Abetalipoproteinemia

An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features include defective intestinal lipid absorption, very low serum cholesterol level, and near absent LDL.

Synonym
Betalipoprotein Deficiency Disease
Microsomal Triglyceride Transfer Protein Deficiency Disease
Microsomal Triglyceride Transfer Protein Deficiency
Acanthocytosis
Bassen-Kornzweig Disease
Bassen-Kornzweig Syndrome
Abetalipoproteinemia

Excerpt	Reference
"Abetalipoproteinemia is characterized by the absence of chylomicrons, very low density and low density lipoproteins from the plasma."	( Dullaart, RP; Erkelens, DW, 1988)
"Abetalipoproteinemia is an inherited disorder of lipoprotein metabolism."	( Bayliss, JD; Bhattacharya, S; Brett, DJ; Cullen, PM; Grantham, TT; Jarmuz, A; Leoni, PR; Narcisi, TM; Pease, RJ; Shoulders, CC, 1993)
"Abetalipoproteinemia is a rare genetic disease that has provided important new insights into the physiology of lipoprotein assembly and vitamin E metabolism."	( Brewer, HB; Rader, DJ, 1993)
"Abetalipoproteinemia is a rare metabolic disorder that causes disturbed lipid absorption with consequent hypocholesterolaemia and liposoluble avitaminosis."	( Ferreira, F; Matts, S; Patel, V, 2014)
"Abetalipoproteinemia is a rare autosomal recessive disorder characterized by the inability to produce chylomicrons or very low-density lipoproteins, with the absence of apolipoprotein B-containing lipoproteins in the circulation."	( Burnett, JR; Hooper, AJ; Watts, GF, 2015)

Excerpt	Reference
"Patients with abetalipoproteinemia have an inborn absence of the major apoprotein of low density plasma lipoproteins, an abnormal serum and red cell lipid profile, and spiny erythrocytes, called acanthocytes."	( Lange, Y; Steck, TL, 1984)

Excerpt	Reference
"An 11-year-old girl with abetalipoproteinemia was treated with parenteral vitamin A and vitamin E for two and a half years."	( Azizi, E; Eshchar, J; Szeinberg, A; Zaidman, JL, 1978)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	169 (73.48)	23.3326
1990's	21 (9.13)	12.5806
2000's	21 (9.13)	18.1394
2010's	15 (6.52)	28.8240
2020's	4 (1.74)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
carbon monoxide	low	1	0
chlorine	low	2	0
niacin	low	1	0
nitrites	low	1	0
orotic acid	low	3	0
pyrazinamide	low	1	0
pyrogallol	low	2	0
1-anilino-8-naphthalenesulfonate	low	6	0
phenytoin	low	1	0
acetazolamide	low	1	0
aspirin	low	1	0
chlorpromazine	low	2	0
diazepam	low	1	0
furosemide	low	1	0
gemfibrozil	low	1	0
haloperidol	low	1	0
hydroxyzine	low	1	0
isoniazid	low	1	0
phenobarbital	low	1	0
probucol	low	1	0
trihexyphenidyl	low	1	0
prednisolone	low	1	0
aldosterone	low	1	0
etiocholanolone	low	1	0
alanine	low	1	0
aspartic acid	low	1	0
sucrose	low	1	0
ethinyl estradiol	low	1	0
adenosine diphosphate	low	2	0
galactose	low	2	0
edetic acid	low	1	0
tyrosine	low	1	0
leucine	low	1	0
methionine	low	1	0
cycloheximide	low	1	0
ornithine	low	1	0
tryptophan	low	1	0
n-vinyl-2-pyrrolidinone	low	1	0
framycetin	low	1	0
malondialdehyde	low	2	0
d-alpha tocopherol	medium	65	1
tocopherols	low	2	0
barium sulfate	low	1	0
deuterium	low	1	0
phytanic acid	low	3	0
phenyl acetate	low	1	0
alkenes	low	1	0
sodium azide	low	1	0
pravastatin	medium	1	1
atorvastatin	low	2	0
sudan black b	low	1	0
fat red 7b	low	1	0
colestipol	low	1	0
tocophersolan	low	1	0
fibrinogen	low	1	0
gamma-tocopherol	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
hydroxyl radical	low	1	0
o(4)-methylthymidine triphosphate	low	1	0
erythritol	low	1	0
cortisone	low	1	0
lanosterol	low	1	0
glycogen	low	1	0
fibrin	low	1	0
mevalonic acid	low	4	0
puromycin	low	1	0
indican	low	1	0
arachidonic acid	low	2	0
retinol	medium	23	1
sodium dodecyl sulfate	low	1	0
17-ketosteroids	low	1	0
bilirubin	low	1	0
linoleic acid	low	4	0
vitamin k semiquinone radical	low	1	0
beta carotene	low	1	0
leukotriene b4	low	1	0
thromboxane b2	low	1	0
brefeldin a	low	1	0
morphine	low	1	0
lysophosphatidylcholines	low	5	0
dimyristoylphosphatidylcholine	low	1	0
phosphorus	low	1	0
selenium	low	1	0
oxalates	low	1	0
dolichols	low	1	0
bms201038	low	1	0
acid phosphatase	low	1	0
oligonucleotides	low	1	0
phosphatidylcholines	low	11	0
glycolipids	low	9	0
piperidines	low	3	0
alectinib	low	2	0
ascorbic acid	low	1	0
vitamin b 12	low	6	0
thromboplastin	low	1	0
folic acid	low	2	0
cholestyramine resin	low	3	0

Protein Targets (1,304)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	2	0	0	2
thioredoxin reductase	12	0	0	12
USP1 protein, partial	16	0	0	16
TDP1 protein	19	0	0	19
vitamin D3 receptor isoform VDRA	10	0	0	10
importin subunit beta-1 isoform 1	5	0	0	5
flap endonuclease 1	4	0	0	4
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	5	0	0	5
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
DNA polymerase eta isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	6	0	0	6
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
geminin	22	0	0	22
DNA polymerase kappa isoform 1	9	0	0	9
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	0	2	2
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	4	2	6
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	1	1	2
Cyclin-dependent kinase 2	0	1	2	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	3	0	0	3
Fatty acid-binding protein 5	0	2	1	3
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	1	1	2
Mitogen-activated protein kinase 14	0	1	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	14	0	0	14
Chain A, Cruzipain	6	0	0	6
regulator of G-protein signaling 4	6	0	0	6
Platelet-activating factor receptor	0	2	0	2
Inositol monophosphatase 1	4	0	0	4
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	6	0	0	6
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	2	0	2
GALC protein	1	0	0	1
GLI family zinc finger 3	22	0	0	22
nuclear receptor subfamily 1, group I, member 3	14	0	0	14
cytochrome P450 family 3 subfamily A polypeptide 4	17	0	0	17
glucocorticoid receptor [Homo sapiens]	22	0	0	22
retinoic acid nuclear receptor alpha variant 1	25	0	0	25
retinoid X nuclear receptor alpha	16	0	0	16
estrogen-related nuclear receptor alpha	26	0	0	26
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	6	0	0	6
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	17	0	0	17
Bloom syndrome protein isoform 1	6	0	0	6
thyroid hormone receptor beta isoform a	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	18	0	0	18
peripheral myelin protein 22	8	0	0	8
survival motor neuron protein isoform d	5	0	0	5
muscleblind-like protein 1 isoform 1	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	9	4	1	14
ATP-binding cassette sub-family C member 3	0	11	0	11
Multidrug resistance-associated protein 4	0	11	0	12
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	4	0	4
Carbonic anhydrase 12	0	3	1	9
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	21	0	21
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	9	1	19
Carbonic anhydrase 2	0	10	2	20
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	2	1	3
Carbonic anhydrase 3	0	3	1	8
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	5	1	7
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	4	0	4
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2D6	0	3	1	4
Cytochrome P450 2A6	0	2	0	2
Cytochrome P450 2C9	0	8	1	9
5-hydroxytryptamine receptor 2A	0	4	0	4
Androgen receptor	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	9	4	1	14
Translocator protein	0	2	2	5
Gamma-aminobutyric acid receptor subunit delta	9	4	1	14
Gamma-aminobutyric acid receptor subunit gamma-2	9	4	1	14
Gamma-aminobutyric acid receptor subunit alpha-5	9	4	1	14
Gamma-aminobutyric acid receptor subunit alpha-3	9	4	1	14
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	2	0	2
Carbonic anhydrase 4	0	7	1	12
Carbonic anhydrase 6	0	4	1	9
Gamma-aminobutyric acid receptor subunit gamma-1	9	4	1	14
Gamma-aminobutyric acid receptor subunit alpha-2	9	4	1	14
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	4	0	5
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	9	4	1	14
Gamma-aminobutyric acid receptor subunit gamma-3	9	4	1	14
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	9	4	1	14
Adenosine receptor A2a	0	2	0	3
5-hydroxytryptamine receptor 2B	0	4	0	4
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	3	0	4
Cytochrome P450 2C19	0	2	0	2
Delta-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	5	1	9
Carbonic anhydrase 5A, mitochondrial	0	4	1	10
Carbonic anhydrase	0	4	0	6
Kappa-type opioid receptor	0	4	0	4
Carbonic anhydrase 7	0	3	1	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	2	2	0	4
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	1	0	3
D(2) dopamine receptor	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	9	5	1	15
Gamma-aminobutyric acid receptor subunit beta-3	9	4	1	14
Gamma-aminobutyric acid receptor subunit beta-2	9	4	1	14
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	4	0	6
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase 9	0	5	2	12
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	3
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	4
GABA theta subunit	9	4	1	14
Canalicular multispecific organic anion transporter 1	0	9	0	9
Carbonic anhydrase 4	0	2	0	4
Carbonic anhydrase 15	0	3	0	6
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	3	0	6
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	9	4	1	14
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	3	1	9
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	3	1	9
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	20	0	0	20
AR protein	27	0	0	27
pregnane X nuclear receptor	17	0	0	17
estrogen nuclear receptor alpha	30	0	0	30
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
heat shock protein beta-1	8	0	0	8
tumor susceptibility gene 101 protein	1	0	0	1
lamin isoform A-delta10	15	0	0	15
Voltage-dependent calcium channel gamma-2 subunit	9	0	0	9
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	2	1	4
Glutamate receptor 2	9	0	0	9
Xanthine dehydrogenase/oxidase	0	2	0	2
TAR DNA-binding protein 43	6	0	0	6
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	6	0	0	6
Ataxin-2	8	0	0	8
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	8	3	12
Delta-type opioid receptor	0	4	2	7
Kappa-type opioid receptor	0	6	2	9
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	4	0	6
Proton-coupled amino acid transporter 1	0	2	0	3
Adenosine deaminase	0	0	0	1
Sex hormone-binding globulin	0	0	4	4
Corticosteroid-binding globulin	0	4	0	4
Mineralocorticoid receptor	0	3	3	6
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	2
EWS/FLI fusion protein	9	0	0	9
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	1	1	2
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
Epidermal growth factor receptor	0	3	1	4
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Lck	0	0	1	1
Tyrosine-protein kinase Fyn	0	2	1	3
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	1	1	2
Tyrosine-protein kinase HCK	0	0	1	1
Proto-oncogene tyrosine-protein kinase ROS	0	1	0	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Spike glycoprotein	10	1	3	14
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Potassium voltage-gated channel subfamily H member 2	0	8	0	8
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Serine/threonine-protein kinase ATR	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Cyclin-dependent kinase 10	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
SRSF protein kinase 1	0	1	0	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Echinoderm microtubule-associated protein-like 4	0	1	0	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
ALK tyrosine kinase receptor	0	1	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
Chain A, 2-oxoglutarate Oxygenase	6	0	0	6
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
15-lipoxygenase, partial	5	0	0	5
phosphopantetheinyl transferase	10	0	0	10
Microtubule-associated protein tau	9	0	0	9
thioredoxin glutathione reductase	6	0	0	6
aldehyde dehydrogenase 1 family, member A1	17	0	0	17
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
nuclear receptor ROR-gamma isoform 1	7	0	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
cytochrome P450 3A4 isoform 1	9	0	0	9
histone acetyltransferase KAT2A isoform 1	9	0	0	9
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Prostaglandin G/H synthase 1	0	2	0	3
Trypsin	0	2	0	2
Coagulation factor VII	0	2	0	2
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Aromatase	0	2	0	2
Tissue factor	0	2	0	2
Prostaglandin G/H synthase 2	0	6	1	8
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Histamine H2 receptor	6	0	0	7
10 kDa heat shock protein, mitochondrial	0	1	0	1
Calmodulin	0	1	1	3
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Prostaglandin G/H synthase 2	0	2	0	3
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	2
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	9	0	11
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	10	0	13
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	15	0	0	15
IDH1	7	0	0	7
chromobox protein homolog 1	10	0	0	10
thyroid hormone receptor beta isoform 2	16	0	0	16
lethal factor (plasmid)	7	0	0	7
Polyphenol oxidase 2	0	3	0	4
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	4	1	5
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Ferritin light chain	3	0	0	3
cytochrome P450 2C19 precursor	1	0	0	1
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	0	5
Glutamate receptor ionotropic, NMDA 2C	0	3	0	5
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	3	0	5
Glutamate receptor ionotropic, NMDA 3B	0	3	0	5
Glutamate receptor ionotropic, NMDA 3A	0	3	0	5
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	7	0	0	7
GLS protein	6	0	0	6
thyroid stimulating hormone receptor	11	0	0	11
hypothetical protein, conserved	1	0	0	1
cytochrome P450 2D6	6	0	0	6
glucocerebrosidase	3	0	0	3
peroxisome proliferator-activated receptor delta	10	0	0	10
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
muscarinic acetylcholine receptor M1	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Fatty acid-binding protein, liver	0	5	0	5
Integrin beta-3	1	1	0	2
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Integrin alpha-IIb	1	1	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Substance-P receptor	0	2	0	2
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	5	0	0	5
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	7	1	8
Sigma non-opioid intracellular receptor 1	0	2	1	3
SMAD family member 2	4	0	0	4
SMAD family member 3	4	0	0	4
caspase 7, apoptosis-related cysteine protease	5	0	0	5
estrogen receptor 2 (ER beta)	12	0	0	12
peroxisome proliferator activated receptor gamma	12	0	0	12
caspase-3	5	0	0	5
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
Solute carrier organic anion transporter family member 2B1	0	2	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Cellular tumor antigen p53	15	0	0	15
ATP-dependent translocase ABCB1	0	5	0	8
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Histone deacetylase 1	0	1	0	1
Histone deacetylase 2	0	1	0	1
Histone deacetylase 6	0	1	0	1
core protein, partial	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Caspase-7	1	0	0	1
G	9	0	0	9
Interferon beta	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
Microsomal triglyceride transfer protein large subunit	0	1	0	1
Inositol hexakisphosphate kinase 1	9	0	0	9
cytochrome P450 2C9, partial	9	0	0	9
PAX8	0	0	0	1
ATAD5 protein, partial	5	0	0	5
Smad3	5	0	0	5
67.9K protein	5	0	0	5
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
major prion protein preproprotein Prp precursor	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
ras-related protein Rab-9A	3	0	0	3
steroidogenic factor 1	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
Fumarate hydratase	4	0	0	4
NFKB1 protein, partial	2	0	0	2
Thrombopoietin	2	0	0	2
progesterone receptor	10	0	0	10
NADPH oxidase 1	0	1	0	1
farnesoid X nuclear receptor	8	0	0	8
polyprotein	4	0	0	4
Snq2p	0	0	0	1
Adenylate cyclase type 1	0	3	0	3
thyroid stimulating hormone receptor	7	0	0	7
v-jun sarcoma virus 17 oncogene homolog (avian)	12	0	0	12
Histone H2A.x	5	0	0	5
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
cytochrome P450 2D6 isoform 1	3	0	0	3
D(1A) dopamine receptor	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
histone deacetylase 9 isoform 3	2	0	0	2
mitogen-activated protein kinase 1	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
M-phase phosphoprotein 8	3	0	0	3
Proteasome subunit alpha type-7	0	0	0	1
Solute carrier family 22 member 1	0	3	0	3
Transmembrane protease serine 2	0	1	3	4
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Bile salt export pump	0	3	0	3
5-hydroxytryptamine receptor 4	0	4	0	4
Potassium channel subfamily K member 2	0	2	0	2
Albumin	0	1	2	4
Albumin	0	0	3	3
Major prion protein	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Procathepsin L	0	1	3	4
Aldo-keto reductase family 1 member B1	0	6	0	6
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M1	0	4	0	4
Muscarinic acetylcholine receptor M3	0	4	0	4
Muscarinic acetylcholine receptor M4	0	4	0	4
5-hydroxytryptamine receptor 1A	0	3	0	3
Muscarinic acetylcholine receptor M5	0	4	0	4
Muscarinic acetylcholine receptor M5	0	6	0	6
Alpha-2A adrenergic receptor	0	4	1	5
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Replicase polyprotein 1ab	0	1	3	4
Muscarinic acetylcholine receptor M2	0	4	0	4
Muscarinic acetylcholine receptor M1	0	6	0	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Angiotensin-converting enzyme	0	3	0	3
D(2) dopamine receptor	0	5	1	9
Alpha-1B adrenergic receptor	0	7	0	7
Sphingomyelin phosphodiesterase	0	1	0	1
Alpha-2C adrenergic receptor	0	4	0	4
D	0	4	0	4
D(3) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 1A	0	7	1	8
Alpha-2B adrenergic receptor	0	3	0	3
D(2) dopamine receptor	0	3	0	3
Muscarinic acetylcholine receptor M3	0	5	0	5
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	4	0	6
D(4) dopamine receptor	0	4	1	8
D(1B) dopamine receptor	0	3	0	5
Adenylate cyclase type 3	0	3	0	3
Alpha-2C adrenergic receptor	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	0	0	2
Alpha-2A adrenergic receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	5	0	5
Sodium-dependent noradrenaline transporter	0	6	0	6
Sodium-dependent dopamine transporter	0	3	0	3
Histamine H2 receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	4	0	4
D(1B) dopamine receptor	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
5-hydroxytryptamine receptor 2C	0	4	0	4
5-hydroxytryptamine receptor 1B	0	3	0	3
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	4	0	4
Histamine H1 receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	6	0	6
Melanocortin receptor 4	0	2	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Histamine H1 receptor	0	5	0	5
D(3) dopamine receptor	0	4	1	8
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	4
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	7	0	7
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
5-hydroxytryptamine receptor 6	0	3	0	3
5-hydroxytryptamine receptor 7	0	3	0	3
Cytochrome P450 2J2	0	5	0	5
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	1	2
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Sodium-dependent dopamine transporter	0	4	0	4
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
D	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	4	0	4
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	1	3	4
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	2	0	2
endonuclease IV	2	0	0	2
dopamine D1 receptor	2	0	0	2
pregnane X receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
peripheral myelin protein 22 isoform 1	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Glucocorticoid receptor	0	6	1	12
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	4	0	4
glp-1 receptor, partial	5	0	0	5
PPM1D protein	2	0	0	2
P53	1	0	0	1
RPL19A	0	0	1	1
aryl hydrocarbon receptor	8	0	0	8
activating transcription factor 6	8	0	0	8
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
COUP transcription factor 2 isoform a	0	1	0	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Alpha-synuclein	4	1	0	5
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Gamma-aminobutyric acid	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
Eyes absent homolog 2	0	1	0	1
Amyloid-beta precursor protein	0	3	0	3
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Luciferase	6	0	0	6
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Vpr	1	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Cytochrome P450 2B1	0	1	0	1
Estrogen receptor	0	4	1	5
Adenosine receptor A3	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Estrogen receptor beta	0	3	1	4
ATP-dependent phosphofructokinase	7	0	0	7
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	1	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Chain A, Dihydrofolate reductase	0	0	1	1
alpha-galactosidase	2	0	0	2
DNA polymerase beta	1	0	0	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	2	0	3
30S ribosomal protein S7	0	2	0	3
50S ribosomal protein L15	0	2	0	3
50S ribosomal protein L10	0	2	0	3
50S ribosomal protein L11	0	2	0	3
50S ribosomal protein L7/L12	0	2	0	3
50S ribosomal protein L19	0	2	0	3
50S ribosomal protein L1	0	2	0	3
50S ribosomal protein L20	0	2	0	3
50S ribosomal protein L27	0	2	0	3
50S ribosomal protein L28	0	2	0	3
50S ribosomal protein L29	0	2	0	3
50S ribosomal protein L31	0	2	0	3
50S ribosomal protein L31 type B	0	2	0	3
50S ribosomal protein L32	0	2	0	3
50S ribosomal protein L33	0	2	0	3
50S ribosomal protein L34	0	2	0	3
50S ribosomal protein L35	0	2	0	3
50S ribosomal protein L36	0	2	0	3
30S ribosomal protein S10	0	2	0	3
30S ribosomal protein S11	0	2	0	3
30S ribosomal protein S12	0	2	0	3
30S ribosomal protein S13	0	2	0	3
30S ribosomal protein S16	0	2	0	3
30S ribosomal protein S18	0	2	0	3
30S ribosomal protein S19	0	2	0	3
30S ribosomal protein S20	0	2	0	3
30S ribosomal protein S2	0	2	0	3
30S ribosomal protein S3	0	2	0	3
30S ribosomal protein S4	0	2	0	3
30S ribosomal protein S5	0	2	0	3
30S ribosomal protein S8	0	2	0	3
30S ribosomal protein S9	0	2	0	3
50S ribosomal protein L13	0	2	0	3
50S ribosomal protein L14	0	2	0	3
50S ribosomal protein L16	0	2	0	3
50S ribosomal protein L23	0	2	0	3
30S ribosomal protein S15	0	2	0	3
50S ribosomal protein L17	0	2	0	3
50S ribosomal protein L21	0	2	0	3
50S ribosomal protein L30	0	2	0	3
50S ribosomal protein L6	0	2	0	3
30S ribosomal protein S14	0	2	0	3
30S ribosomal protein S17	0	2	0	3
30S ribosomal protein S1	0	2	0	3
50S ribosomal protein L18	0	2	0	3
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	2	0	3
50S ribosomal protein L3	0	2	0	3
50S ribosomal protein L24	0	2	0	3
50S ribosomal protein L4	0	2	0	3
50S ribosomal protein L22	0	2	0	3
50S ribosomal protein L5	0	2	0	3
30S ribosomal protein S21	0	2	0	3
50S ribosomal protein L25	0	2	0	3
50S ribosomal protein L36 2	0	2	0	3
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
thyrotropin-releasing hormone receptor	2	0	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
cytochrome P450 2C9 precursor	3	0	0	3
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Cannabinoid receptor 2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
Peroxisome proliferator-activated receptor alpha	3	0	1	4
nonstructural protein 1	1	0	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	2
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
Beta-1 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
Histamine H1 receptor	0	2	0	2
C-8 sterol isomerase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
Kappa-type opioid receptor	0	3	1	5
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Histamine H4 receptor	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Alpha-crystallin B chain	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	0	1
14-alpha sterol demethylase	0	0	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	4	0	4
Phospholipase A-2-activating protein	0	2	0	2
Leukotriene B4 receptor 1	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Sterol O-acyltransferase 1	0	1	0	1
Fatty acid-binding protein, heart	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 7	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Dual specificity protein phosphatase 3	0	1	0	1
Free fatty acid receptor 4	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
transcriptional regulator ERG isoform 3	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 7	0	1	0	1
luciferase	0	0	0	1
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Vascular cell adhesion protein 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Puromycin-sensitive aminopeptidase	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Autoinducer 2-binding periplasmic protein LuxP	0	1	0	1
5-lipoxygenase	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Laccase	0	1	0	1
Integrase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
eyes absent homolog 2 isoform a	1	0	0	1
C-terminal-binding protein 1	1	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Dihydrofolate reductase	0	2	0	2
Plasma kallikrein	0	0	0	2
Stromelysin-1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	2
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (230)

Protein Targets (1,304)

Abetalipoproteinemia

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (230)

Drugs Studied (125)

Protein Targets (1,304)