carmustine has been researched along with Cerebral Cortical Dysplasia in 12 studies
Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
carmustine : A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Focal cortical dysplasias (FCDs) are malformations of cortical development that often result in medically refractory epilepsy, with a greater incidence in the pediatric population." | 1.91 | Altered functional connectivity and network excitability in a model of cortical dysplasia. ( Aquiles, A; Concha, L; Fiordelisio, T; Luna-Munguia, H, 2023) |
| "Carmustine-treated mice were affected in their motor coordination and balance." | 1.62 | Morphological and Calcium Signaling Alterations of Neuroglial Cells in Cerebellar Cortical Dysplasia Induced by Carmustine. ( Licea-Rodríguez, J; Luna-Palacios, Y; Martínez-Mendoza, ML; Martínez-Torres, A; Rocha-Mendoza, I; Rodríguez-Arzate, CA, 2021) |
| "It has been concluded that cortical dysplasia induced by intrauterine BCNU administration results in delayed hippocampal maturation, which is successfully restored by intrauterine melatonin treatment." | 1.36 | Investigation of maternal melatonin effect on the hippocampal formation of newborn rat model of intrauterine cortical dysplasia. ( Ateş, U; Baka, M; Kültürsay, N; Uyanikgil, Y, 2010) |
| "The experimental model of cortical dysplasia (CD) obtained by administering carmustine (1-3-bis-chloroethyl-nitrosurea [BCNU]) in pregnant rat uterus mimics the histopathological abnormalities observed in human CD patients: altered cortical layering, and presence of heterotopia and dysmorphic/heterotopic neurons." | 1.35 | Expression of layer-specific markers in the adult neocortex of BCNU-Treated rat, a model of cortical dysplasia. ( Frassoni, C; Inverardi, F; Moroni, RF; Regondi, MC; Spreafico, R; Watakabe, A; Yamamori, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Aquiles, A | 1 |
| Fiordelisio, T | 1 |
| Luna-Munguia, H | 1 |
| Concha, L | 1 |
| Rodríguez-Arzate, CA | 1 |
| Martínez-Mendoza, ML | 1 |
| Rocha-Mendoza, I | 1 |
| Luna-Palacios, Y | 1 |
| Licea-Rodríguez, J | 1 |
| Martínez-Torres, A | 2 |
| Moroni, RF | 7 |
| Inverardi, F | 7 |
| Regondi, MC | 7 |
| Pennacchio, P | 3 |
| Spreafico, R | 5 |
| Frassoni, C | 7 |
| González-González, MA | 1 |
| Ostos-Valverde, A | 1 |
| Becerra-Hernández, A | 1 |
| Sánchez-Castillo, H | 1 |
| Noé, F | 1 |
| Gnatkovsky, V | 1 |
| Zucca, I | 3 |
| de Curtis, M | 1 |
| Watakabe, A | 1 |
| Yamamori, T | 1 |
| Baka, M | 1 |
| Uyanikgil, Y | 1 |
| Ateş, U | 1 |
| Kültürsay, N | 1 |
| Cipelletti, B | 1 |
| Mastropietro, A | 1 |
| Chikhladze, M | 1 |
| Donzelli, A | 1 |
| Corradini, I | 1 |
| Braida, D | 1 |
| Sala, M | 1 |
| Franceschetti, S | 1 |
| Long, LL | 1 |
| Xiao, B | 1 |
| Song, YM | 1 |
| Wang, K | 1 |
| Panzica, F | 1 |
12 other studies available for carmustine and Cerebral Cortical Dysplasia
| Article | Year |
|---|---|
Altered functional connectivity and network excitability in a model of cortical dysplasia.
Topics: Animals; Calcium; Carmustine; Child; Humans; Malformations of Cortical Development; Neurons; Pilocar | 2023 |
Morphological and Calcium Signaling Alterations of Neuroglial Cells in Cerebellar Cortical Dysplasia Induced by Carmustine.
Topics: Animals; Astrocytes; Calcium Signaling; Carmustine; Cells, Cultured; Cerebellum; Malformations of Co | 2021 |
Genesis of heterotopia in BCNU model of cortical dysplasia, detected by means of in utero electroporation.
Topics: Animals; Axons; Carmustine; Cell Differentiation; Cell Movement; Disease Models, Animal; Electropora | 2013 |
The effect of carmustine on Bergmann cells of the cerebellum.
Topics: Alkylating Agents; Animals; Carmustine; Cerebellum; Female; Malformations of Cortical Development; M | 2015 |
Increased pCREB expression and the spontaneous epileptiform activity in a BCNU-treated rat model of cortical dysplasia.
Topics: Age Factors; Animals; Antineoplastic Agents, Alkylating; Brain; Calbindins; Carmustine; CREB-Binding | 2015 |
Expression of layer-specific markers in the adult neocortex of BCNU-Treated rat, a model of cortical dysplasia.
Topics: Animals; Carmustine; Disease Models, Animal; DNA-Binding Proteins; Female; Gene Expression Regulatio | 2009 |
Investigation of maternal melatonin effect on the hippocampal formation of newborn rat model of intrauterine cortical dysplasia.
Topics: Animals; Animals, Newborn; Antineoplastic Agents, Alkylating; Carmustine; Female; Glial Fibrillary A | 2010 |
Development of cortical malformations in BCNU-treated rat, model of cortical dysplasia.
Topics: Animals; Animals, Newborn; Carmustine; Cell Differentiation; Cell Movement; Disease Models, Animal; | 2011 |
In vivo detection of cortical abnormalities in BCNU-treated rats, model of cortical dysplasia, using manganese-enhanced magnetic resonance imaging.
Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Disease Models, Animal; Image Enhancement; I | 2011 |
Cytoarchitectural, behavioural and neurophysiological dysfunctions in the BCNU-treated rat model of cortical dysplasia.
Topics: Animals; Carmustine; Cognition; Disease Models, Animal; Entorhinal Cortex; Excitatory Postsynaptic P | 2013 |
[Changes of expression of cation-chloride cotransporter genes in hippocampus of cortical dysplasia: experiment with rat].
Topics: Animals; Animals, Newborn; Carmustine; Chlorides; Female; Gene Expression; Hippocampus; Ion Transpor | 2007 |
Altered spatial distribution of PV-cortical cells and dysmorphic neurons in the somatosensory cortex of BCNU-treated rat model of cortical dysplasia.
Topics: Animals; Animals, Newborn; Antibodies; Calbindins; Carmustine; Classical Lissencephalies and Subcort | 2008 |