neomethymycin: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
neomethymycin : A twelve-membered macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 5282033 |
| CHEMBL ID | 521954 |
| CHEBI ID | 29656 |
| SCHEMBL ID | 652365 |
| MeSH ID | M0052577 |
| Synonym |
|---|
| 2bsx67j222 , |
| unii-2bsx67j222 |
| methymycin, 10-deoxy-12-hydroxy-, (12r)- |
| neomethymycin |
| 497-73-4 |
| LMPK04000036 |
| chebi:29656 , |
| CHEMBL521954 |
| (3r,4s,5s,7r,9e,11r,12s)-4-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-12-[(1r)-1-hydroxyethyl]-3,5,7,11-tetramethyl-1-oxacyclododec-9-ene-2,8-dione |
| SCHEMBL652365 |
| (3r,4s,5s,7r,9e,11r,12s)-12-[(1r)-1-hydroxyethyl]-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-d-xylo-hexopyranoside |
| (12r)-10-deoxy-12-hydroxymethymycin |
| oxacyclododec-9-ene-2,8-dione, 12-((1r)-1-hydroxyethyl)-3,5,7,11-tetramethyl-4-((3,4,6-trideoxy-3-(dimethylamino)-.beta.-d-xylo-hexopyranosyl)oxy)-, (3r,4s,5s,7r,9e,11r,12s)- |
| 3r,4s,5s,7r,9e,11r,12s)-12-((1r)-1-hydroxyethyl)-3,5,7,11-tetramethyl-4-((3,4,6-trideoxy-3-(dimethylamino)-.beta.-d-xylo-hexopyranosyl)oxy)oxacyclododec-9-ene-2,8-dione |
| neomethymycin [mi] |
| Q27110209 |
| DTXSID201026558 |
| AKOS040734840 |
| Role | Description |
|---|---|
| bacterial metabolite | Any prokaryotic metabolite produced during a metabolic reaction in bacteria. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| enone | An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position. |
| macrolide antibiotic | A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity. |
| monosaccharide derivative | A carbohydrate derivative that is formally obtained from a monosaccharide. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID358289 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 100 ug/disk after 10 hrs by disk diffusion assay | 2001 | Journal of natural products, Nov, Volume: 64, Issue:11 | Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||