Page last updated: 2024-10-25

deferoxamine and Siderosis

deferoxamine has been researched along with Siderosis in 81 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Siderosis: A form of pneumoconiosis resulting from inhalation of iron in the mining dust or welding fumes.

Research Excerpts

ExcerptRelevanceReference
"Cardiac events and death are not uncommon in adults with beta-thalassemia (b-TM) taking deferoxamine (DFO) monotherapy because of poor compliance and possibly the less effectiveness of DFO in controlling cardiac iron overload."7.76Cardiac events and cardiac T2* in Egyptian children and young adults with beta-thalassemia major taking deferoxamine. ( Abdin, IA; Ebeid, FS; El Safy, UR; Elalfy, MS; Ibrahim, AS; Salem, DS, 2010)
"Deferiprone monotherapy was significantly more effective than deferoxamine over 1 year in improving asymptomatic myocardial siderosis in beta-thalassemia major."6.72Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis. ( Aessopos, A; Berdoukas, V; Galanello, R; Gotsis, ED; Karagiorga, M; Ladis, V; Pennell, DJ; Piga, A; Smith, GC; Tanner, MA; Westwood, MA; Wonke, B, 2006)
"In patients with severe myocardial siderosis and impaired LV function, combined chelation therapy with subcutaneous deferoxamine and oral deferiprone reduces myocardial iron and improves cardiac function."5.13Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction. ( Agus, A; Dessi, C; Galanello, R; Nair, SV; Pennell, DJ; Pibiri, M; Smith, GC; Tanner, MA; Walker, JM; Westwood, MA, 2008)
"Cardiac events and death are not uncommon in adults with beta-thalassemia (b-TM) taking deferoxamine (DFO) monotherapy because of poor compliance and possibly the less effectiveness of DFO in controlling cardiac iron overload."3.76Cardiac events and cardiac T2* in Egyptian children and young adults with beta-thalassemia major taking deferoxamine. ( Abdin, IA; Ebeid, FS; El Safy, UR; Elalfy, MS; Ibrahim, AS; Salem, DS, 2010)
"Deferiprone monotherapy was significantly more effective than deferoxamine over 1 year in improving asymptomatic myocardial siderosis in beta-thalassemia major."2.72Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis. ( Aessopos, A; Berdoukas, V; Galanello, R; Gotsis, ED; Karagiorga, M; Ladis, V; Pennell, DJ; Piga, A; Smith, GC; Tanner, MA; Westwood, MA; Wonke, B, 2006)
"In transfusion-dependent ss-thalassemia major, increased iron deposition in the pituitary gland has a cytotoxic effect, leading mainly to hypogonadotropic hypogonadism."1.31T2 relaxation rate as an index of pituitary iron overload in patients with beta-thalassemia major. ( Argyropoulou, MI; Bitsis, S; Efremidis, S; Kiortsis, DN; Metafratzi, Z; Tsatsoulis, A, 2000)
"A 32 year old woman with severe aplastic anaemia required frequent transfusions and consequently developed hyperferrioxaemia (54 microMol/l) and hyperferritinaemia (1,700 ng/ml)."1.27High dosage desferrioxamine therapy in a female patient with acquired aplastic anaemia and transfusion siderosis. ( Bleyl, H; Breithaupt, H; Graef, V; Guttmann, W; Heckers, H; Jundt, G; Pralle, H, 1986)

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199072 (88.89)18.7374
1990's3 (3.70)18.2507
2000's5 (6.17)29.6817
2010's1 (1.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peng, CT1
Chang, JS1
Wang, LY1
Chiou, SS1
Hsiao, CC1
Wang, SC1
Hung, GY1
Wu, KH1
Elalfy, MS1
Abdin, IA1
El Safy, UR1
Ibrahim, AS1
Ebeid, FS1
Salem, DS1
ALBAHARY, C3
RENAULT, J1
LABARBE, P1
GIRAUD, J1
NORMAN, CS1
REWALD, E1
SCURO, LA5
BROCCIA, G1
DOBRILLA, G5
TAGLIAMONTE, A1
CARVALHONETO, E1
CHAVANNE, H1
DEMILLIERE, B1
TURA, S1
RICCI-BITTI, ML1
LODI, L1
RISSEL, E1
Pennell, DJ2
Berdoukas, V1
Karagiorga, M1
Ladis, V1
Piga, A1
Aessopos, A1
Gotsis, ED1
Tanner, MA2
Smith, GC2
Westwood, MA2
Wonke, B1
Galanello, R2
Hershko, C2
Dessi, C1
Agus, A1
Pibiri, M1
Nair, SV1
Walker, JM1
Valvo, A2
Walsh, JR2
Mass, RE1
Williams, R1
Lechi, A1
Innecco, A1
Cavallini, G1
Green, R1
Lamon, J1
Curran, D1
Jacobs, A1
Ting, WC1
Piomelli, S1
Graziano, J1
Choi, YC1
Hough, AJ1
Morris, GM1
Sokoloff, L1
Ceriati, F1
Pomponi, M1
Cavicchioni, C1
Marino, IR1
Carelli, G1
Cremona, G1
Declercq, SS1
Krawczuk-Hermanowicz, O1
Smolińska, K1
Richardson, ME1
Matthews, RN1
Alison, JF1
Menahem, S1
Mitvalsky, J1
Byrt, E1
Harper, RW1
Lange, B1
Hofweber, K1
Waldherr, R1
Schärer, K1
Link, G1
Cabantchik, I1
Argyropoulou, MI1
Metafratzi, Z1
Kiortsis, DN1
Bitsis, S1
Tsatsoulis, A1
Efremidis, S1
Barcellona, R2
Masseria, R2
Palmigiano, C2
Amato, GM2
Kramer, P1
Arnold, H1
Wehinger, H1
Deus, B1
Löhr, GW1
Nienhuis, AW2
Strohmeyer, G1
Propper, RD1
Cooper, B1
Rufo, RR1
Anderson, WF1
Bunn, HF1
Rosenthal, A1
Nathan, DG1
Kautzsch, E1
Risdon, RA1
Barry, M2
Flynn, DM1
Peyresblanques, MJ1
Robins-Browne, RM1
Prpic, JK1
Stuart, SJ1
Gelmi, C1
Borgna-Pignatti, C1
Franchin, S1
Tacchini, M1
Trimarchi, F1
Gerkowicz, K2
Prost, M2
Breithaupt, H1
Heckers, H1
Pralle, H1
Guttmann, W1
Bleyl, H1
Graef, V1
Jundt, G1
Bobeck-Rutsaert, MM1
op den Kelder, AM1
Wiltink, WF1
van Eijk, HG1
Leijnse, B1
Stich, W1
Turbina, NS2
Khutsishvili, GE1
Soboleva, IuG1
Stacher, A1
Turnbull, A1
Michaelis, D1
Takác, A1
Bruns, W1
Asenjo, A1
Rojas, G1
Aranda, L1
Weinstein, V1
Oberhauser, E1
Wöhler, F1
Fiaschi, E1
Bianco, G1
Gallo, E1
Ramello, A1
Ricco, G1
Matone, S1
Wapnick, AA1
Lynch, SR1
Charlton, RW1
Seftel, HC1
Bothwell, TH1
Cartei, G1
Sherlock, S1
Campana, G1
Boschi, MC1
Lobitz, WC1
Mahler, DJ1
Kingery, FA1
Fielding, J1
Duverne, J1
Brizard, CP1
Mounier, R1
Pecora, L1
Cascini, F1
De Siena, F1
Bessière, E1
Verin, P1
Le Rebeller, MJ1
Descamp, F1
Beurey, J1
Weber, M1
Gurecki, H1
Perello, R1
Vadot, J1
Luongo, E1
el-Gholmy, A1
Khalifa, AS1
Rahman, YA1
el-Bagoury, I1
Lange, J1
Orsini, A1
Giraud, F1
Bernard, P1
Passeron, P1
Del Duca, A1
Scandellari, C1
Plachecka-Gutowska, M1
Mikolajew, M1
McEnery, JT1
Greengard, J1
Wise, JB1
Falbe-Hansen, I1
Aron, E2
Weill, JD2
Jobard, P1
Galand, A2
Domenech, J1
Paufique, L1
Bonnet, M1
Didierlaurent, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo Controlled, Double Blind Trial of the Effect of Combined Therapy With Deferoxamine and Deferiprone on Myocardial Iron in Thalassemia Major Using Cardiovascular Magnetic Resonance[NCT00103753]Phase 465 participants Interventional2004-05-31Active, not recruiting
The Effect of Treatment With the Oral Iron Chelator Deferiprone on the Oxidative Stress of Blood Cells and on Iron Overload Status in Transfusion Dependent, Iron-overloaded Patients With Low Risk Myelodysplastic Syndrome[NCT02477631]Phase 219 participants (Actual)Interventional2016-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for deferoxamine and Siderosis

ArticleYear
Pathophysiology of iron overload.
    Annals of the New York Academy of Sciences, 1998, Jun-30, Volume: 850

    Topics: Animals; Cardiomyopathies; Deferoxamine; Free Radicals; Humans; Iron; Siderosis; Thalassemia; Transf

1998
Yersiniae and iron. A study in host-parasite relationships.
    Contributions to microbiology and immunology, 1987, Volume: 9

    Topics: Deferoxamine; Humans; Iron; Siderosis; Virulence; Yersinia; Yersinia Infections

1987
[Use of desferal in treatment of sideroses of different origin. (Literature review)].
    Problemy gematologii i perelivaniia krovi, 1968, Volume: 13, Issue:7

    Topics: Anemia; Anemia, Aplastic; Anemia, Sideroblastic; Animals; Bile; Child, Preschool; Deferoxamine; Hemo

1968
[Diseases caused by iron metabolism disorders and their therapy].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1969, Volume: 50, Issue:3

    Topics: Adult; Anemia, Hypochromic; Anti-Glomerular Basement Membrane Disease; Bloodletting; Deferoxamine; D

1969
Iron metabolism in the porphyrias.
    The British journal of dermatology, 1971, Volume: 84, Issue:4

    Topics: Alcohol Drinking; Amino Acids; Anemia, Hemolytic; Bloodletting; Bone Marrow; Bone Marrow Diseases; D

1971
[Recent findings on the subject of diagnosis of hypersiderosis].
    Minerva medica, 1967, Mar-24, Volume: 58, Issue:24

    Topics: Deferoxamine; Humans; Iron; Siderosis

1967

Trials

3 trials available for deferoxamine and Siderosis

ArticleYear
Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis.
    Blood, 2006, May-01, Volume: 107, Issue:9

    Topics: Adult; beta-Thalassemia; Cardiomyopathies; Deferiprone; Deferoxamine; Female; Humans; Iron; Iron Che

2006
Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2008, Feb-25, Volume: 10

    Topics: Administration, Oral; Adult; beta-Thalassemia; Cardiomyopathies; Deferiprone; Deferoxamine; Drug The

2008
Clinical trial of desferrioxamine entrapped in red cell ghosts.
    Lancet (London, England), 1980, Aug-16, Volume: 2, Issue:8190

    Topics: Adult; Aged; Anemia; Anemia, Aplastic; Blood Transfusion; Clinical Trials as Topic; Deferoxamine; Er

1980

Other Studies

72 other studies available for deferoxamine and Siderosis

ArticleYear
Update on thalassemia treatment in Taiwan, including bone marrow transplantation, chelation therapy, and cardiomyopathy treatment effects.
    Hemoglobin, 2009, Volume: 33, Issue:5

    Topics: Benzoates; beta-Thalassemia; Blood Transfusion; Bone Marrow Transplantation; Cardiomyopathies; Chela

2009
Cardiac events and cardiac T2* in Egyptian children and young adults with beta-thalassemia major taking deferoxamine.
    Hematology/oncology and stem cell therapy, 2010, Volume: 3, Issue:4

    Topics: Adolescent; Age Factors; Benzoates; beta-Thalassemia; Child; Child, Preschool; Death; Deferasirox; D

2010
[The treatment of siderosis by desferrioxamine B. Comparison with the action of 2 other chelating agents].
    La Presse medicale, 1962, Dec-29, Volume: 70

    Topics: Chelating Agents; Deferoxamine; Edetic Acid; Humans; Siderosis

1962
THE TREATMENT OF IRON OVERLOAD WITH DESFERRIOXAMINE B.
    Irish journal of medical science, 1964, Volume: 457

    Topics: Anemia; Anemia, Aplastic; Blood Transfusion; Deferoxamine; Humans; Hydroxamic Acids; Iron Chelating

1964
SUBSTITUTIVE-INHIBITORY THERAPY IN CONSTITUTIONAL NON-SPHEROCYTIC ERYTHROCYTIC DISEASE.
    Acta haematologica, 1964, Volume: 31

    Topics: Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Congenital Nonspherocytic; Blood Transfusion; Deferoxa

1964
[A NEW TEST FOR ASCERTAINMENT OF STATES OF SIDEROSIS: THE DESFERRIOXAMINE TEST. PRELIMINARY RESULTS].
    Il Policlinico. Sezione pratica, 1964, Jul-20, Volume: 71

    Topics: Anemia; Anemia, Hypochromic; Biomedical Research; Deferoxamine; Hematologic Diseases; Hemochromatosi

1964
[DESFERRIOXAMINE (DF) AND DIETHYLENE TRIAMINE PENTA-ACETIC ACID TRISODIUM CALCIUM SALT (CA DTPA NA3) IN SIDEROSIS. 2].
    La Presse medicale, 1965, Jan-09, Volume: 73

    Topics: Anemia; Anemia, Hypochromic; Blood Transfusion; Calcium; Chelating Agents; Deferoxamine; Drug Therap

1965
[SOMETHING NEW FOR THE TREATMENT OF SIDEROSIS].
    Folha medica, 1964, Volume: 48

    Topics: Deferoxamine; Hemochromatosis; Humans; Siderosis

1964
[TRIAL OF A NEW IRON CHELATOR, DESFERRIOXAMINE B, IN A CASE OF OCULAR SIDEROSIS].
    Bulletin des societes d'ophtalmologie de France, 1964, Volume: 64

    Topics: Chelating Agents; Deferoxamine; Eye Diseases; Heavy Metal Poisoning; Humans; Iron; Iron Metabolism D

1964
[USE OF DESFERRIOXAMINE B IN DIAGNOSIS AND THERAPY OF HYPERSIDEROSIS].
    Giornale di clinica medica, 1964, Volume: 45

    Topics: Deferoxamine; Humans; Siderosis

1964
[ON THE TREATMENT OF HEPATIC SIDEROSIS].
    Wiener klinische Wochenschrift, 1964, Dec-11, Volume: 76

    Topics: Deferoxamine; Drug Therapy; Hemochromatosis; Hepatolenticular Degeneration; Humans; Liver Diseases;

1964
Oral iron chelators: new opportunities and new dilemmas.
    Haematologica, 2006, Volume: 91, Issue:10

    Topics: Administration, Oral; Animals; Deferoxamine; Humans; Iron Chelating Agents; Iron Overload; Siderosis

2006
Desferrioxamine B in ophthalmology. Applications and therapeutic possibilities.
    American journal of ophthalmology, 1967, Volume: 63, Issue:1

    Topics: Adult; Animals; Cornea; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Humans; Male; Rabbits; Sider

1967
Hypersiderosis.
    Medical times, 1967, Volume: 95, Issue:4

    Topics: Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Siderosis

1967
Cirrhosis with secondary siderosis or primary haemochromatosis.
    Proceedings of the Royal Society of Medicine, 1967, Volume: 60, Issue:12

    Topics: Alcoholism; Deferoxamine; Diagnosis, Differential; Hemochromatosis; Humans; Iron; Iron Isotopes; Liv

1967
Twenty-four hour desferrioxamine test in normal, iron deficient and hypersideraemic (both hypersiderotic and non-hypersiderotic) subjects.
    Panminerva medica, 1967, Volume: 9, Issue:6

    Topics: Adult; Deferoxamine; Deficiency Diseases; Hepatitis A; Humans; Iron; Middle Aged; Siderosis

1967
Siderosis, haemolysis or hepatonecrosis in increasing post-desferrioxamine sideruria in acute viral hepatitis?
    Postgraduate medical journal, 1967, Volume: 43, Issue:505

    Topics: Deferoxamine; Hemolysis; Hepatitis A; Humans; Iron; Liver Diseases; Necrosis; Siderosis

1967
Iron chelation with oral desferrioxamine.
    Lancet (London, England), 1980, Oct-11, Volume: 2, Issue:8198

    Topics: Deferoxamine; Humans; Siderosis; Transfusion Reaction

1980
Reduction of iron overload in thalassemia.
    Birth defects original article series, 1982, Volume: 18, Issue:7

    Topics: Adolescent; Adult; Aging; Animals; Cell Separation; Child; Child, Preschool; Deferoxamine; Erythrocy

1982
Experimental siderosis of articular chondrocytes cultured in vitro.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:6

    Topics: Animals; Ascorbic Acid; Cartilage, Articular; Cattle; Cells, Cultured; Deferoxamine; Disease Models,

1981
Continuous intra-venous (CIV) infusion of desferrioxamine (DF) in a hemodialysed patient with transfusion siderosis.
    The International journal of artificial organs, 1981, Volume: 4, Issue:2

    Topics: Adult; Deferoxamine; Humans; Infusions, Parenteral; Male; Renal Dialysis; Siderosis; Transfusion Rea

1981
Desferrioxamine in ocular siderosis: a long-term electrophysiological evaluation.
    The British journal of ophthalmology, 1980, Volume: 64, Issue:8

    Topics: Animals; Deferoxamine; Electroretinography; Eye Diseases; Eye Foreign Bodies; Rabbits; Siderosis

1980
[Clinical aspects of ocular siderosis].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Aug-11, Volume: 35, Issue:32

    Topics: Adult; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Humans; Hydroxamic Acids; Iron; Male; Sideros

1980
Prevention of heart disease by subcutaneous desferrioxamine in patients with thalassaemia major.
    Australian and New Zealand journal of medicine, 1993, Volume: 23, Issue:6

    Topics: Adolescent; Adult; beta-Thalassemia; Cardiomyopathies; Child; Deferoxamine; Electrocardiography; Fem

1993
Congenital erythropoietic porphyria associated with nephrotic syndrome and renal siderosis.
    Acta paediatrica (Oslo, Norway : 1992), 1995, Volume: 84, Issue:11

    Topics: Anti-Inflammatory Agents; Child; Deferoxamine; Glomerular Filtration Rate; Humans; Iron Chelating Ag

1995
T2 relaxation rate as an index of pituitary iron overload in patients with beta-thalassemia major.
    AJR. American journal of roentgenology, 2000, Volume: 175, Issue:6

    Topics: Adult; beta-Thalassemia; Case-Control Studies; Chelating Agents; Deferoxamine; Female; Ferritins; Hu

2000
[Experience with desferrioxamine treatment by slow subcutaneous administration, in thalassemia].
    Minerva pediatrica, 1979, May-31, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Child; Deferoxamine; Female; Humans; Injections, Intramuscular; Male; Siderosis;

1979
[Experience with desferrioxamine treatment by intravenous administration, in thalassemia].
    Minerva pediatrica, 1979, May-31, Volume: 31, Issue:10

    Topics: Child; Deferoxamine; Female; Humans; Infusions, Parenteral; Male; Siderosis; Thalassemia; Transfusio

1979
Intravenous or subcutaneous deferoxamine for iron overload?
    The New England journal of medicine, 1978, Feb-16, Volume: 298, Issue:7

    Topics: Deferoxamine; Humans; Infusions, Parenteral; Injections, Subcutaneous; Siderosis

1978
[Controlled desferrioxamine treatment of congenital anaemia and transfusion siderosis (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Aug-04, Volume: 103, Issue:31

    Topics: Adolescent; Anemia, Aplastic; Child; Deferoxamine; Erythrocytes, Abnormal; Humans; Iron; Male; Sider

1978
Safety of intensive chelation therapy.
    The New England journal of medicine, 1977, Jan-13, Volume: 296, Issue:2

    Topics: Adolescent; Adult; Ascorbic Acid; Deferoxamine; Drug Synergism; Humans; Siderosis

1977
[Iron storage disease].
    Deutsche medizinische Wochenschrift (1946), 1977, Feb-18, Volume: 102, Issue:7

    Topics: Deferoxamine; Diagnosis, Differential; Hemochromatosis; Humans; Siderosis

1977
Continuous subcutaneous administration of deferoxamine in patients with iron overload.
    The New England journal of medicine, 1977, 08-25, Volume: 297, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Aged; Ascorbic Acid; Child; Child, Preschool; Deferoxamine;

1977
[Letter: Therapy of hemochromatosis].
    Medizinische Klinik, 1975, Jan-17, Volume: 70, Issue:3-2

    Topics: Bloodletting; Deferoxamine; Hemochromatosis; Humans; Porphyrias; Siderosis

1975
Transfusional iron overload: the relationship between tissue iron concentration and hepatic fibrosis in thalassaemia.
    The Journal of pathology, 1975, Volume: 116, Issue:2

    Topics: Adolescent; Adult; Age Factors; Biopsy; Child; Child, Preschool; Deferoxamine; Humans; Iron; Iron Ch

1975
[Adapto-electroretinography (AERG); siderosis due to intraocular foreign body, and Desferal].
    Bulletin des societes d'ophtalmologie de France, 1975, Volume: 75, Issue:1

    Topics: Adult; Deferoxamine; Electroretinography; Eye Foreign Bodies; Humans; Male; Siderosis

1975
Electroretinographic and visual-evoked potential abnormalities in patients with beta-thalassemia major.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1988, Volume: 196, Issue:1

    Topics: Adolescent; Adult; Child; Deferoxamine; Electroretinography; Evoked Potentials, Visual; Eye; Humans;

1988
[Therapeutical procedures for iron foreign bodies in the orbit].
    Klinika oczna, 1987, Volume: 89, Issue:1

    Topics: Animals; Deferoxamine; Eye; Eye Foreign Bodies; Iron; Orbit; Rabbits; Siderosis

1987
High dosage desferrioxamine therapy in a female patient with acquired aplastic anaemia and transfusion siderosis.
    Blut, 1986, Volume: 52, Issue:4

    Topics: Adult; Anemia, Aplastic; Bone Marrow; Deferoxamine; Feces; Female; Ferritins; Humans; Iron; Siderosi

1986
Studies on the use of desferrioxamine in experimental ocular siderosis produced by extrabulbar administration of iron.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1985, Volume: 223, Issue:2

    Topics: Animals; Deferoxamine; Eye; Eye Diseases; Eye Foreign Bodies; Iron; Rabbits; Siderosis

1985
Site of action of desferrioxamine in removing iron in normal and pathological conditions.
    Acta haematologica, 1974, Volume: 51, Issue:3

    Topics: Anemia; Animals; Brain Chemistry; Deferoxamine; Heart; Infusions, Parenteral; Iron; Iron-Dextran Com

1974
[Diagnosis and therapy of iron-deficiency and sideroachrestic anemias].
    Munchener medizinische Wochenschrift (1950), 1973, Mar-23, Volume: 115, Issue:12

    Topics: Anemia, Hypochromic; Anemia, Macrocytic; Bloodletting; Deferoxamine; Hemochromatosis; Humans; Iron;

1973
[Effectiveness of Desferal in diseases occurring simultaneously with hypersiderosis].
    Klinicheskaia meditsina, 1973, Volume: 51, Issue:8

    Topics: Adult; Anemia, Aplastic; Deferoxamine; Humans; Middle Aged; Siderosis

1973
[The diagnostic value of the desferrioxamine B test in the latent form of primary idiopathic hemochromatosis].
    Acta biologica et medica Germanica, 1966, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Child; Deferoxamine; Edetic Acid; Female; Hemochromatosis; Humans; Iron; Male; Mi

1966
[Cytosiderosis and deposits of iron in the ventrolateral nucleus of the thalamus in Parkinson's disease. Clinical and experimental study].
    Revue neurologique, 1969, Volume: 121, Issue:6

    Topics: Animals; Cerebral Cortex; Cytoplasmic Granules; Deferoxamine; Electromyography; Ferritins; Haplorhin

1969
Diagnosis of iron storage disease with desferrioxamine (Desferal test).
    Acta haematologica, 1964, Volume: 32, Issue:6

    Topics: Anemia, Macrocytic; Anemia, Sickle Cell; Deferoxamine; Female; Hemochromatosis; Hemosiderosis; Human

1964
[Therapy of primary siderochromatosis and siderosis: experimental and clinical study].
    Minerva medica, 1969, Dec-03, Volume: 60, Issue:97

    Topics: Bloodletting; Deferoxamine; Hemochromatosis; Humans; Intestinal Absorption; Iron; Porphyrias; Primar

1969
The effect of ascorbic acid deficiency on desferrioxamine-induced urinary iron excretion.
    British journal of haematology, 1969, Volume: 17, Issue:6

    Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Deferoxamine; Hemochromatosis; Humans; Iron; Leukocytes; Ma

1969
Differential ferrioxamine test in haemochromatosis and liver diseases.
    Gut, 1969, Volume: 10, Issue:9

    Topics: Adult; Bloodletting; Cholestasis; Deferoxamine; Diagnosis, Differential; Female; Hemochromatosis; Hu

1969
[Clinical and experimental results of the treatment of some ocular diseases with desferrioxamine B].
    Annali di ottalmologia e clinica oculistica, 1969, Volume: 95, Issue:3

    Topics: Adolescent; Adult; Animals; Cornea; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Hemorrhage; Huma

1969
Phlebotomy therapy in cutaneous porphyria. Effect on iron and trace metals.
    Archives of dermatology, 1970, Volume: 101, Issue:2

    Topics: Aged; Bloodletting; Copper; Deferoxamine; Hematopoiesis; Humans; Iron; Liver Function Tests; Magnesi

1970
Storage iron and desferrioxamine.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; De

1970
[Inveterate leg ulcer in a constitutional hemolytic syndrome with dermosiderosis. Cure by desfrrioxamine].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1967, Volume: 74, Issue:4

    Topics: Adult; Deferoxamine; Humans; Leg Ulcer; Male; Siderosis; Skin Diseases; Thalassemia

1967
[Research on the desferrioxamine test in welders].
    Folia medica. Folia medica (Naples, Italy), 1967, Volume: 50, Issue:7

    Topics: Adult; Deferoxamine; Humans; Iron; Lung Diseases; Middle Aged; Occupational Diseases; Siderosis; Wel

1967
[Case of ocular siderosis ameliorated by deferoxamine].
    Bulletin des societes d'ophtalmologie de France, 1967, Volume: 67, Issue:11

    Topics: Deferoxamine; Electroretinography; Eye Diseases; Humans; Male; Middle Aged; Siderosis

1967
[Favorable clinical and biological action of iron chelator in 4 cases of porphyria cutanea tarda. Attempts at interpretation].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1968, Volume: 75, Issue:5

    Topics: Adult; Aged; Alcoholism; Deferoxamine; Humans; Male; Porphyrias; Siderosis; Skin Diseases

1968
[Treatment of ocular siderosis with desferrioxamine B].
    Annali di ottalmologia e clinica oculistica, 1968, Volume: 94, Issue:5

    Topics: Adolescent; Adult; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Eye Injuries; Humans; Male; Sider

1968
Effect of desferrioxamine B. A new iron eliminating agent, on cases of secondary haemosiderosis in children.
    The Journal of tropical medicine and hygiene, 1969, Volume: 72, Issue:1

    Topics: Child; Child, Preschool; Deferoxamine; Female; Hemosiderosis; Humans; Iron; Liver; Male; Siderosis;

1969
[Chemica damage to the eye in industrial medicine].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1969, Volume: 1-3, Issue:1

    Topics: Argyria; Burns, Chemical; Caustics; Chelating Agents; Chronic Disease; Copper; Deferoxamine; Dimerca

1969
[The desferrioxamine test in diagnosis of siderosis].
    Il Policlinico. Sezione medica, 1965, Volume: 72, Issue:3

    Topics: Deferoxamine; Humans; Siderosis

1965
[Use of desferrioxamine B in the treatment of post-transfusion hypersiderosis].
    Marseille medical, 1965, Volume: 102, Issue:7

    Topics: Adolescent; Anemia, Hemolytic; Child; Child, Preschool; Deferoxamine; Female; Humans; Male; Siderosi

1965
[Applications of a new chelating substance in ophthalmology. Therapeutic results in a case of ocular siderosis treated with desferrioxamine B].
    Annali di ottalmologia e clinica oculistica, 1965, Volume: 91, Issue:7

    Topics: Adult; Deferoxamine; Eye Diseases; Eye Foreign Bodies; Female; Humans; Siderosis

1965
[The treatment of siderosis: elective activity of desferrioxamine B].
    Semaine therapeutique, 1963, Volume: 39, Issue:9

    Topics: Deferoxamine; Humans; Siderosis

1963
[Observations on the behavior of iron in the human organism after administration of desferrioxamine].
    Acta isotopica, 1965, Oct-31, Volume: 5, Issue:2

    Topics: Deferoxamine; Female; Humans; In Vitro Techniques; Iron; Male; Siderosis

1965
[Recent progress in diagnosis of siderosis: the desferrioxamine test].
    Recenti progressi in medicina, 1965, Volume: 39, Issue:2

    Topics: Deferoxamine; Humans; Siderosis

1965
[Specific treatment of excessive iron deposition in the tissues].
    Polskie Archiwum Medycyny Wewnetrznej, 1965, Volume: 35, Issue:1

    Topics: Administration, Oral; Bloodletting; Chelating Agents; Connective Tissue; Deferoxamine; Hemochromatos

1965
Treatment of acute iron ingestion with deferoxamine in 20 children.
    The Journal of pediatrics, 1966, Volume: 68, Issue:5

    Topics: Child, Preschool; Deferoxamine; Humans; Infant; Siderosis

1966
Treatment of experimental siderosis bulbi, vitreous hemorrhage, and corneal blood staining with deferoxamine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1966, Volume: 75, Issue:5

    Topics: Animals; Blood Stains; Cornea; Deferoxamine; Eye Diseases; Hemorrhage; In Vitro Techniques; Rabbits;

1966
Treatment of ocular siderosis and haemochromatosis with desferrioxamine.
    Acta ophthalmologica, 1966, Volume: 44, Issue:1

    Topics: Deferoxamine; Eye Diseases; Eye Foreign Bodies; Eye Injuries; Hemorrhage; Humans; Injections, Intram

1966
[Respective variations of sideremia and sideruria in cirrhotic patients following the desferrioxamine B test].
    Archives francaises des maladies de l'appareil digestif, 1966, Volume: 55, Issue:9

    Topics: Deferoxamine; Hemosiderosis; Humans; Iron; Liver Cirrhosis; Siderosis

1966
[Our experience with desferrioxamine B in the treatment of ocular siderosis (apropos of 6 cases)].
    Bulletin des societes d'ophtalmologie de France, 1966, Volume: 66, Issue:9

    Topics: Adult; Deferoxamine; Eye Foreign Bodies; Humans; Male; Middle Aged; Siderosis

1966
[Respective variations of iron in blood and urine in cirrhotic and alcoholic patients after a desferrioxamine test].
    Archives francaises des maladies de l'appareil digestif, 1966, Volume: 55, Issue:12

    Topics: Alcoholism; Deferoxamine; Diagnosis, Differential; Female; Hemochromatosis; Humans; Iron; Liver Cirr

1966