Page last updated: 2024-09-28

Craniofacial Pain Syndromes

Neuralgic syndromes which feature chronic or recurrent FACIAL PAIN as the primary manifestation of disease. Disorders of the trigeminal and facial nerves are frequently associated with these conditions.

Synonyms(5)

Synonym
Craniofacial Pain Syndromes
Sphenopalatine Neuralgia
Myofacial Pain Syndromes
Facial Neuralgia
Facial Pain Syndromes

Research Excerpts

Overview

ExcerptReference
"Facial neuralgias are uncommon and usually present in the dental clinic."( Agbelusi, GA; Danesi, MA; Wright, AA, 2005)

Treatment

ExcerptReference
"Despite the fact that essential facial neuralgia is a well known clinical entity as relates to its evolution and treatment, its physiopathology is still a controversial issue."( Djoumessi, A; Djoumessi, S; Mendomo, EM; Ndobo-Epoy, P; Onana, J, 2002)
"Twelve patients with facial neuralgias diagnosed and treated in dental clinic of the Lagos University Teaching Hospital were studies."( Agbelusi, GA; Danesi, MA; Wright, AA, 2005)

Research

Studies (217)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990149 (68.66)23.3326
1990's17 (7.83)12.5806
2000's35 (16.13)18.1394
2010's14 (6.45)28.8240
2020's2 (0.92)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low50
salicylic acid0low30
formaldehyde0low10
glycerol0low50
histamine0low150
imidazole0low20
phenol0low20
pyridoxine0medium11
thiamine0low10
phenytoin0medium81
acetaminophen0medium11
amitriptyline0low30
aspirin0low20
baclofen0low40
bupivacaine0low20
caffeine0low20
carbamazepine0medium343
chlorambucil0low10
chlordiazepoxide0low10
chlormezanone0low10
chlorpromazine0low10
clomipramine0low20
clonazepam0low10
clonidine0medium11
dapsone0low10
diazepam0low10
brl 428100low10
fluoxetine0low10
gabapentin0low50
phenelzine0low10
lidocaine0medium101
imipramine0low10
khellin0low10
lamotrigine0low10
maprotiline0low10
mephenesin0medium11
mepivacaine0low20
methadone0low10
sansert0low10
nylidrin0low10
oxybutynin0medium11
phenacetin0low10
phenobarbital0low10
piracetam0low10
procaine0low60
propranolol0low20
sulfamethoxazole0low10
sumatriptan0low10
trimethoprim0low10
hydrocortisone acetate0low10
prednisolone0low20
lysergic acid diethylamide0low10
prednisone0low30
methylprednisolone acetate0low10
aspartic acid0medium11
colchicine0low10
chloroform0low10
methylprednisolone0low10
phenothiazine0low10
chlorphenesin0low10
thiophenes0low20
ergotamine0low110
methohexital0low10
methysergide0low60
2-aminopurine0low10
hydantoins0low60
fluoromethane0low10
glycopyrrolate0low10
benperidol0low10
gadolinium0low20
trolamine salicylate0low100
phenyl acetate0low10
oxcarbazepine0low10
substance p0low20
propiconazole0low90
fomesafen0low60
sertraline0medium11
cortisone0low10
oxytocin0low10
inositol 3-phosphate0low30
cocaine0low10
enkephalin, leucine0low10
dipyrone0medium11
stilbenes0low10
D-fructopyranose0low10
digoxin0low10
dothiepin hydrochloride0medium21
phenylephrine hydrochloride0low80
levetiracetam0low10
oxycodone0low10
topiramate0low10
morphine0low10
dextromethorphan0medium11
heroin0low10
ammonium sulfate0low10
jaw0low60
beta-endorphin0low10
ziconotide0low10
ozocerite0low10
piperidines0low20
vitamin b 120low20
lysergic acid0low10
acyclovir0low20
folic acid0low10
olanzapine0low10
eye0low40
ego0low10

Protein Targets (1,013)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Beta-lactamase110011
thioredoxin reductase260026
aldehyde dehydrogenase 1 family, member A1240024
IDH1140014
Phosphatidylinositol 4-kinase alpha0202
Xanthine dehydrogenase/oxidase0101
Guanine nucleotide-binding protein G3003
TAR DNA-binding protein 435005
Phosphatidylinositol 4-kinase type 2-beta0202
Phosphatidylinositol 4-kinase type 2-alpha0202
Phosphatidylinositol 4-kinase beta0202
RAR-related orphan receptor gamma270027
ATAD5 protein, partial150015
GLS protein200020
Microtubule-associated protein tau110011
Smad3100010
thyroid stimulating hormone receptor190019
nuclear receptor subfamily 1, group I, member 3260026
progesterone receptor180018
EWS/FLI fusion protein130013
retinoic acid nuclear receptor alpha variant 1290029
retinoid X nuclear receptor alpha250025
estrogen-related nuclear receptor alpha360036
estrogen nuclear receptor alpha470047
peroxisome proliferator activated receptor gamma220022
aryl hydrocarbon receptor160016
chromobox protein homolog 1220022
thyroid hormone receptor beta isoform 2280028
peripheral myelin protein 22170017
cytochrome P450 3A4 isoform 1160016
Gamma-aminobutyric acid receptor subunit pi168226
ATP-binding cassette sub-family C member 3035035
Multidrug resistance-associated protein 4035036
Solute carrier family 22 member 60405
Carbonic anhydrase 120508
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0808
Voltage-dependent calcium channel gamma-2 subunit120012
Bile salt export pump051051
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 1012016
Carbonic anhydrase 2012118
Myoglobin0101
Cytochrome P450 1A10214
Cytochrome P450 1A20519
Prostaglandin G/H synthase 10303
Carbonic anhydrase 30406
Cytochrome P450 3A4015117
Cytochrome P450 2D6011113
Cytochrome P450 2C9 016016
Polyunsaturated fatty acid lipoxygenase ALOX150404
Gamma-aminobutyric acid receptor subunit beta-1168226
Sulfotransferase 1A1 0002
Gamma-aminobutyric acid receptor subunit delta168226
Gamma-aminobutyric acid receptor subunit gamma-2168428
UDP-glucuronosyltransferase 1-60102
Glutamate receptor 2120012
Gamma-aminobutyric acid receptor subunit alpha-5168226
Gamma-aminobutyric acid receptor subunit alpha-3168226
Arachidonate 5-lipoxygenase-activating protein0202
UDP-glucuronosyltransferase 1A1 0102
Carbonic anhydrase 40407
Prostaglandin G/H synthase 10707
Carbonic anhydrase 60609
Gamma-aminobutyric acid receptor subunit gamma-1168226
Gamma-aminobutyric acid receptor subunit alpha-2168226
Gamma-aminobutyric acid receptor subunit alpha-4168226
Gamma-aminobutyric acid receptor subunit gamma-3168226
Gamma-aminobutyric acid receptor subunit alpha-6168226
Carbonic anhydrase 5A, mitochondrial0418
Prostaglandin G/H synthase 20607
Carbonic anhydrase 70407
Nuclear receptor ROR-gamma91111
Cytochrome P450 2J2013013
Gamma-aminobutyric acid receptor subunit alpha-1169429
Gamma-aminobutyric acid receptor subunit beta-3168226
Gamma-aminobutyric acid receptor subunit beta-2168428
Carbonic anhydrase 90508
GABA theta subunit168226
Canalicular multispecific organic anion transporter 1034034
Carbonic anhydrase 150406
Carbonic anhydrase 130407
Gamma-aminobutyric acid receptor subunit epsilon168226
Carbonic anhydrase 140407
Carbonic anhydrase 5B, mitochondrial0407
toxin B0001
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Chain A, Ferritin light chain7007
Thymidine kinase 0101
phosphopantetheinyl transferase100010
TDP1 protein370037
arylsulfatase A120012
euchromatic histone-lysine N-methyltransferase 2370037
activating transcription factor 6120012
Histone H2A.x110011
Bloom syndrome protein isoform 1140014
hemoglobin subunit beta1001
atrial natriuretic peptide receptor 1 precursor5005
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
lamin isoform A-delta10320032
Solute carrier family 22 member 1 012018
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0001
POU domain, class 2, transcription factor 20001
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60203
Thymidine kinase 0101
Solute carrier family 22 member 80102
Thymidine kinase0101
USP1 protein, partial170017
NFKB1 protein, partial7007
cytochrome P450 family 3 subfamily A polypeptide 4210021
cytochrome P450 2D6210021
cytochrome P450 2D6 isoform 1140014
D(1A) dopamine receptor150015
atrial natriuretic peptide receptor 2 precursor7007
serine/threonine-protein kinase mTOR isoform 17007
nuclear factor erythroid 2-related factor 2 isoform 1250025
muscarinic acetylcholine receptor M1190019
Polyunsaturated fatty acid lipoxygenase ALOX15B9009
Voltage-dependent L-type calcium channel subunit alpha-1F0617
5-hydroxytryptamine receptor 4024024
Albumin0055
High affinity nerve growth factor receptor0123
Aldo-keto reductase family 1 member B1016016
Muscarinic acetylcholine receptor M2016219
Muscarinic acetylcholine receptor M4015015
Muscarinic acetylcholine receptor M10505
Muscarinic acetylcholine receptor M30404
Muscarinic acetylcholine receptor M40303
5-hydroxytryptamine receptor 2C015015
Muscarinic acetylcholine receptor M50404
Muscarinic acetylcholine receptor M5017017
Alpha-2A adrenergic receptor022428
Muscarinic acetylcholine receptor M20505
Muscarinic acetylcholine receptor M1017220
Angiotensin-converting enzyme0909
D(2) dopamine receptor023125
5-hydroxytryptamine receptor 2A017118
Alpha-2B adrenergic receptor022226
Alpha-2C adrenergic receptor019324
5-hydroxytryptamine receptor 1A028332
Muscarinic acetylcholine receptor M3017118
D(1A) dopamine receptor017119
D(1B) dopamine receptor0405
UDP-glucuronosyltransferase 1A40105
Sodium-dependent noradrenaline transporter 021223
Histamine H2 receptor09211
Alpha-1D adrenergic receptor016321
5-hydroxytryptamine receptor 2A028230
5-hydroxytryptamine receptor 2C028129
5-hydroxytryptamine receptor 1B022022
5-hydroxytryptamine receptor 1D0718
5-hydroxytryptamine receptor 1F0606
5-hydroxytryptamine receptor 2B015015
5-hydroxytryptamine receptor 60404
Histamine H1 receptor0516
Sodium-dependent serotonin transporter020323
5-hydroxytryptamine receptor 7 0606
5-hydroxytryptamine receptor 5A0404
5-hydroxytryptamine receptor 5B0404
Histamine H1 receptor017320
D(3) dopamine receptor021022
Sodium channel protein type 1 subunit alpha0505
Sodium channel protein type 4 subunit alpha07010
UDP-glucuronosyltransferase 1A30003
5-hydroxytryptamine receptor 3A0505
5-hydroxytryptamine receptor 2B023124
Alpha-1A adrenergic receptor015318
Histamine H2 receptor163121
D(1A) dopamine receptor7007
5-hydroxytryptamine receptor 6023124
5-hydroxytryptamine receptor 70808
Voltage-dependent N-type calcium channel subunit alpha-1B0505
Sodium channel protein type 7 subunit alpha0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0617
Sodium-dependent dopamine transporter 020222
Potassium voltage-gated channel subfamily H member 2024024
Voltage-dependent L-type calcium channel subunit alpha-1S0617
Voltage-dependent L-type calcium channel subunit alpha-1C09110
Sodium channel protein type 5 subunit alpha0707
Sodium channel protein type 9 subunit alpha0808
Sigma non-opioid intracellular receptor 10415
5-hydroxytryptamine receptor 4 0404
Nuclear receptor subfamily 3 group C member 3 0909
Sodium channel protein type 2 subunit alpha0606
Ataxin-2210021
Sigma non-opioid intracellular receptor 1020121
5-hydroxytryptamine receptor 3B0505
Sodium channel protein type 3 subunit alpha0707
Sodium channel protein type 11 subunit alpha0303
Sodium channel protein type 8 subunit alpha0303
Histamine H3 receptor0527
Sodium channel protein type 10 subunit alpha0404
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE190019
Chain A, TYROSYL-DNA PHOSPHODIESTERASE9009
cytochrome P450 2C19 precursor7007
lethal factor (plasmid)110011
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0418
Glutamate receptor ionotropic, NMDA 1 0507
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0507
Glutamate receptor ionotropic, NMDA 2B0608
Glutamate receptor ionotropic, NMDA 2C0507
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, NMDA 2D0507
Glutamate receptor ionotropic, NMDA 3B0507
Carbonic anhydrase 40204
Glutamate receptor ionotropic, NMDA 3A0507
Chain A, Phospholipase A2 isoform 30011
Chain A, 2-oxoglutarate Oxygenase110011
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 89009
AR protein410041
hypothetical protein, conserved1001
glucocorticoid receptor [Homo sapiens]270027
glucocerebrosidase4004
peroxisome proliferator-activated receptor delta190019
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
DNA polymerase iota isoform a (long)6006
DNA polymerase kappa isoform 16006
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0202
Fatty acid-binding protein, liver0303
Integrin beta-32103
Myeloperoxidase0404
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb2103
Glutathione hydrolase 1 proenzyme0101
Adenosine receptor A10507
Adenosine receptor A2a0418
Substance-P receptor0303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0303
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10516
GLI family zinc finger 3380038
regulator of G-protein signaling 4170017
67.9K protein7007
histone acetyltransferase KAT2A isoform 1110011
Gamma-aminobutyric acid type B receptor subunit 20224
Gamma-aminobutyric acid type B receptor subunit 20303
Gamma-aminobutyric acid type B receptor subunit 10224
Gamma-aminobutyric acid type B receptor subunit 10202
ATP-dependent phosphofructokinase130013
glp-1 receptor, partial110011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
farnesoid X nuclear receptor130013
pregnane X nuclear receptor260026
thyroid stimulating hormone receptor110011
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
potassium voltage-gated channel subfamily H member 2 isoform d130013
Rap guanine nucleotide exchange factor 32002
D(4) dopamine receptor0708
Spike glycoprotein181322
Chain A, Cruzipain3003
acetylcholinesterase120012
relaxin receptor 1 isoform 11001
Interferon beta180018
Potassium channel subfamily K member 30303
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20325
Potassium channel subfamily K member 90101
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
v-jun sarcoma virus 17 oncogene homolog (avian)180018
thyroid hormone receptor beta isoform a120012
DNA polymerase beta4004
nuclear receptor ROR-gamma isoform 1100010
geminin330033
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0336
Adenosine receptor A30415
Replicase polyprotein 1ab0437
Amine oxidase [flavin-containing] A0505
Acetylcholinesterase0404
Amine oxidase [flavin-containing] B0505
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Adenosine receptor A30101
Adenosine receptor A2a0326
Adenosine receptor A2b0102
Adenosine receptor A2b0214
Adenosine receptor A10114
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0012
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Guanine deaminase0101
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a180018
nuclear factor erythroid 2-related factor 2 isoform 2100010
mitogen-activated protein kinase 18008
Vpr2002
Major prion protein0033
Cellular tumor antigen p53280028
Sodium channel protein type 1 subunit alpha0606
Sodium channel protein type 2 subunit alpha0707
Sodium channel protein type 3 subunit alpha0505
UDP-glucuronosyltransferase 2B70102
Cytochrome P450 2B60112
Frizzled-80011
P2X purinoceptor 40202
Luciferase9009
GALC protein6006
Thrombopoietin5005
thioredoxin glutathione reductase5005
caspase 7, apoptosis-related cysteine protease7007
bromodomain adjacent to zinc finger domain 2B7007
vitamin D (1,25- dihydroxyvitamin D3) receptor260026
caspase-37007
peripheral myelin protein 22 isoform 16006
vitamin D3 receptor isoform VDRA130013
FAD-linked sulfhydryl oxidase ALR0002
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
survival motor neuron protein isoform d7007
muscleblind-like protein 1 isoform 15005
ATPase family AAA domain-containing protein 5110011
Solute carrier organic anion transporter family member 1B30303
Gamma-aminobutyric acid receptor subunit alpha-10404
Gamma-aminobutyric acid receptor subunit beta-10404
Gamma-aminobutyric acid receptor subunit alpha-20404
Gamma-aminobutyric acid receptor subunit alpha-30404
Gamma-aminobutyric acid receptor subunit alpha-109413
Translocator protein0225
Gamma-aminobutyric acid receptor subunit gamma-209312
Gamma-aminobutyric acid receptor subunit alpha-40404
Gamma-aminobutyric acid receptor subunit gamma-20404
Gamma-aminobutyric acid receptor subunit beta-309211
Cholecystokinin receptor type A0303
Gastrin/cholecystokinin type B receptor0303
Gamma-aminobutyric acid receptor subunit alpha-509312
Gamma-aminobutyric acid receptor subunit alpha-309211
Gamma-aminobutyric acid receptor subunit alpha-209211
M-phase phosphoprotein 87007
hypoxia-inducible factor 1 alpha subunit7007
Proteasome subunit beta type-110001
Fumarate hydratase8008
estrogen receptor 2 (ER beta)140014
NADPH oxidase 10202
G110011
polyprotein8008
Snq2p0003
Adenylate cyclase type 1 0202
Caspase-73003
Spike glycoprotein0134
Replicase polyprotein 1ab0134
cellular tumor antigen p53 isoform a6006
caspase-33003
histone deacetylase 9 isoform 32002
heat shock protein beta-13003
ras-related protein Rab-9A7007
Proteasome subunit alpha type-70001
Transmembrane protease serine 20134
Glutamate receptor ionotropic, NMDA 2D0202
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0202
HLA class I histocompatibility antigen, B alpha chain 110011
Albumin0135
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Tyrosine-protein kinase Fyn0202
Procathepsin L0134
ATP-dependent translocase ABCB1011016
5-hydroxytryptamine receptor 1A09413
Replicase polyprotein 1a0134
Replicase polyprotein 1ab0134
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Alpha-1B adrenergic receptor013215
Sphingomyelin phosphodiesterase0202
D0707
D(3) dopamine receptor0707
Alpha-2B adrenergic receptor010313
D(2) dopamine receptor0101
Proteasome subunit beta type-10001
Substance-K receptor0404
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor010313
Alpha-2A adrenergic receptor010313
Alpha-1D adrenergic receptor011213
Sodium-dependent dopamine transporter010010
D(1B) dopamine receptor0505
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
Trypanothione reductase0404
D(4) dopamine receptor0606
Histamine H1 receptor0336
Melanocortin receptor 40202
Melanocortin receptor 50404
Pleiotropic ABC efflux transporter of multiple drugs0306
5-hydroxytryptamine receptor 70617
Mu-type opioid receptor010415
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor07412
Kappa-type opioid receptor07412
Melanocortin receptor 30202
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
Gastrin/cholecystokinin type B receptor0101
Proteasome subunit alpha type-60023
D(2) dopamine receptor012114
Calmodulin 0112
Aldehyde oxidase 10101
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10202
Aldehyde oxidase0202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0202
Inositol hexakisphosphate kinase 1110011
D0101
Proteasome subunit beta type-70001
Angiotensin-converting enzyme 2 0134
cytochrome P450 2C9, partial110011
PPM1D protein5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
Trypanothione reductase0101
Inositol monophosphatase 16006
Envelope glycoprotein0033
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Gamma-aminobutyric acid receptor subunit pi0808
Gamma-aminobutyric acid receptor subunit delta0808
Neuronal acetylcholine receptor subunit alpha-41203
Neuronal acetylcholine receptor subunit beta-21203
Gamma-aminobutyric acid receptor subunit beta-10819
Translocator protein0202
Translocator protein0202
Gamma-aminobutyric acid receptor subunit beta-208311
Gamma-aminobutyric acid receptor subunit alpha-40819
Gamma-aminobutyric acid receptor subunit epsilon0808
Gamma-aminobutyric acid receptor subunit alpha-60819
Gamma-aminobutyric acid receptor subunit gamma-10808
Gamma-aminobutyric acid receptor subunit gamma-30808
Gamma-aminobutyric acid receptor subunit theta0808
Beta-1 adrenergic receptor 0124
Alpha-1B adrenergic receptor 0011
cytochrome P450 2C9 precursor7007
Membrane primary amine oxidase 0101
5-hydroxytryptamine receptor 3A0011
Solute carrier family 22 member 30506
Alpha-1A adrenergic receptor0011
Alpha-2B adrenergic receptor0001
Delta-type opioid receptor0518
Alpha-1A adrenergic receptor04410
Alpha-1B adrenergic receptor0237
Mu-type opioid receptor0707
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Alpha-2A adrenergic receptor0101
Nischarin0202
Solute carrier family 22 member 10405
Multidrug and toxin extrusion protein 10707
Nischarin0101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Amyloid-beta precursor protein0202
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Tryptophan 5-hydroxylase 10101
Liver carboxylesterase 10002
Sodium-dependent serotonin transporter09010
Lysosomal Pro-X carboxypeptidase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Leukotriene B4 receptor 10101
Sodium-dependent dopamine transporter0404
Leukotriene B4 receptor 20101
Transporter0707
endonuclease IV6006
PAX80002
pregnane X receptor4004
nuclear receptor subfamily 1, group I, member 24004
nuclear receptor subfamily 0 group B member 10101
flap endonuclease 18008
steroidogenic factor 10101
caspase-1 isoform alpha precursor1001
neuropeptide S receptor isoform A2002
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0003
Tubulin beta-4A chain0225
ATP-dependent translocase ABCB10505
Tubulin beta chain0225
Tubulin alpha-3C chain0225
Serine/threonine-protein kinase pim-10101
ATP-dependent translocase ABCB10505
Tubulin alpha-1B chain0225
Tubulin alpha-4A chain0225
Tubulin beta-4B chain0225
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0225
Tubulin beta-2A chain0225
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0225
Tubulin beta-2B chain0202
Tubulin alpha-3E chain0225
Tubulin alpha-1A chain0225
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
CREB-binding protein1001
Tubulin alpha-1C chain0225
Tubulin beta-6 chain0225
Tubulin beta-2B chain0225
Tubulin beta-1 chain0225
dopamine D1 receptor5005
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0303
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
Dihydrofolate reductase0405
Neuronal acetylcholine receptor subunit alpha-30101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Neuronal acetylcholine receptor subunit beta-40101
Cytochrome P450 2D30101
Taste receptor type 2 member 460011
Cytochrome P450 2D40101
Gamma-aminobutyric acid 0213
Alpha-1-acid glycoprotein 10001
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit gamma-20213
Gamma-aminobutyric acid receptor subunit delta0213
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit alpha-30213
Gamma-aminobutyric acid receptor subunit gamma-30213
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-30213
Neuronal acetylcholine receptor subunit alpha-70202
Gamma-aminobutyric acid receptor subunit alpha-50213
Gamma-aminobutyric acid receptor subunit pi0213
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit theta0213
Gamma-aminobutyric acid receptor subunit gamma-10213
SMAD family member 24004
SMAD family member 34004
STAT3, partial0101
alpha-galactosidase5005
NPC intracellular cholesterol transporter 1 precursor5005
tumor necrosis factor1001
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40102
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
Sodium/potassium-transporting ATPase subunit beta-1 0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1B10101
Solute carrier family 22 member 20203
Multidrug and toxin extrusion protein 20202
15-lipoxygenase, partial3003
polyunsaturated fatty acid lipoxygenase ALOX122002
importin subunit beta-1 isoform 14004
snurportin-14004
GTP-binding nuclear protein Ran isoform 14004
Alpha-synuclein2204
Opioid receptor, delta 1b 0202
Opioid receptor homologue0202
Proenkephalin-B0011
Delta-type opioid receptor0517
Kappa-type opioid receptor0326
Mu-type opioid receptor06110
Kappa-type opioid receptor0416
Kappa-type opioid receptor0404
Mu-type opioid receptor0327
Mu-type opioid receptor0202
Adenylate cyclase 0101
Tyrosine-protein kinase Lck0101
Beta-2 adrenergic receptor0729
Beta-1 adrenergic receptor0729
Thromboxane-A synthase 0202
5-hydroxytryptamine receptor 1B0628
5-hydroxytryptamine receptor 5A0303
huntingtin isoform 21001
Sodium-dependent noradrenaline transporter0202
Cytochrome P450 2C80404
Dipeptidyl peptidase 40202
Acetylcholinesterase0101
Potassium voltage-gated channel subfamily C member 10101
Cytochrome P450 2C190708
Gastrin/cholecystokinin type B receptor 0101
Cytochrome P450 1B10203
Sigma intracellular receptor 20303
Sodium-dependent serotonin transporter0202
Transporter0202
Beta-2 adrenergic receptor0315
Chain A, Dihydrofolate reductase0011
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
acid sphingomyelinase1001
lysosomal alpha-glucosidase preproprotein4004
Thymidylate synthase0303
Thymidylate synthase0101
Dihydrofolate reductase0415
Aldo-keto reductase family 1 member B10303
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0023
transcriptional regulator ERG isoform 33003
histone-lysine N-methyltransferase 2A isoform 2 precursor5005
Histone deacetylase 30101
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Histone deacetylase 40101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Histone deacetylase 10101
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Platelet glycoprotein VI0011
Sodium- and chloride-dependent GABA transporter 20101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
apical membrane antigen 1, AMA12002
transforming acidic coiled-coil-containing protein 30001
Macrophage migration inhibitory factor0202
Metabotropic glutamate receptor 50213
Carbonic anhydrase0103
Carbonic anhydrase0104
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0303
Carbonic anhydrase 0205
Carbonic anhydrase0104
Carbonic anhydrase0205
Carbonic anhydrase 0104
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130203
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Histamine H4 receptor0123
Histamine H3 receptor0101
Carboxylic ester hydrolase 0001
Solute carrier family 22 member 20304
Glycogen synthase kinase-3 alpha0101
Glycogen synthase kinase-3 beta0101
Protein cereblon0202
Epoxide hydrolase 10001
Nitric oxide synthase, brain0101
Nitric oxide synthase, inducible0101
Peptidyl-prolyl cis-trans isomerase FKBP50011
Glutaminyl-peptide cyclotransferase0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Voltage-dependent L-type calcium channel subunit alpha-1C0303
5-hydroxytryptamine receptor 2C 0101
D(2) dopamine receptor0101
Chymotrypsinogen A0101
Potassium voltage-gated channel subfamily E member 10101
Potassium voltage-gated channel subfamily KQT member 10101
chaperonin-containing TCP-1 beta subunit homolog2002
Synaptic vesicle glycoprotein 2A0202
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Catechol O-methyltransferase0101
5-hydroxytryptamine receptor 1E0202
D0101
Sodium-dependent dopamine transporter0101
histone-lysine N-methyltransferase NSD2 isoform 10001
MBT domain-containing protein 10202
Lethal(3)malignant brain tumor-like protein 40202
Lethal(3)malignant brain tumor-like protein 30202
Lethal(3)malignant brain tumor-like protein 10202
nonstructural protein 16006
glycogen synthase kinase-3 beta isoform 10011
Aldo-keto reductase family 1 member B100101
Transient receptor potential cation channel subfamily A member 10011
Transient receptor potential cation channel subfamily M member 20101
Dihydrofolate reductase0505
Beta-lactamase0101
Myc proto-oncogene protein0101
Aldo-keto reductase family 1 member C40101
Malate dehydrogenase, cytoplasmic0101
Aldo-keto reductase family 1 member C30202
Aldo-keto reductase family 1 member C2 0202
Aldo-keto reductase family 1 member C10202
Peroxisome proliferator-activated receptor alpha1001
NACHT, LRR and PYD domains-containing protein 3 0101
Mas-related G-protein coupled receptor member X20033
Aldehyde oxidase 1 0101
Nuclear receptor subfamily 1 group I member 20011
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Glucose-6-phosphate 1-dehydrogenase0202
DNA polymerase III, partial1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Acetylcholinesterase0202
Acyl-CoA desaturase 10101
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Nociceptin receptor0101
Mu-type opioid receptor0101
5-hydroxytryptamine receptor 3E0202
5-hydroxytryptamine receptor 3B0202
5-hydroxytryptamine receptor 3A0202
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
5-hydroxytryptamine receptor 3D0202
5-hydroxytryptamine receptor 3C0202
polyadenylate-binding protein 10101
bcl-2-related protein A10101
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0325
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
Cytochrome P450 1A2 0002
Arylacetamide deacetylase0001
UDP-glucuronosyltransferase 2B10 0101
Arylacetamide deacetylase0001
Arylacetamide deacetylase0001
Lysine-specific histone demethylase 1A0101
Indoleamine 2,3-dioxygenase 10203
Amine oxidase [flavin-containing] B0101
Membrane primary amine oxidase0101
Single-stranded DNA cytosine deaminase1001
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Polyphenol oxidase 20103
Endolysin0011
Cannabinoid receptor 10101
Carbonic anhydrase 0202
Beta-carbonic anhydrase 10202
Carbonic anhydrase0202
Carbonic anhydrase 30202
Chain A, JmjC domain-containing histone demethylation protein 3A1001
rac GTPase-activating protein 1 isoform a0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cannabinoid receptor 10202
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Dihydrofolate reductase 0202
Aldo-keto reductase family 1 member B10101
Parkin1001
Beta-2 adrenergic receptor0204
Beta-3 adrenergic receptor0426
Beta-1 adrenergic receptor0215
Angiotensin-converting enzyme0101
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0202
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
Beta-1 adrenergic receptor0101
Beta-2 adrenergic receptor0101
Sodium/bile acid cotransporter0101
Nuclear receptor subfamily 2 group E member 10022
Pyridoxal kinase0001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Solute carrier family 22 member 70001
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Transcriptional activator protein LuxR0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Tyrosinase0101
NAD(P)H dehydrogenase [quinone] 10001
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0112
Substance-P receptor0213
Neuromedin-K receptor0112
Substance-K receptor0101
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Endothelin-1 receptor0101
Protease 0112
Protein-arginine deiminase type-40202
Carboxypeptidase M0101
5-hydroxytryptamine receptor 1F0213
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 1B0101
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110001
Polyunsaturated fatty acid 5-lipoxygenase0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 20101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
NH(3)-dependent NAD(+) synthetase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Tryptophan 2,3-dioxygenase0102
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100001
Phospholipase A-2-activating protein0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]