Page last updated: 2024-09-28

Incompetence, Pulmonary Valve

Backflow of blood from the PULMONARY ARTERY into the RIGHT VENTRICLE due to imperfect closure of the PULMONARY VALVE.

Synonyms(11)

Synonym
Valve Regurgitation, Pulmonary
Regurgitation, Pulmonary
Incompetence, Pulmonary Valve
Pulmonary Valve Regurgitation
Pulmonary Valve Insufficiency
Pulmonary Valve Incompetence
Valve Incompetence, Pulmonary
Pulmonary Regurgitation
Regurgitation, Pulmonary Valve
Insufficiency, Pulmonary Valve
Valve Insufficiency, Pulmonary

Research Excerpts

Context

ExcerptReference
"Chronic pulmonary regurgitation has been associated with RV dysfunction and decreased exercise performance."( Bogaert, J; Daenen, W; Dumoulin, M; Dymarkowsky, S; Eyskens, B; Gewillig, M; Reybrouck, T, 2000)

Research

Studies (147)

TimeframeStudies, This Condition (%)All Conditions %
pre-199082 (55.78)23.3326
1990's10 (6.80)12.5806
2000's20 (13.61)18.1394
2010's28 (19.05)28.8240
2020's7 (4.76)9.53
DrugIndicatedRelationship StrengthStudiesTrials
ammonium hydroxide0low10
butyric acid0low10
lactic acid0low10
pyruvic acid0low10
hydroxyindoleacetic acid0low20
theophylline0low10
aspirin0low20
camphor, (+-)-isomer0low10
cefixime0low10
chlorpromazine0low10
decamethonium0low10
diphenhydramine0low10
fenfluramine0low10
fluorouracil0low10
furosemide0low20
gentamicin0low10
glutaral0low10
guaifenesin0low10
ibuprofen0low10
lidocaine0low20
indomethacin0low30
isoflurane0low10
isoproterenol0low20
ketamine0low10
losartan0low10
meperidine0low10
milrinone0low10
apnea0low20
neostigmine0low10
nicardipine0low10
octopamine0low10
pentobarbital0low10
phentermine0low10
phenylbutazone0low10
propranolol0low10
nikethamide0low10
prednisolone0low20
prednisone0low30
penicillin g0low10
metaraminol0low10
adenosine diphosphate0low10
carbostyril0low10
methoxamine0low10
phencyclidine0low10
methylprednisolone0low10
meglumine0low10
acridines0low10
aminophylline0low20
galantamine0low10
methysergide0low10
n-pentyl nitrite0low50
deoxycytidine0low10
2'-deoxyadenosine0low10
vancomycin0low10
megestrol0low10
platinum0low10
technetium0low30
trolamine salicylate0low10
cetylpyridinium chloride anhydrous0low10
4-methoxyamphetamine0low10
tobramycin0low10
dobutamine0low30
captopril0low10
pergolide0low10
capecitabine0low10
adenosine0low10
dexfenfluramine0low10
prethcamide0low10
atropine0low10
elastin0low20
oleic acid0low10
propylthiouracil0low10
nitinol0low10
thromboxane a20low10
alprostadil0low20
nalorphine0low10
morphine0low20
indium0low10
ramipril0medium52
phosphorus0low10
heroin0low10
triolein0low10
mocetinostat0low10
indocyanine green0low20
glucagon0low10
sodium pertechnetate tc 99m0low20
cardiovascular agents0low30
natriuretic peptide, brain0medium141
ascorbic acid0low40
warfarin0low30
folic acid0low10

Protein Targets (1,067)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
TDP1 protein230023
nuclear factor erythroid 2-related factor 2 isoform 27007
Thymidine kinase, cytosolic0001
Adenosine receptor A108110
Deoxycytidine kinase0002
Adenosine deaminase 0002
AAA family ATPase 0002
5-hydroxytryptamine receptor 2C0415
5-hydroxytryptamine receptor 2A0415
5-hydroxytryptamine receptor 1A013216
5-hydroxytryptamine receptor 1B011112
5-hydroxytryptamine receptor 1D0213
5-hydroxytryptamine receptor 1F0213
5-hydroxytryptamine receptor 2B0415
5-hydroxytryptamine receptor 60112
Sodium-dependent serotonin transporter0617
Sodium-dependent serotonin transporter0617
5-hydroxytryptamine receptor 7 0213
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0112
5-hydroxytryptamine receptor 4 0112
5-hydroxytryptamine receptor 3B0112
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase4004
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
thioredoxin reductase190019
GALC protein2002
GLI family zinc finger 3190019
nuclear receptor subfamily 1, group I, member 3120012
cytochrome P450 family 3 subfamily A polypeptide 4220022
glucocorticoid receptor [Homo sapiens]250025
retinoic acid nuclear receptor alpha variant 1190019
retinoid X nuclear receptor alpha140014
estrogen-related nuclear receptor alpha220022
Carbonic anhydrase 0101
Carbonic anhydrase 0101
arylsulfatase A130013
Carbonic anhydrase0101
euchromatic histone-lysine N-methyltransferase 2230023
Bloom syndrome protein isoform 16006
thyroid hormone receptor beta isoform a3003
nuclear factor erythroid 2-related factor 2 isoform 1160016
geminin210021
peripheral myelin protein 22100010
survival motor neuron protein isoform d7007
muscleblind-like protein 1 isoform 15005
Gamma-aminobutyric acid receptor subunit pi6219
ATP-binding cassette sub-family C member 3023023
Multidrug resistance-associated protein 4023025
Carbonic anhydrase0101
Solute carrier family 22 member 60606
Carbonic anhydrase 120519
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump035035
Glycogen phosphorylase, muscle form0101
Renin0404
Carbonic anhydrase 107113
Carbonic anhydrase 207112
Carbonic anhydrase 20202
Cytochrome P450 1A20213
Carbonic anhydrase 30518
Cathepsin B0101
Cytochrome P450 3A40617
Steryl-sulfatase0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80202
Cytochrome P450 2D60516
Cytochrome P450 2A60101
Cytochrome P450 2C9 013013
Androgen receptor0404
Gamma-aminobutyric acid receptor subunit beta-16219
Translocator protein0112
Gamma-aminobutyric acid receptor subunit delta6219
Gamma-aminobutyric acid receptor subunit gamma-26219
Gamma-aminobutyric acid receptor subunit alpha-56219
Gamma-aminobutyric acid receptor subunit alpha-36219
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60202
Carbonic anhydrase 40518
Carbonic anhydrase 60518
Gamma-aminobutyric acid receptor subunit gamma-16219
Gamma-aminobutyric acid receptor subunit alpha-26219
Carbonic anhydrase 5A, mitochondrial0101
Serum paraoxonase/arylesterase 10303
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-46219
Gamma-aminobutyric acid receptor subunit gamma-36219
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-66219
Adenosine receptor A2a08111
Delta-type opioid receptor0507
Cytochrome P450 2C190303
Delta-type opioid receptor0427
Mu-type opioid receptor0429
Carbonic anhydrase 5A, mitochondrial0519
Carbonic anhydrase0101
Kappa-type opioid receptor0506
Carbonic anhydrase 70518
Carbonic anhydrase0101
D(1A) dopamine receptor3104
Corticosteroid 11-beta-dehydrogenase isozyme 10202
Carbonic anhydrase0101
D(2) dopamine receptor0517
Gamma-aminobutyric acid receptor subunit alpha-163110
Gamma-aminobutyric acid receptor subunit beta-36219
Gamma-aminobutyric acid receptor subunit beta-26219
Cholinesterase0505
Carbonic anhydrase 0101
Mu-type opioid receptor0516
Fatty-acid amide hydrolase 10202
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0617
Squalene synthase0202
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 90519
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase 30101
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0101
Sigma intracellular receptor 20202
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10202
Renin0101
Carbonic anhydrase 0101
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130416
GABA theta subunit6219
Canalicular multispecific organic anion transporter 1023023
Carbonic anhydrase 40202
Carbonic anhydrase 150203
Acidic mammalian chitinase0101
Carbonic anhydrase 130305
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon6219
Carbonic anhydrase 0101
Carbonic anhydrase 140519
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0519
Chain A, Ferritin light chain4004
Microtubule-associated protein tau130013
Smad33003
aldehyde dehydrogenase 1 family, member A1140014
alpha-galactosidase4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
flap endonuclease 18008
DNA polymerase iota isoform a (long)5005
DNA topoisomerase 2-alpha0001
Acetylcholinesterase08110
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE120012
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein270027
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 4110011
estrogen nuclear receptor alpha330033
NPYLR7B0022
IDH1110011
Histone H2A.x5005
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 15005
nuclear receptor ROR-gamma isoform 15005
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10404
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70022
Sodium/nucleoside cotransporter 20404
Voltage-dependent calcium channel gamma-2 subunit6006
Rap guanine nucleotide exchange factor 35005
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0707
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20202
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0225
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30539
Heat shock 70 kDa protein 1A 0213
Heat shock cognate 71 kDa protein0022
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0113
Glutamate receptor 26006
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A30303
Adenosine receptor A2a04511
Adenosine receptor A2b0114
Adenosine receptor A2b0214
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A104310
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0405
Adenosine receptor A10213
Adenosine kinase0001
Equilibrative nucleoside transporter 20404
Phosphatidylinositol 4-kinase type 2-beta0405
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10404
Phosphatidylinositol 4-kinase type 2-alpha0405
Solute carrier family 28 member 30404
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0405
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
HPr kinase/phosphorylase0011
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0112
Endoplasmic reticulum chaperone BiP0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0101
Mu-type opioid receptor07412
Delta-type opioid receptor07311
Kappa-type opioid receptor07311
Endoplasmin0112
P2Y purinoceptor 20011
P2X purinoceptor 10011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 14004
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
P2Y purinoceptor 110011
P2Y purinoceptor 120112
Sensor protein kinase WalK0101
P2X purinoceptor 20011
peroxisome proliferator activated receptor gamma150015
Cellular tumor antigen p53200020
Thromboxane-A synthase 0202
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20022
Solute carrier organic anion transporter family member 2A10102
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0213
Solute carrier organic anion transporter family member 2A10102
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
USP1 protein, partial130013
lamin isoform A-delta10210021
ATAD5 protein, partial6006
D(1A) dopamine receptor8008
neuropeptide S receptor isoform A4004
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase9009
RAR-related orphan receptor gamma190019
thioredoxin glutathione reductase3003
vitamin D (1,25- dihydroxyvitamin D3) receptor170017
chromobox protein homolog 1160016
thyroid hormone receptor beta isoform 2160016
lethal(3)malignant brain tumor-like protein 1 isoform I1001
lethal factor (plasmid)4004
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0202
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor08211
Spike glycoprotein7119
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
Chain A, 2-oxoglutarate Oxygenase8008
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 85005
GLS protein160016
thyroid stimulating hormone receptor7007
hypothetical protein, conserved2002
EWS/FLI fusion protein110011
cytochrome P450 2D6120012
glucocerebrosidase4004
peroxisome proliferator-activated receptor delta8008
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
DNA polymerase kappa isoform 17007
muscarinic acetylcholine receptor M17007
Prostaglandin-H2 D-isomerase0202
Prostaglandin G/H synthase 1 0405
Prostaglandin G/H synthase 2 0304
Fatty acid-binding protein, liver0404
Integrin beta-32103
Myeloperoxidase0202
Prostaglandin G/H synthase 10607
Seed linoleate 13S-lipoxygenase-10202
Integrin alpha-IIb2103
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10606
Substance-P receptor0303
Prostaglandin G/H synthase 20819
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0202
Nuclear receptor ROR-gamma7007
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20606
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0303
Solute carrier family 22 member 200404
Solute carrier family 22 member 60404
Sigma non-opioid intracellular receptor 1011112
Sigma non-opioid intracellular receptor 10213
pregnane X nuclear receptor140014
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0606
5-hydroxytryptamine receptor 4012012
Muscarinic acetylcholine receptor M207212
Muscarinic acetylcholine receptor M40619
Muscarinic acetylcholine receptor M10428
Muscarinic acetylcholine receptor M30428
Muscarinic acetylcholine receptor M40428
Muscarinic acetylcholine receptor M50428
Muscarinic acetylcholine receptor M50619
Muscarinic acetylcholine receptor M20429
Muscarinic acetylcholine receptor M107212
Muscarinic acetylcholine receptor M10013
Muscarinic acetylcholine receptor M307211
Alpha-1D adrenergic receptor08212
5-hydroxytryptamine receptor 2C012214
Muscarinic acetylcholine receptor M40113
Histamine H2 receptor4017
5-hydroxytryptamine receptor 70404
Reverse transcriptase/RNaseH 0012
Muscarinic acetylcholine receptor0112
Chain A, Nitrile Hydratase alpha subunit0101
Chain B, Nitrile Hydratase beta subunit0101
SMAD family member 25005
SMAD family member 35005
Lysine-specific demethylase 4E0101
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
thyroid stimulating hormone receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
Free fatty acid receptor 30011
Histone deacetylase 30404
Histone deacetylase 40303
Histone deacetylase 10404
Histone deacetylase 70303
Histone deacetylase 20404
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0202
Histone deacetylase 80303
Histone deacetylase 60303
Histone deacetylase 90202
Histone deacetylase 50303
Methyl-accepting chemotaxis protein NahY0011
apical membrane antigen 1, AMA11001
farnesoid X nuclear receptor100010
67.9K protein6006
Liver carboxylesterase 10003
Chain A, angiotensin converting enzyme0101
Chain A, angiotensin converting enzyme0101
15-lipoxygenase, partial1001
phosphopantetheinyl transferase100010
Thrombopoietin4004
Metallo-beta-lactamase type 20113
peripheral myelin protein 22 isoform 14004
M-phase phosphoprotein 87007
transient receptor potential cation channel subfamily V member 11001
Prothrombin0101
Neprilysin0101
Neprilysin0202
Leukotriene A-4 hydrolase0314
EEF1AKMT4-ECE2 readthrough transcript protein0101
Angiotensin-converting enzyme 0415
Angiotensin-converting enzyme0708
Leukotriene A-4 hydrolase0101
Thymidine phosphorylase0011
Endothelin-converting enzyme 10101
Succinyl-diaminopimelate desuccinylase0202
Angiotensin-converting enzyme0202
Solute carrier family 15 member 10101
Beta-lactamase TEM0203
TAR DNA-binding protein 434004
Beta-lactamase 0203
Beta-lactamase 0202
Angiotensin-converting enzyme 2 0213
Beta-lactamase class B VIM-2 0113
ATP-dependent phosphofructokinase9009
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
Chain A, serum paraoxonase0101
Neutrophil cytosol factor 10101
Poly [ADP-ribose] polymerase tankyrase-20101
hypoxia-inducible factor 1 alpha subunit8008
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)100010
progesterone receptor110011
caspase-32002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)4004
activating transcription factor 67007
thyrotropin-releasing hormone receptor2002
v-jun sarcoma virus 17 oncogene homolog (avian)8008
vitamin D3 receptor isoform VDRA110011
heat shock protein beta-15005
Caspase-20011
ATPase family AAA domain-containing protein 57007
Ataxin-2110011
Proteasome subunit beta type-110001
Fumarate hydratase4004
NFKB1 protein, partial4004
NADPH oxidase 10101
G110011
polyprotein4004
Snq2p0001
Adenylate cyclase type 1 0202
Caspase-71001
Spike glycoprotein0112
Replicase polyprotein 1ab0112
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a2002
potassium voltage-gated channel subfamily H member 2 isoform d6006
caspase-31001
histone deacetylase 9 isoform 31001
atrial natriuretic peptide receptor 2 precursor2002
ras-related protein Rab-9A3003
serine/threonine-protein kinase mTOR isoform 15005
cytochrome P450 3A4 isoform 16006
histone acetyltransferase KAT2A isoform 17007
Proteasome subunit alpha type-70001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Transmembrane protease serine 20112
Glutamate receptor ionotropic, NMDA 2D0303
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0303
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Bile salt export pump0505
Potassium channel subfamily K member 20213
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 110011
Albumin0369
Albumin0033
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Major prion protein0011
Tyrosine-protein kinase Fyn0202
Procathepsin L0213
Aldo-keto reductase family 1 member B10606
ATP-dependent translocase ABCB10608
5-hydroxytryptamine receptor 1A0404
Alpha-2A adrenergic receptor08312
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0213
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0213
Polyunsaturated fatty acid lipoxygenase ALOX150303
D(2) dopamine receptor08211
Alpha-1B adrenergic receptor0617
Sphingomyelin phosphodiesterase0101
Alpha-2C adrenergic receptor0528
D0303
D(3) dopamine receptor0505
Alpha-2B adrenergic receptor0617
D(2) dopamine receptor0202
Proteasome subunit beta type-10001
Substance-K receptor0202
D(1A) dopamine receptor08110
D(4) dopamine receptor0304
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0617
UDP-glucuronosyltransferase 1A40001
Alpha-2A adrenergic receptor0617
Alpha-1D adrenergic receptor0617
Sodium-dependent noradrenaline transporter 0606
Sodium-dependent dopamine transporter0404
Histamine H2 receptor0202
D(1B) dopamine receptor0303
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A010212
Trypanothione reductase0202
D(4) dopamine receptor0303
Histamine H1 receptor0113
Melanocortin receptor 40202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70213
Histamine H1 receptor0404
Glutamate receptor ionotropic, NMDA 1 0516
D(3) dopamine receptor09010
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0303
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
5-hydroxytryptamine receptor 2B010111
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0617
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
5-hydroxytryptamine receptor 60819
Cytochrome P450 2J20707
Gastrin/cholecystokinin type B receptor0101
Proteasome subunit alpha type-60012
Calmodulin 0112
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0516
Glutamate receptor ionotropic, NMDA 2C0517
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Sodium-dependent dopamine transporter 0404
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10505
Aldehyde oxidase0202
Potassium voltage-gated channel subfamily H member 2012012
Glutamate receptor ionotropic, NMDA 2A0505
Glutamate receptor ionotropic, NMDA 2B0505
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Sodium channel protein type 5 subunit alpha0404
Glutamate receptor ionotropic, NMDA 2C0303
Sodium channel protein type 9 subunit alpha0202
Glutamate receptor ionotropic, NMDA 2D0516
Nuclear receptor subfamily 3 group C member 3 0404
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0303
Glutamate receptor ionotropic, NMDA 3B0516
Inositol hexakisphosphate kinase 1110011
D0202
Sodium channel protein type 2 subunit alpha0101
Proteasome subunit beta type-70001
Sodium channel protein type 3 subunit alpha0202
Glutamate receptor ionotropic, NMDA 3A0516
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0202
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial110011
Acetylcholinesterase0101
Acetylcholinesterase0202
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-30101
Thymidine kinase 2 0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
Luciferase6006
huntingtin isoform 23003
Histamine N-methyltransferase0001
Solute carrier family 22 member 10101
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0101
Histamine H3 receptor0001
Solute carrier family 22 member 20101
dopamine D1 receptor5005
glp-1 receptor, partial5005
aryl hydrocarbon receptor7007
mu-type opioid receptor isoform MOR-10022
5-hydroxytryptamine receptor 2A0022
Tyrosine-protein kinase Lck0101
Beta-2 adrenergic receptor06310
Beta-1 adrenergic receptor0628
POU domain, class 2, transcription factor 10002
Chain A, Uracil Phosphoribosyltransferase0101
endonuclease IV3003
Skn7p0001
pregnane X receptor3003
nonstructural protein 15005
hemoglobin subunit beta1001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Vpr2002
Solute carrier family 22 member 80103
Amyloid-beta precursor protein1001
Thymidylate synthase0202
Aromatase0202
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Dihydrofolate reductase0011
acid sphingomyelinase1001
lysosomal alpha-glucosidase preproprotein1001
Thymidylate synthase0202
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10202
Alpha-synuclein1102
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30202
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Glucose-6-phosphate 1-dehydrogenase0101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0202
Multidrug and toxin extrusion protein 10404
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Broad substrate specificity ATP-binding cassette transporter ABCG20303
Chain A, ACETYLCHOLINESTERASE0101
Chain A, Acetylcholinesterase0101
Acetylcholinesterase0505
Acetylcholinesterase0202
Cholinesterase0505
Vascular endothelial growth factor receptor 1 0101
Acetylcholinesterase 0101
Vascular endothelial growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
Acetylcholinesterase0101
Prolyl endopeptidase0101
Small conductance calcium-activated potassium channel protein 30101
Carboxylic ester hydrolase 0202
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
cytochrome P450 2C9 precursor3003
Uracil nucleotide/cysteinyl leukotriene receptor0202
transcriptional regulator ERG isoform 32002
importin subunit beta-1 isoform 11001
snurportin-11001
Acid-sensing ion channel 30101
Solute carrier organic anion transporter family member 1A40101
Dihydrofolate reductase0101
Fatty acid-binding protein, intestinal0101
Polyunsaturated fatty acid 5-lipoxygenase0204
UDP-glucuronosyltransferase 2B70002
Prostaglandin G/H synthase 10202
Caspase-10102
Prostaglandin G/H synthase 2 0304
UDP-glucuronosyltransferase 1A30002
Aldo-keto reductase family 1 member C30303
Caspase-30101
Solute carrier organic anion transporter family member 1A10101
Caspase-40101
Caspase-50101
Caspase-90101
Acid-sensing ion channel 10101
Prostaglandin G/H synthase 20203
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0304
Solute carrier family 22 member 80404
Dehydrogenase/reductase SDR family member 90101
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Cruzipain2002
Parkin3003
bromodomain adjacent to zinc finger domain 2B3003
Prostaglandin E synthase0101
3',5'-cyclic-AMP phosphodiesterase 0202
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Neuronal acetylcholine receptor subunit alpha-40101
Interleukin-80101
Androgen receptor0213
Neuronal acetylcholine receptor subunit beta-20101
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Sodium- and chloride-dependent GABA transporter 10101
Indoleamine 2,3-dioxygenase 10101
Nitric oxide synthase, inducible0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Peroxisome proliferator-activated receptor gamma0011
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G3003
Prostaglandin D2 receptor 0202
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Solute carrier family 22 member 70001
Dehydrogenase/reductase SDR family member 90101
Solute carrier organic anion transporter family member 1B30404
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10404
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
Beta-1 adrenergic receptor 0125
beta-2 adrenergic receptor1001
hexokinase-4 isoform 12002
glucokinase regulatory protein2002
Beta-2 adrenergic receptor0416
Beta-3 adrenergic receptor0325
Beta-1 adrenergic receptor0428
Beta-2 adrenergic receptor0011
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0314
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0213
Alpha-1A adrenergic receptor0136
Alpha-1B adrenergic receptor0024
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380023
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0011
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0337
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Potassium channel subfamily K member 30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Atrial natriuretic peptide receptor 30101
Thromboxane A2 receptor 0102
Type-1A angiotensin II receptor 0213
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0404
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0327
Type-1 angiotensin II receptor0112
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0404
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0404
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0404
Platelet glycoprotein VI0113
Type-1 angiotensin II receptor0112
Kappa-type opioid receptor0417
Mu-type opioid receptor0418
Macrophage migration inhibitory factor0202
PPM1D protein3003
nuclear receptor subfamily 1, group I, member 22002
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
DNA polymerase III, partial1001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Phosphodiesterase 0303
cytochrome P450 2C19 precursor2002
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
Aurora kinase A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Dual specificity protein kinase TTK0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0202
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Aurora kinase B0101
Inner centromere protein0101
Phosphodiesterase 0101
Nuclear receptor corepressor 10101
Integrin beta-10101
Integrin alpha-40101
Nuclear receptor corepressor 20101
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
ATP-dependent translocase ABCB10202
Acyl-CoA desaturase 10101
Histidine decarboxylase0022
ATP-dependent translocase ABCB10202
Proteinase-activated receptor 10112
Kappa-type opioid receptor0326
Nociceptin receptor0101
Mu-type opioid receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
UDP-glucuronosyltransferase 1A1 0001
Atrial natriuretic peptide receptor 10101
NPC intracellular cholesterol transporter 1 precursor1001
atrial natriuretic peptide receptor 1 precursor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Equilibrative nucleoside transporter 10101
B2 bradykinin receptor0101
Chymotrypsinogen A0101
Beta-lactamase0101
Quinolone resistance protein NorA0101
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Malate dehydrogenase, cytoplasmic0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Transient receptor potential cation channel subfamily A member 10011
5-hydroxytryptamine receptor 3A0011
Trace amine-associated receptor 10011
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, BCL-2-RELATED PROTEIN A10011
putative potassium channel subunit0011
serine-protein kinase ATM isoform a1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
serine/threonine-protein kinase PLK11001
bcl-2-like protein 11 isoform 10011
Fatty-acid amide hydrolase 10101
Sterol O-acyltransferase 10101
Trypsin0101
Fatty acid-binding protein, liver0011
Coagulation factor VII0101
DNA topoisomerase 10101
Tissue factor0101
Fatty acid-binding protein, adipocyte0202
Protein kinase C alpha type0001
Tyrosine-protein phosphatase non-receptor type 10101
Sterol O-acyltransferase 10101
Fatty acid-binding protein 50101
Peroxisome proliferator-activated receptor delta0001
Peroxisome proliferator-activated receptor alpha1012
Rap guanine nucleotide exchange factor 41001
Transient receptor potential cation channel subfamily V member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-11 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
streptokinase A precursor0011
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Solute carrier family 15 member 10101
Beta-lactamase0001
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Beta-lactamase 0001
Class D beta-lactamase0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Beta-lactamase VIM-1 0001
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit beta-20011
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Lysosomal Pro-X carboxypeptidase0101
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Trace amine-associated receptor 10011
Estrogen receptor 10101
fMet-Leu-Phe receptor0101
Cyclooxygenase-2 0101
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0202
Endothelin-1 receptor0112
5-hydroxytryptamine receptor 1B0213
Neuromedin-K receptor0011
Cholecystokinin receptor type A0112
Vasopressin V1a receptor0112
Nuclear receptor subfamily 2 group E member 10022
NADH-cytochrome b5 reductase 3 0101
Thyroid peroxidase0101
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Vasopressin V2 receptor0001
Adenosine receptor A2a0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Adenosine receptor A2b0001
Palmitoleoyl-protein carboxylesterase NOTUM0011
Endochitinase B10101
Phospholipase A-2-activating protein0101
Protein Rev 0011
Chain A, Cytidine Deaminase0101
Protein cereblon0202
Uridine-cytidine kinase 1 0001
60 kDa heat shock protein, mitochondrial0101
10 kDa heat shock protein, mitochondrial0101
D-alanyl-D-alanine dipeptidase0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Transporter0101
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]