Page last updated: 2024-09-27

Ganglion Cysts

Nodular tumor-like lesions or mucoid flesh, arising from tendon sheaths, LIGAMENTS, or JOINT CAPSULE, especially of the hands, wrists, or feet. They are not true cysts as they lack epithelial wall. They are distinguished from SYNOVIAL CYSTS by the lack of communication with a joint cavity or the SYNOVIAL MEMBRANE.

Synonyms(4)

Synonym
Ganglionic Cysts
Ganglions
Myxoid Cyst
Ganglion Cysts

Research Excerpts

Overview

ExcerptReference
"Ganglion cysts are the most common lesion of the hand and wrist, accounting for 50% to 70% of all masses identified."( Bucchieri, JS; Nahra, ME, 2004)
"Ganglion cysts are ubiquitous cystic lesions without synovial wall and inconstant communication with the articular cavity."( Aubry, S; Kastler, B; Laborie, L; Lerais, JM; Puget, J; Sarlieve, P, 2006)
"While extraneural ganglion cysts are common and well known, intraneural ganglia are rare and misunderstood."( Amrami, KK; Colbert, SH; Howe, BM; Spinner, RJ; Wang, H, 2012)
"Intraneural ganglion cysts are uncommon cystic lesions of peripheral nerves that are typically encountered in adults."( Emery, KH; Johnson, N; Sorger, J; Squires, JH, 2014)
"Ganglion cysts are considered the most common tumor of the wrist and hand."( Hass, A; Oron, A; Sarig, O, 2013)
"Ganglion cysts are common benign lesions in the hand and wrist."( Majima, T; Motoda, N; Nanno, M; Tomori, Y, 2021)
"Ganglion cysts are the most common soft tissue tumor of the hand and wrist, affecting pediatric and adult populations."( Al-Ani, S; Baldrighi, C; Jester, A; Oestreich, K; Ting, JWC; Zhou, J, 2022)
"Ganglion cysts are the most common mass of the hand or wrist."( Bram, JT; Chang, B; Falk, DP; Fazal, FZ; Lin, IC; Shah, AS; Ty, JM, 2021)
"Ganglion cysts are most commonly encountered at the dorsal or volar aspects of the wrist, although cysts may arise from the flexor tendon sheath, interphalangeal joint, and extensor tendons."( Benner, NR; Iannuzzi, NP; Zoller, SD, 2023)
"Ganglion cysts are benign lesions frequently seen in hand pathologies, but they are rarely seen in the foot and ankle."( Azam, MT; Kennedy, JG; Ubillus, HA; Walls, RC; Walls, RJ, 2023)

Context

ExcerptReference
"In adults, ganglions have a female predilection and are commonly located in the dorsal wrist."( Bram, JT; Chang, B; Falk, DP; Fazal, FZ; Lin, IC; Shah, AS; Ty, JM, 2021)

Treatment

ExcerptReference
"The majority of ganglion cysts can be treated nonoperatively but when surgery is performed a low recurrence rate can be anticipated."( Bucchieri, JS; Nahra, ME, 2004)
"Trigger digit, Dupuytren's disease, and ganglion cysts are 3 common disorders treated by hand surgeons."( Avery, EC; McCabe, SJ, 2023)

Research

Studies (164)

TimeframeStudies, This Condition (%)All Conditions %
pre-199019 (11.59)23.3326
1990's0 (0.00)12.5806
2000's51 (31.10)18.1394
2010's75 (45.73)28.8240
2020's19 (11.59)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
ammonium hydroxide0low10
chlorine0low10
histamine0low30
acetaminophen0medium21
bupivacaine0low10
caffeine0low10
celecoxib0low10
amphetamine0low10
gentamicin0low10
guaifenesin0low30
hexamethonium0low10
ibuprofen0medium11
lidocaine0low10
indomethacin0low10
iohexol0low10
apnea0low10
octopamine0low20
procaine0low20
propranolol0low10
tranexamic acid0low10
carbachol0low10
estrone0low10
methylprednisolone acetate0medium21
pilocarpine0low30
physostigmine0low10
phenylephrine0medium21
tyrosine0low10
methylene blue0low30
triamcinolone acetonide0medium31
caramiphen0low10
methylprednisolone0medium21
cyclopentane0low10
perfluorobutane0low10
betamethasone0low10
glycopyrrolate0medium11
trimecaine0low10
fluorescein0low10
n-methylaspartate0low10
trimethaphan0medium11
gadolinium0low30
barium chloride0low10
trolamine salicylate0low40
osmium tetroxide0low10
cetylpyridinium chloride anhydrous0medium11
glutamic acid0low10
substance p0low10
adenosine0low10
plerixafor0low10
betamethasone sodium phosphate0low10
epibatidine0low10
methotrexate0low10
atropine0low10
fibrin0low10
y 276320low10
enkephalin, leucine0low10
picibanil0low20
polidocanol0low20
indigo carmine0low10
cystine0low10
allatostatin 10low10
glyceryl 2-arachidonate0low10
hydrocodone0medium21
morphine0low20
dexmedetomidine0medium11
barium0low10
silicon0low10
gadolinium dtpa0low40
orcokinin0low20
glucagon-like peptide 10low10
incretins0low10
sodium tetradecyl sulfate0low20
vasoactive intestinal peptide0low10
ascorbic acid0low10
minocycline0low10
allatotropin0low10
peptide yy0low10
chondroitin sulfates0low10
cyclic gmp0low10
eye0low20

Protein Targets (943)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma160016
ATAD5 protein, partial100010
GLS protein120012
Microtubule-associated protein tau9009
Smad34004
aldehyde dehydrogenase 1 family, member A16006
thyroid stimulating hormone receptor9009
nuclear receptor subfamily 1, group I, member 3110011
progesterone receptor140014
EWS/FLI fusion protein110011
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha180018
estrogen-related nuclear receptor alpha210021
estrogen nuclear receptor alpha300030
peroxisome proliferator activated receptor gamma130013
aryl hydrocarbon receptor110011
chromobox protein homolog 1110011
thyroid hormone receptor beta isoform 2150015
peripheral myelin protein 22100010
cytochrome P450 3A4 isoform 17007
Gamma-aminobutyric acid receptor subunit pi73111
ATP-binding cassette sub-family C member 3013013
Multidrug resistance-associated protein 4013015
Solute carrier family 22 member 60303
Carbonic anhydrase 120204
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0505
Voltage-dependent calcium channel gamma-2 subunit120012
Bile salt export pump020020
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10508
Carbonic anhydrase 205110
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20102
Prostaglandin G/H synthase 10607
Carbonic anhydrase 30204
Cytochrome P450 3A40314
Cytochrome P450 2D60404
Cytochrome P450 2C9 0707
Polyunsaturated fatty acid lipoxygenase ALOX150202
Gamma-aminobutyric acid receptor subunit beta-173111
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta73111
Gamma-aminobutyric acid receptor subunit gamma-273212
UDP-glucuronosyltransferase 1-60001
Glutamate receptor 2123116
Gamma-aminobutyric acid receptor subunit alpha-573111
Gamma-aminobutyric acid receptor subunit alpha-373111
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0001
Carbonic anhydrase 40305
Prostaglandin G/H synthase 10405
Carbonic anhydrase 60204
Gamma-aminobutyric acid receptor subunit gamma-173111
Gamma-aminobutyric acid receptor subunit alpha-273111
Gamma-aminobutyric acid receptor subunit alpha-473111
Gamma-aminobutyric acid receptor subunit gamma-373111
Gamma-aminobutyric acid receptor subunit alpha-673111
Carbonic anhydrase 5A, mitochondrial0204
Prostaglandin G/H synthase 20529
Carbonic anhydrase 70204
Nuclear receptor ROR-gamma3003
Cytochrome P450 2J20505
Gamma-aminobutyric acid receptor subunit alpha-174213
Gamma-aminobutyric acid receptor subunit beta-373111
Gamma-aminobutyric acid receptor subunit beta-273212
Carbonic anhydrase 90305
GABA theta subunit73111
Canalicular multispecific organic anion transporter 1013013
Carbonic anhydrase 150305
Carbonic anhydrase 130102
Gamma-aminobutyric acid receptor subunit epsilon73111
Carbonic anhydrase 140204
Carbonic anhydrase 5B, mitochondrial0204
toxin B0001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE120012
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein270027
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 48008
glucocorticoid receptor [Homo sapiens]230023
NPYLR7B0011
arylsulfatase A110011
IDH1130013
Histone H2A.x6006
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 14004
flap endonuclease 15005
nuclear receptor ROR-gamma isoform 16006
survival motor neuron protein isoform d5005
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Rap guanine nucleotide exchange factor 33003
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0303
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A306310
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A106110
Adenosine receptor A30202
Adenosine receptor A2a04410
Adenosine receptor A2b0114
Adenosine receptor A2b0315
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10339
Adenosine receptor A2a05110
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10112
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Solute carrier family 22 member 30101
5-hydroxytryptamine receptor 2C0214
Phenylethanolamine N-methyltransferase0202
Cytochrome P450 2A60213
Substance-P receptor0303
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 1A0427
Cytochrome P450 2A50101
Sodium-dependent dopamine transporter0303
5-hydroxytryptamine receptor 1B0314
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0112
5-hydroxytryptamine receptor 60011
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
Sigma non-opioid intracellular receptor 10112
5-hydroxytryptamine receptor 4 0011
Beta-2 adrenergic receptor0315
5-hydroxytryptamine receptor 3B0011
Sigma non-opioid intracellular receptor 10101
thioredoxin reductase130013
TDP1 protein180018
euchromatic histone-lysine N-methyltransferase 2230023
Bloom syndrome protein isoform 1100010
D(1A) dopamine receptor5005
lamin isoform A-delta10160016
neuropeptide S receptor isoform A4004
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase8008
GLI family zinc finger 3150015
thioredoxin glutathione reductase3003
cytochrome P450 family 3 subfamily A polypeptide 49009
vitamin D (1,25- dihydroxyvitamin D3) receptor130013
nuclear factor erythroid 2-related factor 2 isoform 2100010
nuclear factor erythroid 2-related factor 2 isoform 1140014
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin190019
lethal factor (plasmid)3003
Polyphenol oxidase 20102
Pancreatic alpha-amylase0202
Albumin0203
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0326
Spike glycoprotein9009
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, 2-oxoglutarate Oxygenase6006
pregnane X nuclear receptor130013
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta4004
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0405
5-hydroxytryptamine receptor 40404
Muscarinic acetylcholine receptor M208517
Muscarinic acetylcholine receptor M405311
Muscarinic acetylcholine receptor M108215
Muscarinic acetylcholine receptor M308214
Muscarinic acetylcholine receptor M408113
Muscarinic acetylcholine receptor M508113
Muscarinic acetylcholine receptor M506312
Muscarinic acetylcholine receptor M209115
Muscarinic acetylcholine receptor M107617
Muscarinic acetylcholine receptor M10124
Muscarinic acetylcholine receptor M307414
Alpha-1D adrenergic receptor0315
5-hydroxytryptamine receptor 2C0415
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor3015
5-hydroxytryptamine receptor 70303
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0315
pregnane X receptor2002
farnesoid X nuclear receptor120012
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a120012
nuclear receptor subfamily 1, group I, member 26006
thyroid hormone receptor beta isoform a8008
galanin receptor type 30101
Glucocorticoid receptor0808
Glycine receptor subunit alpha-10808
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
ORF730011
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20123
Potassium channel subfamily K member 90101
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
phosphopantetheinyl transferase9009
thyroid stimulating hormone receptor7007
v-jun sarcoma virus 17 oncogene homolog (avian)8008
atrial natriuretic peptide receptor 1 precursor4004
DNA polymerase kappa isoform 17007
muscarinic acetylcholine receptor M15005
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0404
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0101
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0304
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Guanine deaminase0101
ATP-dependent phosphofructokinase8008
D0101
D(2) dopamine receptor0213
Sigma non-opioid intracellular receptor 10404
Chain A, Beta-lactamase4004
GALC protein3003
thyrotropin-releasing hormone receptor4004
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40303
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20303
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Delta-type opioid receptor0519
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Muscarinic acetylcholine receptor M30013
Muscarinic acetylcholine receptor M20003
Neuronal acetylcholine receptor subunit alpha-100101
Chain A, Carbonic anhydrase II0101
Chain A, Cruzipain3003
Carbonic anhydrase 0001
Carbonic anhydrase 0101
GTP-binding protein (rab7)0011
ras protein, partial0011
glp-1 receptor, partial5005
hypoxia-inducible factor 1 alpha subunit100010
SMAD family member 29009
USP1 protein, partial7007
PPM1D protein3003
SMAD family member 39009
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)100010
G6006
cytochrome P450 2D67007
Carbonic anhydrase 0101
Carbonic anhydrase 0101
67.9K protein6006
peroxisome proliferator-activated receptor delta9009
Carbonic anhydrase0101
Rac1 protein0011
caspase-35005
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
activating transcription factor 65005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
Caspase-71001
interferon gamma precursor0001
prostaglandin E2 receptor EP2 subtype0001
potassium voltage-gated channel subfamily H member 2 isoform d3003
caspase-31001
heat shock protein beta-19009
Prostaglandin E synthase0202
Histone deacetylase 30202
3-phosphoinositide-dependent protein kinase 10101
Prostaglandin G/H synthase 1 0304
Prostaglandin G/H synthase 2 0304
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Cytochrome c oxidase subunit 10101
Cytochrome c oxidase subunit 20101
Catechol O-methyltransferase0101
Cytochrome c oxidase subunit 20202
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 6006
Cellular tumor antigen p53120012
Procathepsin L0202
Aldo-keto reductase family 1 member B10202
Seed linoleate 13S-lipoxygenase-10101
Polyunsaturated fatty acid 5-lipoxygenase0101
Quinolone resistance protein NorA0101
Beta-3 adrenergic receptor0426
Alpha-1B adrenergic receptor0718
Calpain-2 catalytic subunit0101
D(1A) dopamine receptor0314
Prostaglandin G/H synthase 10303
Sodium-dependent noradrenaline transporter 0213
Cruzipain0202
Sodium/hydrogen exchanger 10101
Indoleamine 2,3-dioxygenase 10202
Sodium-dependent serotonin transporter0606
Sodium-dependent serotonin transporter0112
Delta-type opioid receptor0517
Mu-type opioid receptor05210
Bifunctional epoxide hydrolase 20202
Prostaglandin G/H synthase 2 0304
Carbonic anhydrase0204
Alpha-1A adrenergic receptor0718
Urotensin-2 receptor0101
Carbonic anhydrase0104
Histone deacetylase 40202
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20606
Carbonic anhydrase 0101
Mu-type opioid receptor0718
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Sodium-dependent dopamine transporter 0202
Prostaglandin G/H synthase 20304
Histone deacetylase 10202
Mitogen-activated protein kinase 140101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0104
Carbonic anhydrase0104
Carbonic anhydrase0104
Carbonic anhydrase 0101
Sigma intracellular receptor 20202
Delta carbonic anhydrase0101
Prostaglandin G/H synthase 1 0304
Carbonic anhydrase 0104
Prostaglandin G/H synthase 10101
Carbonic anhydrase 130102
Cyclooxygenase-2 0101
Histone deacetylase 70202
Rap guanine nucleotide exchange factor 41001
Inositol hexakisphosphate kinase 16006
Histone deacetylase 20202
Carbonic anhydrase 40203
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
ATPase family AAA domain-containing protein 59009
Ataxin-2100010
Histone deacetylase 80202
P2Y purinoceptor 120202
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
cytochrome P450 2C9, partial6006
Chain A, Ferritin light chain5005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
vitamin D3 receptor isoform VDRA5005
Caspase-20011
Inositol monophosphatase 13003
Phosphodiesterase 0101
Multidrug resistance-associated protein 50001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Alpha-1B adrenergic receptor 0022
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a2002
cytochrome P450 2C19 precursor3003
cytochrome P450 2C9 precursor3003
Alpha-2A adrenergic receptor0359
Alpha-1A adrenergic receptor0123
Alpha-2C adrenergic receptor0348
Alpha-2B adrenergic receptor0213
Alpha-2C adrenergic receptor0213
Alpha-2A adrenergic receptor0213
Alpha-1D adrenergic receptor0516
Opioid receptor, delta 1b 0202
Opioid receptor homologue0202
Proenkephalin-B0011
Kappa-type opioid receptor0315
Kappa-type opioid receptor0416
Mu-type opioid receptor06310
Delta-type opioid receptor0438
Kappa-type opioid receptor0303
Kappa-type opioid receptor0539
Mu-type opioid receptor0316
Mu-type opioid receptor0202
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
endonuclease IV1001
NFKB1 protein, partial5005
nonstructural protein 14004
hexokinase-4 isoform 12002
peripheral myelin protein 22 isoform 13003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
glucokinase regulatory protein2002
DNA polymerase iota isoform a (long)7007
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
Estrogen receptor0214
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0101
Steryl-sulfatase0101
Aromatase0101
17-beta-hydroxysteroid dehydrogenase type 10203
Androgen receptor0404
Alpha-synuclein1102
5-hydroxytryptamine receptor 2B0415
Solute carrier organic anion transporter family member 1A10202
TAR DNA-binding protein 436006
Cytochrome P450 1B10101
Estrogen receptor beta0113
Ghrelin O-acyltransferase0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
histone acetyltransferase KAT2A isoform 17007
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B5005
transcriptional regulator ERG isoform 33003
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10202
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Sodium- and chloride-dependent betaine transporter0202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Gamma-aminobutyric acid receptor subunit alpha-60112
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0011
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Gamma-aminobutyric acid type B receptor subunit 10011
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid type B receptor subunit 10101
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0112
Glucagon receptor0011
Glucagon receptor0011
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0304
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Integrin beta-31012
Integrin alpha-IIb1012
ATP-citrate synthase 0101
Glutamate receptor 10314
Glutamate receptor 30314
Glutamate receptor 40314
Glutamate receptor ionotropic, kainate 10314
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50123
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0429
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20314
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30303
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, NMDA 2A 0429
Glutamate receptor ionotropic, NMDA 2B0429
Glutamate receptor ionotropic, NMDA 2C0429
Glutamate receptor ionotropic, kainate 40303
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, NMDA 2D0429
Glutamate receptor ionotropic, kainate 50303
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0429
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0429
alpha-galactosidase2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
Fatty-acid amide hydrolase 10101
Fatty acid-binding protein, liver0101
Cannabinoid receptor 10101
Cannabinoid receptor 10112
Cannabinoid receptor 2 0112
Cannabinoid receptor 20101
ras-related protein Rab-9A3003
M-phase phosphoprotein 85005
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
apical membrane antigen 1, AMA11001
transforming acidic coiled-coil-containing protein 30001
Solute carrier family 22 member 20001
Solute carrier family 22 member 30102
Plasma kallikrein0002
Macrophage migration inhibitory factor0202
Histamine H2 receptor0123
5-hydroxytryptamine receptor 1D0001
Histamine H1 receptor0123
Histamine H1 receptor0213
Histamine H1 receptor0224
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Solute carrier family 22 member 10102
Equilibrative nucleoside transporter 40001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Histamine H4 receptor0123
Histamine H3 receptor0101
Carboxylic ester hydrolase 0102
Solute carrier family 22 member 20102
Histamine H3 receptor0123
Mas-related G-protein coupled receptor member X20033
Luciferase6006
importin subunit beta-1 isoform 13003
snurportin-13003
muscleblind-like protein 1 isoform 15005
Acid-sensing ion channel 30101
Solute carrier organic anion transporter family member 1A40101
Dihydrofolate reductase0304
Fatty acid-binding protein, liver0101
Albumin0246
Albumin0011
Fatty acid-binding protein, intestinal0101
Polyunsaturated fatty acid 5-lipoxygenase0204
UDP-glucuronosyltransferase 2B70001
Caspase-10102
Substance-P receptor0303
UDP-glucuronosyltransferase 1A30002
Aldo-keto reductase family 1 member C30303
Caspase-30101
Caspase-40101
4-aminobutyrate aminotransferase, mitochondrial0101
Caspase-50101
Caspase-90101
Acid-sensing ion channel 10101
Solute carrier family 22 member 60203
Solute carrier family 22 member 200202
Solute carrier family 22 member 80203
Solute carrier family 22 member 60202
Dehydrogenase/reductase SDR family member 90101
histone deacetylase 9 isoform 32002
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
interleukin 81001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
glucocerebrosidase1001
Parkin1001
serine/threonine-protein kinase mTOR isoform 11001
Prostaglandin-H2 D-isomerase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Phospholipase A2, major isoenzyme0101
ATP-dependent translocase ABCB10404
Interleukin-80101
Androgen receptor0011
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Thromboxane-A synthase 0101
Serum paraoxonase/arylesterase 10101
Nitric oxide synthase, inducible0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0102
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G2002
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Potassium voltage-gated channel subfamily H member 20505
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0101
Multidrug and toxin extrusion protein 10202
Dehydrogenase/reductase SDR family member 90101
Solute carrier organic anion transporter family member 1B30203
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
dopamine D1 receptor4004
ClpP1001
15-lipoxygenase, partial1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
DNA polymerase eta isoform 12002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40303
Chain E, Fibrin beta chain0101
Chain A, JmjC domain-containing histone demethylation protein 3A2002
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
Fumarate hydratase3003
TSHR protein1001
Apoptotic peptidase activating factor 10101
hypothetical protein, conserved1001
isocitrate dehydrogenase 1, partial1001
polyprotein3003
luciferase1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
huntingtin isoform 22002
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
Vpr1001
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glycoprotein hormones alpha chain1001
Amyloid-beta precursor protein0101
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor subfamily 1 group I member 20011
GTP-binding nuclear protein Ran isoform 11001
Stromelysin-10101
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Indoleamine 2,3-dioxygenase 10101
Acetylcholinesterase0304
ATP-dependent translocase ABCB10101
Acyl-CoA desaturase 10101
Translocator protein0011
ATP-dependent translocase ABCB10101
Proteinase-activated receptor 10112
Nociceptin receptor0101
Mu-type opioid receptor0101
POU domain, class 2, transcription factor 10002
5-hydroxytryptamine receptor 3A0011
Trace amine-associated receptor 10011
Beta-2 adrenergic receptor0224
Beta-1 adrenergic receptor0224
Beta-1 adrenergic receptor0315
Alpha-1B adrenergic receptor0101
Alpha-2B adrenergic receptor0001
Alpha-1A adrenergic receptor0236
Alpha-1B adrenergic receptor0124
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Acetylcholinesterase0101
Acetylcholinesterase0101
Acetylcholinesterase 0101
Acetylcholinesterase0101
Acetylcholinesterase0101
Cholinesterase0203
Cholinesterase0101
Acyl-CoA:cholesterol acyltransferase 0101
Carboxylic ester hydrolase 0101
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
C-X-C chemokine receptor type 40101
Atypical chemokine receptor 30011
C-C chemokine receptor type 20101
C-X-C chemokine receptor type 40204
Beta-1 adrenergic receptor 0113
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 1A0101
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80101
D(2) dopamine receptor0112
D(3) dopamine receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2A0213
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
Cytochrome P450 2C190101
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Vasopressin V1a receptor0112
5-hydroxytryptamine receptor 60213
Beta-2 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium/bile acid cotransporter0101
Nuclear receptor subfamily 2 group E member 10022
Neuromedin-K receptor0011
Substance-K receptor0112
Substance-K receptor0202
Substance-P receptor0213
Neuromedin-K receptor0112
Substance-K receptor0101
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
procathepsin L isoform 1 preproprotein0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Tubulin--tyrosine ligase0101
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor, alpha form0101
Chain B, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, Rho-associated protein kinase 10101
Rho-associated protein kinase 20202
Ribosomal protein S6 kinase alpha-50101
cAMP-dependent protein kinase catalytic subunit alpha0101
cAMP-dependent protein kinase catalytic subunit alpha 0101
C-C motif chemokine 20101
cAMP-dependent protein kinase catalytic subunit alpha0101
cAMP-dependent protein kinase catalytic subunit gamma0101
cAMP-dependent protein kinase catalytic subunit beta0101
Rho-associated protein kinase 10202
Serine/threonine-protein kinase N20101
Rho-associated protein kinase 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]