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nitrites and Optic Atrophy, Hereditary, Leber

nitrites has been researched along with Optic Atrophy, Hereditary, Leber in 1 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Optic Atrophy, Hereditary, Leber: A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))

Research Excerpts

ExcerptRelevanceReference
"Here we have collected evidence suggesting that chronic changes in the NO homeostasis and the rise of reactive oxygen species bioavailability can contribute to cell dysfunction in Leber's hereditary optic neuropathy (LHON) patients."1.43Evidence for Detrimental Cross Interactions between Reactive Oxygen and Nitrogen Species in Leber's Hereditary Optic Neuropathy Cells. ( Arese, M; Buscarinu, MC; Chessa, L; Coarelli, G; Falabella, M; Forte, E; Giuffrè, A; Magnifico, MC; Mechelli, R; Radić, K; Salvetti, M; Santini, P; Sarti, P, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Falabella, M1
Forte, E1
Magnifico, MC1
Santini, P1
Arese, M1
Giuffrè, A1
Radić, K1
Chessa, L1
Coarelli, G1
Buscarinu, MC1
Mechelli, R1
Salvetti, M1
Sarti, P1

Other Studies

1 other study available for nitrites and Optic Atrophy, Hereditary, Leber

ArticleYear
Evidence for Detrimental Cross Interactions between Reactive Oxygen and Nitrogen Species in Leber's Hereditary Optic Neuropathy Cells.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Adenosine Triphosphate; Adult; Cell Survival; Female; Flow Cytometry; Fluorometry; Humans; Leukocyte

2016