phenylephrine-hydrochloride and Zygomycosis

Conidiobolomycosis is an uncommon, chronic, localized subcutaneous mycosis primarily affecting rhinofacial region. It is reported mainly from tropical and subtropical countries. The condition is underreported due to the lack of clinical suspicion and usually mismanaged. This rare mycosis is due to the genus

Topics: Adolescent; Adult; Aged; Antifungal Agents; Conidiobolus; Dermatomycoses; Facial Dermatoses; Humans; Male; Nose; Zygomycosis

Subcutaneous zygomycosis is a chronic infection caused by fungus of the order Entomophthorales. It can have varying presentations and presents in the nose and face area with gradually progressing subcutaneous swelling that may be difficult to diagnose unless a strong suspicion of fungal involvement is maintained. We present a case of subcutaneous zygomycosis in a 35-year-old male patient, resident of a North Indian state. The patient was diagnosed to be suffering from subcutaneous zygomycosis, the causative agent being Basidiobolus ranarum identified on culture and lactophenol cotton blue mount preparation. He responded well to treatment with Itraconazole and Terbinafine and is asymptomatic on follow-up.. Involvement of the nose and subcutaneous tissues of the face in Basidiobolomycosis is rare. The infection is more common in children, but the case presented here is an adult. Its occurrence in a native of North India is also uncommon. Previous studies have mostly reported good response to potassium iodide therapy. Our patient responded well to Itraconazole. The presentation can be a diagnostic dilemma if fungal smear and culture is not sought, so this rare entity should be kept in mind in cases of indolent infections of the nose and facial soft tissues.

Topics: Adolescent; Adult; Antifungal Agents; Child; Child, Preschool; Dermatomycoses; Entomophthorales; Face; Female; Head; Humans; India; Infant; Itraconazole; Male; Middle Aged; Naphthalenes; Nose; Terbinafine; Tomography, X-Ray Computed; Treatment Outcome; Zygomycosis

Topics: Humans; Mucormycosis; Nose; Zygomycosis

Topics: Antifungal Agents; Humans; Nose; Zygomycosis

Conidiobolomycoses (Conidiobolus coronatus fungal infections) are rare and potentially severe infections prevalent in the tropics. The disease starts in the facial sinus and evolves as a subcutaneous tumor on the mid face. A 19-year-old female patient from Burkina Faso presented with an acquired nasal deformation having evolved for a few months, associated to bilateral nasal obstruction. The patient had no medical or surgical history. The pathological analysis of the surgical exeresis allowed diagnosing a C. coronatus infection.. The C. coronatus lives in decaying vegetation in hot and humid climates. It is a potential human pathogen that infects immunocompetent patients presenting with micro-wounds of the sinus and nasal mucosa. Hundred cases have been reported. The management is specific. The diagnosis should be discussed in case of distorting tumors of the midface.

Topics: Burkina Faso; Conidiobolus; Diagnosis, Differential; Face; Facial Asymmetry; Facial Neoplasms; Female; Humans; Nasal Obstruction; Nose; Young Adult; Zygomycosis

We describe a case of rhinoentomophthoromycosis, also known as rhinophycomycosis, in an Indian man hailing from the tropical northern region of the country. The patient presented with subcutaneous swelling in the midline of the forehead, dorsum of the nose, adjoining cheek area (more on the right side), philtrum, and upper lip. Biopsy taken from the right nostril area revealed nasofacial phycomycosis. The patient was treated successfully with itraconazole, 200 mg twice daily, and potassium iodide, 5 drops in fruit juice three times daily.

Topics: Antifungal Agents; Conidiobolus; Dermatomycoses; Humans; Itraconazole; Male; Middle Aged; Nose; Potassium Iodide; Tropical Medicine; Zygomycosis

Zygomycosis is an opportunistic fungal infection with a fulminant course. Varying clinical forms have been described, including cutaneous zygomycosis, which is mainly observed in diabetic and burns patients. We report herein a case of cutaneous zygomycosis of the nose in a 26-year-old female patient with diabetic ketoacidosis, developing secondary to the application of non-elasticized adhesive tape probably contaminated with fungal spores.

Topics: Adult; Amphotericin B; Antifungal Agents; Bandages; Cross Infection; Debridement; Dermatomycoses; Diabetic Ketoacidosis; Female; Humans; Mucormycosis; Nose; Rhizopus; Treatment Outcome; Zygomycosis

Rhinofacial Conidiobolus coronatus infection is a rare form of zygomycosis in humans living in the northern hemispheres. Most human cases are observed in the periequatorial areas of Africa, Asia, or South America. Only limited information regarding optimal treatment is available. We report a case of rhinofacial C. coronatus infection in an emigrated Sudanese patient. The infection was successfully treated with terbinafin and itraconazole for 12 months. Diagnosis was confirmed by microbiological culture from a tissue biopsy. Antimicrobial susceptibility testing of this organism was not predictive of optimal therapy.

Topics: Adult; Antifungal Agents; Conidiobolus; Emigrants and Immigrants; Face; Humans; Itraconazole; Magnetic Resonance Imaging; Male; Naphthalenes; Nose; Nose Deformities, Acquired; Sudan; Terbinafine; Young Adult; Zygomycosis

Topics: Adult; Antifungal Agents; Face; Humans; Male; Nose; Potassium Iodide; Zygomycosis

Topics: Animals; Brain; Nose; Sheep; Sheep Diseases; Zygomycosis

Topics: Black People; Diagnosis; Fungi; Humans; Mycoses; Nigeria; Nose; Nose Diseases; Pathology; Respiratory Tract Infections; Zygomycosis