alanine has been researched along with Optic Atrophy, Hereditary, Leber in 3 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Optic Atrophy, Hereditary, Leber: A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fuller, JT | 1 |
| Barnes, S | 1 |
| Sadun, LA | 1 |
| Ajmera, P | 1 |
| Alexandrova, AN | 1 |
| Sadun, AA | 1 |
| Ji, Y | 1 |
| Jia, X | 1 |
| Li, S | 1 |
| Xiao, X | 1 |
| Guo, X | 1 |
| Zhang, Q | 1 |
| Kaplanová, V | 1 |
| Zeman, J | 1 |
| Hansíková, H | 1 |
| Cerná, L | 1 |
| Houst'ková, H | 1 |
| Misovicová, N | 1 |
| Houstek, J | 1 |
3 other studies available for alanine and Optic Atrophy, Hereditary, Leber
| Article | Year |
|---|---|
Coenzyme Q10 trapping in mitochondrial complex I underlies Leber's hereditary optic neuropathy.
Topics: Alanine; Electron Transport Complex I; Humans; Optic Atrophy, Hereditary, Leber; Reactive Oxygen Spe | 2023 |
Evaluation of the X-linked modifier loci for Leber hereditary optic neuropathy with the G11778A mutation in Chinese.
Topics: Alanine; Amino Acid Substitution; Asian People; Case-Control Studies; China; Chromosomes, Human, X; | 2010 |
Segregation pattern and biochemical effect of the G3460A mtDNA mutation in 27 members of LHON family.
Topics: Alanine; Analysis of Variance; DNA Mutational Analysis; DNA, Mitochondrial; Family Health; Female; G | 2004 |