Page last updated: 2024-10-26

valproic acid and Cerebral Cortical Dysplasia

valproic acid has been researched along with Cerebral Cortical Dysplasia in 2 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Valproic acid treated animals were treated from 5 days preceding behavioral testing in the Morris water maze at a clinically relevant concentration."5.42Standard dose valproic acid does not cause additional cognitive impact in a rodent model of intractable epilepsy. ( Jellett, AP; Jenks, K; Lucas, M; Scott, RC, 2015)
"Valproic acid treated animals were treated from 5 days preceding behavioral testing in the Morris water maze at a clinically relevant concentration."1.42Standard dose valproic acid does not cause additional cognitive impact in a rodent model of intractable epilepsy. ( Jellett, AP; Jenks, K; Lucas, M; Scott, RC, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jellett, AP1
Jenks, K1
Lucas, M1
Scott, RC1
Arora, M1
Praharaj, SK1
Sinha, VK1
Sarkar, S1

Other Studies

2 other studies available for valproic acid and Cerebral Cortical Dysplasia

ArticleYear
Standard dose valproic acid does not cause additional cognitive impact in a rodent model of intractable epilepsy.
    Epilepsy research, 2015, Volume: 110

    Topics: Animals; Animals, Newborn; Anticonvulsants; Cognition; Cognition Disorders; Disease Models, Animal;

2015
Schizencephaly associated with bipolar II disorder.
    Singapore medical journal, 2009, Volume: 50, Issue:2

    Topics: Bipolar Disorder; Brain; Citalopram; Depression; Diagnosis, Differential; Dibenzothiazepines; Humans

2009