trimethoprim has been researched along with Chromosomal Fragility in 4 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calva-Mercado, MP | 1 |
| Maunoury, C | 2 |
| Rethoré, MO | 2 |
| Lejeune, J | 2 |
| Legrand, N | 1 |
| Lafourcade, J | 1 |
| Raoul, O | 1 |
| Stone, DM | 1 |
| Stephens, KE | 1 |
| Doles, J | 1 |
| McLean, DA | 1 |
| Faed, MJ | 1 |
4 other studies available for trimethoprim and Chromosomal Fragility
| Article | Year |
|---|---|
[Fragility of the X chromosome and inhibition of dihydrofolate reductase. Comparison of the effects of 2 antibiotics: trimethoprim and pyrimethamine].
Topics: Adult; Child; Chromosome Fragility; Female; Folic Acid Antagonists; Humans; In Vitro Techniques; Mal | 1983 |
[X chromosome fragility and effects of trimethoprim].
Topics: Cells, Cultured; Child; Child, Preschool; Chromosome Fragility; Female; Humans; Lymphocytes; Male; M | 1982 |
Folate-sensitive and aphidicolin-inducible fragile sites are expressed in the genome of the domestic cat.
Topics: Animals; Aphidicolin; Caffeine; Cats; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragi | 1993 |
Improved fragile site detection with trimethoprim.
Topics: Chromosome Fragile Sites; Chromosome Fragility; Female; Fragile X Syndrome; Humans; Male; Sex Chromo | 1990 |