Page last updated: 2024-08-17

folic acid and Chromosomal Fragility

folic acid has been researched along with Chromosomal Fragility in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	50 (61.73)	18.7374
1990's	26 (32.10)	18.2507
2000's	5 (6.17)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Demirhan, O; Sertdemir, Y; Tastemir, D	1
Ankathil, R; Krishnan Nair, M; Kusumakumary, P; Priyakumary, T	1
Moriarty, HT; Webster, LR	1
Kerem, B; Schwartz, M; Zlotorynski, E	1
Fryns, JP; Lukusa, T	1
Hecht, F; Jacky, PB; Sutherland, GR	1
Nielsen, KB; Tommerup, N	1
Soreng, AL; Yunis, JJ	1
Hagerman, PJ; Hagerman, RJ; McBogg, P	1
Jotterand-Bellomo, M	1
Arthur, DC; Branda, RF; Danzl, TJ; King, RA; Woods, WG	1
Chen, AT; Reidy, JA	1
Howard-Peebles, PN; Krumdieck, CL	1
Reidy, JA	3
Brooks, J; Brown, WT; Cohen, IL; Duncan, C; Friedman, E; Hill, AL; Jenkins, EC; Malik, MN; Morris, V; Wolf, E	1
Beek, B; Jacky, PB; Sutherland, GR	1
Wegner, RD	1
Baker, E; Jacky, PB; Manuel, A; Sutherland, GR	1
Harpey, JP	1
Lejeune, J	1
Sutherland, GR	3
Georgiou, I; Lolis, D; Paschopoulos, M; Syrrou, M	1
Denton, M; Holman, K; Hori, T; Mangelsdorf, M; Nancarrow, JK; Richards, RI; Sutherland, GR	1
Laxova, R	1
Baker, E; Sutherland, GR	3
Long, SE; Yang, MY	1
Barber, JC; Buckle, VJ; Davies, KE; Flannery, AV; Flynn, GA; Hirst, MC; Knight, SJ; Macpherson, JN	1
Doles, J; Stephens, KE; Stone, DM	1
Chudley, AE; Evans, JA; Samadder, P	1
Jennings, E	1
Arrieta, I; Flores, P; Gil, A; Martinez, B; Nuñez, T; Usobiaga, E	1
Leffers, H; Tommerup, N	1
Hori, T; Tsuji, S; Yamauchi, M	1
Courseaux, A; Gaudray, P; Grosgeorge, J; Hecht, BK; Hecht, F; Perucca-Lostanlen, D	1
Chen, CH; Shih, HH; Tai, JJ; Wang-Wuu, S; Wuu, KD	1
Chapman, CJ; Donnelly, A; Gardner, RJ; Gedeon, AK; Loesch, D; Mulley, JC; Richards, RI; Sutherland, GR; Turner, G; Yu, S	1
Bouchakliev, ZP; Gergov, TD; Toncheva, DI; Tzoneva, MT	1
Hancock, DD; Jacky, PB; Prieur, DJ; Stone, DM	1
Jacky, PB; Prieur, DJ; Stone, DM	1
Lufei, H	1
Evans, JL; Howell, RT; McDermott, A	1
Merkx, G; Smeets, DF	1
Cheang, M; Chudley, AE; Evans, JA; Ray, M	1
Kampmann, T; Pasarge, E; Rüdiger, HW; Schmidt, A; Tan, TL	1
Mariani, T; Piras, A; Rainaldi, G; Simi, S; Vatteroni, L	1
Butler, MG; Jenkins, BB	1
Airaksinen, E; Alitalo, T; Kähkönen, M; Kaski, M; Matilainen, R; Tengström, C	1
Annest, JL; Chen, AT; Reidy, JA; Welty, TK; Zhou, HG	1
Barrios, L; Egozcue, J; Fuster, C; Miró, R; Templado, C	2
Chapman, CJ; Columbano-Green, LM; Gebbie, OB; Parfitt, RG; Romain, DR; Smythe, RH	1
De Braekeleer, M	1
Kajii, T; Kuwano, A; Murano, I; Sugio, Y	1
Mikkelsen, M; Nielsen, J; Tommerup, N	1
Barbi, G; Djalali, M; Steinbach, P	1
Pelliccia, F; Rocchi, A	1
Kähkönen, M	1
Chen, AT; Green, RJ; Phillips, DL; Ragab, AH; Reidy, JA	1
Corson, VL; Norbury-Glaser, M; Sroka, B; Stetten, G	1
Butler, FO; Haney, SM; Heerema, NA	1
Hori, T; Murata, M; Takahashi, E	1
Bamezai, R; Husain, SA	1
Colantuoni, M; de Tollis, G; Della Monica, M; Fiore, M; Gentile, G; Lonardo, F; Perone, L; Sirone, P; Stabile, M; Ventruto, V	1
Curry, CJ; Froster-Iskenius, U; Hall, JG	1
Chodirker, BN; Chudley, AE; Ray, M; Riordan, DL; Wickstrom, DE	1
Fryns, JP; Petit, P	1
Higgins, S; Maltby, EL	1
Li, XZ; Yan, ZA; Zhou, XT	1
Das, BC; Juyal, RC; Rao, SR; Tewari, R; Thelma, BK	1
Dutrillaux, B; Muleris, M; Prieur, M	1
Sherman, SL; Sutherland, GR	1
Fryns, JP; Hecht, F; Petit, P; van den Berghe, H	1
Blomquist, HK; Dahlbom, K; Flood, A; Gustavson, KH; Holmgren, G; Sanner, G	1
Baker, E; Fratini, A; Sutherland, GR	1
Li, N; Zhou, XT	1

Reviews

9 review(s) available for folic acid and Chromosomal Fragility

Article	Year
Fragile sites and bladder cancer. Cancer genetics and cytogenetics, 2003, Jan-15, Volume: 140, Issue:2 Topics: Aphidicolin; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Chromosome Breakage; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Distamycins; Folic Acid; Humans; Urinary Bladder Neoplasms	2003
The molecular basis of common and rare fragile sites. Cancer letters, 2006, Jan-28, Volume: 232, Issue:1 Topics: Animals; Base Pairing; Base Sequence; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Disease Susceptibility; Folic Acid; Humans; Molecular Sequence Data	2006
Human chromosome fragility. Biochimica et biophysica acta, 2008, Volume: 1779, Issue:1 Topics: Base Sequence; Chromosome Fragile Sites; Chromosome Fragility; Cytogenetics; Distamycins; DNA; Female; Folic Acid; Fragile X Syndrome; Gene Expression; Humans; Male; Trinucleotide Repeat Expansion	2008
The fragile X chromosome: current methods. American journal of medical genetics, 1982, Volume: 11, Issue:4 Topics: Cells, Cultured; Chromosome Fragility; Chromosome Mapping; Female; Fibroblasts; Floxuridine; Folic Acid; Genetic Carrier Screening; Humans; Intellectual Disability; Lymphocytes; Male; Pregnancy; Prenatal Diagnosis; Sex Chromosome Aberrations; Sex Chromosomes; X Chromosome	1982
The fragile X syndrome: history, diagnosis, and treatment. Journal of developmental and behavioral pediatrics : JDBP, 1983, Volume: 4, Issue:2 Topics: Australia; Canada; Chromosome Fragile Sites; Chromosome Fragility; Folic Acid; Fragile X Syndrome; Genetic Markers; Heterozygote; History, 19th Century; History, 20th Century; Humans; Prenatal Diagnosis; Sex Chromosome Aberrations; United States	1983
Fragile X syndrome. Advances in pediatrics, 1994, Volume: 41 Topics: Adult; Base Sequence; Child; Chromosome Fragile Sites; Chromosome Fragility; Clinical Protocols; Connective Tissue Diseases; Diagnosis, Differential; DNA; Female; Folic Acid; Fragile X Syndrome; Gene Amplification; Genetic Linkage; Genetic Markers; Heterozygote; Humans; Male; Mental Disorders; Molecular Sequence Data; Mutation; Patient Education as Topic; Pedigree; Phenotype; Repetitive Sequences, Nucleic Acid; X Chromosome	1994
[Chromosomal fragile sites]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1996, Volume: 41, Issue:15 Suppl Topics: Animals; Chromosome Fragile Sites; Chromosome Fragility; DNA Methylation; Female; Folic Acid; Fragile X Syndrome; Genome, Human; Humans; Male; Mutation; Thymine; Trinucleotide Repeats	1996
Chromosomal fragile sites. Genetic analysis, techniques and applications, 1991, Volume: 8, Issue:6 Topics: Aphidicolin; Azacitidine; Blotting, Southern; Bromodeoxyuridine; Chromosome Fragile Sites; Chromosome Fragility; Folic Acid; Humans; Karyotyping; X Chromosome	1991
[Fragile X syndrome]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1990, Volume: 23, Issue:2 Topics: Chromosome Fragility; Folic Acid; Fragile X Syndrome; Humans; Sex Chromosome Aberrations	1990

Trials

2 trial(s) available for folic acid and Chromosomal Fragility

Article	Year
Folic acid therapy in the fragile X syndrome. American journal of medical genetics, 1984, Volume: 17, Issue:1 Topics: Adolescent; Child; Chromosome Fragility; Folic Acid; Fragile X Syndrome; Humans; Intelligence Tests; Male; Sex Chromosome Aberrations	1984
[Metabolism of monocarbons and the fragile X syndrome]. Bulletin de l'Academie nationale de medecine, 1981, Volume: 165, Issue:9 Topics: Adolescent; Adult; Child; Child, Preschool; Chromosome Fragility; Clinical Trials as Topic; Deanol; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Hydroxocobalamin; Intellectual Disability; Leucovorin; Male; Mental Disorders	1981

Other Studies

70 other study(ies) available for folic acid and Chromosomal Fragility

Article	Year
The expression of folate sensitive fragile sites in patients with bipolar disorder. Yonsei medical journal, 2009, Feb-28, Volume: 50, Issue:1 Topics: Adolescent; Adult; Bipolar Disorder; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Cytogenetics; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Young Adult	2009
Expression of folate sensitive and aphidicolin induced chromosomal fragile sites in familial neuroblastoma. Journal of experimental & clinical cancer research : CR, 2002, Volume: 21, Issue:3 Topics: Aphidicolin; Case-Control Studies; Cells, Cultured; Child, Preschool; Chromosome Aberrations; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 2; Enzyme Inhibitors; Female; Folic Acid; Genetic Predisposition to Disease; Hematinics; Humans; Infant; Karyotyping; Lymphocytes; Male; Neuroblastoma; Pedigree	2002
Cytogenetic investigations in mentally retarded and normal males from 14 families with the fragile site at Xq28. Results of folic acid treatment on fra(X) expression. Human genetics, 1984, Volume: 66, Issue:2-3 Topics: Adolescent; Adult; Bromodeoxyuridine; Cells, Cultured; Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Female; Fibroblasts; Floxuridine; Folic Acid; Gene Expression Regulation; Genetic Markers; Humans; Infant; Intellectual Disability; Lymphocytes; Male; Methotrexate; Middle Aged; X Chromosome	1984
Constitutive fragile sites and cancer. Science (New York, N.Y.), 1984, Dec-07, Volume: 226, Issue:4679 Topics: Adolescent; Adult; Animals; Caffeine; Cells, Cultured; Child; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Female; Floxuridine; Folic Acid; Gorilla gorilla; Humans; Male; Middle Aged; Neoplasms; Pan troglodytes; Thymidine	1984
[Autosomal fragile sites]. Journal de genetique humaine, 1984, Volume: 32, Issue:3 Topics: Adolescent; Adult; Bromodeoxyuridine; Child; Child, Preschool; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes; Chromosomes, Human, 6-12 and X; Distamycins; Female; Folic Acid; Humans; Infant; Infant, Newborn; Male; Phenotype; Thymidine	1984
Folate metabolism and chromosomal stability in the fragile X syndrome. The American journal of medicine, 1984, Volume: 77, Issue:4 Topics: Adult; Bone Marrow; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; DNA; Erythrocytes; Female; Fibroblasts; Folic Acid; Fragile X Syndrome; Humans; Karyotyping; Kinetics; Lymphocytes; Male; Pedigree; Sex Chromosome Aberrations; Sister Chromatid Exchange; Thymidine	1984
Folic acid and chromosome breakage. II. A methionine effect similar to that in fragile X expression. Human genetics, 1984, Volume: 68, Issue:2 Topics: Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Culture Media; Folic Acid; Fragile X Syndrome; Humans; Metaphase; Methionine	1984
On the nature of folic-acid-sensitive fragile sites in human chromosomes: an hypothesis. American journal of medical genetics, 1983, Volume: 16, Issue:1 Topics: Base Composition; Chromatin; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; DNA; Folic Acid; Humans; Methylation; Models, Biological; Nucleoproteins; Thymine; Uracil	1983
Folate, methionine, and the fragile X chromosome. American journal of human genetics, 1984, Volume: 36, Issue:2 Topics: Cells, Cultured; Chromosome Fragility; Folic Acid; Humans; Methionine	1984
Fragile sites in chromosomes: possible model for the study of spontaneous chromosome breakage. Science (New York, N.Y.), 1983, Apr-01, Volume: 220, Issue:4592 Topics: Adolescent; Adult; Cell Nucleus; Cells, Cultured; Child; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; Culture Media; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Lymphocytes; Male; Middle Aged; Thymidine	1983
A new inducible fragile site on chromosome 3(p14.2) in human lymphocytes. Human genetics, 1983, Volume: 63, Issue:3 Topics: Abnormalities, Multiple; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, 1-3; Female; Folic Acid; Humans; Infant, Newborn; Lymphocytes	1983
Heritable fragile sites on human chromosomes. X. New folate-sensitive fragile sites: 6p23, 9p21, 9q32, and 11q23. American journal of human genetics, 1983, Volume: 35, Issue:3 Topics: Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Chromosomes, Human, 6-12 and X; Culture Media; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Infant, Newborn; Karyotyping; Male; Pedigree; Thymidine	1983
Treatment of fragile-X. Pediatrics, 1982, Volume: 69, Issue:5 Topics: Adolescent; Adult; Chromosome Fragility; Female; Folic Acid; Humans; Intellectual Disability; Leucovorin; Male; Sex Chromosome Aberrations; Vitamin B 12	1982
Heritable fragile sites on human chromosomes. VIII. Preliminary population cytogenetic data on the folic-acid-sensitive fragile sites. American journal of human genetics, 1982, Volume: 34, Issue:3 Topics: Adolescent; Adult; Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, 6-12 and X; Female; Folic Acid; Heterozygote; Humans; Infant, Newborn; Intellectual Disability; Karyotyping; Male; Sex Chromosomes; X Chromosome	1982
Seckel syndrome in a family with three affected children and hematological manifestations associated with chromosome instability. Genetic counseling (Geneva, Switzerland), 1995, Volume: 6, Issue:1 Topics: Abnormalities, Multiple; Chromosome Aberrations; Chromosome Fragility; Dwarfism; Fatal Outcome; Female; Folic Acid; Hematologic Diseases; Humans; Infant, Newborn; Male; Sister Chromatid Exchange; Syndrome	1995
Molecular basis of p(CCG)n repeat instability at the FRA16A fragile site locus. Human molecular genetics, 1995, Volume: 4, Issue:3 Topics: Alleles; Asian People; Base Sequence; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Female; Folic Acid; Gene Frequency; Humans; Male; Models, Genetic; Molecular Sequence Data; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; White People	1995
Unusual behaviour of a human autosome having two rare folate sensitive fragile sites. Annales de genetique, 1993, Volume: 36, Issue:3 Topics: Adult; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 12; Female; Folic Acid; Gene Frequency; Humans; Karyotyping; Metaphase	1993
Folate sensitive common fragile sites in chromosomes of the domestic pig (Sus scrofa). Research in veterinary science, 1993, Volume: 55, Issue:2 Topics: Animals; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Female; Floxuridine; Folic Acid; Karyotyping; Lymphocytes; Male; Mitosis; Swine	1993
Identification of the FRAXE fragile site in two families ascertained for X linked mental retardation. Journal of medical genetics, 1993, Volume: 30, Issue:2 Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; DNA Mutational Analysis; DNA Probes; Folic Acid; Fragile X Syndrome; Genetic Linkage; Humans; In Situ Hybridization, Fluorescence; In Vitro Techniques; Male; Phenotype; Repetitive Sequences, Nucleic Acid; X Chromosome	1993
Folate-sensitive and aphidicolin-inducible fragile sites are expressed in the genome of the domestic cat. Cancer genetics and cytogenetics, 1993, Volume: 65, Issue:2 Topics: Animals; Aphidicolin; Caffeine; Cats; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Male; Trimethoprim	1993
Segregation analysis of rare autosomal folate sensitive fragile sites. American journal of medical genetics, 1993, Apr-15, Volume: 46, Issue:2 Topics: Autistic Disorder; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Female; Folic Acid; Genes, Dominant; Heterozygote; Humans; Intellectual Disability; Male; Pedigree; Sex Ratio	1993
Folic acid as a cancer-preventing agent. Medical hypotheses, 1995, Volume: 45, Issue:3 Topics: Animals; Anticarcinogenic Agents; Case-Control Studies; Chromosome Fragility; Cocarcinogenesis; Diet; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Global Health; Humans; Mice; Neoplasms; Neoplasms, Experimental; Prospective Studies; Rats; Vegetables	1995
Autosomal folate sensitive fragile sites in an autistic Basque sample. Annales de genetique, 1996, Volume: 39, Issue:2 Topics: Adolescent; Autistic Disorder; Case-Control Studies; Child; Chromosome Fragile Sites; Chromosome Fragility; Ethnicity; Female; Folic Acid; France; Humans; Male; Sex Characteristics	1996
Assignment of human KH-box-containing genes by in situ hybridization: HNRNPK maps to 9q21.32-q21.33, PCBP1 to 2p12-p13, and PCBP2 to 12q13.12-q13.13, distal to FRA12A. Genomics, 1996, Mar-01, Volume: 32, Issue:2 Topics: Chromosome Fragility; Chromosome Mapping; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 9; Folic Acid; Heterogeneous-Nuclear Ribonucleoproteins; Humans; In Situ Hybridization, Fluorescence; Ribonucleoproteins	1996
Mapping FRA11A, a folate-sensitive fragile site in human chromosome band 11q13.3. Cytogenetics and cell genetics, 1997, Volume: 79, Issue:1-2 Topics: Cells, Cultured; Centromere; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Chromosomes, Artificial, Yeast; Chromosomes, Human, Pair 11; Cosmids; Folic Acid; Hematinics; Humans; In Situ Hybridization, Fluorescence; Telomere	1997
Chromosomal fragile site expression in lymphocytes from patients with schizophrenia. Human genetics, 1998, Volume: 103, Issue:6 Topics: Adult; Asian People; Case-Control Studies; Cells, Cultured; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 9; Cohort Studies; Distamycins; Female; Folic Acid; Humans; Lymphocytes; Male; Schizophrenia; Taiwan	1998
Experience with direct molecular diagnosis of fragile X. Journal of medical genetics, 1992, Volume: 29, Issue:6 Topics: Artifacts; Chromosome Fragile Sites; Chromosome Fragility; DNA Probes; Female; Folic Acid; Fragile X Syndrome; Genetic Carrier Screening; Humans; Male; Pedigree	1992
Spontaneous and induced chromosome aberrations in Balkan endemic nephropathy. Kidney international. Supplement, 1991, Volume: 34 Topics: Balkan Nephropathy; Chromosome Aberrations; Chromosome Fragility; Chromosomes, Human, Pair 3; Folic Acid; Genetic Markers; Humans; In Vitro Techniques; Oncogenes	1991
A new folate sensitive fragile site at 1p21.3. Journal of medical genetics, 1991, Volume: 28, Issue:5 Topics: Abortion, Habitual; Adult; Aged; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 1; Female; Folic Acid; Humans; Lymphocytes; Pregnancy	1991
Chromosomal fragile site expression in dogs: I. Breed specific differences. American journal of medical genetics, 1991, Aug-01, Volume: 40, Issue:2 Topics: Aging; Animals; Aphidicolin; Breeding; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Culture Media; Diterpenes; Dogs; Female; Folic Acid; Genetic Variation; Lymphocytes; Male; Risk; Sex Factors; X Chromosome	1991
Chromosomal fragile site expression in dogs: II. Expression in boxer dogs with mast cell tumors. American journal of medical genetics, 1991, Aug-01, Volume: 40, Issue:2 Topics: Aging; Animals; Chromosome Fragile Sites; Chromosome Fragility; Cytogenetics; Disease Susceptibility; Dog Diseases; Dogs; Female; Folic Acid; Genetic Variation; Lymphocytes; Male; Mast-Cell Sarcoma; Risk; Tumor Cells, Cultured; X Chromosome	1991
A new apparently folate sensitive fragile site, 5q35. Journal of medical genetics, 1990, Volume: 27, Issue:8 Topics: Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 5; Folic Acid; Humans; Intellectual Disability; Male	1990
Neither age nor sex influence the expression of folate sensitive common fragile sites on human chromosomes. Human genetics, 1990, Volume: 86, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Humans; Infant; Lymphocytes; Male; Middle Aged; Sex Factors	1990
Possible association of rare autosomal folate sensitive fragile sites and idiopathic mental retardation: a blind controlled population study. Clinical genetics, 1990, Volume: 38, Issue:4 Topics: Abnormalities, Multiple; Adult; Chromosome Aberrations; Chromosome Disorders; Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Gene Frequency; Genetic Carrier Screening; Genetic Counseling; Genetic Testing; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Phenotype	1990
No difference in expression of chromosomal fragile sites in patients with solid malignant tumours and normal controls. Genes, chromosomes & cancer, 1990, Volume: 2, Issue:1 Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Folic Acid; Genetic Predisposition to Disease; Humans; Lymphocytes; Neoplasms; Single-Blind Method	1990
Folate-sensitive fragile sites in Chinese hamster cell lines. Cancer genetics and cytogenetics, 1990, Volume: 46, Issue:2 Topics: Animals; Cell Line; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Cricetinae; Cricetulus; Folic Acid; Karyotyping; Methotrexate	1990
Analysis of chromosome breakage in the Prader-Labhart-Willi syndrome. American journal of medical genetics, 1989, Volume: 32, Issue:4 Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Chromosome Deletion; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 15; Female; Folic Acid; Genetic Testing; Humans; Infant; Male; Mitomycin; Mitomycins; Prader-Willi Syndrome; Sister Chromatid Exchange	1989
Population cytogenetics of folate-sensitive fragile sites. II. Autosomal rare fragile sites. Human genetics, 1989, Volume: 82, Issue:1 Topics: Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Folic Acid; Gene Frequency; Genetics, Population; Humans; Intellectual Disability; Pedigree; Translocation, Genetic	1989
Increased chromosome fragility as a consequence of blood folate levels, smoking status, and coffee consumption. Environmental and molecular mutagenesis, 1989, Volume: 13, Issue:4 Topics: Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; Coffee; Drinking; Folic Acid; Humans; Sister Chromatid Exchange; Smoking	1989
Expression of folate-sensitive fragile sites in lymphocyte chromosomes. Human genetics, 1989, Volume: 81, Issue:3 Topics: Adult; Cells, Cultured; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Humans; Lymphocytes; Male; Methotrexate; X Chromosome	1989
Induction of fragile sites in fibroblasts. American journal of human genetics, 1986, Volume: 38, Issue:4 Topics: Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Female; Fibroblasts; Floxuridine; Folic Acid; Humans; Lymphocytes; Male	1986
Studies on three rare fragile sites. 2q13, 12q13, and 17p12 segregating in one family. Human genetics, 1986, Volume: 73, Issue:2 Topics: Adolescent; Aphidicolin; Cells, Cultured; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, 1-3; Chromosomes, Human, 16-18; Chromosomes, Human, 6-12 and X; Diterpenes; Female; Folic Acid; Humans; Karyotyping; Male; Pedigree; Sister Chromatid Exchange	1986
Breakpoint distribution in variant Philadelphia translocations in chronic myeloid leukemia. Nouvelle revue francaise d'hematologie, 1986, Volume: 28, Issue:5 Topics: Aphidicolin; Caffeine; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Diterpenes; Folic Acid; Humans; Leukemia, Myeloid; Oncogenes; Philadelphia Chromosome	1986
Folate- and deoxyuridine-sensitive chromatid breakage may result from DNA repair during G2. Mutation research, 1987, Volume: 192, Issue:3 Topics: Aphidicolin; Chromosome Aberrations; Chromosome Fragility; Cytarabine; Deoxyuridine; Diterpenes; DNA Repair; Folic Acid; Humans; In Vitro Techniques; Interphase; Lymphocytes; Uracil	1987
Common fragile sites induced by folate deprivation, BrdU and aphidicolin: their frequency and distribution in Japanese individuals. Jinrui idengaku zasshi. The Japanese journal of human genetics, 1988, Volume: 33, Issue:3 Topics: Adolescent; Adult; Aphidicolin; Bromodeoxyuridine; Child; Chromosome Fragile Sites; Chromosome Fragility; Diterpenes; Female; Folic Acid; Genetics, Population; Humans; In Vitro Techniques; Japan; Male	1988
A folate sensitive heritable fragile site at 19p13. Clinical genetics, 1985, Volume: 27, Issue:5 Topics: Adult; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Chromosomes, Human, 19-20; Down Syndrome; Female; Folic Acid; Humans; Infant, Newborn; Karyotyping; Lymphocytes; Pedigree	1985
Folic acid sensitive fragile sites are not limited to the human karyotype. Demonstration of nonrandom gaps and breaks in the Persian vole Ellobius lutescens Th. inducible by methotrexate, fluorodeoxyuridine, and aphidicolin. Human genetics, 1985, Volume: 70, Issue:2 Topics: Animals; Aphidicolin; Arvicolinae; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; Diterpenes; Female; Floxuridine; Folic Acid; Humans; Karyotyping; Male; Methotrexate; Species Specificity	1985
Synergistic effect of DAPI and thymidylate stress conditions on the induction of common fragile sites. Cytogenetics and cell genetics, 1988, Volume: 48, Issue:1 Topics: Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Culture Media; Female; Fluorescent Dyes; Folic Acid; Gene Expression Regulation; Humans; Indoles; Lymphocytes; Male; Thymidine	1988
Population cytogenetics of folate-sensitive fragile sites. I. Common fragile sites. Human genetics, 1988, Volume: 80, Issue:4 Topics: Child; Chromosome Fragile Sites; Chromosome Fragility; Folic Acid; Gene Frequency; Humans; Polymorphism, Genetic	1988
Effects of folate in culture medium on common fragile sites in lymphocyte chromosomes from normal and leukemic children. Human genetics, 1988, Volume: 81, Issue:1 Topics: Acute Disease; Adolescent; Cells, Cultured; Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Culture Media; Female; Folic Acid; Humans; Infant; Leukemia; Lymphocytes; Male	1988
Fragile site in chromosome 12 in a patient with two miscarriages. American journal of medical genetics, 1988, Volume: 31, Issue:3 Topics: Abortion, Habitual; Adult; Chromosome Aberrations; Chromosome Disorders; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 12; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Pregnancy	1988
Spontaneous expression of fra(10)(q25) in bone marrow from a patient with agranulocytosis. American journal of medical genetics, 1988, Volume: 31, Issue:3 Topics: Adult; Agranulocytosis; Bromodeoxyuridine; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 10; Female; Folic Acid; Hematopoietic Stem Cells; Humans; Karyotyping; Leukocytes; Time Factors	1988
Population cytogenetics of rare fragile sites in Japan. Human genetics, 1988, Volume: 78, Issue:2 Topics: Bromodeoxyuridine; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Distamycins; Female; Folic Acid; Gene Frequency; Genetic Variation; Humans; Japan; Karyotyping; Male	1988
Can sister chromatid intercrossings be considered as prelesions? Human genetics, 1988, Volume: 79, Issue:2 Topics: Cells, Cultured; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Folic Acid; Humans; Karyotyping; Lymphocytes; Methotrexate; Sister Chromatid Exchange	1988
Folate sensitive and BrdU dependent fragile sites on human chromosomes. Indian journal of experimental biology, 1988, Volume: 26, Issue:3 Topics: Bromodeoxyuridine; Chromosome Fragile Sites; Chromosome Fragility; Folic Acid; Humans	1988
Expression of the autosomal folate-sensitive fragile sites in ten kindreds with Martin-Bell syndrome. Annales de genetique, 1986, Volume: 29, Issue:1 Topics: Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Fragile X Syndrome; Humans; Intellectual Disability; Male; Phenotype; Sex Chromosome Aberrations	1986
False negative results in patients with fra(X) (q) mental retardation taking oral vitamin supplements. The New England journal of medicine, 1987, Apr-23, Volume: 316, Issue:17 Topics: Chromosome Fragility; False Negative Reactions; Folic Acid; Humans; Intellectual Disability; Male	1987
Fragile 19p13 in a family with mental illness. Clinical genetics, 1987, Volume: 31, Issue:1 Topics: Adult; Chromosome Aberrations; Chromosome Disorders; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, 19-20; Diseases in Twins; Folic Acid; Humans; Intellectual Disability; Male; Mental Disorders; Pedigree	1987
Population cytogenetics of autosomal fragile sites. Clinical genetics, 1987, Volume: 31, Issue:1 Topics: Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Humans; Intellectual Disability; Male	1987
Folate sensitive site at 10q23 and its expression as a deletion. Journal of medical genetics, 1987, Volume: 24, Issue:5 Topics: Chromosome Deletion; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 10; Folic Acid; Humans; Mosaicism	1987
The effect of 1-beta-D-arabinofuranosyl-cytosine on the expression of the common fragile site at 3p14. Human genetics, 1986, Volume: 74, Issue:4 Topics: Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 3; Cytarabine; DNA Repair; Female; Folic Acid; Gene Expression Regulation; Humans; Lymphocytes; Male	1986
Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. American journal of medical genetics, 1987, Volume: 26, Issue:1 Topics: Chromosome Fragile Sites; Chromosome Fragility; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Folic Acid; Humans; In Vitro Techniques; Lymphocytes	1987
Folate-sensitive fragile sites on the X-chromosome heterochromatin of the Indian mole rat, Nesokia indica. Cytogenetics and cell genetics, 1987, Volume: 44, Issue:1 Topics: Animals; Chromosome Fragile Sites; Chromosome Fragility; Folic Acid; Heterochromatin; Karyotyping; Muridae; X Chromosome	1987
[Exact localization of several fragile sites remains uncertain. The example of fra(10) sensitive to folate]. Annales de genetique, 1985, Volume: 28, Issue:3 Topics: Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, 6-12 and X; Folic Acid; Humans; Male	1985
Segregation analysis of rare autosomal fragile sites. Human genetics, 1986, Volume: 72, Issue:2 Topics: Bromodeoxyuridine; Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Humans; Male; Models, Genetic; Pedigree; Phenotype	1986
Population cytogenetics of autosomal fragile sites. Clinical genetics, 1986, Volume: 29, Issue:2 Topics: Chromosome Fragile Sites; Chromosome Fragility; Folic Acid; Intellectual Disability	1986
Effect of folic acid treatment in the fragile X syndrome. Clinical genetics, 1985, Volume: 27, Issue:5 Topics: Adolescent; Behavior; Child; Child, Preschool; Chromosome Fragility; Folic Acid; Fragile X Syndrome; Humans; Male; Middle Aged; Sex Chromosome Aberrations; Time Factors	1985
Excess thymidine induces folate sensitive fragile sites. American journal of medical genetics, 1985, Volume: 22, Issue:2 Topics: Base Sequence; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; DNA; Female; Folic Acid; Fragile X Syndrome; Humans; Lymphocytes; Male; Models, Genetic; Repetitive Sequences, Nucleic Acid; Thymidine	1985
Heritable fragile sites on human chromosomes. XII. Population cytogenetics. Annals of human genetics, 1985, Volume: 49, Issue:2 Topics: Adolescent; Adult; Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Female; Folic Acid; Humans; Infant; Infant, Newborn; Karyotyping; Male; Middle Aged; Polymorphism, Genetic; X Chromosome	1985
Human chromosome hot points. IV. Uridine-induced hot-point breaks at 3p14 and 16q23-24 and increased expression of fragile site Xq27 in folate-free medium. Human genetics, 1985, Volume: 71, Issue:4 Topics: Adult; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, 1-3; Chromosomes, Human, 16-18; Culture Media; Female; Folic Acid; Fragile X Syndrome; Humans; Karyotyping; Male; Pregnancy; Uridine; X Chromosome	1985