Page last updated: 2024-09-28

Chromosomal Fragility

Susceptibility of chromosomes to breakage leading to translocation; CHROMOSOME INVERSION; SEQUENCE DELETION; or other CHROMOSOME BREAKAGE related aberrations.

Synonyms(2)

Synonym
Chromosome Fragility
Chromosomal Fragility

Research Excerpts

Research

Studies (370)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990159 (42.97)23.3326
1990's158 (42.70)12.5806
2000's41 (11.08)18.1394
2010's12 (3.24)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetylcarnitine0low10
acetaldehyde0low10
butyric acid0low10
salicylic acid0low10
phosphonoacetic acid0low10
cytosine0low30
niacin0low10
sulfites0low20
thymine0low20
uracil0low40
urea0low10
phenytoin0low10
theophylline0low10
atenolol0low10
diminazene0low10
bisbenzimidazole0low20
caffeine0medium271
dapi0low60
diazepam0low10
stallimycin0low220
valproic acid0low10
fluorouracil0low10
guaifenesin0low10
ethidium0low20
hydroxyurea0low50
2-propanol0low10
methyl methanesulfonate0low10
netropsin0low10
pyrimethamine0low20
trimethoprim0low40
mitomycin0low160
lysergic acid diethylamide0low10
thymidine0low190
floxuridine0medium431
idoxuridine0low10
4-nitroquinoline-1-oxide0low20
aspartic acid0low10
uridine0low20
bromodeoxyuridine0low500
ethyl methanesulfonate0low30
methionine0low50
cytidine0low10
cytarabine0medium61
histidine0low40
dimethyl sulfate0low10
tromethamine0low10
deanol0medium11
pyrroles0low70
tecnazene0low10
hydrazine0low10
azacitidine0low90
thymidine monophosphate0low10
2-aminopurine0low10
azomycin0low10
diepoxybutane0low40
malachite green0low10
acetylcysteine0low10
c.i. 425100low10
methylnitrosourea0low20
deoxycytidine0low20
deoxyuridine0low20
vidarabine0low20
silver0low10
camptothecin0low10
coformycin0low10
tetradecanoylphorbol acetate0low20
osmium tetroxide0low10
benzonidazole0low10
etoposide0low10
7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide0low10
u 777790low10
adenosine0low10
5-methylcytosine0low10
2'-deoxyuridylic acid0low10
leucomalachite green0low10
7-hydroxystaurosporine0low10
pacein0low10
pyrimidine dimers0low10
hydrogen sulfite0low20
bromoacetaldehyde0low10
triptolide0low10
methotrexate0low210
aminopterin0low10
demecolcine0low10
benzofurans0low10
permanganate0low20
decitabine0low20
dactinomycin0low30
aphidicolin0medium1002
melphalan0low10
bromodeoxycytidine0low10
isomethyleugenol0low170
fludarabine0low10
tamoxifen0low10
olivomycins0low10
ku 559330low10
phenylephrine hydrochloride0low10
diminazene aceturate0low10
ammonium sulfate0low10
nifurtimox0low10
staurosporine0low10
mocetinostat0low10
n(4)-aminocytidine0low10
nad0low10
oligonucleotides0low10
s-adenosylmethionine0low10
hydroxocobalamin0medium11
ascorbic acid0low20
transforming growth factor beta0low10
agar0low10
cyclin d10low20
vitamin b 120low10
levoleucovorin0medium31
guanine0low20
guanosine0low20
folic acid0medium812
methylnitronitrosoguanidine0low10
cytidylyl-3'-5'-guanosine0low50
metallothionein0low10
phosphorus radioisotopes0low10
phenanthrenes0low10

Protein Targets (972)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Beta-lactamase6006
thioredoxin reductase150015
aldehyde dehydrogenase 1 family, member A1220022
IDH1150015
Phosphatidylinositol 4-kinase alpha0405
Xanthine dehydrogenase/oxidase0202
Guanine nucleotide-binding protein G4004
TAR DNA-binding protein 437007
Phosphatidylinositol 4-kinase type 2-beta0405
Phosphatidylinositol 4-kinase type 2-alpha0405
Phosphatidylinositol 4-kinase beta0405
hypoxia-inducible factor 1 alpha subunit120012
RAR-related orphan receptor gamma300030
GLI family zinc finger 3290029
AR protein430043
retinoic acid nuclear receptor alpha variant 1310031
retinoid X nuclear receptor alpha290029
estrogen nuclear receptor alpha480048
peroxisome proliferator-activated receptor delta170017
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
activating transcription factor 6110011
v-jun sarcoma virus 17 oncogene homolog (avian)160016
Histone H2A.x200020
thyroid hormone receptor beta isoform a110011
heat shock protein beta-1100010
nuclear factor erythroid 2-related factor 2 isoform 1290029
lamin isoform A-delta10210021
Voltage-dependent calcium channel gamma-2 subunit200020
Glutamate receptor 2200020
Chain A, Protein (thymidylate Synthase)0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Chain A, Thymidylate Synthase0011
Thymidylate synthase 0102
Thymidylate synthase0304
Thymidylate synthase0607
Thymidylate synthase0608
Thymidylate kinase0204
Gonadotropin-releasing hormone receptor0101
Thymidylate kinase0305
Thymidylate synthase 0101
Deoxyuridine triphosphatase, putative 0101
Serine/threonine-protein kinase Chk10213
3-phosphoinositide-dependent protein kinase 10101
Cyclin-dependent kinase 10101
Cyclin-dependent kinase 40101
Cyclin-A20101
G1/S-specific cyclin-D10101
Cyclin-dependent kinase 20112
acetylcholinesterase110011
SMAD family member 2110011
SMAD family member 3110011
caspase 7, apoptosis-related cysteine protease100010
thyroid stimulating hormone receptor9009
estrogen receptor 2 (ER beta)150015
nuclear receptor subfamily 1, group I, member 3290029
progesterone receptor200020
glucocorticoid receptor [Homo sapiens]300030
estrogen-related nuclear receptor alpha380038
farnesoid X nuclear receptor220022
pregnane X nuclear receptor260026
peroxisome proliferator activated receptor gamma200020
vitamin D (1,25- dihydroxyvitamin D3) receptor210021
caspase-3100010
thyroid stimulating hormone receptor140014
thyrotropin-releasing hormone receptor5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a110011
Caspase-76006
caspase-36006
thyroid hormone receptor beta isoform 2290029
Cellular tumor antigen p53280028
ATPase family AAA domain-containing protein 5190019
Ataxin-2210021
Chain A, JmjC domain-containing histone demethylation protein 3A5005
Chain A, 2-oxoglutarate Oxygenase7007
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
dopamine D1 receptor3003
15-lipoxygenase, partial7007
pregnane X receptor7007
phosphopantetheinyl transferase110011
USP1 protein, partial100010
NFKB1 protein, partial6006
Microtubule-associated protein tau120012
Thrombopoietin5005
regulator of G-protein signaling 47007
arylsulfatase A9009
euchromatic histone-lysine N-methyltransferase 2230023
Bloom syndrome protein isoform 1130013
D(1A) dopamine receptor4004
flap endonuclease 19009
geminin340034
peripheral myelin protein 22160016
survival motor neuron protein isoform d150015
muscarinic acetylcholine receptor M16006
Histone deacetylase 30808
Solute carrier family 22 member 60202
Histone deacetylase 40707
Histone deacetylase 10808
Histone deacetylase 70707
Histone deacetylase 20808
Polyamine deacetylase HDAC100505
Histone deacetylase 11 0606
Histone deacetylase 80707
Histone deacetylase 60707
Histone deacetylase 90606
Histone deacetylase 50707
ATP-dependent phosphofructokinase9009
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE190019
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
NPYLR7B0011
glycogen synthase kinase-3 beta isoform 10033
mitogen-activated protein kinase 13003
nuclear receptor ROR-gamma isoform 1110011
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10404
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20505
Rap guanine nucleotide exchange factor 35005
Purine nucleoside phosphorylase0304
Epidermal growth factor receptor0303
Phosphoglycerate kinase 1 0101
Adenosine deaminase0102
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0303
Receptor tyrosine-protein kinase erbB-20202
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A307210
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0103
Adenosine receptor A10519
Adenosine receptor A30404
Adenosine receptor A2a08516
Adenosine receptor A2b0216
Adenosine receptor A2b0417
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A108417
Adenosine receptor A2a04110
Adenylate kinase isoenzyme 1 0101
Adenosine receptor A10213
Adenosine kinase0001
Adenosine deaminase 0104
Equilibrative nucleoside transporter 20404
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10404
Solute carrier family 28 member 30404
Adenosine kinase0102
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
TDP1 protein320032
Dihydrofolate reductase0809
Dihydrofolate reductase0507
Dihydrofolate reductase0507
5-hydroxytryptamine receptor 2C0204
Dihydrofolate reductase07412
Folylpolyglutamate synthase, mitochondrial0206
Solute carrier organic anion transporter family member 1A30203
Folylpolyglutamate synthase, mitochondrial0106
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
huntingtin isoform 26006
DNA polymerase catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase beta0101
DNA polymerase beta0101
DNA polymerase catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase alpha catalytic subunit0112
DNA polymerase delta catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase subunit gamma-10101
DNA polymerase lambda0101
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase3003
cytochrome P450 family 3 subfamily A polypeptide 4140014
chromobox protein homolog 1190019
nuclear factor erythroid 2-related factor 2 isoform 2150015
lethal(3)malignant brain tumor-like protein 1 isoform I1001
lethal factor (plasmid)9009
Polyphenol oxidase 20304
Pancreatic alpha-amylase0202
Albumin0101
Urease0202
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0213
Spike glycoprotein130114
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE110011
Chain A, Ferritin light chain8008
cytochrome P450 2C19 precursor4004
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 10407
Carbonic anhydrase 205110
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0103
Glutamate receptor ionotropic, NMDA 1 0103
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0103
Glutamate receptor ionotropic, NMDA 2B0103
Glutamate receptor ionotropic, NMDA 2C0103
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0103
Glutamate receptor ionotropic, NMDA 3B0103
Carbonic anhydrase 40002
Glutamate receptor ionotropic, NMDA 3A0103
Beta-1 adrenergic receptor 0011
DNA polymerase iota isoform a (long)120012
Gamma-aminobutyric acid receptor subunit pi93214
ATP-binding cassette sub-family C member 3015015
Multidrug resistance-associated protein 4015017
Bile salt export pump020020
Fatty acid-binding protein, liver0202
Beta-2 adrenergic receptor0314
Beta-1 adrenergic receptor0516
Beta-3 adrenergic receptor0213
Gamma-aminobutyric acid receptor subunit beta-193214
Gamma-aminobutyric acid receptor subunit delta93214
Gamma-aminobutyric acid receptor subunit gamma-293214
5-hydroxytryptamine receptor 1A08210
Gamma-aminobutyric acid receptor subunit alpha-593214
Gamma-aminobutyric acid receptor subunit alpha-393214
Gamma-aminobutyric acid receptor subunit gamma-193214
Gamma-aminobutyric acid receptor subunit alpha-293214
Alpha-1D adrenergic receptor0303
Gamma-aminobutyric acid receptor subunit alpha-493214
Gamma-aminobutyric acid receptor subunit gamma-393214
Gamma-aminobutyric acid receptor subunit alpha-693214
Alpha-1A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
Gamma-aminobutyric acid receptor subunit alpha-193214
Gamma-aminobutyric acid receptor subunit beta-393214
Gamma-aminobutyric acid receptor subunit beta-293214
Beta-2 adrenergic receptor0011
GABA theta subunit93214
Canalicular multispecific organic anion transporter 1015016
Gamma-aminobutyric acid receptor subunit epsilon93214
interleukin 88008
glp-1 receptor, partial120012
ATAD5 protein, partial9009
Fumarate hydratase120012
PPM1D protein7007
Smad37007
polyprotein120012
67.9K protein190019
Parkin2002
aryl hydrocarbon receptor7007
peripheral myelin protein 22 isoform 16006
hemoglobin subunit beta3003
cellular tumor antigen p53 isoform a8008
ras-related protein Rab-9A5005
serine/threonine-protein kinase mTOR isoform 17007
urokinase-type plasminogen activator precursor110011
plasminogen precursor110011
urokinase plasminogen activator surface receptor precursor110011
histone acetyltransferase KAT2A isoform 16006
Interferon beta140014
Integrin beta-36006
Integrin alpha-IIb6006
DNA (cytosine-5)-methyltransferase 10202
D(1A) dopamine receptor5005
Nuclear receptor ROR-gamma9009
Multidrug and toxin extrusion protein 10202
Histone-lysine N-methyltransferase EHMT20202
EWS/FLI fusion protein170017
Cytochrome P450 1A20101
Cytochrome P450 3A40505
Cytochrome P450 2D60202
Cytochrome P450 2C9 0617
Cytochrome P450 2C190202
Potassium voltage-gated channel subfamily H member 20606
Aurora kinase B0101
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
Luciferase5005
nonstructural protein 15005
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 17007
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
DNA topoisomerase 105111
DNA topoisomerase 2-alpha0319
Histamine H2 receptor4004
DNA topoisomerase 2-beta01110
bromodomain adjacent to zinc finger domain 2B5005
nuclear receptor subfamily 1, group I, member 25005
Nuclear hormone receptor family member daf-120011
oxysterols receptor LXR-beta isoform 10011
Thymidine kinase, cytosolic05010
Thymidine phosphorylase0005
Thymidine kinase0004
Chain A, Nitrile Hydratase alpha subunit0101
Chain B, Nitrile Hydratase beta subunit0101
Lysine-specific demethylase 4E0101
Free fatty acid receptor 30011
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Methyl-accepting chemotaxis protein NahY0011
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
GLS protein7007
atrial natriuretic peptide receptor 1 precursor2002
DNA polymerase beta3003
DNA polymerase kappa isoform 16006
Potassium channel subfamily K member 20022
Glycogen phosphorylase, muscle form0101
Renin0202
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0213
Replicase polyprotein 1ab0213
Amine oxidase [flavin-containing] A0101
Acetylcholinesterase0202
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Vasopressin V2 receptor0002
Serine/threonine-protein kinase mTOR0202
Adenosine receptor A2a0202
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0303
DNA-dependent protein kinase catalytic subunit0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10002
Chitotriosidase-10202
Serine-protein kinase ATM0303
Serine/threonine-protein kinase ATR0202
Adenosine receptor A2b0103
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0134
Endochitinase B10202
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Guanine deaminase0102
Chain A, Cruzipain3003
DNA topoisomerase 0101
glucocerebrosidase5005
putative alpha-glucosidase1001
alpha-galactosidase3003
lysosomal alpha-glucosidase preproprotein4004
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
cytochrome P450 3A4 isoform 19009
M-phase phosphoprotein 85005
muscleblind-like protein 1 isoform 13003
relaxin receptor 1 isoform 11001
Telomerase reverse transcriptase0101
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
Prothrombin0002
DNA ligase0101
Heterogeneous nuclear ribonucleoprotein A10011
Type-2 restriction enzyme BamHI0101
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
5-hydroxytryptamine receptor 2B0505
Type-2 restriction enzyme HindIII0101
Ribonuclease pancreatic0101
Inositol monophosphatase 16006
DNA topoisomerase 10102
DNA topoisomerase 10101
Integrase 0202
DNA topoisomerase type IB small subunit 0011
Tyrosyl-DNA phosphodiesterase 10101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
vitamin D3 receptor isoform VDRA6006
Caspase-20011
AMP deaminase 30101
Adenosine deaminase 0101
endonuclease IV5005
G7007
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0404
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
transactivating tegument protein VP16 [Human herpesvirus 1]0404
nuclear receptor coactivator 3 isoform a0404
Thymidine kinase 2, mitochondrial0101
HLA class I histocompatibility antigen, B alpha chain 7007
Thymidine kinase0203
Thymidine kinase0101
Deoxycytidine kinase0003
Probable deoxycytidylate deaminase0002
Cytidine deaminase0205
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Inositol hexakisphosphate kinase 17007
Thymidine kinase0102
Deoxynucleoside kinase0101
cytochrome P450 2C9, partial7007
Glucose transporter0101
Cdk-related protein kinase 60101
Protein kinase domain-containing protein0101
Hexose transporter 1 0101
Solute carrier family 2, facilitated glucose transporter member 10101
Calcium-dependent protein kinase 10101
Mitogen-activated protein kinase 0101
Proline--tRNA ligase0101
Calcium-dependent protein kinase 40101
Lysine--tRNA ligase 0101
Uridine-cytidine kinase 1 0002
Deoxycytidine kinase0001
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
RAD510101
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
caspase-1 isoform alpha precursor2002
ATP-dependent translocase ABCB10418
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-72002
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0213
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Prothrombin 0101
Glandular kallikrein0101
Cell division protein FtsZ0012
Choline O-acetyltransferase 0101
potassium voltage-gated channel subfamily H member 2 isoform d5005
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
PAX80001
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
Nuclear receptor subfamily 1 group I member 20011
Tubulin beta-2B chain0202
Nuclear receptor subfamily 1 group I member 20011
Thymidine kinase 2 0101
AAA family ATPase 0001
Chain A, Dutpase0011
Chain A, Dutpase0011
Chain B, Dutpase0011
Chain A, Dutpase0011
Chain B, Dutpase0011
Gamma-aminobutyric acid 0202
Gamma-aminobutyric acid receptor subunit pi0404
Gamma-aminobutyric acid receptor subunit delta0404
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Alpha-1-acid glycoprotein 10001
Albumin0113
Albumin0011
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Neuronal acetylcholine receptor subunit alpha-42103
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit alpha-30202
Neuronal acetylcholine receptor subunit beta-22103
Gamma-aminobutyric acid receptor subunit alpha-10426
Translocator protein0113
Gamma-aminobutyric acid receptor subunit alpha-60202
Gamma-aminobutyric acid receptor subunit beta-10404
Gamma-aminobutyric acid receptor subunit gamma-20415
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit delta0202
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit alpha-30202
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit beta-30415
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50426
Gamma-aminobutyric acid receptor subunit alpha-30415
Gamma-aminobutyric acid receptor subunit alpha-20415
Gamma-aminobutyric acid receptor subunit beta-20415
Gamma-aminobutyric acid receptor subunit alpha-40404
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-30202
Gamma-aminobutyric acid receptor subunit epsilon0404
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Neuronal acetylcholine receptor subunit alpha-70101
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Gamma-aminobutyric acid receptor subunit alpha-60404
Gamma-aminobutyric acid receptor subunit alpha-50202
Gamma-aminobutyric acid receptor subunit gamma-10404
Gamma-aminobutyric acid receptor subunit pi0202
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit gamma-30404
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit theta0202
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit theta0404
Cathepsin B0101
Furin0101
Amiloride-sensitive amine oxidase [copper-containing]0101
Diamine acetyltransferase 10101
Acid-sensing ion channel 10101
Acid-sensing ion channel 20101
Regulatory protein E20011
ATP-dependent translocase ABCB10101
Polyunsaturated fatty acid lipoxygenase ALOX150101
DNA topoisomerase 20001
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0001
Serum paraoxonase/arylesterase 10101
Caspase-30101
DNA topoisomerase 2-alpha 0001
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Solute carrier organic anion transporter family member 1B30203
acid sphingomyelinase3003
BRCA11001
cytochrome P450 2D66006
P531001
histone deacetylase 9 isoform 32002
importin subunit beta-1 isoform 15005
nuclear factor NF-kappa-B p105 subunit isoform 11001
snurportin-15005
Glycoprotein hormones alpha chain1001
Retinol-binding protein 40022
Prosaposin0011
Retinoic acid receptor gamma 0101
Alpha-1B adrenergic receptor0303
Alpha-1A adrenergic receptor0101
Retinoic acid receptor RXR-alpha0101
Alpha-1D adrenergic receptor0101
Retinoic acid receptor RXR-beta0101
Indoleamine 2,3-dioxygenase 10101
Alpha-1A adrenergic receptor0303
Retinoic acid receptor RXR-gamma0101
Indoleamine 2,3-dioxygenase 20101
interferon gamma precursor0002
streptokinase A precursor0033
Solute carrier family 15 member 10101
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
5'-nucleotidase0101
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Vpr3003
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1102
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10202
Alpha-synuclein2002
Multidrug resistance associated protein0103
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Chain A, HISTIDINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Carbonic anhydrase 120102
Plasma kallikrein0001
Carbonic anhydrase 30102
Histidine-binding periplasmic protein0011
Carbonic anhydrase 40304
Carbonic anhydrase 60102
Carbonic anhydrase 5A, mitochondrial0203
Carbonic anhydrase0102
Carbonic anhydrase 70102
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10202
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90204
Carbonic anhydrase 0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Carbonic anhydrase 130001
Carbonic anhydrase 150203
Carbonic anhydrase 130102
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
Stromelysin-10022
Urease subunit alpha0202
Ribonucleoside-diphosphate reductase large subunit0101
Urease subunit beta0202
Thymidine kinase 0203
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0101
Chain A, HTH-type transcriptional regulator qacR0011
Chain B, HTH-type transcriptional regulator qacR0011
Chain A, HTH-type transcriptional regulator qacR0011
Chain B, HTH-type transcriptional regulator qacR0011
Chain A, HTH-type transcriptional regulator qacR0011
Chain A, HTH-type transcriptional regulator qacR0011
Chain B, HTH-type transcriptional regulator qacR0011
Chain A, HTH-type transcriptional regulator qacR0011
Chain B, HTH-type transcriptional regulator qacR0011
5-hydroxytryptamine receptor 1A0202
D(2) dopamine receptor0303
5-hydroxytryptamine receptor 2A0314
D(4) dopamine receptor0303
D(1B) dopamine receptor0101
Catechol O-methyltransferase0101
Sodium-dependent dopamine transporter0101
5-hydroxytryptamine receptor 2A0314
5-hydroxytryptamine receptor 2C0303
5-hydroxytryptamine receptor 1E0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0101
D(3) dopamine receptor0303
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 60303
Sodium-dependent dopamine transporter 0303
D0101
Sodium-dependent dopamine transporter0101
Large neutral amino acids transporter small subunit 1 0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 34004
DNA polymerase eta isoform 11001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0303
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase 0404
Dihydrofolate reductase0303
Dihydrofolate reductase0101
Tyrosine-protein kinase ABL10011
Bifunctional dihydrofolate reductase-thymidylate synthase0303
High mobility group protein B10022
Dihydrofolate reductase0303
Thymidylate synthase0202
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0505
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0607
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
6-phosphogluconate dehydrogenase, decarboxylating0101
Dihydrofolate reductase0202
Pteridine reductase 10202
Bifunctional dihydrofolate reductase-thymidylate synthase0304
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0303
Solute carrier family 22 member 80102
Dihydrofolate reductase0304
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40202
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Disintegrin and metalloproteinase domain-containing protein 171001
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Nuclear receptor corepressor 20101
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Plasminogen0101
Urokinase-type plasminogen activator0101
Trypsin-10101
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
60 kDa heat shock protein, mitochondrial0101
Trypanothione reductase0101
10 kDa heat shock protein, mitochondrial0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Chain A, Breast cancer type 1 susceptibility protein1001
cytochrome P450 2D6 isoform 13003
cytochrome P450 2C9 precursor2002
Platelet-activating factor receptor1001
Non-structural protein 1 0101
GALC protein2002
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 2 subunit alpha0101
Aldo-keto reductase family 1 member B10101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0102
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Chain A, Alkaline Phosphatase0101
Chain A, ALKALINE PHOSPHATASE0101
DNA polymerase III, partial2002
GTP-binding nuclear protein Ran isoform 11001
Fe(3+)-Zn(2+) purple acid phosphatase0101
dual specificity protein phosphatase 30101
low molecular weight phosphotyrosine protein phosphatase isoform c0101
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 10101
Solute carrier family 22 member 1 0202
Estrogen receptor0023
Beta-hexosaminidase subunit alpha0102
Beta-hexosaminidase subunit beta0101
Substance-K receptor0101
Dihydrofolate reductase0202
Low molecular weight phosphotyrosine protein phosphatase0101
Dipeptidyl peptidase 40303
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Trace amine-associated receptor 50022
Estrogen receptor beta0023
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Prostaglandin G/H synthase 10202
Cystathionine gamma-lyase0101
Prostaglandin G/H synthase 20202
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
GTPase HRas0101
Estrogen receptor0315
Neutrophil elastase0101
Histamine H1 receptor0112
Estrogen receptor beta0314
Chain A, Ribosomal protein S6 kinase alpha-10101
Chain X, Tyrosine-protein kinase Lyn0101
Chain A, Dual specificity protein kinase TTK0011
Chain A, Dual specificity protein kinase TTK0011
Chain A, CES1 protein0101
apical membrane antigen 1, AMA11001
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor2002
ubiquitin-conjugating enzyme E2 N0101
Transmembrane protease serine 20011
5-hydroxytryptamine receptor 40202
Serine/threonine-protein kinase D30112
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0213
Protein kinase C alpha type0101
Protein kinase C beta type0213
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Progesterone receptor0101
Procathepsin L0011
Aldo-keto reductase family 1 member B10303
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0203
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Muscarinic acetylcholine receptor M10202
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Angiotensin-converting enzyme0202
Androgen receptor0202
Protein kinase C alpha type0213
Muscarinic acetylcholine receptor M30202
Cytochrome P450 2B60101
Substance-K receptor0202
D(1A) dopamine receptor0202
UDP-glucuronosyltransferase 1A40001
Sodium-dependent noradrenaline transporter 0202
Thromboxane-A synthase 0101
Protein kinase C eta type0112
Histamine H2 receptor0202
Substance-P receptor0202
5-hydroxytryptamine receptor 1B0202
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Protein kinase C iota type0112
Melanocortin receptor 30202
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0213
Protein kinase C theta type0112
Protein kinase C zeta type0112
Protein kinase C delta type0213
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10112
Protein kinase C eta type0101
Nuclear receptor subfamily 3 group C member 3 0202
Sigma non-opioid intracellular receptor 10202
Emopamil-binding protein-like0101
Angiotensin-converting enzyme 2 0011
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Luciferin 4-monooxygenase0011
Beta-1 adrenergic receptor0101
Ras guanyl-releasing protein 30011
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Phosphodiesterase 0202
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
D(3) dopamine receptor0101
Adenosine receptor A10202
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Sigma non-opioid intracellular receptor 10202
Phospholipase A-2-activating protein0101
Thymidine phosphorylase0001
Thymidine kinase, cytosolic 0002
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Chain A, Thymidylate Synthase0011
Thymidine phosphorylase0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Dihydrofolate reductase0101
NH(3)-dependent NAD(+) synthetase0101
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Metabotropic glutamate receptor 50101
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20101
Mu-type opioid receptor0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase 0101
Dihydrofolate reductase 0101
Proteinase-activated receptor 20101
dCTP pyrophosphatase 10202
Chain A, CARBONIC ANHYDRASE II0101
Chain A, Uracil-DNA Glycosylase0101
Protein cereblon0404
Olfactory receptor 51E20011
Chain A, Cytidine Deaminase0101
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]