posaconazole has been researched along with Zygomycosis* in 2 studies
2 other study(ies) available for posaconazole and Zygomycosis
| Article | Year |
|---|---|
Posaconazole mono- or combination therapy for treatment of murine zygomycosis.
We compared the efficacy of combination posaconazole-liposomal amphotericin B (LAmB) therapy to monotherapy with either drug in diabetic ketoacidotic or neutropenic mice with disseminated zygomycosis caused by Rhizopus oryzae. Combination therapy was no better than LAmB alone, and posaconazole monotherapy did not improve survival or reduce fungal burden versus placebo. Topics: Amphotericin B; Animals; Antifungal Agents; Brain; Diabetic Ketoacidosis; Dose-Response Relationship, Drug; Drug Combinations; Kidney; Liposomes; Male; Mice; Mice, Inbred BALB C; Neutropenia; Rhizopus; Triazoles; Zygomycosis | 2009 |
In vitro activities of amphotericin B, caspofungin, itraconazole, posaconazole, and voriconazole against 45 clinical isolates of zygomycetes: comparison of CLSI M38-A, Sensititre YeastOne, and the Etest.
We evaluated the activities of amphotericin B, itraconazole, voriconazole, caspofungin, and posaconazole against zygomycetes by CLSI M38-A, Etest and Sensititre. The most active drug was posaconazole, followed by amphotericin B and itraconazole. The correlation of the Etest and Sensititre with CLSI M38-A was moderate for posaconazole but poor for the others. Topics: Antifungal Agents; Fungi; Humans; Microbial Sensitivity Tests; Quality Control; Zygomycosis | 2007 |