Page last updated: 2024-09-27

Optic Atrophy, Hereditary, Leber

A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))

Synonyms(1)

Synonym
Optic Atrophy, Hereditary, Leber

Research

Studies (209)

TimeframeStudies, This Condition (%)All Conditions %
pre-19908 (3.83)23.3326
1990's0 (0.00)12.5806
2000's80 (38.28)18.1394
2010's82 (39.23)28.8240
2020's39 (18.66)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low30
choline0low10
citric acid, anhydrous0low10
methylmalonic acid0low10
creatine0low10
cytosine0low10
lactic acid0low10
glycine0low20
niacinamide0low10
nitrites0low10
succinic acid0low20
taurine0low10
toluene0low10
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid0low10
4-aminopyridine0low10
metronidazole0low10
mitoxantrone0low10
papaverine0low10
pentoxifylline0low10
propofol0low10
risperidone0low10
sulthiame0low10
zolpidem0low10
prednisolone0medium21
sorbitol0low10
prednisone0low10
alanine0low30
lysine0low10
cyanides0low10
galactose0low50
tyrosine0low10
leucine0low10
valine0low10
tryptophan0low10
tert-butylhydroperoxide0low10
isoprene0low10
methylprednisolone0low40
rotenone0low170
quinoxalines0medium22
4-phenylenediamine0low10
2-methylpentane0low10
2,5-hexanedione0low10
n-hexane0low10
thiazoles0low10
citrulline0low10
malondialdehyde0low10
acetylcysteine0low10
ethambutol0low50
paraquat0low10
2-amino-3-chloro-1,4-naphthoquinone0low10
gadolinium0low10
zalcitabine0low10
glutamic acid0low60
epirubicin0low10
propiconazole0low20
thiazolyl blue0low10
glutathione disulfide0low10
homocysteine0low10
mafosfamide0low10
deoxyglucose0low10
tadalafil0low10
4-hydroxy-25-desoxyneorollinicin0low10
3-nitrotyrosine0low10
hexacyanoferrate iii0low10
tretinoin0low10
retinol0low20
cocaine0low10
thapsigargin0low10
riboflavin0low20
isomethyleugenol0low10
retinaldehyde0low40
retinol acetate0low20
capsaicin0low10
D-fructopyranose0low10
naphthoquinones0low10
11-cis-retinal0low20
coenzyme q100medium61
sirolimus0low10
topiramate0low10
geldanamycin0low10
enalapril0low10
3,3'-dioctadecylindocarbocyanine0low10
carbocyanines0low10
9-cis-retinal0low10
bafilomycin a10low10
piericidin a0low10
sun n80750low10
ubiquinol0low10
brimonidine tartrate0medium22
ru 666470low10
nad0low20
cytochrome c-t0low20
oligonucleotides0low10
ubiquinone0medium556
sodium ethylxanthate0low10
alpha-tocotrienol quinone0low30
ascorbic acid0low20
minocycline0low10
epidermal growth factor0low10
phytoestrogens0low10
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone0low20
vitamin b 120low40
cyclosporine0medium21
deoxyguanosine0low10
guanine0low20
8-hydroxy-2'-deoxyguanosine0low10
eye0low120

Protein Targets (1,258)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Retinaldehyde-binding protein 10011
Chain A, Retinaldehyde-binding protein 10011
Chain A, JmjC domain-containing histone demethylation protein 3A7007
glp-1 receptor, partial5005
thioredoxin reductase140014
USP1 protein, partial140014
TDP1 protein260026
Smad35005
67.9K protein8008
IDH19009
nuclear factor erythroid 2-related factor 2 isoform 29009
flap endonuclease 17007
geminin170017
Vpr2002
Glycoprotein hormones alpha chain3003
Guanine nucleotide-binding protein G6006
retinoic acid nuclear receptor alpha variant 1260026
retinoid X nuclear receptor alpha180018
estrogen-related nuclear receptor alpha300030
pregnane X nuclear receptor220022
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE160016
RAR-related orphan receptor gamma240024
aldehyde dehydrogenase 1 family, member A1160016
thyroid stimulating hormone receptor120012
Nuclear receptor ROR-gamma5117
ORF730011
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
phosphopantetheinyl transferase110011
bromodomain adjacent to zinc finger domain 2B5005
euchromatic histone-lysine N-methyltransferase 2220022
pyruvate kinase PKM isoform a1001
Tubulin--tyrosine ligase0202
Chain A, Cruzipain6006
Microtubule-associated protein tau130013
thyroid stimulating hormone receptor110011
estrogen receptor 2 (ER beta)150015
cytochrome P450 family 3 subfamily A polypeptide 4160016
glucocorticoid receptor [Homo sapiens]230023
cytochrome P450 2D69009
glucocerebrosidase3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
cytochrome P450 2D6 isoform 14004
chromobox protein homolog 1140014
transcriptional regulator ERG isoform 33003
thyroid hormone receptor beta isoform 2170017
mitogen-activated protein kinase 1100010
peripheral myelin protein 22160016
survival motor neuron protein isoform d100010
lethal factor (plasmid)6006
lamin isoform A-delta10200020
Potassium channel subfamily K member 20011
Rap guanine nucleotide exchange factor 31001
Cellular tumor antigen p53180018
Potassium voltage-gated channel subfamily A member 30011
Acetylcholinesterase0202
Pteridine reductase 10202
Potassium voltage-gated channel subfamily A member 10202
Potassium voltage-gated channel subfamily H member 20808
ATP-dependent phosphofructokinase110011
Luciferase8008
acetylcholinesterase120012
GLI family zinc finger 3220022
AR protein270027
nuclear receptor subfamily 1, group I, member 3210021
progesterone receptor140014
farnesoid X nuclear receptor150015
estrogen nuclear receptor alpha340034
G8008
aryl hydrocarbon receptor120012
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
nuclear receptor subfamily 1, group I, member 23003
Histone H2A.x8008
vitamin D3 receptor isoform VDRA100010
histone deacetylase 9 isoform 31001
nuclear factor erythroid 2-related factor 2 isoform 1170017
DNA polymerase kappa isoform 18008
Voltage-dependent calcium channel gamma-2 subunit120012
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 8008
Glutamate receptor 2124218
Inositol hexakisphosphate kinase 18008
ATPase family AAA domain-containing protein 5110011
Ataxin-2150015
cytochrome P450 2C9, partial8008
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Aldo-keto reductase family 1 member B100004
Aldo-keto reductase family 1 member B10002
Chain A, 2-oxoglutarate Oxygenase6006
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
dopamine D1 receptor4004
15-lipoxygenase, partial8008
pregnane X receptor8008
NFKB1 protein, partial5005
Thrombopoietin3003
regulator of G-protein signaling 48008
vitamin D (1,25- dihydroxyvitamin D3) receptor170017
arylsulfatase A7007
Bloom syndrome protein isoform 19009
D(1A) dopamine receptor3003
thyroid hormone receptor beta isoform a9009
heat shock protein beta-1110011
muscarinic acetylcholine receptor M17007
Histone deacetylase 30101
Solute carrier family 22 member 60101
Histone deacetylase 40101
Histone deacetylase 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
importin subunit beta-1 isoform 16006
snurportin-16006
tumor susceptibility gene 101 protein2002
GTP-binding nuclear protein Ran isoform 14004
Bile salt export pump015015
Cyclin-dependent kinase 10112
Heat shock protein HSP 90-beta0101
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 434105
Protein mono-ADP-ribosyltransferase PARP150303
Leucine-rich repeat serine/threonine-protein kinase 20202
Chain A, TYROSYL-DNA PHOSPHODIESTERASE9009
Carbonic anhydrase 106012
Carbonic anhydrase 206214
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 08212
Proton-coupled amino acid transporter 10506
Adenosine deaminase0001
Carbonic anhydrase 40203
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Integrin beta-35117
Integrin alpha-IIb5117
Glutamate receptor 10426
Glutamate receptor 30426
Glutamate receptor 40426
Glutamate receptor ionotropic, kainate 10415
Glutamate receptor 10112
Glutamate receptor 20101
Glutamate receptor ionotropic, kainate 10314
Glutamate receptor ionotropic, kainate 20415
Glutamate receptor 10426
Glutamate receptor 20426
Glutamate receptor 30314
Glutamate receptor ionotropic, kainate 30303
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor 40415
Glutamate receptor ionotropic, NMDA 2A 07211
Glutamate receptor ionotropic, NMDA 2B08212
Glutamate receptor ionotropic, NMDA 2C07211
Glutamate receptor ionotropic, kainate 40303
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, kainate 20314
Glutamate receptor ionotropic, kainate 30202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, kainate 40101
Glutamate receptor ionotropic, kainate 50202
Glutamate receptor ionotropic, NMDA 2D07211
Glutamate receptor ionotropic, kainate 50303
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B07211
Glutamate receptor ionotropic, NMDA 3A07211
Glutamate receptor 40101
Glutamate receptor 30101
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase5005
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Polyphenol oxidase 20102
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0213
Spike glycoprotein110011
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10113
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Adenosine receptor A30303
P2X purinoceptor 30101
V-type proton ATPase subunit S10101
Vacuolar proton pump subunit B 0101
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
GLS protein100010
peroxisome proliferator-activated receptor delta120012
peroxisome proliferator activated receptor gamma130013
DNA polymerase iota isoform a (long)9009
nuclear receptor ROR-gamma isoform 1100010
cytochrome P450 3A4 isoform 1110011
transient receptor potential cation channel subfamily V member 11001
Gamma-aminobutyric acid receptor subunit pi113115
Transient receptor potential cation channel subfamily V member 10213
Lysine-specific histone demethylase 1A0101
NADH-ubiquinone oxidoreductase chain 10303
Cytochrome P450 1A20112
Polyunsaturated fatty acid 5-lipoxygenase0303
Gamma-aminobutyric acid receptor subunit beta-1113115
Gamma-aminobutyric acid receptor subunit delta113115
Gamma-aminobutyric acid receptor subunit gamma-2113115
Gamma-aminobutyric acid receptor subunit alpha-5113115
Gamma-aminobutyric acid receptor subunit alpha-3113115
Cannabinoid receptor 10101
Acetylcholinesterase0505
Prostaglandin G/H synthase 10202
Gamma-aminobutyric acid receptor subunit gamma-1113115
Gamma-aminobutyric acid receptor subunit alpha-2113115
Gamma-aminobutyric acid receptor subunit alpha-4113115
Gamma-aminobutyric acid receptor subunit gamma-3113115
Gamma-aminobutyric acid receptor subunit alpha-6113115
Cannabinoid receptor 2 0101
D(2) dopamine receptor0516
Gamma-aminobutyric acid receptor subunit alpha-1113115
Gamma-aminobutyric acid receptor subunit beta-3113115
Gamma-aminobutyric acid receptor subunit beta-2113115
Inositol monophosphatase 16006
Corticotropin-releasing factor receptor 20101
Transient receptor potential cation channel subfamily V member 10214
GABA theta subunit113115
Transient receptor potential cation channel subfamily V member 40011
Gamma-aminobutyric acid receptor subunit epsilon113115
Transient receptor potential cation channel subfamily V member 20011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70303
Solute carrier family 22 member 10102
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0112
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0102
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0303
Alpha-ketoglutarate-dependent dioxygenase FTO0202
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10202
General amino-acid permease GAP10001
Nitric oxide synthase, brain0101
Nitric oxide synthase, brain 0101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein1405
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10101
5-hydroxytryptamine receptor 2C0506
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0505
Gamma-aminobutyric acid receptor subunit alpha-10325
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20325
D0202
5-hydroxytryptamine receptor 1A0404
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Liver carboxylesterase 10001
Sodium-dependent noradrenaline transporter 0606
Sodium-dependent dopamine transporter0314
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0404
Gamma-aminobutyric acid receptor subunit beta-30314
5-hydroxytryptamine receptor 1B0303
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50224
Sodium-dependent serotonin transporter0303
Sodium-dependent serotonin transporter0203
5-hydroxytryptamine receptor 7 0202
Gamma-aminobutyric acid receptor subunit alpha-30224
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20224
Gamma-aminobutyric acid receptor subunit beta-20224
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit epsilon0101
Sodium-dependent dopamine transporter 0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0404
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60213
Sodium-dependent dopamine transporter0202
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Sigma non-opioid intracellular receptor 10202
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0303
Sodium- and chloride-dependent creatine transporter 10101
Carbonic anhydrase 40408
Carbonic anhydrase0305
Carbonic anhydrase 150406
Deoxycytidine kinase0001
Thymidine kinase, cytosolic0102
Deoxycytidine kinase0113
AAA family ATPase 0001
Sterol O-acyltransferase 10101
endonuclease IV2002
histone acetyltransferase KAT2A isoform 17007
Angiotensin-converting enzyme 0101
Angiotensin-converting enzyme0505
Type-2 angiotensin II receptor0101
Succinyl-diaminopimelate desuccinylase0101
Solute carrier family 15 member 10101
Solute carrier organic anion transporter family member 1A10001
Angiotensin-converting enzyme0101
Solute carrier family 15 member 10101
Multidrug and toxin extrusion protein 10303
Angiotensin-converting enzyme 2 0101
Genome polyprotein 0101
Fumarate hydratase5005
PPM1D protein6006
EWS/FLI fusion protein110011
polyprotein5005
Tyrosine-protein kinase Fyn0213
UDP-glucuronosyltransferase 2B70001
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Pantothenate synthetase0101
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Metabotropic glutamate receptor 50113
Metabotropic glutamate receptor 80011
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10303
Glutamate carboxypeptidase 20101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Carbonic anhydrase-like protein, putative0003
Glutamate racemase0001
Glutathione reductase0001
Multidrug resistance-associated protein 1 0103
Histone-lysine N-methyltransferase EHMT20101
Histone-lysine N-methyltransferase EHMT10101
Glycine receptor subunit alpha-10022
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10505
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0001
Chain A, Beta-lactamase5005
Chain A, Ferritin light chain8008
hypoxia-inducible factor 1 alpha subunit8008
v-jun sarcoma virus 17 oncogene homolog (avian)110011
huntingtin isoform 22002
Cytochrome P450 3A40516
Cytochrome P450 2D60314
Cytochrome P450 2C9 0415
Cytochrome P450 2C190516
NAD-dependent protein deacetylase sirtuin-20202
NAD-dependent protein deacetylase 0202
interleukin 84004
cellular tumor antigen p53 isoform a5005
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
potassium voltage-gated channel subfamily H member 2 isoform d5005
Cationic amino acid transporter 30101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
ATAD5 protein, partial5005
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX123003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
DNA polymerase beta2002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
DNA polymerase eta isoform 12002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
M-phase phosphoprotein 85005
muscleblind-like protein 1 isoform 14004
caspase-1 isoform alpha precursor2002
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012013
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10022
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20022
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0303
Mu-type opioid receptor0303
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-72002
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
Canalicular multispecific organic anion transporter 1012012
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30405
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40303
Broad substrate specificity ATP-binding cassette transporter ABCG20204
Serine racemase0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
nonstructural protein 14004
Nuclear receptor subfamily 1 group I member 20022
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Androgen receptor0303
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Lanosterol 14-alpha demethylase0101
Albumin0033
Stromelysin-10202
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Cytochrome P450 2J20202
Chain A, Probable serine/threonine-protein kinase pknB0101
WRN1001
apical membrane antigen 1, AMA11001
DNA polymerase III, partial2002
hypothetical protein, conserved1001
nonstructural protein 10101
LANA0001
Parkin3003
pyruvate kinase1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
phospholipase A2, group III0101
NPC intracellular cholesterol transporter 1 precursor3003
interferon gamma precursor0001
atrial natriuretic peptide receptor 1 precursor4004
histone-lysine N-methyltransferase NSD2 isoform 10001
atrial natriuretic peptide receptor 2 precursor4004
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
ras-related protein Rab-9A4004
protein AF-9 isoform a0001
serine/threonine-protein kinase mTOR isoform 13003
tyrosine-protein kinase Yes1001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
DNA repair protein RAD52 homolog isoform a0001
pyruvate kinase PKM isoform b1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
5-hydroxytryptamine receptor 40606
Solute carrier family 22 member 30101
Epidermal growth factor receptor0112
Receptor tyrosine-protein kinase erbB-20101
Aldo-keto reductase family 1 member B10404
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40303
ATP-dependent translocase ABCB10203
Proto-oncogene tyrosine-protein kinase ROS0101
Ornithine decarboxylase1002
Muscarinic acetylcholine receptor M10303
DNA topoisomerase 2-alpha0113
Polyunsaturated fatty acid lipoxygenase ALOX150202
DNA topoisomerase 20001
Casein kinase II subunit alpha'0112
5-hydroxytryptamine receptor 2C0606
Histamine H2 receptor4004
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
DNA topoisomerase 2-beta0012
Tyrosine-protein kinase BTK0112
NEDD8-activating enzyme E1 regulatory subunit0011
Nuclear receptor subfamily 3 group C member 3 0404
Integrase 0101
Multidrug and toxin extrusion protein 20202
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
Single-stranded DNA cytosine deaminase1001
P2Y purinoceptor 120101
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain A, NAD-dependent deacetylase0101
activating transcription factor 66006
Caspase-75005
caspase-35005
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
hexokinase-4 isoform 11001
cytochrome P450 2C19 precursor4004
cytochrome P450 2C9 precursor2002
glucokinase regulatory protein1001
cGMP-dependent 3',5'-cyclic phosphodiesterase0303
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0303
cGMP-specific 3',5'-cyclic phosphodiesterase0415
3',5'-cyclic-AMP phosphodiesterase 0101
Vascular endothelial growth factor receptor 1 0101
Serine hydroxymethyltransferase, mitochondrial0101
Vascular endothelial growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0202
Disintegrin and metalloproteinase domain-containing protein 173003
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0303
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0404
CREB-binding protein1001
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 0202
Phosphodiesterase 0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0203
Photosystem I iron-sulfur center 0001
peripheral myelin protein 22 isoform 14004
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
Tumor necrosis factor0101
Cholinesterase0101
Adenosine receptor A2b0101
Chitotriosidase-10213
Endochitinase B10213
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial0202
Acyl carrier protein, mitochondrial0202
Peroxiredoxin-10011
Oxysterols receptor LXR-alpha0011
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0112
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
SMAD family member 26006
SMAD family member 36006
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
5-hydroxytryptamine receptor 2B0606
Sodium- and chloride-dependent betaine transporter0101
UDP-glucuronosyltransferase 1A80001
Chain A, Cellular retinoic acid-binding protein 20011
Chain A, Cellular retinoic acid-binding protein 20011
Alpha-synuclein1304
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Solute carrier organic anion transporter family member 1B10303
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
NPYLR7B0011
thyrotropin-releasing hormone receptor2002
tumor necrosis factor1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
Riboflavin-binding protein0112
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Albumin0011
5-hydroxytryptamine receptor 1A0123
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0202
D(2) dopamine receptor0202
Alpha-1B adrenergic receptor0303
Beta-1 adrenergic receptor0101
Alpha-2C adrenergic receptor0202
D(3) dopamine receptor0101
Muscarinic acetylcholine receptor M30202
D(1A) dopamine receptor0202
D(4) dopamine receptor0101
Alpha-1D adrenergic receptor0202
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Alpha-1A adrenergic receptor0202
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0202
Alpha-1B adrenergic receptor0101
D(3) dopamine receptor0202
Alpha-1A adrenergic receptor0303
5-hydroxytryptamine receptor 60303
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0101
5-hydroxytryptamine receptor 2B0101
Sodium channel protein type 5 subunit alpha0202
Transporter0101
5-hydroxytryptamine receptor 1A0101
Histamine H3 receptor0101
neuropeptide S receptor isoform A1001
Pancreatic triacylglycerol lipase0101
Dihydroorotate dehydrogenase (fumarate)0101
D(1A) dopamine receptor2002
Dihydroorotate dehydrogenase 0101
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10213
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10112
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0112
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Chain A, Protein (aspartate Aminotransferase)0011
Chain A, Aspartate Aminotransferase0011
Lysine-specific demethylase 4E0101
Delta-aminolevulinic acid dehydratase0101
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
NADP-dependent malic enzyme, mitochondrial0001
Solute carrier family 13 member 30101
Methyl-accepting chemotaxis protein NahY0011
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0202
Carbonic anhydrase 0202
Carbonic anhydrase 0202
Carbonic anhydrase0202
Carbonic anhydrase 120206
Carbonic anhydrase 30204
Carbonic anhydrase 60206
Delta-type opioid receptor0202
Carbonic anhydrase 5A, mitochondrial0217
Carbonic anhydrase 70206
Carbonic anhydrase0204
Mu-type opioid receptor0202
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20202
Carbonic anhydrase 90206
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase0204
Carbonic anhydrase 0202
Delta carbonic anhydrase0202
Carbonic anhydrase 130202
Carbonic anhydrase 130104
Carbonic anhydrase 140206
Carbonic anhydrase 5B, mitochondrial0206
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Phosphodiesterase 0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
cGMP-specific 3',5'-cyclic phosphodiesterase0112
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cystic fibrosis transmembrane conductance regulator0011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
Potassium voltage-gated channel subfamily E member 10101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Potassium voltage-gated channel subfamily KQT member 10101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Synaptic vesicular amine transporter0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
Nuclear receptor subfamily 2 group E member 10011
GALC protein2002
Sodium- and chloride-dependent taurine transporter0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0101
Endolysin0011
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 0001
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110001
Sodium channel protein type 2 subunit alpha0101
Cytochrome P450 2C80101
Arachidonate 5-lipoxygenase-activating protein0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 20101
Carbonic anhydrase 0101
Carbonic anhydrase 0103
Carbonic anhydrase0103
Carbonic anhydrase 0103
Chain A, Nuclear Receptor ROR-beta0101
Ornithine decarboxylase0001
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Plasma kallikrein0002
Myeloperoxidase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
SLC16A10 protein0002
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100002
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Adenosine receptor A10001
Adenosine receptor A2a0001
Taste receptor type 2 member 140001
Chain A, Arginase 10101
C-X-C chemokine receptor type 40011
Solute carrier family 22 member 70001
Reverse transcriptase/RNaseH 0113
Translocator protein0101
Sphingosine-1-phosphate lyase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]