mitomycin has been researched along with Chromosomal Fragility in 16 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Induced chromosomal breakage study was successful in 171 out of 205 aplastic anemia (AA) patients." | 5.39 | Differentiation of Fanconi anemia and aplastic anemia using mitomycin C test in Tunisia. ( Abdelhak, S; Abidli, N; Aissaoui, L; Amouri, A; Ayed, W; Bejaoui, M; Ben Halim, N; Ben Othmane, T; Ben Romdhane, N; Ben Youssef, Y; Chemkhi, I; Elloumi, M; Guermani, H; Hadiji, S; Hentati, S; Kammoun, L; Kilani, O; Mellouli, F; Talmoudi, F; Torjmane, L, 2013) |
| "Analysis of chromosome breakage with mitomycin C (MMC) and folate-deficient culture conditions was undertaken on 18 Prader-Labhart-Willi syndrome (PLWS) patients (10 with 15q12 deletion [5 females, 5 males; mean age = 17." | 3.67 | Analysis of chromosome breakage in the Prader-Labhart-Willi syndrome. ( Butler, MG; Jenkins, BB, 1989) |
| "Induced chromosomal breakage study was successful in 171 out of 205 aplastic anemia (AA) patients." | 1.39 | Differentiation of Fanconi anemia and aplastic anemia using mitomycin C test in Tunisia. ( Abdelhak, S; Abidli, N; Aissaoui, L; Amouri, A; Ayed, W; Bejaoui, M; Ben Halim, N; Ben Othmane, T; Ben Romdhane, N; Ben Youssef, Y; Chemkhi, I; Elloumi, M; Guermani, H; Hadiji, S; Hentati, S; Kammoun, L; Kilani, O; Mellouli, F; Talmoudi, F; Torjmane, L, 2013) |
| "This entity of severe intrauterine growth retardation and increased mitomycin C sensitivity is hypothesised to be a distinct chromosome breakage syndrome." | 1.29 | Severe intrauterine growth retardation with increased mitomycin C sensitivity: a further chromosome breakage syndrome. ( Leversha, M; Rogers, JG; Woods, CG, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Talmoudi, F | 1 |
| Kilani, O | 1 |
| Ayed, W | 1 |
| Ben Halim, N | 1 |
| Mellouli, F | 1 |
| Torjmane, L | 1 |
| Aissaoui, L | 1 |
| Ben Youssef, Y | 1 |
| Kammoun, L | 1 |
| Ben Othmane, T | 1 |
| Bejaoui, M | 1 |
| Ben Romdhane, N | 1 |
| Elloumi, M | 1 |
| Hadiji, S | 1 |
| Hentati, S | 1 |
| Chemkhi, I | 1 |
| Abidli, N | 1 |
| Guermani, H | 1 |
| Abdelhak, S | 1 |
| Amouri, A | 1 |
| Chang, L | 1 |
| Yuan, W | 1 |
| Zeng, H | 1 |
| Zhou, Q | 1 |
| Wei, W | 1 |
| Zhou, J | 1 |
| Li, M | 1 |
| Wang, X | 1 |
| Xu, M | 1 |
| Yang, F | 1 |
| Yang, Y | 1 |
| Cheng, T | 1 |
| Zhu, X | 1 |
| Korgaonkar, S | 1 |
| Ghosh, K | 1 |
| Vundinti, BR | 1 |
| Castella, M | 1 |
| Pujol, R | 1 |
| Callén, E | 1 |
| Ramírez, MJ | 1 |
| Casado, JA | 1 |
| Talavera, M | 1 |
| Ferro, T | 1 |
| Muñoz, A | 1 |
| Sevilla, J | 1 |
| Madero, L | 1 |
| Cela, E | 1 |
| Beléndez, C | 1 |
| de Heredia, CD | 1 |
| Olivé, T | 1 |
| de Toledo, JS | 1 |
| Badell, I | 1 |
| Estella, J | 1 |
| Dasí, Á | 1 |
| Rodríguez-Villa, A | 1 |
| Gómez, P | 1 |
| Tapia, M | 1 |
| Molinés, A | 1 |
| Figuera, Á | 1 |
| Bueren, JA | 1 |
| Surrallés, J | 2 |
| Donoho, G | 1 |
| Brenneman, MA | 1 |
| Cui, TX | 1 |
| Donoviel, D | 1 |
| Vogel, H | 1 |
| Goodwin, EH | 1 |
| Chen, DJ | 1 |
| Hasty, P | 1 |
| Piñeiro, E | 1 |
| Fernàndez-López, L | 1 |
| Gamez, J | 1 |
| Marcos, R | 1 |
| Velázquez, A | 1 |
| Woods, CG | 1 |
| Leversha, M | 1 |
| Rogers, JG | 1 |
| Eldridge, MD | 1 |
| Johnston, PG | 1 |
| Wenger, SL | 2 |
| Bigatti, MP | 1 |
| Ardito, G | 1 |
| Lamberti, L | 1 |
| Crovella, S | 1 |
| Collell, M | 1 |
| Giordanino, S | 1 |
| Benso, L | 1 |
| Grant, SG | 1 |
| Latimer, JJ | 1 |
| Thull, D | 1 |
| Burke, LW | 1 |
| Butler, MG | 2 |
| Jenkins, BB | 1 |
| Bale, AE | 1 |
| Bale, SJ | 1 |
| Murli, H | 1 |
| Ivett, J | 1 |
| Mulvihill, JJ | 1 |
| Parry, DM | 1 |
| Hall, BD | 1 |
| Maclean, RN | 1 |
| Lozzio, CB | 1 |
| Tada, H | 1 |
| Ri, T | 1 |
| Yoshida, H | 1 |
| Ishimoto, K | 1 |
| Kaneko, M | 1 |
| Yamashiro, Y | 1 |
| Shinohara, T | 1 |
| Römke, C | 1 |
| Gödde-Salz, E | 1 |
| Grote, W | 1 |
16 other studies available for mitomycin and Chromosomal Fragility
| Article | Year |
|---|---|
Differentiation of Fanconi anemia and aplastic anemia using mitomycin C test in Tunisia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antibiotics, Antineoplastic; Child; Child, Preschool; Chromosom | 2013 |
Whole exome sequencing reveals concomitant mutations of multiple FA genes in individual Fanconi anemia patients.
Topics: Bone Marrow; Child; Child, Preschool; Chromosome Fragility; Comet Assay; DNA Mutational Analysis; Ex | 2014 |
Clinical, genetic and cytogenetic study of Fanconi anemia in an Indian population.
Topics: Adolescent; Carcinoma, Squamous Cell; Cells, Cultured; Child; Child, Preschool; Chromosome Breakage; | 2010 |
Chromosome fragility in patients with Fanconi anaemia: diagnostic implications and clinical impact.
Topics: Chromosome Fragility; Cross-Linking Reagents; Epoxy Compounds; Fanconi Anemia; Humans; Mitomycin; Mo | 2011 |
Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.
Topics: Animals; BRCA2 Protein; Breeding; Cell Line; Cell Line, Transformed; Cell Survival; Chromosome Fragi | 2003 |
Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1.
Topics: Alleles; Cells, Cultured; Chromosome Fragility; Humans; Mitomycin; Mutagenesis; Myotonic Dystrophy; | 2003 |
Severe intrauterine growth retardation with increased mitomycin C sensitivity: a further chromosome breakage syndrome.
Topics: Adult; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Chromosome Fragility; DNA Dama | 1995 |
Chromosomal rearrangements in rock wallabies, Petrogale (Marsupialia: Macropodidae). VIII. An investigation of the nonrandom nature of karyotypic change.
Topics: Animals; Biological Evolution; Chromosome Aberrations; Chromosome Banding; Chromosome Fragility; Chr | 1993 |
Chemical induction of sister chromatid exchange at fragile sites.
Topics: Aphidicolin; Caffeine; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Floxuridine; | 1995 |
Chromosomal aberrations, sister chromatid exchanges and high frequency cells in young patients with neurofibromatosis 1 (NF1).
Topics: Adolescent; Antimetabolites, Antineoplastic; Bleomycin; Child; Child, Preschool; Chromosome Aberrati | 2000 |
Analysis of genomic instability using multiple assays in a patient with Rothmund-Thomson syndrome.
Topics: Adult; Blood Group Antigens; Child; Child, Preschool; Chromosome Fragility; DNA Damage; DNA Repair; | 2000 |
Analysis of chromosome breakage in the Prader-Labhart-Willi syndrome.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Chromosome Deletion; Chromosome Fragile | 1989 |
Sister chromatid exchange and chromosome fragility in the nevoid basal cell carcinoma syndrome.
Topics: 4-Nitroquinoline-1-oxide; Adult; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Cells, Cultured; | 1989 |
Do some patients with Seckel syndrome have hematological problems and/or chromosome breakage?
Topics: Abnormalities, Multiple; Adolescent; Child; Chromosome Aberrations; Chromosome Fragility; Chromosome | 1987 |
A case of Shwachman syndrome with increased spontaneous chromosome breakage.
Topics: Bone Marrow Diseases; Chromosome Aberrations; Chromosome Fragility; Exocrine Pancreatic Insufficienc | 1987 |
Investigations of chromosomal stability in the Gorlin-Goltz syndrome.
Topics: Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Cells, Cultured; Chromosome Fragility; Chromosomes | 1985 |