Page last updated: 2024-09-28

Anisocoria

Unequal pupil size, which may represent a benign physiologic variant or a manifestation of disease. Pathologic anisocoria reflects an abnormality in the musculature of the iris (IRIS DISEASES) or in the parasympathetic or sympathetic pathways that innervate the pupil. Physiologic anisocoria refers to an asymmetry of pupil diameter, usually less than 2mm, that is not associated with disease.

Synonyms(4)

Synonym
Pupillary Size Inequality
Pupil Diameter Unequal
Anisocoria, Physiologic
Anisocoria

Research Excerpts

Treatment

ExcerptReference
"A case of anisocoria associated with oral pharmacologic treatment of irritable bowel syndrome is reported."( Berman, EL; Nussdorf, JD, 2000)
"At 30 min, miosis and anisocoria were seen in all 15 controls (mean difference between the brimonidine-treated pupil and the control pupil: - 1."( Albrechtsen, SS; Amiri, M; Hassager, C; Jakobsen, EW; Kjaergaard, J; Knudsen, NV; Kondziella, D; Larson, MD; Møller, K; Nersesjan, V; Othman, MH, 2023)

Research

Studies (125)

TimeframeStudies, This Condition (%)All Conditions %
pre-19904 (3.20)23.3326
1990's26 (20.80)12.5806
2000's42 (33.60)18.1394
2010's38 (30.40)28.8240
2020's15 (12.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbamates0low10
salicylic acid0low10
bupropion0low10
hydrogen carbonate0low10
histamine0low10
iodine0low10
methanol0low10
thiamine0low10
ibotenic acid0low10
vanilmandelic acid0low20
homovanillic acid0low20
albuterol0low40
apraclonidine0low110
citalopram0low20
clonidine0low110
erythrosine0low10
fentanyl0low10
fomepizole0low10
gentamicin0low10
p-hydroxyamphetamine0low40
hydroxychloroquine0low10
lidocaine0low20
indomethacin0low10
isoflurane0low10
2-propanol0low230
metformin0low10
mitoxantrone0low10
naphazoline0low10
nortriptyline0low10
oxybutynin0low30
pholedrine0low10
pheniramine0low10
phenobarbital0low10
propofol0low20
sumatriptan0low10
tetracaine0low10
tetraethylammonium0low10
tropicamide0low10
tyramine0low20
prednisolone0low20
prednisone0low20
pilocarpine0medium121
phenylephrine0low40
methacholine chloride0low10
desoxycorticosterone0low10
colchicine0low10
mannitol0low10
cytarabine0low10
valine0low10
phencyclidine0low10
methylprednisolone0low10
quinoxalines0low20
1-naphthylamine0low10
kainic acid0low10
methamphetamine0low10
glycopyrrolate0low80
fluorescein0low10
paclitaxel0low10
etoposide0low10
sufentanil0low10
propiconazole0low40
paroxetine0low30
atracurium0low10
fomesafen0low10
remifentanil0low10
cephalosporin c0low10
sertraline0low20
n-methylscopolamine0low10
methotrexate0low10
moxifloxacin0low10
atropine0low10
cocaine0low140
etomidate0low10
hydromorphone0low10
oxycodone0low10
10-hydroxynortriptyline0low10
butylscopolammonium bromide0low10
brimonidine tartrate0low30
scopolamine hydrobromide0low100
methoxydine0low10
ro13-99040low10
warfarin0low10
acyclovir0low10
dacarbazine0low10
valacyclovir0low10
eye0low60

Protein Targets (953)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE130013
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
RAR-related orphan receptor gamma200020
GLI family zinc finger 3170017
AR protein280028
aldehyde dehydrogenase 1 family, member A1130013
thyroid stimulating hormone receptor120012
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 1, group I, member 3140014
progesterone receptor160016
glucocorticoid receptor [Homo sapiens]230023
retinoic acid nuclear receptor alpha variant 1180018
estrogen-related nuclear receptor alpha240024
pregnane X nuclear receptor180018
estrogen nuclear receptor alpha310031
aryl hydrocarbon receptor9009
thyroid stimulating hormone receptor8008
activating transcription factor 6120012
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
v-jun sarcoma virus 17 oncogene homolog (avian)150015
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
thyroid hormone receptor beta isoform 2190019
nuclear factor erythroid 2-related factor 2 isoform 1160016
cytochrome P450 3A4 isoform 18008
Gamma-aminobutyric acid receptor subunit pi81110
Voltage-dependent calcium channel gamma-2 subunit140014
Gamma-aminobutyric acid receptor subunit beta-181110
Gamma-aminobutyric acid receptor subunit delta81110
Gamma-aminobutyric acid receptor subunit gamma-281110
Glutamate receptor 2143118
Gamma-aminobutyric acid receptor subunit alpha-581110
Gamma-aminobutyric acid receptor subunit alpha-381110
Gamma-aminobutyric acid receptor subunit gamma-181110
Gamma-aminobutyric acid receptor subunit alpha-281110
Gamma-aminobutyric acid receptor subunit alpha-481110
Gamma-aminobutyric acid receptor subunit gamma-381110
Gamma-aminobutyric acid receptor subunit alpha-681110
Gamma-aminobutyric acid receptor subunit alpha-181110
Gamma-aminobutyric acid receptor subunit beta-381110
Gamma-aminobutyric acid receptor subunit beta-281110
Kelch-like ECH-associated protein 10011
GABA theta subunit81110
Gamma-aminobutyric acid receptor subunit epsilon81110
Histone acetyltransferase KAT80101
hypoxia-inducible factor 1 alpha subunit100010
retinoid X nuclear receptor alpha170017
peroxisome proliferator-activated receptor delta9009
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a140014
Histone H2A.x8008
thyroid hormone receptor beta isoform a8008
heat shock protein beta-15005
lamin isoform A-delta10230023
Chain E, Purine nucleoside phosphorylase0101
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
Chain A, Ferritin light chain100010
Thymidine kinase 0101
thioredoxin reductase180018
phosphopantetheinyl transferase120012
GLS protein170017
TDP1 protein250025
Smad35005
EWS/FLI fusion protein160016
arylsulfatase A100010
euchromatic histone-lysine N-methyltransferase 2310031
Bloom syndrome protein isoform 1100010
hemoglobin subunit beta1001
atrial natriuretic peptide receptor 1 precursor4004
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
Solute carrier family 22 member 1 012021
ATP-binding cassette sub-family C member 3022022
Multidrug resistance-associated protein 4022023
Solute carrier family 22 member 60203
Bile salt export pump0404
Bile salt export pump036036
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0102
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0809
Cytochrome P450 2J20505
Disintegrin and metalloproteinase domain-containing protein 171001
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60305
Thymidine kinase 0101
Solute carrier family 22 member 80205
Canalicular multispecific organic anion transporter 1023024
Thymidine kinase0202
glp-1 receptor, partial8008
regulator of G-protein signaling 4110011
NPYLR7B0022
flap endonuclease 18008
peripheral myelin protein 229009
Beta-2 adrenergic receptor0235
Beta-1 adrenergic receptor0033
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
Beta-3 adrenergic receptor0022
Delta-type opioid receptor07310
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
Beta-2 adrenergic receptor 0013
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Beta-2 adrenergic receptor0224
ATP-dependent phosphofructokinase180018
NFKB1 protein, partial5005
muscarinic acetylcholine receptor M1120012
Alpha-2A adrenergic receptor010313
Alpha-2B adrenergic receptor09211
Alpha-2C adrenergic receptor011415
Alpha-2B adrenergic receptor0707
Alpha-1D adrenergic receptor011314
Adenosine receptor A2b0225
Adenosine receptor A2a0328
Alpha-1A adrenergic receptor0448
Alpha-1B adrenergic receptor0347
Amine oxidase [flavin-containing] A 0011
Small conductance calcium-activated potassium channel protein 30112
Chain A, 2-oxoglutarate Oxygenase8008
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta4004
short transient receptor potential channel 6 isoform 10011
5-hydroxytryptamine receptor 4014014
Muscarinic acetylcholine receptor M2022430
Muscarinic acetylcholine receptor M4020123
Muscarinic acetylcholine receptor M109214
Muscarinic acetylcholine receptor M308415
Muscarinic acetylcholine receptor M406211
Muscarinic acetylcholine receptor M506211
Muscarinic acetylcholine receptor M5018121
Muscarinic acetylcholine receptor M209316
Muscarinic acetylcholine receptor M1021328
Muscarinic acetylcholine receptor M10024
Muscarinic acetylcholine receptor M3016119
5-hydroxytryptamine receptor 2C015015
Muscarinic acetylcholine receptor M40113
Histamine H2 receptor71111
5-hydroxytryptamine receptor 70304
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0225
USP1 protein, partial130013
D(1A) dopamine receptor8008
histone acetyltransferase KAT2A isoform 1120012
Acetylcholine receptor subunit alpha0101
Acetylcholine receptor subunit gamma0101
Integrin alpha-50101
Acetylcholine receptor subunit beta0101
UDP-glucuronosyltransferase 2B70304
Neuronal acetylcholine receptor subunit beta-20203
UDP-glucuronosyltransferase 1-60404
Cytochrome P450 2B60103
UDP-glucuronosyltransferase 1A1 0405
UDP-glucuronosyltransferase 1A40303
Sodium-dependent noradrenaline transporter 018321
Sodium-dependent dopamine transporter0808
Neuronal acetylcholine receptor subunit beta-40102
Sodium-dependent serotonin transporter012416
Neuronal acetylcholine receptor subunit alpha-30101
Cytochrome P450 2C190505
UDP-glucuronosyltransferase 2B10 0303
Neuronal acetylcholine receptor subunit alpha-70202
Neuronal acetylcholine receptor subunit alpha-40102
Sodium-dependent dopamine transporter 013215
Acetylcholine receptor subunit delta0101
Chain A, Beta-lactamase130013
cytochrome P450 2D6120012
IDH1110011
chromobox protein homolog 1160016
geminin210021
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
farnesoid X nuclear receptor8008
nuclear receptor ROR-gamma isoform 16006
DNA polymerase kappa isoform 17007
lethal factor (plasmid)3003
Potassium channel subfamily K member 20112
Glycogen phosphorylase, muscle form0101
Renin0101
Carbonic anhydrase 10708
Carbonic anhydrase 207110
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0314
Adenosine receptor A30101
Replicase polyprotein 1ab0314
Amine oxidase [flavin-containing] A0405
Acetylcholinesterase0303
Adenosine receptor A10305
Amine oxidase [flavin-containing] B0405
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A10215
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20204
Guanine deaminase0101
NPC intracellular cholesterol transporter 1 precursor6006
survival motor neuron protein isoform d7007
Sodium-dependent noradrenaline transporter0202
Aldo-keto reductase family 1 member B1014014
Tryptophan 5-hydroxylase 10202
Angiotensin-converting enzyme0808
Aldo-keto reductase family 1 member B10303
5-hydroxytryptamine receptor 1A08311
Aromatase0101
Sodium-dependent serotonin transporter0719
Histamine H1 receptor0729
5-hydroxytryptamine receptor 2B010010
Spike glycoprotein100111
Potassium voltage-gated channel subfamily H member 2018019
Sigma intracellular receptor 20303
Sodium-dependent serotonin transporter0202
Sodium-dependent dopamine transporter0404
Nuclear receptor subfamily 3 group C member 3 0808
Ataxin-2120012
Sigma non-opioid intracellular receptor 1019019
Sigma non-opioid intracellular receptor 10606
Transporter0808
Chain A, Cruzipain3003
acetylcholinesterase6006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)8008
Beta-1 adrenergic receptor 0011
Alpha-1B adrenergic receptor 0022
cytochrome P450 2D6 isoform 16006
cytochrome P450 2C19 precursor5005
cytochrome P450 2C9 precursor4004
Membrane primary amine oxidase 0101
5-hydroxytryptamine receptor 3A0011
Solute carrier family 22 member 30709
5-hydroxytryptamine receptor 1A0325
Alpha-1B adrenergic receptor0303
Alpha-1A adrenergic receptor0123
D0303
D(3) dopamine receptor0303
Alpha-2C adrenergic receptor0606
Alpha-2A adrenergic receptor0606
Alpha-1D adrenergic receptor0303
D(1B) dopamine receptor0202
5-hydroxytryptamine receptor 1B0729
Alpha-2B adrenergic receptor0002
D(4) dopamine receptor0202
Delta-type opioid receptor0518
Alpha-1A adrenergic receptor0415
D(2) dopamine receptor0404
Mu-type opioid receptor0516
Inositol monophosphatase 15005
Alpha-2C adrenergic receptor0002
Alpha-2A adrenergic receptor0002
Alpha-2A adrenergic receptor0101
Nischarin0202
Solute carrier family 22 member 10407
Multidrug and toxin extrusion protein 10808
Nischarin0202
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein1203
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
5-hydroxytryptamine receptor 2C0517
5-hydroxytryptamine receptor 2A0516
Gamma-aminobutyric acid receptor subunit alpha-10325
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20325
Liver carboxylesterase 10001
Gamma-aminobutyric acid receptor subunit beta-30213
5-hydroxytryptamine receptor 1D0336
5-hydroxytryptamine receptor 1F0224
5-hydroxytryptamine receptor 2B0314
5-hydroxytryptamine receptor 60213
Gamma-aminobutyric acid receptor subunit alpha-50112
5-hydroxytryptamine receptor 7 0213
Gamma-aminobutyric acid receptor subunit alpha-30112
5-hydroxytryptamine receptor 5A0213
5-hydroxytryptamine receptor 5B0213
Glutamate receptor ionotropic, NMDA 1 0619
5-hydroxytryptamine receptor 3A0314
Lysosomal Pro-X carboxypeptidase0202
Gamma-aminobutyric acid receptor subunit alpha-20123
Gamma-aminobutyric acid receptor subunit beta-20224
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0619
Glutamate receptor ionotropic, NMDA 2B0619
Glutamate receptor ionotropic, NMDA 2C06110
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60112
Glutamate receptor ionotropic, NMDA 2D0619
5-hydroxytryptamine receptor 4 0213
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0619
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0314
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0619
Gamma-aminobutyric acid receptor subunit theta0101
Luciferase7007
interleukin 83003
endonuclease IV4004
PAX80001
pregnane X receptor4004
ATAD5 protein, partial8008
Fumarate hydratase6006
PPM1D protein6006
Thrombopoietin3003
cytochrome P450 family 3 subfamily A polypeptide 4180018
polyprotein6006
67.9K protein100010
glucocerebrosidase2002
peroxisome proliferator activated receptor gamma120012
vitamin D (1,25- dihydroxyvitamin D3) receptor110011
nuclear receptor subfamily 1, group I, member 26006
nuclear receptor subfamily 0 group B member 10101
cellular tumor antigen p53 isoform a4004
nuclear factor erythroid 2-related factor 2 isoform 2110011
atrial natriuretic peptide receptor 2 precursor5005
ras-related protein Rab-9A7007
steroidogenic factor 10101
muscleblind-like protein 1 isoform 14004
caspase-1 isoform alpha precursor2002
neuropeptide S receptor isoform A3003
Interferon beta150015
Tubulin alpha-1A chain0225
Tubulin beta chain0224
Plasma kallikrein0002
Tubulin beta-4A chain0439
Cellular tumor antigen p53180018
ATP-dependent translocase ABCB10202
Tubulin beta chain0439
ATP-dependent translocase ABCB1010015
Cytochrome P450 3A40808
Tubulin alpha-3C chain0439
Serine/threonine-protein kinase pim-10101
ATP-dependent translocase ABCB10303
Nuclear receptor ROR-gamma3003
Tubulin alpha-1B chain0439
Tubulin alpha-4A chain0439
Tubulin beta-4B chain0439
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain05310
Tubulin beta-2A chain0439
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0439
Tubulin beta-2B chain0316
Tubulin alpha-3E chain0439
Tubulin alpha-1A chain0439
Similar to alpha-tubulin isoform 1 0215
Similar to alpha-tubulin isoform 1 0204
CREB-binding protein1001
ATPase family AAA domain-containing protein 57007
Tubulin alpha-1C chain0439
Tubulin beta-6 chain0439
Tubulin beta-2B chain0439
Tubulin beta-1 chain0439
G8008
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0303
serine/threonine-protein kinase mTOR isoform 16006
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
DNA polymerase iota isoform a (long)100010
transactivating tegument protein VP16 [Human herpesvirus 1]0303
nuclear receptor coactivator 3 isoform a0303
Thymidine kinase 2, mitochondrial0101
HLA class I histocompatibility antigen, B alpha chain 8008
Thymidine kinase0101
Thymidylate synthase0203
Thymidine kinase0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
D(1A) dopamine receptor4004
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Inositol hexakisphosphate kinase 18008
Deoxynucleoside kinase0101
cytochrome P450 2C9, partial8008
Matrix metalloproteinase-90101
Isocitrate lyase0101
SMAD family member 26006
GALC protein3003
SMAD family member 36006
Microtubule-associated protein tau8008
mitogen-activated protein kinase 15005
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Solute carrier family 22 member 30203
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
TAR DNA-binding protein 434105
Solute carrier family 22 member 20406
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90103
Prostaglandin G/H synthase 1 0203
Transient receptor potential cation channel subfamily A member 10011
Dihydrofolate reductase0405
Cytochrome c oxidase subunit 20202
Fatty acid-binding protein, liver0202
Transthyretin0013
Albumin0336
Prostaglandin G/H synthase 10304
Interleukin-80202
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Fatty acid-binding protein, intestinal0101
Aldo-keto reductase family 1 member B10303
Prostaglandin G/H synthase 10404
Sodium- and chloride-dependent GABA transporter 10303
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
Prostaglandin G/H synthase 20516
Prostaglandin G/H synthase 2 0202
UDP-glucuronosyltransferase 1A30001
Sodium- and chloride-dependent betaine transporter0303
Prostaglandin G/H synthase 20303
Prostaglandin G/H synthase 20203
Carbonic anhydrase 90203
Prostaglandin G/H synthase 1 0202
Carbonic anhydrase 40102
P2Y purinoceptor 120202
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Genome polyprotein 0213
chaperonin-containing TCP-1 beta subunit homolog2002
thioredoxin glutathione reductase4004
hypothetical protein, conserved2002
bromodomain adjacent to zinc finger domain 2B5005
thyrotropin-releasing hormone receptor3003
vitamin D3 receptor isoform VDRA9009
eyes absent homolog 2 isoform a1001
lethal(3)malignant brain tumor-like protein 1 isoform I3003
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
Acetylcholine receptor subunit alpha0101
Acetylcholine receptor subunit beta0101
Acetylcholine receptor subunit gamma0101
Acetylcholine receptor subunit delta0101
Acetylcholine receptor subunit delta0101
Acetylcholine receptor subunit alpha0101
Acetylcholine receptor subunit gamma0101
Acetylcholine receptor subunit beta0101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
Prothrombin0001
Regulatory protein E20011
DNA topoisomerase 10102
DNA topoisomerase 2-alpha02110
Polyunsaturated fatty acid lipoxygenase ALOX150303
DNA topoisomerase 20002
Serum paraoxonase/arylesterase 10303
Caspase-30101
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta0119
Integrase 0202
Solute carrier organic anion transporter family member 1B30809
potassium voltage-gated channel subfamily H member 2 isoform d3003
Nuclear receptor subfamily 1 group I member 20022
D(2) dopamine receptor0303
D(4) dopamine receptor0101
Mu-type opioid receptor010313
Kappa-type opioid receptor0527
Mu-type opioid receptor06512
D(3) dopamine receptor0505
Delta-type opioid receptor07210
Kappa-type opioid receptor0516
Kappa-type opioid receptor05410
Mu-type opioid receptor0215
Sigma non-opioid intracellular receptor 10505
Alcohol dehydrogenase E chain0112
Alcohol dehydrogenase S chain0112
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
apical membrane antigen 1, AMA12002
transforming acidic coiled-coil-containing protein 30001
Solute carrier family 22 member 20305
Carbonic anhydrase 120102
Carbonic anhydrase 30102
Macrophage migration inhibitory factor0202
Carbonic anhydrase 40203
Carbonic anhydrase 60203
Histamine H2 receptor0325
5-hydroxytryptamine receptor 1D0215
Histamine H1 receptor0134
Histamine H1 receptor0314
Metabotropic glutamate receptor 50112
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase0102
Carbonic anhydrase 70102
Carbonic anhydrase0002
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 0002
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0002
Carbonic anhydrase0002
Carbonic anhydrase 0002
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 150203
Carbonic anhydrase 130102
Histamine H4 receptor0123
Histamine H3 receptor0101
Carboxylic ester hydrolase 0001
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
Histamine H3 receptor0123
ClpP2002
lysosomal alpha-glucosidase preproprotein1001
M-phase phosphoprotein 85005
Solute carrier family 22 member 80001
Spike glycoprotein0011
Replicase polyprotein 1ab0112
Transmembrane protease serine 20011
Procathepsin L0112
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Angiotensin-converting enzyme 2 0011
Toll-like receptor 90101
Toll-like receptor 70101
dopamine D1 receptor6006
Glutamate receptor 10314
Glutamate receptor 30314
Glutamate receptor 40314
Glutamate receptor ionotropic, kainate 10314
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 50112
Glutamate receptor ionotropic, kainate 20325
Glutamate receptor ionotropic, kainate 30303
Glutamate receptor ionotropic, kainate 40303
Metabotropic glutamate receptor 10101
Metabotropic glutamate receptor 20112
Metabotropic glutamate receptor 40112
Glutamate receptor ionotropic, kainate 50303
Chain A, membrane-associated prostaglandin E synthase-20101
Parkin2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)5005
peripheral myelin protein 22 isoform 11001
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Epidermal growth factor receptor0303
Phospholipase A2, major isoenzyme0101
Neuronal acetylcholine receptor subunit alpha-40101
Androgen receptor0213
Neuronal acetylcholine receptor subunit beta-20101
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Thromboxane-A synthase 0101
Indoleamine 2,3-dioxygenase 10101
Caspase-10001
Nitric oxide synthase, inducible0101
Substance-P receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0203
Bifunctional epoxide hydrolase 20101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G3003
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 70002
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Dehydrogenase/reductase SDR family member 90101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10404
histone deacetylase 9 isoform 31001
Chain A, Glutamate receptor 20011
Chain A, Glutamate receptor 20011
Chain C, Glutamate receptor 20011
Chain A, JmjC domain-containing histone demethylation protein 3A3003
importin subunit beta-1 isoform 13003
snurportin-13003
Metabotropic glutamate receptor 60011
Glutamate receptor ionotropic, kainate 10213
Glutamate receptor 10112
Glutamate receptor 20112
Glutamate receptor 30011
Glutamate receptor 40101
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor ionotropic, kainate 30202
Glutamate receptor ionotropic, kainate 40101
Glutamate receptor ionotropic, kainate 50202
CAAX prenyl protease 2 isoform 20001
streptokinase A precursor0011
Fatty-acid amide hydrolase 10202
DNA gyrase subunit A0203
DNA primase0101
Potassium channel subfamily K member 30202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0303
Sodium channel protein type 9 subunit alpha0303
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0303
Dipeptidyl peptidase 40101
galanin receptor type 30101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] B0101
Synaptic vesicular amine transporter0101
Trace amine-associated receptor 10011
Trace amine-associated receptor 10022
Trace amine-associated receptor 10033
Trace amine-associated receptor 10022
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
15-lipoxygenase, partial2002
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 33003
DNA polymerase eta isoform 12002
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10112
Thymidylate synthase0202
Integrin beta-33104
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Integrin alpha-IIb3003
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, NMDA 2B0303
nonstructural protein 13003
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Androgen receptor0303
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Chain A, Probable serine/threonine-protein kinase pknB0101
WRN1001
DNA polymerase III, partial1001
nonstructural protein 10101
LANA0001
pyruvate kinase1001
phospholipase A2, group III0101
interferon gamma precursor0001
histone-lysine N-methyltransferase NSD2 isoform 10001
huntingtin isoform 22002
protein AF-9 isoform a0001
tyrosine-protein kinase Yes1001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
GTP-binding nuclear protein Ran isoform 11001
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
Vpr1001
DNA repair protein RAD52 homolog isoform a0001
pyruvate kinase PKM isoform b1001
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Voltage-dependent L-type calcium channel subunit alpha-1F0314
Glycoprotein hormones alpha chain1001
Receptor tyrosine-protein kinase erbB-20202
Tyrosine-protein kinase Fyn0202
Proto-oncogene tyrosine-protein kinase ROS0101
Ornithine decarboxylase1001
Cytochrome P450 2D60606
Casein kinase II subunit alpha'0101
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0314
Tyrosine-protein kinase BTK0101
NEDD8-activating enzyme E1 regulatory subunit0011
Voltage-dependent L-type calcium channel subunit alpha-1S0314
Voltage-dependent L-type calcium channel subunit alpha-1C0314
Multidrug and toxin extrusion protein 20101
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
Single-stranded DNA cytosine deaminase1001
P2Y purinoceptor 120101
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
DNA gyrase subunit B0101
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA topoisomerase 4 subunit A0101
DNA gyrase subunit B0101
Potassium voltage-gated channel subfamily E member 10101
DNA gyrase subunit A0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
DNA gyrase subunit B0102
POU domain, class 2, transcription factor 10002
Muscarinic acetylcholine receptor 0011
Muscarinic acetylcholine receptor 0101
Kappa-type opioid receptor0114
UDP-glucuronosyltransferase 1A80002
Cytochrome P450 2C80101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
D(1A) dopamine receptor0304
5-hydroxytryptamine receptor 2A0808
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
5-hydroxytryptamine receptor 60202
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Cytochrome P450 2D40101
MBT domain-containing protein 10101
Lethal(3)malignant brain tumor-like protein 40101
Lethal(3)malignant brain tumor-like protein 30101
Lethal(3)malignant brain tumor-like protein 10101
Acetylcholinesterase0101
Beta-secretase 10123
Genome polyprotein 0101
Integrin alpha-V 0101
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
Fibroblast growth factor receptor 10101
Proto-oncogene tyrosine-protein kinase Src0101
Substance-K receptor0202
Cholecystokinin receptor type A0202
Melanocortin receptor 50404
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Beta-tubulin 0101
Nucleotide-binding oligomerization domain-containing protein 20101
Myeloperoxidase0101
Quinolone resistance protein NorA0101
Beta-adrenergic receptor kinase 10101
Potassium voltage-gated channel subfamily A member 30101
Beta-adrenergic receptor kinase 10112
Substance-P receptor0101
Rhodopsin kinase GRK10101
G protein-coupled receptor kinase 50101
G protein-coupled receptor kinase 50101
P2X purinoceptor 40101
Envelope glycoprotein0022
Rhodopsin kinase GRK10101
P2X purinoceptor 40101
Beta-adrenergic receptor kinase 10001
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0202
Beta-1 adrenergic receptor0101
Alpha-1B adrenergic receptor0101
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0202
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20103
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Rap guanine nucleotide exchange factor 31001
Transcriptional activator protein LuxR0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 3B0101
Carboxypeptidase M0101
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 1E0101
5-hydroxytryptamine receptor 1F0213
5-hydroxytryptamine receptor 70101
5-hydroxytryptamine receptor 3A0112
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
5-hydroxytryptamine receptor 1B0101
cGMP-gated cation channel alpha-10011
Sodium channel protein type 7 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Solute carrier family 22 member 10203
Solute carrier family 22 member 20102
Solute carrier family 22 member 50001
Potassium voltage-gated channel subfamily A member 10101
Solute carrier family 22 member 40001
Solute carrier family 22 member 40101
Solute carrier family 22 member 30001
Solute carrier family 22 member 50001
Solute carrier family 22 member 40001
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Protein Rev 0011
guanine nucleotide-binding protein subunit alpha-150112
D(3) dopamine receptor isoform e1001
trace amine-associated receptor 10112
Phenylethanolamine N-methyltransferase0101
Dopamine beta-hydroxylase 0001
Histamine H3 receptor0001
Solute carrier family 15 member 10203
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Valacyclovir hydrolase0001
Chain A, Arginase 10101
Large neutral amino acids transporter small subunit 10101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]