Ganglion Cysts

Nodular tumor-like lesions or mucoid flesh, arising from tendon sheaths, LIGAMENTS, or JOINT CAPSULE, especially of the hands, wrists, or feet. They are not true cysts as they lack epithelial wall. They are distinguished from SYNOVIAL CYSTS by the lack of communication with a joint cavity or the SYNOVIAL MEMBRANE.

Synonyms(4)

Synonym
Ganglionic Cysts
Ganglions
Myxoid Cyst
Ganglion Cysts

Research Excerpts

Overview

Excerpt	Reference
"Ganglion cysts are the most common lesion of the hand and wrist, accounting for 50% to 70% of all masses identified."	( Bucchieri, JS; Nahra, ME, 2004)
"Ganglion cysts are ubiquitous cystic lesions without synovial wall and inconstant communication with the articular cavity."	( Aubry, S; Kastler, B; Laborie, L; Lerais, JM; Puget, J; Sarlieve, P, 2006)
"While extraneural ganglion cysts are common and well known, intraneural ganglia are rare and misunderstood."	( Amrami, KK; Colbert, SH; Howe, BM; Spinner, RJ; Wang, H, 2012)
"Intraneural ganglion cysts are uncommon cystic lesions of peripheral nerves that are typically encountered in adults."	( Emery, KH; Johnson, N; Sorger, J; Squires, JH, 2014)
"Ganglion cysts are considered the most common tumor of the wrist and hand."	( Hass, A; Oron, A; Sarig, O, 2013)
"Ganglion cysts are common benign lesions in the hand and wrist."	( Majima, T; Motoda, N; Nanno, M; Tomori, Y, 2021)
"Ganglion cysts are the most common soft tissue tumor of the hand and wrist, affecting pediatric and adult populations."	( Al-Ani, S; Baldrighi, C; Jester, A; Oestreich, K; Ting, JWC; Zhou, J, 2022)
"Ganglion cysts are the most common mass of the hand or wrist."	( Bram, JT; Chang, B; Falk, DP; Fazal, FZ; Lin, IC; Shah, AS; Ty, JM, 2021)
"Ganglion cysts are most commonly encountered at the dorsal or volar aspects of the wrist, although cysts may arise from the flexor tendon sheath, interphalangeal joint, and extensor tendons."	( Benner, NR; Iannuzzi, NP; Zoller, SD, 2023)
"Ganglion cysts are benign lesions frequently seen in hand pathologies, but they are rarely seen in the foot and ankle."	( Azam, MT; Kennedy, JG; Ubillus, HA; Walls, RC; Walls, RJ, 2023)

Context

Excerpt	Reference
"In adults, ganglions have a female predilection and are commonly located in the dorsal wrist."	( Bram, JT; Chang, B; Falk, DP; Fazal, FZ; Lin, IC; Shah, AS; Ty, JM, 2021)

Treatment

Excerpt	Reference
"The majority of ganglion cysts can be treated nonoperatively but when surgery is performed a low recurrence rate can be anticipated."	( Bucchieri, JS; Nahra, ME, 2004)
"Trigger digit, Dupuytren's disease, and ganglion cysts are 3 common disorders treated by hand surgeons."	( Avery, EC; McCabe, SJ, 2023)

Research

Studies (164)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	19 (11.59)	23.3326
1990's	0 (0.00)	12.5806
2000's	51 (31.10)	18.1394
2010's	75 (45.73)	28.8240
2020's	19 (11.59)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
ammonium hydroxide	low	1	0
chlorine	low	1	0
histamine	low	3	0
acetaminophen	medium	2	1
bupivacaine	low	1	0
caffeine	low	1	0
celecoxib	low	1	0
amphetamine	low	1	0
gentamicin	low	1	0
guaifenesin	low	3	0
hexamethonium	low	1	0
ibuprofen	medium	1	1
lidocaine	low	1	0
indomethacin	low	1	0
iohexol	low	1	0
apnea	low	1	0
octopamine	low	2	0
procaine	low	2	0
propranolol	low	1	0
tranexamic acid	low	1	0
carbachol	low	1	0
estrone	low	1	0
methylprednisolone acetate	medium	2	1
pilocarpine	low	3	0
physostigmine	low	1	0
phenylephrine	medium	2	1
tyrosine	low	1	0
methylene blue	low	3	0
triamcinolone acetonide	medium	3	1
caramiphen	low	1	0
methylprednisolone	medium	2	1
cyclopentane	low	1	0
perfluorobutane	low	1	0
betamethasone	low	1	0
glycopyrrolate	medium	1	1
trimecaine	low	1	0
fluorescein	low	1	0
n-methylaspartate	low	1	0
trimethaphan	medium	1	1
gadolinium	low	3	0
barium chloride	low	1	0
trolamine salicylate	low	4	0
osmium tetroxide	low	1	0
cetylpyridinium chloride anhydrous	medium	1	1
glutamic acid	low	1	0
substance p	low	1	0
adenosine	low	1	0
plerixafor	low	1	0
betamethasone sodium phosphate	low	1	0
epibatidine	low	1	0
methotrexate	low	1	0
atropine	low	1	0
fibrin	low	1	0
y 27632	low	1	0
enkephalin, leucine	low	1	0
picibanil	low	2	0
polidocanol	low	2	0
indigo carmine	low	1	0
cystine	low	1	0
allatostatin 1	low	1	0
glyceryl 2-arachidonate	low	1	0
hydrocodone	medium	2	1
morphine	low	2	0
dexmedetomidine	medium	1	1
barium	low	1	0
silicon	low	1	0
gadolinium dtpa	low	4	0
orcokinin	low	2	0
glucagon-like peptide 1	low	1	0
incretins	low	1	0
sodium tetradecyl sulfate	low	2	0
vasoactive intestinal peptide	low	1	0
ascorbic acid	low	1	0
minocycline	low	1	0
allatotropin	low	1	0
peptide yy	low	1	0
chondroitin sulfates	low	1	0
cyclic gmp	low	1	0
eye	low	2	0

Protein Targets (943)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	16	0	0	16
ATAD5 protein, partial	10	0	0	10
GLS protein	12	0	0	12
Microtubule-associated protein tau	9	0	0	9
Smad3	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
thyroid stimulating hormone receptor	9	0	0	9
nuclear receptor subfamily 1, group I, member 3	11	0	0	11
progesterone receptor	14	0	0	14
EWS/FLI fusion protein	11	0	0	11
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
retinoid X nuclear receptor alpha	18	0	0	18
estrogen-related nuclear receptor alpha	21	0	0	21
estrogen nuclear receptor alpha	30	0	0	30
peroxisome proliferator activated receptor gamma	13	0	0	13
aryl hydrocarbon receptor	11	0	0	11
chromobox protein homolog 1	11	0	0	11
thyroid hormone receptor beta isoform 2	15	0	0	15
peripheral myelin protein 22	10	0	0	10
cytochrome P450 3A4 isoform 1	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	7	3	1	11
ATP-binding cassette sub-family C member 3	0	13	0	13
Multidrug resistance-associated protein 4	0	13	0	15
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	2	0	4
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	5	0	5
Voltage-dependent calcium channel gamma-2 subunit	12	0	0	12
Bile salt export pump	0	20	0	20
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	5	0	8
Carbonic anhydrase 2	0	5	1	10
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	1	0	2
Prostaglandin G/H synthase 1	0	6	0	7
Carbonic anhydrase 3	0	2	0	4
Cytochrome P450 3A4	0	3	1	4
Cytochrome P450 2D6	0	4	0	4
Cytochrome P450 2C9	0	7	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	7	3	1	11
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	7	3	1	11
Gamma-aminobutyric acid receptor subunit gamma-2	7	3	2	12
UDP-glucuronosyltransferase 1-6	0	0	0	1
Glutamate receptor 2	12	3	1	16
Gamma-aminobutyric acid receptor subunit alpha-5	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-3	7	3	1	11
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	3	0	5
Prostaglandin G/H synthase 1	0	4	0	5
Carbonic anhydrase 6	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-2	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-4	7	3	1	11
Gamma-aminobutyric acid receptor subunit gamma-3	7	3	1	11
Gamma-aminobutyric acid receptor subunit alpha-6	7	3	1	11
Carbonic anhydrase 5A, mitochondrial	0	2	0	4
Prostaglandin G/H synthase 2	0	5	2	9
Carbonic anhydrase 7	0	2	0	4
Nuclear receptor ROR-gamma	3	0	0	3
Cytochrome P450 2J2	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	7	4	2	13
Gamma-aminobutyric acid receptor subunit beta-3	7	3	1	11
Gamma-aminobutyric acid receptor subunit beta-2	7	3	2	12
Carbonic anhydrase 9	0	3	0	5
GABA theta subunit	7	3	1	11
Canalicular multispecific organic anion transporter 1	0	13	0	13
Carbonic anhydrase 15	0	3	0	5
Carbonic anhydrase 13	0	1	0	2
Gamma-aminobutyric acid receptor subunit epsilon	7	3	1	11
Carbonic anhydrase 14	0	2	0	4
Carbonic anhydrase 5B, mitochondrial	0	2	0	4
toxin B	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	12	0	0	12
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
AR protein	27	0	0	27
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	8	0	0	8
glucocorticoid receptor [Homo sapiens]	23	0	0	23
NPYLR7B	0	0	1	1
arylsulfatase A	11	0	0	11
IDH1	13	0	0	13
Histone H2A.x	6	0	0	6
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	4	0	0	4
flap endonuclease 1	5	0	0	5
nuclear receptor ROR-gamma isoform 1	6	0	0	6
survival motor neuron protein isoform d	5	0	0	5
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	3	0	3
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	6	3	10
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	6	1	10
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	4	4	10
Adenosine receptor A2b	0	1	1	4
Adenosine receptor A2b	0	3	1	5
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	3	9
Adenosine receptor A2a	0	5	1	10
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	1	1	2
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Solute carrier family 22 member 3	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	1	4
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	2	1	3
Substance-P receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	2	1	3
5-hydroxytryptamine receptor 1A	0	4	2	7
Cytochrome P450 2A5	0	1	0	1
Sodium-dependent dopamine transporter	0	3	0	3
5-hydroxytryptamine receptor 1B	0	3	1	4
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	1	1	2
5-hydroxytryptamine receptor 6	0	0	1	1
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	1	1	2
5-hydroxytryptamine receptor 4	0	0	1	1
Beta-2 adrenergic receptor	0	3	1	5
5-hydroxytryptamine receptor 3B	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
thioredoxin reductase	13	0	0	13
TDP1 protein	18	0	0	18
euchromatic histone-lysine N-methyltransferase 2	23	0	0	23
Bloom syndrome protein isoform 1	10	0	0	10
D(1A) dopamine receptor	5	0	0	5
lamin isoform A-delta10	16	0	0	16
neuropeptide S receptor isoform A	4	0	0	4
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	8	0	0	8
GLI family zinc finger 3	15	0	0	15
thioredoxin glutathione reductase	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
vitamin D (1,25- dihydroxyvitamin D3) receptor	13	0	0	13
nuclear factor erythroid 2-related factor 2 isoform 2	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 1	14	0	0	14
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
geminin	19	0	0	19
lethal factor (plasmid)	3	0	0	3
Polyphenol oxidase 2	0	1	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	3
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	3	2	6
Spike glycoprotein	9	0	0	9
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	6	0	0	6
pregnane X nuclear receptor	13	0	0	13
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	4	0	0	4
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	4	0	5
5-hydroxytryptamine receptor 4	0	4	0	4
Muscarinic acetylcholine receptor M2	0	8	5	17
Muscarinic acetylcholine receptor M4	0	5	3	11
Muscarinic acetylcholine receptor M1	0	8	2	15
Muscarinic acetylcholine receptor M3	0	8	2	14
Muscarinic acetylcholine receptor M4	0	8	1	13
Muscarinic acetylcholine receptor M5	0	8	1	13
Muscarinic acetylcholine receptor M5	0	6	3	12
Muscarinic acetylcholine receptor M2	0	9	1	15
Muscarinic acetylcholine receptor M1	0	7	6	17
Muscarinic acetylcholine receptor M1	0	1	2	4
Muscarinic acetylcholine receptor M3	0	7	4	14
Alpha-1D adrenergic receptor	0	3	1	5
5-hydroxytryptamine receptor 2C	0	4	1	5
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	3	0	1	5
5-hydroxytryptamine receptor 7	0	3	0	3
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	3	1	5
pregnane X receptor	2	0	0	2
farnesoid X nuclear receptor	12	0	0	12
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	12	0	0	12
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
thyroid hormone receptor beta isoform a	8	0	0	8
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	8	0	8
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
ORF73	0	0	1	1
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	2	3
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
phosphopantetheinyl transferase	9	0	0	9
thyroid stimulating hormone receptor	7	0	0	7
v-jun sarcoma virus 17 oncogene homolog (avian)	8	0	0	8
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
DNA polymerase kappa isoform 1	7	0	0	7
muscarinic acetylcholine receptor M1	5	0	0	5
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	4	0	4
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	3	0	4
Amine oxidase [flavin-containing] B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	3
Guanine deaminase	0	1	0	1
ATP-dependent phosphofructokinase	8	0	0	8
D	0	1	0	1
D(2) dopamine receptor	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	4	0	4
Chain A, Beta-lactamase	4	0	0	4
GALC protein	3	0	0	3
thyrotropin-releasing hormone receptor	4	0	0	4
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	3	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Delta-type opioid receptor	0	5	1	9
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Cruzipain	3	0	0	3
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
glp-1 receptor, partial	5	0	0	5
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
SMAD family member 2	9	0	0	9
USP1 protein, partial	7	0	0	7
PPM1D protein	3	0	0	3
SMAD family member 3	9	0	0	9
caspase 7, apoptosis-related cysteine protease	5	0	0	5
estrogen receptor 2 (ER beta)	10	0	0	10
G	6	0	0	6
cytochrome P450 2D6	7	0	0	7
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
67.9K protein	6	0	0	6
peroxisome proliferator-activated receptor delta	9	0	0	9
Carbonic anhydrase	0	1	0	1
Rac1 protein	0	0	1	1
caspase-3	5	0	0	5
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
activating transcription factor 6	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
Caspase-7	1	0	0	1
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
caspase-3	1	0	0	1
heat shock protein beta-1	9	0	0	9
Prostaglandin E synthase	0	2	0	2
Histone deacetylase 3	0	2	0	2
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	2	0	2
Interferon beta	7	0	0	7
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
Cellular tumor antigen p53	12	0	0	12
Procathepsin L	0	2	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Beta-3 adrenergic receptor	0	4	2	6
Alpha-1B adrenergic receptor	0	7	1	8
Calpain-2 catalytic subunit	0	1	0	1
D(1A) dopamine receptor	0	3	1	4
Prostaglandin G/H synthase 1	0	3	0	3
Sodium-dependent noradrenaline transporter	0	2	1	3
Cruzipain	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Sodium-dependent serotonin transporter	0	6	0	6
Sodium-dependent serotonin transporter	0	1	1	2
Delta-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	5	2	10
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Carbonic anhydrase	0	2	0	4
Alpha-1A adrenergic receptor	0	7	1	8
Urotensin-2 receptor	0	1	0	1
Carbonic anhydrase	0	1	0	4
Histone deacetylase 4	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	6	0	6
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	7	1	8
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Histone deacetylase 1	0	2	0	2
Mitogen-activated protein kinase 14	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	4
Carbonic anhydrase	0	1	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	2
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	2	0	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
Inositol hexakisphosphate kinase 1	6	0	0	6
Histone deacetylase 2	0	2	0	2
Carbonic anhydrase 4	0	2	0	3
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
ATPase family AAA domain-containing protein 5	9	0	0	9
Ataxin-2	10	0	0	10
Histone deacetylase 8	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
cytochrome P450 2C9, partial	6	0	0	6
Chain A, Ferritin light chain	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
vitamin D3 receptor isoform VDRA	5	0	0	5
Caspase-2	0	0	1	1
Inositol monophosphatase 1	3	0	0	3
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Alpha-1B adrenergic receptor	0	0	2	2
cytochrome P450 2D6 isoform 1	3	0	0	3
cellular tumor antigen p53 isoform a	2	0	0	2
cytochrome P450 2C19 precursor	3	0	0	3
cytochrome P450 2C9 precursor	3	0	0	3
Alpha-2A adrenergic receptor	0	3	5	9
Alpha-1A adrenergic receptor	0	1	2	3
Alpha-2C adrenergic receptor	0	3	4	8
Alpha-2B adrenergic receptor	0	2	1	3
Alpha-2C adrenergic receptor	0	2	1	3
Alpha-2A adrenergic receptor	0	2	1	3
Alpha-1D adrenergic receptor	0	5	1	6
Opioid receptor, delta 1b	0	2	0	2
Opioid receptor homologue	0	2	0	2
Proenkephalin-B	0	0	1	1
Kappa-type opioid receptor	0	3	1	5
Kappa-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	6	3	10
Delta-type opioid receptor	0	4	3	8
Kappa-type opioid receptor	0	3	0	3
Kappa-type opioid receptor	0	5	3	9
Mu-type opioid receptor	0	3	1	6
Mu-type opioid receptor	0	2	0	2
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
endonuclease IV	1	0	0	1
NFKB1 protein, partial	5	0	0	5
nonstructural protein 1	4	0	0	4
hexokinase-4 isoform 1	2	0	0	2
peripheral myelin protein 22 isoform 1	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
glucokinase regulatory protein	2	0	0	2
DNA polymerase iota isoform a (long)	7	0	0	7
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
Estrogen receptor	0	2	1	4
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Steryl-sulfatase	0	1	0	1
Aromatase	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Androgen receptor	0	4	0	4
Alpha-synuclein	1	1	0	2
5-hydroxytryptamine receptor 2B	0	4	1	5
Solute carrier organic anion transporter family member 1A1	0	2	0	2
TAR DNA-binding protein 43	6	0	0	6
Cytochrome P450 1B1	0	1	0	1
Estrogen receptor beta	0	1	1	3
Ghrelin O-acyltransferase	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	7	0	0	7
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
transcriptional regulator ERG isoform 3	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Glucagon-like peptide 1 receptor	0	0	1	1
Glucagon-like peptide 1 receptor	0	1	1	2
Glucagon receptor	0	0	1	1
Glucagon receptor	0	0	1	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Integrin beta-3	1	0	1	2
Integrin alpha-IIb	1	0	1	2
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 3	0	3	1	4
Glutamate receptor 4	0	3	1	4
Glutamate receptor ionotropic, kainate 1	0	3	1	4
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	4	2	9
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	3	1	4
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	2	9
Glutamate receptor ionotropic, NMDA 2B	0	4	2	9
Glutamate receptor ionotropic, NMDA 2C	0	4	2	9
Glutamate receptor ionotropic, kainate 4	0	3	0	3
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	4	2	9
Glutamate receptor ionotropic, kainate 5	0	3	0	3
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	4	2	9
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	2	9
alpha-galactosidase	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 1	0	1	1	2
Cannabinoid receptor 2	0	1	1	2
Cannabinoid receptor 2	0	1	0	1
ras-related protein Rab-9A	3	0	0	3
M-phase phosphoprotein 8	5	0	0	5
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
apical membrane antigen 1, AMA1	1	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 3	0	1	0	2
Plasma kallikrein	0	0	0	2
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	1	2	3
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	1	2	3
Histamine H1 receptor	0	2	1	3
Histamine H1 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	1	0	2
Solute carrier family 22 member 2	0	1	0	2
Histamine H3 receptor	0	1	2	3
Mas-related G-protein coupled receptor member X2	0	0	3	3
Luciferase	6	0	0	6
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
muscleblind-like protein 1 isoform 1	5	0	0	5
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Fatty acid-binding protein, liver	0	1	0	1
Albumin	0	2	4	6
Albumin	0	0	1	1
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	4
UDP-glucuronosyltransferase 2B7	0	0	0	1
Caspase-1	0	1	0	2
Substance-P receptor	0	3	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	2
Aldo-keto reductase family 1 member C3	0	3	0	3
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Solute carrier family 22 member 6	0	2	0	3
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 8	0	2	0	3
Solute carrier family 22 member 6	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
histone deacetylase 9 isoform 3	2	0	0	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
interleukin 8	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
glucocerebrosidase	1	0	0	1
Parkin	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Interleukin-8	0	1	0	1
Androgen receptor	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	1	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
dopamine D1 receptor	4	0	0	4
ClpP	1	0	0	1
15-lipoxygenase, partial	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
DNA polymerase eta isoform 1	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	3	0	3
Chain E, Fibrin beta chain	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
Fumarate hydratase	3	0	0	3
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
polyprotein	3	0	0	3
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
huntingtin isoform 2	2	0	0	2
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Stromelysin-1	0	1	0	1
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Acetylcholinesterase	0	3	0	4
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
POU domain, class 2, transcription factor 1	0	0	0	2
5-hydroxytryptamine receptor 3A	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Beta-2 adrenergic receptor	0	2	2	4
Beta-1 adrenergic receptor	0	2	2	4
Beta-1 adrenergic receptor	0	3	1	5
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-1A adrenergic receptor	0	2	3	6
Alpha-1B adrenergic receptor	0	1	2	4
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	2	0	3
Cholinesterase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
C-X-C chemokine receptor type 4	0	1	0	1
Atypical chemokine receptor 3	0	0	1	1
C-C chemokine receptor type 2	0	1	0	1
C-X-C chemokine receptor type 4	0	2	0	4
Beta-1 adrenergic receptor	0	1	1	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	3
Cytochrome P450 2C8	0	1	0	1
D(2) dopamine receptor	0	1	1	2
D(3) dopamine receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 2A	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
Cytochrome P450 2C19	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Vasopressin V1a receptor	0	1	1	2
5-hydroxytryptamine receptor 6	0	2	1	3
Beta-2 adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	2	0	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	1	0	1
Chain B, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, Rho-associated protein kinase 1	0	1	0	1
Rho-associated protein kinase 2	0	2	0	2
Ribosomal protein S6 kinase alpha-5	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
C-C motif chemokine 2	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
cAMP-dependent protein kinase catalytic subunit gamma	0	1	0	1
cAMP-dependent protein kinase catalytic subunit beta	0	1	0	1
Rho-associated protein kinase 1	0	2	0	2
Serine/threonine-protein kinase N2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

chemdatabank.com