gamma-aminobutyric acid has been researched along with Hallux Valgus in 1 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Hallux Valgus: Lateral displacement of the great toe (HALLUX), producing deformity of the first METATARSOPHALANGEAL JOINT with callous, bursa, or BUNION formation over the bony prominence.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Gargano, C | 1 |
| Lukac, S | 1 |
| Jackson, A | 1 |
| Beals, C | 1 |
| Smiley, P | 1 |
| Drexel, M | 1 |
| Ruddy, M | 1 |
| Herman, G | 1 |
| Johnson-Levonas, AO | 1 |
| Medve, R | 1 |
| Webster, L | 1 |
| Reicin, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Effect of Pregabalin and Naproxen Sodium on Postoperative Pain After Bunionectomy[NCT00601458] | Phase 1 | 100 participants (Actual) | Interventional | 2007-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Time (in hours) to first patient controlled analgesic (PCA) pump use after surgery in each of the treatment arms: placebo, pregabalin 300 mg or naproxen 550 mg. (NCT00601458)
Timeframe: First 24 hours following surgery
| Intervention | Hours (Median) |
|---|---|
| Pregabalin 300 mg | 7.3 |
| Naproxen Sodium 550 mg | 9.1 |
| Placebo | 5.8 |
Total dose (amount) of hydromorphone via patient controlled analgesic (PCA) pump required in the 24 hours post-surgery in each of the treatment arms: placebo, pregabalin 300 mg or naproxen 550 mg. (NCT00601458)
Timeframe: First 24 hours following surgery
| Intervention | milligrams (Geometric Mean) |
|---|---|
| Pregabalin 300 mg | 2.94 |
| Naproxen Sodium 550 mg | 2.07 |
| Placebo | 5.96 |
1 trial available for gamma-aminobutyric acid and Hallux Valgus
| Article | Year |
|---|---|
An enhanced bunionectomy model as a potential tool for early decision-making in the development of new analgesics.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Doubl | 2010 |