sulthiame has been researched along with Optic Atrophy, Hereditary, Leber in 1 studies
sulthiame: was heading 1964-94 (see under THIAZINES 1964-90); use THIAZINES to search SULTHIAME 1966-94
Optic Atrophy, Hereditary, Leber: A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reinert, MC | 1 |
| Pacheu-Grau, D | 1 |
| Catarino, CB | 1 |
| Klopstock, T | 1 |
| Ohlenbusch, A | 1 |
| Schittkowski, M | 1 |
| Wilichowski, E | 1 |
| Rehling, P | 1 |
| Brockmann, K | 1 |
1 other study available for sulthiame and Optic Atrophy, Hereditary, Leber
| Article | Year |
|---|---|
Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy.
Topics: Child; DNA, Mitochondrial; Female; Humans; Male; Mitochondria; Mutation; Optic Atrophy, Hereditary, | 2021 |