pilocarpine has been researched along with Cerebral Cortical Dysplasia in 6 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thereafter, pilocarpine was administered, and significant differences in susceptibility to seizures were detected depending on the degree of brain dysplasia." | 7.96 | Changes of EEG spectra in rat brains with different patterns of dysplasia in response to pilocarpine-induced seizures. ( Gzieło, K; Janeczko, K; Kiełbinski, M; Setkowicz, Z; Węglarz, W, 2020) |
| " Thereafter, pilocarpine was administered, and significant differences in susceptibility to seizures were detected depending on the degree of brain dysplasia." | 3.96 | Changes of EEG spectra in rat brains with different patterns of dysplasia in response to pilocarpine-induced seizures. ( Gzieło, K; Janeczko, K; Kiełbinski, M; Setkowicz, Z; Węglarz, W, 2020) |
| " The analysis was performed in three conditions: naïve, during latent phase after pilocarpine-induced status epilepticus and after 21 days of transauricular electric shocks." | 3.88 | Profiles of gene expression in the hippocampal formation of rats with experimentally-induced brain dysplasia. ( Gzielo, K; Janeczko, K; Kielbinski, M; Setkowicz, Z, 2018) |
| " We induced cortical malformations by exposing rats prenatally to methylazoxymethanol acetate and triggered status epilepticus and recurrent seizures in adult methylazoxymethanol acetate rats with pilocarpine." | 3.77 | Status epilepticus-induced pathologic plasticity in a rat model of focal cortical dysplasia. ( Balosso, S; Battaglia, G; Carriero, G; Colciaghi, F; Finardi, A; Frasca, A; Locatelli, D; Nobili, P; Vezzani, A, 2011) |
| "Focal cortical dysplasias (FCDs) are malformations of cortical development that often result in medically refractory epilepsy, with a greater incidence in the pediatric population." | 1.91 | Altered functional connectivity and network excitability in a model of cortical dysplasia. ( Aquiles, A; Concha, L; Fiordelisio, T; Luna-Munguia, H, 2023) |
| "Cortical dysplasia is the most common etiology of intractable epilepsy." | 1.48 | Axon Initial Segment Structural Plasticity is Involved in Seizure Susceptibility in a Rat Model of Cortical Dysplasia. ( Feng, L; Wang, YL; Xiao, B; Yue, ZW, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Aquiles, A | 1 |
| Fiordelisio, T | 1 |
| Luna-Munguia, H | 1 |
| Concha, L | 1 |
| Setkowicz, Z | 2 |
| Kiełbinski, M | 1 |
| Gzieło, K | 1 |
| Węglarz, W | 1 |
| Janeczko, K | 2 |
| Yue, ZW | 1 |
| Wang, YL | 1 |
| Xiao, B | 2 |
| Feng, L | 2 |
| Kielbinski, M | 1 |
| Gzielo, K | 1 |
| Wang, Y | 1 |
| Sun, D | 1 |
| Yue, Z | 1 |
| Tang, W | 1 |
| Colciaghi, F | 1 |
| Finardi, A | 1 |
| Frasca, A | 1 |
| Balosso, S | 1 |
| Nobili, P | 1 |
| Carriero, G | 1 |
| Locatelli, D | 1 |
| Vezzani, A | 1 |
| Battaglia, G | 1 |
6 other studies available for pilocarpine and Cerebral Cortical Dysplasia
| Article | Year |
|---|---|
Altered functional connectivity and network excitability in a model of cortical dysplasia.
Topics: Animals; Calcium; Carmustine; Child; Humans; Malformations of Cortical Development; Neurons; Pilocar | 2023 |
Changes of EEG spectra in rat brains with different patterns of dysplasia in response to pilocarpine-induced seizures.
Topics: Animals; Brain; Electroencephalography; Female; Gamma Rays; Male; Malformations of Cortical Developm | 2020 |
Axon Initial Segment Structural Plasticity is Involved in Seizure Susceptibility in a Rat Model of Cortical Dysplasia.
Topics: Animals; Axon Initial Segment; Axons; Disease Models, Animal; Disease Susceptibility; Electroencepha | 2018 |
Profiles of gene expression in the hippocampal formation of rats with experimentally-induced brain dysplasia.
Topics: Animals; Electroshock; Hippocampus; Male; Malformations of Cortical Development; Microarray Analysis | 2018 |
Rats with Malformations of Cortical Development Exhibit Decreased Length of AIS and Hypersensitivity to Pilocarpine-Induced Status Epilepticus.
Topics: Animals; Axon Initial Segment; Disease Models, Animal; Female; Hypersensitivity; Malformations of Co | 2016 |
Status epilepticus-induced pathologic plasticity in a rat model of focal cortical dysplasia.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Malformations of Cortical Development; Methylazoxy | 2011 |