascular endothelial growth factor receptor antagonist | 1996 | 2017 | 18.7 | low | 0 | 0 | 1 | 1 | 1 | 0 |
gossypetin | | 7-hydroxyflavonol; hexahydroxyflavone | plant metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
chrysoeriol | | monomethoxyflavone; trihydroxyflavone | antineoplastic agent; antioxidant; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
rutin | | disaccharide derivative; quercetin O-glucoside; rutinoside; tetrahydroxyflavone | antioxidant; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
kaempferol | | 7-hydroxyflavonol; flavonols; tetrahydroxyflavone | antibacterial agent; geroprotector; human blood serum metabolite; human urinary metabolite; human xenobiotic metabolite; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
amentoflavone | | biflavonoid; hydroxyflavone; ring assembly | angiogenesis inhibitor; antiviral agent; cathepsin B inhibitor; P450 inhibitor; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
baicalein | | trihydroxyflavone | angiogenesis inhibitor; anti-inflammatory agent; antibacterial agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 4.1.1.17 (ornithine decarboxylase) inhibitor; ferroptosis inhibitor; geroprotector; hormone antagonist; plant metabolite; prostaglandin antagonist; radical scavenger | 1996 | 2003 | 24.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
chrysin | | 7-hydroxyflavonol; dihydroxyflavone | anti-inflammatory agent; antineoplastic agent; antioxidant; EC 2.7.11.18 (myosin-light-chain kinase) inhibitor; hepatoprotective agent; plant metabolite | 1996 | 2017 | 18.7 | low | 0 | 0 | 1 | 1 | 1 | 0 |
datiscetin | | 7-hydroxyflavonol; tetrahydroxyflavone | | 1996 | 2017 | 17.5 | medium | 0 | 0 | 1 | 0 | 1 | 0 |
diosmetin | | 3'-hydroxyflavonoid; monomethoxyflavone; trihydroxyflavone | angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; bone density conservation agent; cardioprotective agent; plant metabolite; tropomyosin-related kinase B receptor agonist; vasodilator agent | 1996 | 2017 | 17.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
fisetin | | 3'-hydroxyflavonoid; 7-hydroxyflavonol; tetrahydroxyflavone | anti-inflammatory agent; antioxidant; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; metabolite; plant metabolite | 1996 | 2017 | 17.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
galangin | | 7-hydroxyflavonol; trihydroxyflavone | antimicrobial agent; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; plant metabolite | 1996 | 2017 | 17.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
genkwanin | | dihydroxyflavone; monomethoxyflavone | metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
hinokiflavone | | aromatic ether; biflavonoid; hydroxyflavone | antineoplastic agent; metabolite; neuroprotective agent | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
3-methylquercetin | | 7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone | anticoagulant; EC 1.14.18.1 (tyrosinase) inhibitor; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
kaempferide | | 7-hydroxyflavonol; monomethoxyflavone; trihydroxyflavone | antihypertensive agent; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
morin | | 7-hydroxyflavonol; pentahydroxyflavone | angiogenesis modulating agent; anti-inflammatory agent; antibacterial agent; antihypertensive agent; antineoplastic agent; antioxidant; EC 5.99.1.2 (DNA topoisomerase) inhibitor; hepatoprotective agent; metabolite; neuroprotective agent | 1996 | 2017 | 17.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
myricetin | | 7-hydroxyflavonol; hexahydroxyflavone | antineoplastic agent; antioxidant; cyclooxygenase 1 inhibitor; food component; geroprotector; hypoglycemic agent; plant metabolite | 1996 | 2017 | 17.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
norwogonin | | trihydroxyflavone | antioxidant; metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
quercetagetin | | flavonols; hexahydroxyflavone | antioxidant; antiviral agent; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
rhamnetin | | monomethoxyflavone; tetrahydroxyflavone | anti-inflammatory agent; antioxidant; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
robinetin | | 7-hydroxyflavonol; pentahydroxyflavone | plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
sciadopitysin | | biflavonoid; hydroxyflavone; methoxyflavone; ring assembly | bone density conservation agent; platelet aggregation inhibitor | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
scutellarein | | tetrahydroxyflavone | metabolite | 2003 | 2017 | 14.0 | low | 0 | 0 | 0 | 1 | 1 | 0 |
tamarixetin | | 7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone | antioxidant; metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
tricetin | | pentahydroxyflavone | antineoplastic agent; metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
tricin | | 3'-methoxyflavones; dimethoxyflavone; trihydroxyflavone | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; metabolite | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
daidzein | | 7-hydroxyisoflavones | antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; phytoestrogen; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
psi-baptigenin | | 7-hydroxyisoflavones; benzodioxoles | antiprotozoal drug; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
syringetin | | 3',5'-dimethoxyflavone; 3'-methoxyflavones; 7-hydroxyflavonol; dimethoxyflavone; tetrahydroxyflavone | metabolite; platelet aggregation inhibitor | 1996 | 2017 | 17.5 | medium | 0 | 0 | 1 | 0 | 1 | 0 |
tectochrysin | | monohydroxyflavone; monomethoxyflavone | antidiarrhoeal drug; antineoplastic agent; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
4',7-dihydroxyflavone | | dihydroxyflavone | metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
astragalin | | beta-D-glucoside; kaempferol O-glucoside; monosaccharide derivative; trihydroxyflavone | plant metabolite; trypanocidal drug | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
3,3'-di-o-methylquercetin | | 3'-methoxyflavones; dimethoxyflavone; trihydroxyflavone | antibacterial agent; antineoplastic agent; apoptosis inducer; plant metabolite | 1996 | 1996 | 28.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
fustin | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
3',4'-didemethylnobiletin | | | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
isorhamnetin 3-o-glucoside | | beta-D-glucoside; glycosyloxyflavone; monomethoxyflavone; monosaccharide derivative; trihydroxyflavone | metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
tiliroside | | cinnamate ester; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone | plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
avicularin | | alpha-L-arabinofuranoside; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone | hepatoprotective agent; plant metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
eupatorin-5-methyl ether | | | | 1996 | 1996 | 28.0 | high | 0 | 0 | 1 | 0 | 0 | 0 |
dihydrorobinetin | | | | 1996 | 1996 | 28.0 | high | 0 | 0 | 1 | 0 | 0 | 0 |
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Tricin from a malagasy connaraceous plant with potent antihistaminic activity.Journal of natural products, , Volume: 66, Issue:9, 2003
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Tricin from a malagasy connaraceous plant with potent antihistaminic activity.Journal of natural products, , Volume: 66, Issue:9, 2003
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Tricin from a malagasy connaraceous plant with potent antihistaminic activity.Journal of natural products, , Volume: 66, Issue:9, 2003
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Tricin from a malagasy connaraceous plant with potent antihistaminic activity.Journal of natural products, , Volume: 66, Issue:9, 2003
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Tricin from a malagasy connaraceous plant with potent antihistaminic activity.Journal of natural products, , Volume: 66, Issue:9, 2003
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.Bioorganic & medicinal chemistry letters, , 02-01, Volume: 27, Issue:3, 2017
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.Journal of natural products, , Volume: 59, Issue:3, 1996
Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.Journal of natural products, , Volume: 42, Issue:1,