Page last updated: 2024-10-19

niacin and Hyperlipoproteinemia Type IV

niacin has been researched along with Hyperlipoproteinemia Type IV in 7 studies

Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.

Hyperlipoproteinemia Type IV: A hypertriglyceridemia disorder, often with autosomal dominant inheritance. It is characterized by the persistent elevations of plasma TRIGLYCERIDES, endogenously synthesized and contained predominantly in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). In contrast, the plasma CHOLESTEROL and PHOSPHOLIPIDS usually remain within normal limits.

Research Excerpts

ExcerptRelevanceReference
"Acipimox was about equally potent in reducing serum and VLDL lipid levels and in increasing HDL cholesterol levels."2.67A comparison between nicotinic acid and acipimox in hypertriglyceridaemia--effects on serum lipids, lipoproteins, glucose tolerance and tolerability. ( Tornvall, P; Walldius, G, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Havel, RJ1
Kane, JP1
Tornvall, P1
Walldius, G1
Gotto, AM1
Jones, PH1
Scott, LW1
Schaefer, EJ1
Levy, RI1
Parker, F1
Kushwaha, RS1
Haffner, SM1
Foster, DM1
Hazzard, WR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940]Phase 3120 participants (Actual)Interventional2018-05-28Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for niacin and Hyperlipoproteinemia Type IV

ArticleYear
Recommendations for treatment of hyperlipidemia in adults. A joint statement of the Nutrition Committee and the Council on Arteriosclerosis.
    Circulation, 1984, Volume: 69, Issue:5

    Topics: Cholesterol; Clofibrate; Coronary Disease; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperl

1984
Therapy of hyperlipidemic states.
    Annual review of medicine, 1982, Volume: 33

    Topics: Cholesterol, Dietary; Cholestyramine Resin; Clofibrate; Colestipol; Dietary Fats; Drug Therapy, Comb

1982
The diagnosis and management of hyperlipidemia.
    Disease-a-month : DM, 1986, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Cholesterol; Cholestyramine Resin; Chylomicrons; Clofibr

1986
Pathogenesis and management of lipoprotein disorders.
    The New England journal of medicine, 1985, May-16, Volume: 312, Issue:20

    Topics: Abetalipoproteinemia; Adolescent; Adult; Aged; Child; Child, Preschool; Cholestyramine Resin; Chylom

1985

Trials

1 trial available for niacin and Hyperlipoproteinemia Type IV

ArticleYear
A comparison between nicotinic acid and acipimox in hypertriglyceridaemia--effects on serum lipids, lipoproteins, glucose tolerance and tolerability.
    Journal of internal medicine, 1991, Volume: 230, Issue:5

    Topics: Adult; Blood Glucose; Female; Glucose Tolerance Test; Humans; Hyperlipoproteinemia Type II; Hyperlip

1991

Other Studies

2 other studies available for niacin and Hyperlipoproteinemia Type IV

ArticleYear
Xanthomas and hyperlipidemias.
    Journal of the American Academy of Dermatology, 1985, Volume: 13, Issue:1

    Topics: Apoproteins; Arteriosclerosis; Cholestasis; Cholestyramine Resin; Clofibrate; Colestipol; Dextrothyr

1985
Compositional and metabolic heterogeneity of alpha 2- and beta-very-low-density lipoproteins in subjects with broad beta disease and endogenous hypertriglyceridemia.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:11

    Topics: Adult; Aged; Cholesterol; Electrophoresis; Female; Humans; Hyperlipoproteinemia Type III; Hyperlipop

1985