Cerebral Cortical Dysplasia

Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.

Synonym
Cortical Dysplasia, Cerebral
Malformations of Cortical Development
Cortical Dysplasia
Malformations of Cerebral Cortex Development
Cerebral Cortical Dysplasia

Excerpt	Reference
"Focal malformations of cortical development are highly associated with intractable epilepsy in children and adults."	( Crino, PB, 2009)
"Cortical dysplasia is a cortical malformation resulting from any developmental defects during different periods of development."	( Ateş, U; Baka, M; Kültürsay, N; Uyanikgil, Y, 2010)
"Focal cortical dysplasia is associated with the development of seizures in children and is present in up to 40% of intractable childhood epilepsies."	( Albertson, AJ; Hablitz, JJ; Yang, J, 2011)
"Malformations of cortical development are disturbances in brain formation that arise from abnormalities affecting the processes of cortical development."	( Bartha, R; Burneo, JG; Diosy, D; Nikolova, S; Parrent, AG; Steven, DA, 2015)
"Cortical dysplasia is the most common etiology of intractable epilepsy."	( Feng, L; Wang, YL; Xiao, B; Yue, ZW, 2018)
"Cortical dysplasias are alterations in the organization of the layers of the brain cortex due to problems in neuronal migration during development."	( Licea-Rodríguez, J; Luna-Palacios, Y; Martínez-Mendoza, ML; Martínez-Torres, A; Rocha-Mendoza, I; Rodríguez-Arzate, CA, 2021)

Excerpt	Reference
"Patients with cortical dysplasia (CD) are difficult to treat because the MRI abnormality may be undetectable."	( Engel, J; Fried, I; Koh, S; Koo, J; Kung, J; Lerner, JT; Mathern, GW; Miyata, H; Salamon, N; Sankar, R; Shaw, SJ; Shields, WD; Vinters, HV; Wu, JY; Yong, WH, 2008)
"The experimental model of cortical dysplasia (CD) obtained by administering carmustine (1-3-bis-chloroethyl-nitrosurea [BCNU]) in pregnant rat uterus mimics the histopathological abnormalities observed in human CD patients: altered cortical layering, and presence of heterotopia and dysmorphic/heterotopic neurons."	( Frassoni, C; Inverardi, F; Moroni, RF; Regondi, MC; Spreafico, R; Watakabe, A; Yamamori, T, 2009)
"It has been concluded that cortical dysplasia induced by intrauterine BCNU administration results in delayed hippocampal maturation, which is successfully restored by intrauterine melatonin treatment."	( Ateş, U; Baka, M; Kültürsay, N; Uyanikgil, Y, 2010)
"Patients with hemispheric malformations of cortical development (such as polymicrogyria) often develop medically intractable epilepsies for which hemispherotomy can be an excellent treatment option."	( Kudernatsch, M; Pieper, T; Staudt, M; Zsoter, A, 2012)
"We developed a model of cortical dysplasia in ferrets involving administration of methylaxozymethanol acetate (MAM), an antimitotic, to pregnant ferrets on gestational day 33, leading to dramatic reduction of layer 4 in the neocortex."	( Abbah, J; Juliano, SL, 2014)
"Focal cortical dysplasia (FCD) is associated with blood-brain barrier (BBB) dysfunction in patients with difficult-to-treat epilepsy."	( Ghosh, C; Hossain, M; Liu, X; Myers, R; Najm, IM; Nemeth, M; O'Connor, C; Williams, S, 2022)
"Focal cortical dysplasia (FCD) represents an essential cause of drug-resistant epilepsy with surgery as an effective treatment option."	( Hu, WH; Sang, L; Shao, XQ; Wan, HJ; Wang, SS; Wang, X; Zhang, C; Zhang, JG; Zhang, K; Zheng, Z; Zhou, F, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	43 (23.76)	18.1394
2010's	108 (59.67)	28.8240
2020's	30 (16.57)	9.53

Drug	Relationship Strength	Studies
gamma-aminobutyric acid	low	15
aminolevulinic acid	low	1
adenine	low	1
choline	low	2
chlorine	low	2
salicylic acid	low	7
creatine	low	2
lactic acid	low	1
hydrogen carbonate	low	1
hydrogen	low	1
inositol	low	1
melatonin	low	3
urea	low	1
2-amino-5-phosphonovalerate	low	2
ibotenic acid	low	3
pk 11195	low	1
4-aminopyridine	low	1
bumetanide	low	1
carbamazepine	low	6
carmustine	low	12
citalopram	low	1
clonazepam	low	1
diazepam	low	1
valproic acid	low	2
flumazenil	low	2
gabapentin	low	1
lamotrigine	low	2
metformin	low	1
nifedipine	low	1
phenobarbital	low	1
piracetam	low	5
thalidomide	low	1
vigabatrin	low	3
prednisolone	low	1
thyroxine	low	1
pilocarpine	low	6
pentylenetetrazole	low	6
aspartic acid	low	3
bromodeoxyuridine	low	1
methionine	low	1
valine	low	1
tryptophan	low	1
quinoxalines	low	1
flurothyl	low	2
bicuculline	low	2
kainic acid	low	2
methamphetamine	low	1
malondialdehyde	low	1
glycerylphosphorylcholine	low	1
ethylnitrosourea	low	2
vancomycin	low	1
fluorescein	low	2
n-methylaspartate	low	2
manganese	low	1
gadolinium	low	1
carbamide peroxide	low	1
glutamic acid	low	9
oxcarbazepine	low	1
substance p	low	2
propiconazole	low	1
delphinidin	low	1
fluorodeoxyglucose f18	low	22
dihydrokainate	low	1
luzindole	low	1
zd 7288	low	1
substance p (5-11)	low	1
biotin	low	1
lacosamide	low	1
fumaric acid	low	1
keratan sulfate	low	1
propylthiouracil	low	2
alpha-methyltryptophan, (l)-isomer	low	1
D-fructopyranose	low	2
tamoxifen	low	1
freedom	low	1
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline	low	1
myelin basic protein	low	3
4-hydroxy-2-nonenal	low	1
levetiracetam	low	5
sirolimus	low	15
topiramate	low	3
dexmedetomidine	low	1
methylazoxymethanol acetate	low	11
fumarates	low	1
cysteine	low	1
phosphorus	low	2
carbocyanines	low	2
tetrodotoxin	low	1
methylazoxymethanol	low	7
everolimus	low	3
phosphocreatine	low	2
perampanel	low	1
ro 16-0154	low	1
acid phosphatase	low	1
nad	low	1
quetiapine fumarate	low	2
vasoactive intestinal peptide	low	1
transforming growth factor beta	low	1
glutaminase	low	1
cyclin d1	low	1
technetium tc 99m bicisate	low	1

Protein Targets (1,183)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	16	0	0	16
euchromatic histone-lysine N-methyltransferase 2	33	0	0	33
Bloom syndrome protein isoform 1	19	0	0	19
peripheral myelin protein 22 isoform 1	7	0	0	7
D(1A) dopamine receptor	7	0	0	7
lamin isoform A-delta10	19	0	0	19
Glutamate receptor 1	0	9	2	13
Glutamate receptor ionotropic, NMDA 1	0	12	3	17
Glutamate receptor ionotropic, kainate 3	0	11	0	11
Glutamate receptor ionotropic, NMDA 2A	0	12	3	17
Glutamate receptor ionotropic, NMDA 2B	0	13	3	18
Glutamate receptor ionotropic, NMDA 2C	0	12	3	17
Glutamate receptor ionotropic, NMDA 2D	0	12	3	17
Glutamate receptor ionotropic, NMDA 3B	0	12	3	17
Glutamate receptor ionotropic, NMDA 3A	0	12	3	17
ATP-dependent phosphofructokinase	16	0	0	16
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	8	0	0	8
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
15-lipoxygenase, partial	1	0	0	1
phosphopantetheinyl transferase	14	0	0	14
USP1 protein, partial	12	0	0	12
Microtubule-associated protein tau	10	0	0	10
alpha-galactosidase	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
vitamin D3 receptor isoform VDRA	8	0	0	8
thyroid hormone receptor beta isoform a	8	0	0	8
DNA polymerase kappa isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	9	0	0	9
Metabotropic glutamate receptor 6	0	2	3	6
Glutamate receptor 2	8	8	2	20
Glutamate receptor 3	0	8	2	12
Glutamate receptor 4	0	8	2	12
Glutamate receptor ionotropic, kainate 1	0	9	3	12
Adenosine receptor A1	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	5	2	7
Glutamate receptor ionotropic, kainate 2	0	9	3	12
Glutamate receptor 1	0	7	2	10
Glutamate receptor 2	0	6	2	9
Glutamate receptor 3	0	4	2	6
Glutamate receptor 4	0	6	1	8
D(2) dopamine receptor	0	2	1	3
Glutamate receptor ionotropic, kainate 4	0	8	0	8
Glutamate receptor ionotropic, kainate 2	0	5	2	7
Glutamate receptor ionotropic, kainate 3	0	5	0	5
Glutamate receptor ionotropic, kainate 5	0	8	1	9
Chain A, Cruzipain	1	0	0	1
thioredoxin reductase	19	0	0	19
RAR-related orphan receptor gamma	15	0	0	15
aldehyde dehydrogenase 1 family, member A1	18	0	0	18
thyroid stimulating hormone receptor	15	0	0	15
estrogen receptor 2 (ER beta)	7	0	0	7
cytochrome P450 family 3 subfamily A polypeptide 4	11	0	0	11
glucocorticoid receptor [Homo sapiens]	18	0	0	18
cytochrome P450 2D6	6	0	0	6
glucocerebrosidase	2	0	0	2
IDH1	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	6	0	0	6
cytochrome P450 2D6 isoform 1	7	0	0	7
chromobox protein homolog 1	17	0	0	17
transcriptional regulator ERG isoform 3	3	0	0	3
thyroid hormone receptor beta isoform 2	14	0	0	14
mitogen-activated protein kinase 1	4	0	0	4
geminin	26	0	0	26
peripheral myelin protein 22	7	0	0	7
survival motor neuron protein isoform d	7	0	0	7
lethal factor (plasmid)	5	0	0	5
Potassium channel subfamily K member 2	0	0	2	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
Cellular tumor antigen p53	16	0	0	16
Potassium voltage-gated channel subfamily A member 3	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	11	0	11
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	23	0	0	23
AR protein	19	0	0	19
nuclear receptor subfamily 1, group I, member 3	14	0	0	14
estrogen-related nuclear receptor alpha	19	0	0	19
pregnane X nuclear receptor	16	0	0	16
estrogen nuclear receptor alpha	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
heat shock protein beta-1	4	0	0	4
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Bile salt export pump	0	28	0	28
Cyclin-dependent kinase 1	0	1	2	3
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	6	0	0	6
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	9	0	0	9
Ataxin-2	10	0	0	10
Chain A, Beta-lactamase	8	0	0	8
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
Gamma-aminobutyric acid receptor subunit rho-1	0	1	2	3
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Chain A, Ferritin light chain	9	0	0	9
arylsulfatase A	12	0	0	12
cytochrome P450 2C19 precursor	8	0	0	8
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	8	0	14
Carbonic anhydrase 2	0	8	1	15
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Excitatory amino acid transporter 1	0	4	0	5
Excitatory amino acid transporter 2	0	4	0	5
Excitatory amino acid transporter 3	0	4	0	5
Metabotropic glutamate receptor 1	0	2	2	5
Metabotropic glutamate receptor 2	0	2	3	6
Carbonic anhydrase-like protein, putative	0	0	0	3
Carbonic anhydrase 4	0	2	0	3
Gamma-aminobutyric acid receptor subunit pi	0	7	0	7
Gamma-aminobutyric acid receptor subunit delta	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	7	4	11
Gamma-aminobutyric acid receptor subunit beta-1	0	7	1	8
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit beta-3	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-5	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-3	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-2	0	7	2	9
Gamma-aminobutyric acid receptor subunit beta-2	0	7	2	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	1	8
Gamma-aminobutyric acid receptor subunit epsilon	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	0	7	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	0	7	0	7
Gamma-aminobutyric acid receptor subunit theta	0	7	0	7
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
apical membrane antigen 1, AMA1	3	0	0	3
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
interleukin 8	4	0	0	4
pregnane X receptor	5	0	0	5
ATAD5 protein, partial	9	0	0	9
progesterone receptor	9	0	0	9
retinoic acid nuclear receptor alpha variant 1	14	0	0	14
retinoid X nuclear receptor alpha	11	0	0	11
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
cellular tumor antigen p53 isoform a	5	0	0	5
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
oxysterols receptor LXR-beta isoform 1	0	0	1	1
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
muscarinic acetylcholine receptor M1	9	0	0	9
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Nuclear receptor ROR-gamma	4	0	0	4
Spike glycoprotein	7	0	1	8
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
Luciferase	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
muscleblind-like protein 1 isoform 1	3	0	0	3
neuropeptide S receptor isoform A	3	0	0	3
ATP-binding cassette sub-family C member 3	0	19	0	19
Multidrug resistance-associated protein 4	0	19	0	19
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	4	0	7
Carbonic anhydrase 3	0	4	0	5
Carbonic anhydrase 4	0	6	0	9
Carbonic anhydrase 6	0	4	0	7
Carbonic anhydrase 5A, mitochondrial	0	4	1	9
Carbonic anhydrase 7	0	4	0	7
Solute carrier family 12 member 2	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Carbonic anhydrase 9	0	4	0	7
Carbonic anhydrase 13	0	3	0	6
Carbonic anhydrase 14	0	4	0	7
Carbonic anhydrase 5B, mitochondrial	0	4	0	8
acetylcholinesterase	5	0	0	5
Vpr	1	0	0	1
Bile salt export pump	0	6	0	6
Albumin	0	0	2	2
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
Cytochrome P450 2C9	0	4	0	4
UDP-glucuronosyltransferase 2B7	0	1	0	3
Cytochrome P450 2B6	0	1	1	2
Sodium channel protein type 4 subunit alpha	0	3	0	5
Cytochrome P450 2J2	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	6	0	6
Frizzled-8	0	0	1	1
Canalicular multispecific organic anion transporter 1	0	17	0	17
P2X purinoceptor 4	0	2	0	2
GLI family zinc finger 3	13	0	0	13
endonuclease IV	5	0	0	5
EWS/FLI fusion protein	12	0	0	12
peroxisome proliferator activated receptor gamma	14	0	0	14
huntingtin isoform 2	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	13	0	0	13
nuclear receptor ROR-gamma isoform 1	8	0	0	8
Glutathione reductase, mitochondrial	0	5	0	5
Alpha-synuclein	4	1	0	5
Glutathione reductase	0	1	0	1
Carbonic anhydrase	0	3	0	4
Carbonic anhydrase 15	0	5	0	6
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	4	0	4
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	4	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	4	0	4
Solute carrier family 22 member 1	0	1	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	6	0	6
Aldo-keto reductase family 1 member B1	0	5	0	5
Tryptophan 5-hydroxylase 1	0	1	0	1
Angiotensin-converting enzyme	0	4	0	4
Aldo-keto reductase family 1 member B1	0	1	0	1
5-hydroxytryptamine receptor 1A	0	6	2	8
Aromatase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	4	1	5
Sodium-dependent dopamine transporter	0	1	0	1
Alpha-1D adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 2C	0	6	0	6
Sodium-dependent serotonin transporter	0	4	2	6
Sodium-dependent serotonin transporter	0	2	0	2
Histamine H1 receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	4	0	4
5-hydroxytryptamine receptor 7	0	1	0	1
Sodium-dependent dopamine transporter	0	3	0	3
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	2	0	2
Transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	7	9	2	18
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	7	9	2	18
Gamma-aminobutyric acid receptor subunit delta	7	9	2	18
Gamma-aminobutyric acid receptor subunit gamma-2	7	9	3	19
Gamma-aminobutyric acid receptor subunit alpha-5	7	9	2	18
Gamma-aminobutyric acid receptor subunit alpha-3	7	9	2	18
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-1	7	9	2	18
Gamma-aminobutyric acid receptor subunit alpha-2	7	9	2	18
Gamma-aminobutyric acid receptor subunit alpha-4	7	9	2	18
Gamma-aminobutyric acid receptor subunit gamma-3	7	9	2	18
Gamma-aminobutyric acid receptor subunit alpha-6	7	9	2	18
Translocator protein	0	2	0	2
Translocator protein	0	4	1	6
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	7	9	3	19
Gamma-aminobutyric acid receptor subunit beta-3	7	9	2	18
Gamma-aminobutyric acid receptor subunit beta-2	7	9	3	19
GABA theta subunit	7	9	2	18
Gamma-aminobutyric acid receptor subunit epsilon	7	9	2	18
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Epidermal growth factor receptor	0	2	2	4
Vascular endothelial growth factor receptor 2	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2C9 precursor	4	0	0	4
cytochrome P450 3A4 isoform 1	7	0	0	7
Alpha-2A adrenergic receptor	0	4	1	5
Alpha-1B adrenergic receptor	0	6	0	6
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-2C adrenergic receptor	0	1	1	2
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	7	0	7
Histamine H2 receptor	6	0	0	6
Gamma-aminobutyric acid	0	1	1	2
glp-1 receptor, partial	3	0	0	3
G	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Interferon beta	7	0	0	7
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
Fatty acid-binding protein, liver	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	1	2	4
ATP-dependent translocase ABCB1	0	4	1	6
Translocator protein	0	3	2	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Inositol hexakisphosphate kinase 1	5	0	0	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
cytochrome P450 2C9, partial	5	0	0	5
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	2	0	2
Chain A, Glutamate Receptor Subunit 2	0	2	0	2
Chain B, Glutamate Receptor Subunit 2	0	2	0	2
Chain A, Glutamate receptor 2	0	1	0	1
Chain A, Glutamate receptor 2	0	1	0	1
Chain A, Glutamate receptor	0	1	0	1
activating transcription factor 6	3	0	0	3
Bone morphogenetic protein receptor type-1B	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	1	2	3
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	0	2	2
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	1	2	3
Insulin receptor	0	0	2	2
Tyrosine-protein kinase Lck	0	1	2	3
Tyrosine-protein kinase Fyn	0	1	2	3
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	0	2	2
Platelet-derived growth factor receptor beta	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	2	2
Serine/threonine-protein kinase pim-1	0	0	2	2
Fibroblast growth factor receptor 1	0	0	2	2
DNA topoisomerase 2-alpha	0	0	2	2
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	3	0	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	2	4
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Cyclin-dependent kinase 2	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	2	2
Mitogen-activated protein kinase 1	0	0	2	2
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	1	2	3
Exosome RNA helicase MTR4	0	0	2	2
Serine/threonine-protein kinase mTOR	0	2	2	4
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Potassium voltage-gated channel subfamily KQT member 1	0	3	0	3
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	3
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	0	2	2
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	1	2	3
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Sodium channel protein type 5 subunit alpha	0	4	0	4
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	1	2	3
Mitogen-activated protein kinase 11	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Mitogen-activated protein kinase 14	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Regulatory-associated protein of mTOR	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Aurora kinase B	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	3
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
regulator of G-protein signaling 4	11	0	0	11
flap endonuclease 1	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
SMAD family member 2	3	0	0	3
SMAD family member 3	3	0	0	3
farnesoid X nuclear receptor	8	0	0	8
peroxisome proliferator-activated receptor delta	7	0	0	7
aryl hydrocarbon receptor	9	0	0	9
thyrotropin-releasing hormone receptor	2	0	0	2
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
Lysine-specific demethylase 4E	0	1	0	1
NADP-dependent malic enzyme, mitochondrial	0	0	0	1
Solute carrier family 22 member 20	0	2	0	2
Prolyl 4-hydroxylase	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Egl nine homolog 1	0	1	1	2
Methyl-accepting chemotaxis protein NahY	0	0	1	1
thioredoxin glutathione reductase	2	0	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
Histone deacetylase 3	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
Histone deacetylase 1	0	3	0	3
Sterol O-acyltransferase 1	0	0	1	1
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	3	0	3
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Histone deacetylase 6	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	1	2
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
GLS protein	8	0	0	8
beta-2 adrenergic receptor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
Metabotropic glutamate receptor 8	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Integrin beta-3	3	0	1	4
Integrin alpha-IIb	3	0	1	4
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 1	0	2	2	4
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Metabotropic glutamate receptor 5	0	2	2	5
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	2	2	5
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	3	0	3
Glutamate racemase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
dopamine D1 receptor	1	0	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
DNA polymerase iota isoform a (long)	7	0	0	7
Amyloid-beta precursor protein	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
thyroid stimulating hormone receptor	5	0	0	5
GALC protein	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
Dihydrofolate reductase	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	2	0	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Synaptic vesicle glycoprotein 2A	0	2	0	2
Melatonin receptor type 1A	0	3	1	4
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	3	1	4
ClpP	1	0	0	1
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
ras-related protein Rab-9A	2	0	0	2
M-phase phosphoprotein 8	5	0	0	5
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	3	0	3
Cytochrome P450 1A2	0	2	0	2
Cholinesterase	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Cytochrome P450 2D6	0	1	0	1
Aromatase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Cytochrome P450 1B1	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Fumarate hydratase	3	0	0	3
NFKB1 protein, partial	1	0	0	1
Thrombopoietin	1	0	0	1
Smad3	3	0	0	3
hypothetical protein, conserved	1	0	0	1
nonstructural protein 1	3	0	0	3
polyprotein	3	0	0	3
67.9K protein	4	0	0	4
Parkin	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
tumor necrosis factor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
eyes absent homolog 2 isoform a	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Muscarinic acetylcholine receptor M2	0	3	1	5
Muscarinic acetylcholine receptor M4	0	2	0	3
Cytochrome P450 3A4	0	6	0	6
Muscarinic acetylcholine receptor M5	0	3	0	4
Adenosine receptor A3	0	4	0	4
Muscarinic acetylcholine receptor M1	0	3	2	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Thromboxane-A synthase	0	2	0	2
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Adenosine receptor A2a	0	3	0	3
Adenosine receptor A1	0	4	0	4
Adenosine receptor A2a	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
C-C chemokine receptor type 2	0	2	0	2
Inositol monophosphatase 1	1	0	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Leukotriene B4 receptor 1	0	0	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Beta-2 adrenergic receptor	0	0	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Replicase polyprotein 1ab	0	1	1	2
Muscarinic acetylcholine receptor M1	0	2	0	3
Muscarinic acetylcholine receptor M3	0	2	0	3
Muscarinic acetylcholine receptor M4	0	2	0	3
Muscarinic acetylcholine receptor M5	0	2	0	3
Muscarinic acetylcholine receptor M2	0	2	0	3
Cytochrome P450 2A6	0	2	1	3
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
Guanine nucleotide-binding protein G	2	0	0	2
prostaglandin E2 receptor EP2 subtype	0	0	0	1
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	4	1	6
Glucocorticoid receptor	0	2	1	8
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	3	0	3
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Histamine H1 receptor	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Cytochrome P450 2C19	0	2	0	2
Serine/threonine-protein kinase receptor R3	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C zeta type	0	1	1	2
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Solute carrier organic anion transporter family member 1B1	0	1	0	2
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	4	0	4
Substance-P receptor	0	4	1	5
Neuromedin-K receptor	0	1	1	2
Substance-P receptor	0	2	0	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Chain A, CES1 protein	0	1	0	1
PPM1D protein	1	0	0	1
DNA polymerase III, partial	1	0	0	1
Histone H2A.x	2	0	0	2
Caspase-7	1	0	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
interferon gamma precursor	0	0	0	1
caspase-3	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
streptokinase A precursor	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	2
Procathepsin L	0	0	1	1
Beta-1 adrenergic receptor	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Protein kinase C eta type	0	1	0	1
Histamine H2 receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Melanocortin receptor 3	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
5-hydroxytryptamine receptor 6	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Cereblon isoform 4	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
DNA polymerase eta isoform 1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Cytochrome P450 2C8	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	2
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Chain A, Arginase 1	0	1	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Cerebral Cortical Dysplasia

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (181)

Protein Targets (1,183)

Cerebral Cortical Dysplasia

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (181)

Drugs Studied (114)

Protein Targets (1,183)