topiramate and Optic-Atrophy--Hereditary--Leber

topiramate has been researched along with Optic-Atrophy--Hereditary--Leber* in 1 studies

Other Studies

1 other study(ies) available for topiramate and Optic-Atrophy--Hereditary--Leber

Article	Year
Topiramate and visual loss in a patient carrying a Leber hereditary optic neuropathy mutation. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:2 We describe a 43-year-old patient who experienced visual loss 4 years after beginning antiepileptic therapy with topiramate. Ophthalmological and neurological examinations led to a preliminary diagnosis of bilateral toxic optic neuritis. Mitochondrial genome sequence analysis detected a Leber hereditary optic neuropathy 11778G>A mutation. The possibility that topiramate might favor a conversion disease, alerts physicians to seek a history of blindness in patients undergoing chronic antiepileptic therapy. Topics: Adult; Anticonvulsants; Blindness; Epilepsy; Fructose; Humans; Male; Mutation; Optic Atrophy, Hereditary, Leber; Topiramate; Visual Fields	2012

Article

Year

Topiramate and visual loss in a patient carrying a Leber hereditary optic neuropathy mutation.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:2

We describe a 43-year-old patient who experienced visual loss 4 years after beginning antiepileptic therapy with topiramate. Ophthalmological and neurological examinations led to a preliminary diagnosis of bilateral toxic optic neuritis. Mitochondrial genome sequence analysis detected a Leber hereditary optic neuropathy 11778G>A mutation. The possibility that topiramate might favor a conversion disease, alerts physicians to seek a history of blindness in patients undergoing chronic antiepileptic therapy.

Topics: Adult; Anticonvulsants; Blindness; Epilepsy; Fructose; Humans; Male; Mutation; Optic Atrophy, Hereditary, Leber; Topiramate; Visual Fields

2012