hydroxyurea has been researched along with Chromosomal Fragility in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxyurea (HU) is an inhibitor of DNA synthesis, which can inhibit the enzyme ribonucleotide reductase, reduce the syntheses of all four deoxyribonucleoside diphosphates (dNDP), and disturb the balance of the dNTP pool." | 1.27 | The effect of hydroxyurea on the expression of the common fragile site at 3p14. ( Li, XZ; Yan, ZA; Zhou, XT, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoffman, EA | 1 |
| McCulley, A | 1 |
| Haarer, B | 1 |
| Arnak, R | 1 |
| Feng, W | 1 |
| Freudenreich, CH | 2 |
| Kantrow, SM | 1 |
| Zakian, VA | 2 |
| Balakumaran, BS | 1 |
| Yan, ZA | 2 |
| Li, XZ | 2 |
| Zhou, XT | 2 |
5 other studies available for hydroxyurea and Chromosomal Fragility
| Article | Year |
|---|---|
Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription.
Topics: Cell Cycle; Chromosome Breakage; Chromosome Fragility; DNA Breaks, Double-Stranded; DNA Replication; | 2015 |
Expansion and length-dependent fragility of CTG repeats in yeast.
Topics: Chromosome Breakage; Chromosome Fragility; Chromosomes, Fungal; DNA Damage; DNA Repair; DNA Replicat | 1998 |
CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae.
Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Fungal; DNA Repair; DNA Repair Enzymes; | 2000 |
Synergistic effect of hydroxyurea and excessive thymidine on the expression of the common fragile sites at 3p14 and 16q23.
Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 16; Chromosomes, Human, Pai | 1988 |
The effect of hydroxyurea on the expression of the common fragile site at 3p14.
Topics: Caffeine; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human | 1987 |