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chlorpromazine and Abetalipoproteinemia

chlorpromazine has been researched along with Abetalipoproteinemia in 2 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Abetalipoproteinemia: An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features include defective intestinal lipid absorption, very low serum cholesterol level, and near absent LDL.

Research Excerpts

ExcerptRelevanceReference
"Patients with abetalipoproteinemia have an inborn absence of the major apoprotein of low density plasma lipoproteins, an abnormal serum and red cell lipid profile, and spiny erythrocytes, called acanthocytes."1.27Mechanism of red blood cell acanthocytosis and echinocytosis in vivo. ( Lange, Y; Steck, TL, 1984)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lange, Y2
Steck, TL1

Other Studies

2 other studies available for chlorpromazine and Abetalipoproteinemia

ArticleYear
The dynamics of erythrocyte membrane cholesterol.
    Progress in clinical and biological research, 1984, Volume: 159

    Topics: Abetalipoproteinemia; Biological Transport; Chlorpromazine; Cholesterol; Erythrocyte Membrane; Eryth

1984
Mechanism of red blood cell acanthocytosis and echinocytosis in vivo.
    The Journal of membrane biology, 1984, Volume: 77, Issue:2

    Topics: Abetalipoproteinemia; Acanthocytes; Chlorpromazine; Erythrocyte Membrane; Erythrocytes, Abnormal; Fe

1984