Trichotillomania

Synonym
Trichotillomania

Excerpt	Reference
"Trichotillomania is characterized by chronic hair-pulling resulting in noticeable hair loss."	( Lewine, RJ; Ninan, PT; Risch, SC; Rothbaum, BO; Stipetic, M, 1992)
"Trichotillomania is a neglected neuropsychiatric disorder that only recently has received research attention."	( Leonard, HL; Swedo, SE, 1992)
"Trichotillomania is characterized by an inability to resist urges to pull out hair."	( Tynes, LL; Winstead, DK, 1992)
"Trichotillomania is a form of traction alopecia resulting from compulsive repetitive removal of one's own hair."	( Camisa, C; Dimino-Emme, L, 1991)
"Trichotillomania is seen in normal children with a variety of psychiatric conditions (Krishnan, 1985)."	( Carr, S; Weller, EB; Weller, RA, 1989)
"Trichotillomania is a chronic illness that may be difficult to treat."	( Aronowitz, B; Cohen, LJ; Hollander, E; Rosen, J; Simeon, D; Spadaccini, E; Stein, DJ, 1995)
"Tonsure trichotillomania is a subtype of trichotillomania in which the scalp exhibits a tonsural pattern of alopecia over the crown, extending to the frontal margin and sparing the lateral margins and the nape of the neck."	( Davis-Daneshfar, A; Trüeb, RM, 1995)
"Trichotillomania is characterized by recurrent pulling out of one's hair for pleasure, gratification, or relief of tension that results in noticeable hair loss."	( Silva, H, 1997)
"Trichotillomania is a chronic psychiatric condition characterised by uncontrollable, self-inflicted, hair pulling, resulting in noticeable hair loss."	( Ko, SM, 1999)
"Trichotillomania is categorized as an impulse control disorder in DSM-IV and is considered by some to be closely related to Obsessive Compulsive Disorder (OCD)."	( Farvolden, P; Mancini, C; Oakman, JM; Van Ameringen, M, 1999)
"Trichotillomania is a neglected psychiatric disorder with dermatologic expression that has only recently received research attention."	( Hautmann, G; Hercogova, J; Lotti, T, 2002)
"Trichotillomania is a psychiatric condition characterized by chronic hair pulling."	( Dougherty, DD; Jenike, MA; Keuthen, NJ; Loh, R, 2006)
"Trichotillomania is a psychiatric condition characterized by compulsive hair pulling."	( Bloch, MH; Coric, V; Dombrowski, P; Kelmendi, B; Landeros-Weisenberger, A; Leckman, JF; Nudel, J; Pittenger, C; Wegner, R, 2007)
"Trichotillomania is characterized by repetitive hair pulling that causes noticeable hair loss."	( Grant, JE; Kim, SW; Odlaug, BL, 2009)
"Trichotillomania is characterized by repetitive pulling causing noticeable hair loss."	( Chamberlain, SR; Grant, JE; Kim, SW; Odlaug, BL, 2011)
"Trichotillomania is characterized by repetitive compulsive hair pulling that leads to noticeable hair loss."	( Peabody, T; Reitz, S; Smith, J; Teti, B, 2013)
"The neurobiology of Trichotillomania is poorly understood, although there is increasing evidence to suggest that TTM may involve alterations of reward processing."	( Damoiseaux, JS; Greicius, MD; Molfino, MJ; Shirer, WR; Tenison, C; White, MP, 2013)
"The management of trichotillomania is challenging."	( Özcan, D; Seçkin, D, 2016)
"Trichotillomania is characterized by repetitive pulling that causes noticeable hair loss."	( Grant, JE; Leppink, EW; Redden, SA, 2017)
"Trichotillomania is a relatively understudied psychiatric disorder."	( Bartley, MM; Grant, JE; Lapid, MI, 2017)
"Trichotillomania is several times more common in women and has peak onset around puberty."	( Chamberlain, SR; Grant, JE, 2018)

Excerpt	Reference
"Trichotillomania has been considered as part of the obsessive-compulsive disorder spectrum; however, trichotillomania treatment with obsessive-compulsive disorder medications has largely been unsuccessful."	( Bennett, M; Mancini, C; Oakman, J; Patterson, B; Van Ameringen, M, 2010)

Excerpt	Reference
"In general, effective treatments for trichotillomania have been elusive."	( Jones, JS; Molcho, A; Stanley, B; Stanley, M; Winchel, RM, 1992)
"Four consecutive patients treated for trichotillomania (hair pulling) with clomipramine reported initially dramatic reductions in symptoms."	( Bronson, SS; Flynn, TM; Ibe, IO; Kitchen, AD; Krojanker, DN; Pollard, CA, 1991)
"The efficacy of fluoxetine in the treatment of trichotillomania was not demonstrated in this study."	( Streichenwein, SM; Thornby, JI, 1995)
"The current study describes successful treatment of trichotillomania in a young autistic girl, using combined clomipramine and behavioral therapy."	( Eastman, LE; Holttum, JR; Lubetsky, MJ, 1994)
"Imipramine was unsuccessful in treating trichotillomania and showed limited success in alleviating depression."	( Sheikha, SH; Wagner, KD; Wagner, RF, 1993)
"Evidence for the efficacy of treatment of trichotillomania with drugs typically used for OCD is equivocal."	( Farvolden, P; Mancini, C; Oakman, JM; Van Ameringen, M, 1999)
"Data on the pharmacologic treatment of trichotillomania are limited to conflicting studies of serotonergic medications."	( Grant, JE; Kim, SW; Odlaug, BL, 2009)
"Pharmacological treatment data for trichotillomania are limited."	( Chamberlain, SR; Grant, JE; Kim, SW; Odlaug, BL, 2011)
"Data on the pharmacological treatment of trichotillomania are limited, with no clear first-line agent."	( Grant, JE; Leppink, EW; Redden, SA, 2017)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	15 (6.52)	23.3326
1990's	74 (32.17)	12.5806
2000's	59 (25.65)	18.1394
2010's	64 (27.83)	28.8240
2020's	18 (7.83)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	low	27	0
bupropion	low	2	0
histamine	low	1	0
inositol	medium	2	1
melatonin	low	1	0
1-(3-chlorophenyl)piperazine	medium	1	1
n-methyl-3,4-methylenedioxyamphetamine	low	1	0
hydroxyindoleacetic acid	low	2	0
amitriptyline	low	1	0
buspirone	low	2	0
citalopram	medium	9	3
clomipramine	medium	35	7
clonazepam	low	1	0
clonidine	low	1	0
desipramine	medium	4	3
amphetamine	low	1	0
diazepam	low	1	0
valproic acid	low	3	0
fentanyl	low	1	0
fluoxetine	medium	32	8
haloperidol	medium	5	1
imipramine	low	4	0
isocarboxazid	low	1	0
lamotrigine	low	1	0
methylphenidate	low	4	0
minoxidil	low	2	0
modafinil	medium	2	1
pirenzepine	medium	4	1
riluzole	low	1	0
risperidone	medium	4	1
ropinirole	low	2	0
trazodone	low	2	0
carbostyril	medium	3	1
fluocinolone acetonide	low	2	0
tryptophan	low	1	0
triamcinolone acetonide	low	1	0
cyclohexanol	medium	2	1
1-naphthylamine	low	2	0
lithium carbonate	medium	3	1
s,n,n'-tripropylthiocarbamate	low	5	0
pimozide	medium	2	1
barium sulfate	low	2	0
glutamic acid	low	2	0
paroxetine	low	8	0
pergolide	low	1	0
atomoxetine hydrochloride	low	1	0
finasteride	low	1	0
aripiprazole	medium	6	1
venlafaxine hydrochloride	medium	2	1
fluorodeoxyglucose f18	low	1	0
sertraline	medium	10	1
nsc-172755	low	1	0
fluocinolone	low	2	0
deoxyglucose	low	1	0
pramipexole	low	2	0
reboxetine	low	1	0
biotin	low	1	0
oxytocin	low	1	0
griseofulvin	low	1	0
mometasone furoate	low	1	0
cocaine	low	2	0
buprenorphine	low	2	0
capsaicin	low	1	0
D-fructopyranose	medium	1	1
pica	low	12	0
lithium	medium	2	1
rasagiline	low	1	0
isotretinoin	low	1	0
phenylephrine hydrochloride	low	2	0
nalmefene	low	1	0
topiramate	medium	1	1
bimatoprost	low	1	0
cloprostenol	low	1	0
fluvoxamine	medium	8	3
heroin	low	1	0
lisdexamfetamine dimesylate	low	1	0
ants	low	1	0
sodium ethylxanthate	low	1	0
quetiapine fumarate	low	2	0
deoxyguanosine	low	1	0
olanzapine	medium	10	2
8-hydroxy-2'-deoxyguanosine	low	1	0

Protein Targets (935)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
5-hydroxytryptamine receptor 3E	0	4	0	4
acetylcholinesterase	10	0	0	10
TDP1 protein	33	0	0	33
cytochrome P450 2D6	27	0	0	27
v-jun sarcoma virus 17 oncogene homolog (avian)	16	0	0	16
cytochrome P450 2D6 isoform 1	17	0	0	17
cellular tumor antigen p53 isoform a	5	0	0	5
cytochrome P450 2C19 precursor	6	0	0	6
cytochrome P450 2C9 precursor	8	0	0	8
thyroid hormone receptor beta isoform a	7	0	0	7
thyroid hormone receptor beta isoform 2	29	0	0	29
huntingtin isoform 2	5	0	0	5
peripheral myelin protein 22	23	0	0	23
cytochrome P450 3A4 isoform 1	16	0	0	16
muscarinic acetylcholine receptor M1	18	0	0	18
Gamma-aminobutyric acid receptor subunit pi	16	3	1	20
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	0	0	8
ATP-binding cassette sub-family C member 3	0	30	0	30
Multidrug resistance-associated protein 4	0	30	0	30
5-hydroxytryptamine receptor 3B	0	4	0	4
Bile salt export pump	0	45	0	45
Beta-1 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	15	9	24
5-hydroxytryptamine receptor 2C	0	24	1	25
D(2) dopamine receptor	0	29	7	39
5-hydroxytryptamine receptor 2A	0	25	1	26
Gamma-aminobutyric acid receptor subunit beta-1	16	3	1	20
Alpha-1B adrenergic receptor	0	21	2	23
Gamma-aminobutyric acid receptor subunit delta	16	3	1	20
Gamma-aminobutyric acid receptor subunit gamma-2	16	3	1	20
D	0	17	0	17
5-hydroxytryptamine receptor 1A	0	31	2	33
Gamma-aminobutyric acid receptor subunit alpha-5	16	3	1	20
Gamma-aminobutyric acid receptor subunit alpha-3	16	3	1	20
Gamma-aminobutyric acid receptor subunit gamma-1	16	3	1	20
Gamma-aminobutyric acid receptor subunit alpha-2	16	3	1	20
Alpha-1D adrenergic receptor	0	18	2	20
5-hydroxytryptamine receptor 2A	0	31	4	35
5-hydroxytryptamine receptor 2C	0	29	2	31
Gamma-aminobutyric acid receptor subunit alpha-4	16	3	1	20
Gamma-aminobutyric acid receptor subunit gamma-3	16	3	1	20
5-hydroxytryptamine receptor 1B	0	24	1	25
5-hydroxytryptamine receptor 1D	0	12	1	13
Gamma-aminobutyric acid receptor subunit alpha-6	16	3	1	20
5-hydroxytryptamine receptor 1F	0	12	1	13
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	23	1	24
Sodium-dependent serotonin transporter	0	41	6	47
5-hydroxytryptamine receptor 7	0	13	1	14
5-hydroxytryptamine receptor 7	0	9	0	9
Alpha-1B adrenergic receptor	0	6	1	7
Glutamate receptor ionotropic, NMDA 1	0	9	1	12
5-hydroxytryptamine receptor 2B	0	28	1	29
Alpha-1A adrenergic receptor	0	25	3	28
5-hydroxytryptamine receptor 3A	0	6	0	6
Histamine H2 receptor	14	5	1	24
5-hydroxytryptamine receptor 6	0	23	0	23
Beta-2 adrenergic receptor	0	1	0	1
D(2) dopamine receptor	0	26	3	30
Gamma-aminobutyric acid receptor subunit alpha-1	16	3	1	20
Gamma-aminobutyric acid receptor subunit beta-3	16	3	1	20
Gamma-aminobutyric acid receptor subunit beta-2	16	3	1	20
Glutamate receptor ionotropic, NMDA 2A	0	9	1	12
Glutamate receptor ionotropic, NMDA 2B	0	10	1	13
Glutamate receptor ionotropic, NMDA 2C	0	9	1	12
Glutamate receptor ionotropic, NMDA 2D	0	9	1	12
5-hydroxytryptamine receptor 3D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	9	1	12
5-hydroxytryptamine receptor 3C	0	4	0	4
GABA theta subunit	16	3	1	20
Canalicular multispecific organic anion transporter 1	0	28	0	28
Gamma-aminobutyric acid receptor subunit epsilon	16	3	1	20
Glutamate receptor ionotropic, NMDA 3A	0	9	1	12
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	10	0	0	10
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
RAR-related orphan receptor gamma	25	0	0	25
GLI family zinc finger 3	30	0	0	30
AR protein	34	0	0	34
aldehyde dehydrogenase 1 family, member A1	16	0	0	16
thyroid stimulating hormone receptor	13	0	0	13
estrogen receptor 2 (ER beta)	15	0	0	15
nuclear receptor subfamily 1, group I, member 3	24	0	0	24
progesterone receptor	20	0	0	20
glucocorticoid receptor [Homo sapiens]	28	0	0	28
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
estrogen-related nuclear receptor alpha	29	0	0	29
pregnane X nuclear receptor	26	0	0	26
estrogen nuclear receptor alpha	39	0	0	39
aryl hydrocarbon receptor	10	0	0	10
thyroid stimulating hormone receptor	16	0	0	16
activating transcription factor 6	8	0	0	8
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	13	0	0	13
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	23	0	0	23
Voltage-dependent calcium channel gamma-2 subunit	14	0	0	14
Glutamate receptor 2	14	2	2	18
Kelch-like ECH-associated protein 1	0	0	1	1
Histone acetyltransferase KAT8	0	1	0	1
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
dopamine D1 receptor	4	0	0	4
15-lipoxygenase, partial	5	0	0	5
pregnane X receptor	4	0	0	4
phosphopantetheinyl transferase	12	0	0	12
USP1 protein, partial	20	0	0	20
NFKB1 protein, partial	9	0	0	9
Microtubule-associated protein tau	10	0	0	10
Thrombopoietin	6	0	0	6
regulator of G-protein signaling 4	17	0	0	17
retinoid X nuclear receptor alpha	19	0	0	19
farnesoid X nuclear receptor	14	0	0	14
vitamin D (1,25- dihydroxyvitamin D3) receptor	15	0	0	15
arylsulfatase A	12	0	0	12
euchromatic histone-lysine N-methyltransferase 2	37	0	0	37
Bloom syndrome protein isoform 1	10	0	0	10
D(1A) dopamine receptor	19	0	0	19
heat shock protein beta-1	8	0	0	8
flap endonuclease 1	5	0	0	5
geminin	32	0	0	32
survival motor neuron protein isoform d	13	0	0	13
Histone deacetylase 3	0	3	0	3
Solute carrier family 22 member 6	0	2	0	2
Histone deacetylase 4	0	3	0	3
Guanine nucleotide-binding protein G	2	0	0	2
Histone deacetylase 1	0	3	0	3
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Ataxin-2	22	0	0	22
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
ATP-dependent phosphofructokinase	18	0	0	18
thioredoxin reductase	21	0	0	21
GLS protein	15	0	0	15
cytochrome P450 family 3 subfamily A polypeptide 4	20	0	0	20
chromobox protein homolog 1	19	0	0	19
atrial natriuretic peptide receptor 2 precursor	8	0	0	8
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
Solute carrier family 22 member 1	0	15	0	17
Voltage-dependent L-type calcium channel subunit alpha-1F	0	8	0	8
5-hydroxytryptamine receptor 4	0	24	0	24
Albumin	0	0	8	8
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	21	0	21
Muscarinic acetylcholine receptor M2	0	18	0	18
Muscarinic acetylcholine receptor M4	0	18	0	18
Muscarinic acetylcholine receptor M1	0	7	0	7
Muscarinic acetylcholine receptor M3	0	6	0	6
Muscarinic acetylcholine receptor M4	0	6	0	6
Muscarinic acetylcholine receptor M5	0	7	0	7
Muscarinic acetylcholine receptor M5	0	21	0	21
Alpha-2A adrenergic receptor	0	25	1	26
Muscarinic acetylcholine receptor M2	0	6	0	6
Muscarinic acetylcholine receptor M1	0	21	2	24
Angiotensin-converting enzyme	0	18	0	18
Alpha-2B adrenergic receptor	0	28	1	29
Alpha-2C adrenergic receptor	0	25	1	26
Muscarinic acetylcholine receptor M3	0	21	0	21
D(1A) dopamine receptor	0	18	2	22
D(1B) dopamine receptor	0	6	1	9
UDP-glucuronosyltransferase 1A4	0	1	0	6
Sodium-dependent noradrenaline transporter	0	40	5	45
Histamine H2 receptor	0	14	4	18
Alpha-1D adrenergic receptor	0	25	1	26
5-hydroxytryptamine receptor 6	0	7	1	8
Histamine H1 receptor	0	9	1	10
5-hydroxytryptamine receptor 5A	0	7	1	8
5-hydroxytryptamine receptor 5B	0	7	1	8
Histamine H1 receptor	0	26	4	30
D(3) dopamine receptor	0	25	6	35
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 4 subunit alpha	0	7	0	9
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 3A	0	7	1	8
D(1A) dopamine receptor	10	1	0	11
5-hydroxytryptamine receptor 7	0	9	0	9
Voltage-dependent N-type calcium channel subunit alpha-1B	0	4	0	4
Sodium channel protein type 7 subunit alpha	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	8	0	8
Sodium-dependent dopamine transporter	0	28	4	32
Potassium voltage-gated channel subfamily H member 2	0	34	0	34
Voltage-dependent L-type calcium channel subunit alpha-1S	0	8	0	8
Voltage-dependent L-type calcium channel subunit alpha-1C	0	9	0	9
Sodium channel protein type 5 subunit alpha	0	9	0	9
Sodium channel protein type 9 subunit alpha	0	8	0	8
Sigma non-opioid intracellular receptor 1	0	8	1	9
5-hydroxytryptamine receptor 4	0	7	1	8
Nuclear receptor subfamily 3 group C member 3	0	17	0	17
Sodium channel protein type 2 subunit alpha	0	6	0	6
Sigma non-opioid intracellular receptor 1	0	29	0	29
5-hydroxytryptamine receptor 3B	0	7	1	8
Sodium channel protein type 3 subunit alpha	0	6	0	6
Sodium channel protein type 11 subunit alpha	0	5	0	5
Sodium channel protein type 8 subunit alpha	0	5	0	5
Histamine H3 receptor	0	8	2	10
Sodium channel protein type 10 subunit alpha	0	6	0	6
Solute carrier family 22 member 3	0	2	0	2
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	2	0	2
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Sodium-dependent dopamine transporter	0	21	1	22
Beta-2 adrenergic receptor	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	10	0	10
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
SMAD family member 2	7	0	0	7
Fumarate hydratase	9	0	0	9
PPM1D protein	3	0	0	3
SMAD family member 3	7	0	0	7
EWS/FLI fusion protein	13	0	0	13
G	12	0	0	12
polyprotein	9	0	0	9
67.9K protein	8	0	0	8
peroxisome proliferator-activated receptor delta	15	0	0	15
peroxisome proliferator activated receptor gamma	17	0	0	17
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
lysosomal alpha-glucosidase preproprotein	4	0	0	4
mu-type opioid receptor isoform MOR-1	0	0	4	4
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	23	0	0	23
transcriptional regulator ERG isoform 3	4	0	0	4
nuclear receptor ROR-gamma isoform 1	9	0	0	9
histone acetyltransferase KAT2A isoform 1	7	0	0	7
5-hydroxytryptamine receptor 2A	0	0	4	4
neuropeptide S receptor isoform A	3	0	0	3
Solute carrier family 22 member 2	0	6	0	8
5-hydroxytryptamine receptor 3A	0	1	1	2
Interferon beta	14	0	0	14
HLA class I histocompatibility antigen, B alpha chain	12	0	0	12
Cellular tumor antigen p53	23	0	0	23
ATP-dependent translocase ABCB1	0	9	0	14
Cytochrome P450 3A4	0	10	0	12
Neuronal acetylcholine receptor subunit alpha-4	3	2	0	5
Neuronal acetylcholine receptor subunit beta-2	3	2	0	5
D(4) dopamine receptor	0	11	3	17
D(4) dopamine receptor	0	13	0	13
Histamine H1 receptor	0	5	2	8
Alpha-1A adrenergic receptor	0	8	1	9
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Spike glycoprotein	21	1	3	25
Inositol monophosphatase 1	9	0	0	9
Multidrug and toxin extrusion protein 2	0	5	0	5
Inositol hexakisphosphate kinase 1	12	0	0	12
Multidrug and toxin extrusion protein 1	0	6	0	6
cytochrome P450 2C9, partial	12	0	0	12
glp-1 receptor, partial	8	0	0	8
IDH1	11	0	0	11
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
apical membrane antigen 1, AMA1	3	0	0	3
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
vitamin D3 receptor isoform VDRA	8	0	0	8
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Kappa-type opioid receptor	0	7	0	8
Kappa-type opioid receptor	0	9	1	14
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Integrin alpha-5	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	3	0	6
Neuronal acetylcholine receptor subunit beta-2	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	1	0	2
Cytochrome P450 2B6	0	0	1	3
UDP-glucuronosyltransferase 1A1	0	2	0	3
Neuronal acetylcholine receptor subunit beta-4	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Cytochrome P450 2C19	0	8	0	9
UDP-glucuronosyltransferase 2B10	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	2
Acetylcholine receptor subunit delta	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
Bile salt export pump	0	5	0	5
Beta-2 adrenergic receptor	0	3	0	3
Angiotensin-converting enzyme	0	1	0	1
Beta-1 adrenergic receptor	0	3	0	3
D(3) dopamine receptor	0	15	1	16
Alpha-2B adrenergic receptor	0	15	0	15
D(2) dopamine receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	15	0	15
Alpha-2A adrenergic receptor	0	15	0	15
D(1B) dopamine receptor	0	11	0	11
Beta-3 adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D	0	5	0	5
Lysosomal alpha-glucosidase	0	1	0	1
glucocerebrosidase	2	0	0	2
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	19	0	0	19
mitogen-activated protein kinase 1	13	0	0	13
DNA polymerase iota isoform a (long)	9	0	0	9
transient receptor potential cation channel subfamily V member 1	2	0	0	2
lamin isoform A-delta10	28	0	0	28
Transient receptor potential cation channel subfamily V member 1	0	4	1	5
Lysine-specific histone demethylase 1A	0	2	0	2
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Cytochrome P450 1A2	0	3	1	5
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cannabinoid receptor 1	0	3	1	5
Acetylcholinesterase	0	7	0	7
Prostaglandin G/H synthase 1	0	3	0	3
Cannabinoid receptor 2	0	3	1	5
Nuclear receptor ROR-gamma	4	0	0	4
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
Chain A, Beta-lactamase	8	0	0	8
Vpr	2	0	0	2
Major prion protein	0	0	4	4
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 2 subunit alpha	0	6	0	6
Sodium channel protein type 3 subunit alpha	0	3	0	3
Cytochrome P450 2C9	0	11	0	11
Cytochrome P450 2J2	0	7	0	7
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	3	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, serum paraoxonase	0	1	0	1
DNA polymerase kappa isoform 1	4	0	0	4
Carbonic anhydrase 12	0	3	0	6
Carbonic anhydrase 1	0	5	0	9
Carbonic anhydrase 2	0	5	1	11
Carbonic anhydrase 3	0	3	0	5
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 4	0	3	0	6
Carbonic anhydrase 6	0	3	0	6
Carbonic anhydrase 5A, mitochondrial	0	3	1	7
Carbonic anhydrase 7	0	3	0	6
Carbonic anhydrase 9	0	3	0	6
Carbonic anhydrase 13	0	2	0	3
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 14	0	3	0	6
Carbonic anhydrase 5B, mitochondrial	0	3	0	6
Proteasome subunit beta type-11	0	0	0	1
ATAD5 protein, partial	14	0	0	14
Smad3	5	0	0	5
caspase 7, apoptosis-related cysteine protease	8	0	0	8
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	2
caspase-3	8	0	0	8
Adenylate cyclase type 1	0	3	0	3
Histone H2A.x	6	0	0	6
Caspase-7	6	0	0	6
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
caspase-3	6	0	0	6
histone deacetylase 9 isoform 3	2	0	0	2
ras-related protein Rab-9A	8	0	0	8
M-phase phosphoprotein 8	7	0	0	7
lethal factor (plasmid)	5	0	0	5
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	1	3	4
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Potassium channel subfamily K member 2	0	4	2	6
Epidermal growth factor receptor	0	1	0	1
Albumin	0	1	3	5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Integrin beta-3	3	0	1	4
Tyrosine-protein kinase Fyn	0	1	0	1
Procathepsin L	0	1	3	4
Integrin alpha-IIb	3	0	1	4
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Replicase polyprotein 1ab	0	1	3	4
Cytochrome P450 2D6	0	15	1	18
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Sphingomyelin phosphodiesterase	0	2	0	2
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
Adenylate cyclase type 3	0	3	0	3
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	4	0	4
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	2	0	4
Mu-type opioid receptor	0	10	5	18
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	9	3	15
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	2	3
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	1	3	4
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
Sodium-dependent noradrenaline transporter	0	4	0	4
Tryptophan 5-hydroxylase 1	0	4	0	4
Aldo-keto reductase family 1 member B1	0	3	0	3
Aromatase	0	1	0	1
Sodium-dependent serotonin transporter	0	17	3	21
Sigma intracellular receptor 2	0	6	0	6
Sodium-dependent serotonin transporter	0	4	0	4
Sodium-dependent dopamine transporter	0	6	0	6
Transporter	0	17	0	17
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Trypanothione reductase	0	1	0	1
Envelope glycoprotein	0	0	4	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	6	0	6
Gamma-aminobutyric acid receptor subunit delta	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	2	8
Gamma-aminobutyric acid receptor subunit beta-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	6	1	7
Translocator protein	0	2	0	2
Translocator protein	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	6	2	8
Gamma-aminobutyric acid receptor subunit alpha-3	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	6	1	7
Gamma-aminobutyric acid receptor subunit beta-2	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	6	0	6
Gamma-aminobutyric acid receptor subunit epsilon	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit theta	0	6	0	6
Chain A, Ferritin light chain	3	0	0	3
Chain A, Cruzipain	3	0	0	3
Beta-1 adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 3	0	5	0	6
Alpha-1A adrenergic receptor	0	0	1	1
Amine oxidase [flavin-containing] A	0	6	0	6
Amine oxidase [flavin-containing] B	0	6	0	6
Adenosine receptor A2b	0	0	1	1
Adenosine receptor A2a	0	0	1	2
Alpha-2B adrenergic receptor	0	0	0	1
Delta-type opioid receptor	0	6	1	8
Mu-type opioid receptor	0	6	1	8
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	5	0	7
Nischarin	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	1	2
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostacyclin receptor	0	1	0	1
Prostaglandin D2 receptor	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Amyloid-beta precursor protein	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Liver carboxylesterase 1	0	1	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
Deoxycytidine kinase	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Histamine H3 receptor	0	1	0	1
Solute carrier family 22 member 2	0	3	0	5
Solute carrier family 22 member 4	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Alpha-1-acid glycoprotein 1	0	0	0	1
Translocator protein	0	1	1	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
ATPase family AAA domain-containing protein 5	11	0	0	11
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Histamine H3 receptor	0	1	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Transient receptor potential cation channel subfamily A member 1	0	0	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Glutamate receptor 1	0	2	2	4
Glutamate receptor 3	0	2	2	4
Glutamate receptor 4	0	2	2	4
Cannabinoid receptor 1	0	2	1	3
Glycine receptor subunit alpha-1	0	0	3	3
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	1	2
N-arachidonyl glycine receptor	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoglyceride lipase	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Cannabinoid receptor 2	0	2	0	2
G-protein coupled receptor 55	0	1	1	2
Luciferase	7	0	0	7
Delta-type opioid receptor	0	6	1	7
Mu-type opioid receptor	0	7	2	9
Kappa-type opioid receptor	0	4	1	5
Mu-type opioid receptor	0	3	1	5
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	0	1	0	1
Androgen receptor	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
Glucocorticoid receptor	0	5	0	5
Glycine receptor subunit alpha-1	0	4	0	4
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Cytochrome P450 2C8	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	1	0	1
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Transporter	0	5	0	5
Cytochrome P450 1A2	0	2	0	2
thioredoxin glutathione reductase	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Excitatory amino acid transporter 4	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Heme oxygenase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
nonstructural protein 1	4	0	0	4
peripheral myelin protein 22 isoform 1	9	0	0	9
Cocaine esterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	3
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Adenosine receptor A1	0	2	0	3
C-8 sterol isomerase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	3	0	3
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
TAR DNA-binding protein 43	7	0	0	7
5-hydroxytryptamine receptor 4	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	2
Macrophage migration inhibitory factor	0	2	0	2
5-hydroxytryptamine receptor 1D	0	1	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	2	0	3
Carbonic anhydrase 15	0	2	0	4
Carbonic anhydrase 13	0	2	0	5
Histamine H4 receptor	0	4	3	7
Carboxylic ester hydrolase	0	0	0	1
endonuclease IV	2	0	0	2
hypothetical protein, conserved	1	0	0	1
alpha-galactosidase	1	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
Sodium/myo-inositol cotransporter 2	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Parkin	2	0	0	2
serine/threonine-protein kinase PLK1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
Ornithine decarboxylase	0	0	0	1
Adenosine receptor A3	0	2	0	2
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Mitogen-activated protein kinase 14	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Olfactory receptor 51E2	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
DNA polymerase beta	1	0	0	1
Progesterone receptor	0	0	2	2
interleukin 8	1	0	0	1
ClpP	1	0	0	1
Cytochrome P450 1A1	0	1	0	1
Myeloperoxidase	0	3	0	3
Cholinesterase	0	2	0	2
Cytochrome P450 2C11	0	1	0	1
Aromatase	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Cholinesterase	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
isocitrate dehydrogenase 1, partial	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Trace amine-associated receptor 1	0	0	1	1
kappa-type opioid receptor isoform 1	0	1	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
Beta-galactosidase	0	0	1	1
Histidine decarboxylase	0	0	1	1
Kappa-type opioid receptor	0	2	1	3
Nociceptin receptor	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
polyadenylate-binding protein 1	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	2	1	3
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	1	2
Substance-P receptor	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
Alpha-synuclein	1	1	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Amine oxidase [flavin-containing] B	0	3	0	3
Membrane primary amine oxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
DNA polymerase III, partial	1	0	0	1
XBP1	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	2	0	3
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	2	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
pyruvate kinase	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Dihydrofolate reductase	0	3	0	3
Ornithine decarboxylase	1	0	0	1
Pteridine reductase 1	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Transcriptional activator protein LuxR	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (230)

Protein Targets (935)

Trichotillomania

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (230)

Drugs Studied (99)

Protein Targets (935)