lipoxin a4 and 15-hydroxy-5,8,11,13-eicosatetraenoic acid

lipoxin a4 has been researched along with 15-hydroxy-5,8,11,13-eicosatetraenoic acid in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19906 (17.14)18.7374
1990's16 (45.71)18.2507
2000's12 (34.29)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chavis, C; Crastes de Paulet, A; Damon, M; Godard, P1
Badr, KF2
Högestätt, ED; Uski, TK1
Dahlén, SE; Hedqvist, P; Palmertz, U; Raud, J1
Anggård, A; Dahlén, B; Edenius, C; Kumlin, M; Lindgren, JA1
Manzini, S; Meini, S1
Kim, SJ1
Serhan, CN; Sheppard, KA1
Anggård, A; Björk, T; Edenius, C; Kumlin, M; Lindgren, JA1
Barbacane, RC; Bongrazio, M; Conti, P; Panara, MR; Piattelli, A; Reale, M; Trisi, P1
Roth, HJ; Steinhilber, D1
Serhan, CN1
Reardon, E; Serhan, CN1
Dahlén, SE; Marron, BE; Nicolaou, KC; Samuelsson, B; Serhan, CN; Veale, CA; Webber, SE1
Haeggström, J; Nicolaou, KC; Puustinen, TJ; Samuelsson, B; Serhan, CN; Veale, CA; Webber, SE1
Ng, J; Ramstedt, U; Samuelsson, B; Serhan, CN; Wigzell, H1
Chapman, HA; Drazen, J; Levy, BD; Reilly, JJ; Romano, M; Serhan, CN1
Chen, YQ; Honn, KV; Tang, DG1
Brady, HR; Hébert, MJ; Holthöfer, H; Takano, T1
Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E1
Denizot, Y; Desplat, V; Dulery, C; Praloran, V1
Elmqvist, A; Lindgren, JA; Tornhamre, S1
Denizot, Y; Godard, A; Praloran, V; Raher, S; Trimoreau, F1
Chiang, N; Clish, CB; Gronert, K; Levy, BD; Mastalerz, L; Sanak, M; Serhan, CN; Szczeklik, A1
Denizot, Y; Desplat, V; Dupuis, F; Faucher, JL; Ivanovic, Z; Praloran, V1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Godard, P; Vachier, I1
Berlasconi, G; Brady, HR; Cottell, DC; Godson, C; Maderna, P; Petasis, NA1
Bienkiewicz, B; DuBuske, L; Kowalski, ML; Pawliczak, R; Ptasinska, A1
Behbehani, B; Chan, L; Clish, C; Colgan, SP; Jain, A; Kantarci, A; Marleau, S; Merched, A; Petasis, NA; Serhan, CN; Stahl, GL; Van Dyke, TE1
Aliberti, J; Bannenberg, GL; Hong, S; Serhan, C; Sher, A1
Sakakibara, H; Yoneda, Y1
Bodzenta-Lukaszyk, A; Distler, O; Gay, RE; Gay, S; Kowal, K; Kowal-Bielecka, O; Michel, BA; Rojewska, J; Sierakowski, S1
Bleecker, ER; Busse, WW; Calhoun, WJ; Castro, M; Chung, KF; Curran-Everett, D; Erzurum, SC; Gaston, B; Haworth, O; Israel, E; Jarjour, NN; Kazani, S; Levy, BD; Mariani, TJ; Marigowda, G; Planagumà, A; Wenzel, SE1
Buret, AG; Duquette, SC; Feener, TD; Fischer, CD; Hollenberg, MD; Lucas, MJ; Morck, DW; Renaux, BS1

Reviews

3 review(s) available for lipoxin a4 and 15-hydroxy-5,8,11,13-eicosatetraenoic acid

ArticleYear
15-Lipoxygenase products as leukotriene antagonists: therapeutic potential in glomerulonephritis.
    Kidney international. Supplement, 1992, Volume: 38

    Topics: Animals; Arachidonate 15-Lipoxygenase; Glomerulonephritis; Humans; Hydroxyeicosatetraenoic Acids; Kidney Glomerulus; Leukotriene Antagonists; Leukotrienes; Lipoxins; SRS-A

1992
Lipoxygenases as therapeutic targets in the acute and subacute phases of glomerular immune injury.
    Contributions to nephrology, 1996, Volume: 118

    Topics: Animals; Glomerulonephritis; Humans; Hydroxyeicosatetraenoic Acids; Kidney Glomerulus; Leukotrienes; Lipoxins; Lipoxygenase; Macrophages; Neutrophils

1996
[Aspirin-induced asthma (AIA)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Dinoprostone; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxins; Mast Cells; Prostaglandin-Endoperoxide Synthases

2005

Other Studies

32 other study(ies) available for lipoxin a4 and 15-hydroxy-5,8,11,13-eicosatetraenoic acid

ArticleYear
Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells.
    Eicosanoids, 1992, Volume: 5, Issue:3-4

    Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lung; Macrophage Activation; Macrophages, Alveolar; Middle Aged

1992
Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries.
    General pharmacology, 1992, Volume: 23, Issue:1

    Topics: Animals; Basilar Artery; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Lipoxins; Lipoxygenase; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Vasoconstriction

1992
Lipoxins inhibit microvascular inflammatory actions of leukotriene B4.
    Advances in experimental medicine and biology, 1991, Volume: 314

    Topics: Animals; Cheek; Chemotaxis, Leukocyte; Cricetinae; Hydroxyeicosatetraenoic Acids; Inflammation; Leukocytes; Leukotriene B4; Lipoxins; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Muscle, Smooth, Vascular

1991
Conversion of leukotriene A4 to lipoxins by human nasal polyps and bronchial tissue.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate 15-Lipoxygenase; Bronchi; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Leukotrienes; Lipoxins; Nasal Polyps; Neutrophils

1991
Involvement of capsaicin-sensitive nerves in the bronchomotor effects of arachidonic acid and melittin: a possible role for lipoxin A4.
    British journal of pharmacology, 1991, Volume: 103, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzeneacetamides; Bronchi; Capsaicin; Epithelium; Guinea Pigs; Hydroxamic Acids; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Lipoxins; Lipoxygenase Inhibitors; Male; Melitten; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; SRS-A

1991
Elevated formation of lipoxins in viral antibody-positive rat alveolar macrophages.
    American journal of respiratory cell and molecular biology, 1990, Volume: 3, Issue:2

    Topics: Animals; Antibodies, Viral; Calcimycin; Chromatography, High Pressure Liquid; Hydroxyeicosatetraenoic Acids; Lipoxins; Macrophages; Male; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet

1990
Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:3

    Topics: Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Blood Platelets; Calcium; Cell Communication; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene A4; Leukotrienes; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stereoisomerism; Thrombin

1990
Lipoxin formation in human nasal polyps and bronchial tissue.
    FEBS letters, 1990, Oct-15, Volume: 272, Issue:1-2

    Topics: Arachidonate 15-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Bronchi; Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Leukotrienes; Lipoxins; Nasal Polyps; Neutrophils

1990
Lipoxins increase granuloma formation induced by potassium permanganate in vivo.
    Agents and actions, 1990, Volume: 29, Issue:1-2

    Topics: Animals; Drug Synergism; Granuloma; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Models, Biological; Potassium Permanganate; Rats; Rats, Inbred Strains

1990
New series of lipoxins isolated from human eosinophils.
    FEBS letters, 1989, Sep-11, Volume: 255, Issue:1

    Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Eosinophils; Granulocytes; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Spectrophotometry, Ultraviolet

1989
On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE.
    Biochimica et biophysica acta, 1989, Aug-08, Volume: 1004, Issue:2

    Topics: Calcimycin; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Leukotrienes; Lipoxins; Neutrophils; Spectrophotometry, Ultraviolet

1989
15-Hydroxyeicosatetraenoic acid inhibits superoxide anion generation by human neutrophils: relationship to lipoxin production.
    Free radical research communications, 1989, Volume: 7, Issue:3-6

    Topics: Calcimycin; Free Radicals; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxins; Neutrophils; Superoxides

1989
Identification of a novel 7-cis-11-trans-lipoxin A4 generated by human neutrophils: total synthesis, spasmogenic activities and comparison with other geometric isomers of lipoxins A4 and B4.
    Biochimica et biophysica acta, 1989, May-15, Volume: 1003, Issue:1

    Topics: Airway Resistance; Animals; Chemical Phenomena; Chemistry; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxins; Neutrophils; Stereoisomerism

1989
Stereochemistry and biosynthesis of lipoxins.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A

    Topics: Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukocytes; Lipoxins; Models, Chemical; Stereoisomerism

1987
Action of novel eicosanoids lipoxin A and B on human natural killer cell cytotoxicity: effects on intracellular cAMP and target cell binding.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:5

    Topics: Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Cytotoxicity, Immunologic; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Intracellular Fluid; Killer Cells, Natural; Leukemia, Erythroblastic, Acute; Lipoxins; Prostaglandins E

1985
Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:3

    Topics: Arachidonate 15-Lipoxygenase; Base Sequence; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-4; Leukotrienes; Lipoxins; Macrophages, Alveolar; Molecular Sequence Data; Oligodeoxyribonucleotides; RNA, Messenger

1993
Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Apoptosis; Arachidonate 12-Lipoxygenase; Base Sequence; Cell Division; Cell Line; Cell Survival; Female; Homeostasis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotriene C4; Leukotrienes; Lipid Peroxides; Lipoxins; Masoprocol; Molecular Sequence Data; Oligonucleotides, Antisense; Plasmids; Rats; Transfection

1996
Sequential morphologic events during apoptosis of human neutrophils. Modulation by lipoxygenase-derived eicosanoids.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Oct-01, Volume: 157, Issue:7

    Topics: Animals; Apoptosis; Cells, Cultured; Chromatin; DNA; Endothelium, Vascular; Flow Cytometry; Fluorescent Dyes; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lipoxygenase; Neutrophils; Rats; Receptors, Leukotriene B4; Signal Transduction

1996
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2

1999
Incorporation and effect of arachidonic acid on the growth of human myeloma cell lines.
    Mediators of inflammation, 1999, Volume: 8, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acylation; Arachidonic Acid; Cell Division; Cell Membrane; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxins; Lipoxygenase; Membrane Lipids; Multiple Myeloma; Phospholipids; Triglycerides; Tumor Cells, Cultured

1999
15-Lipoxygenation of leukotriene A(4). Studies Of 12- and 15-lipoxygenase efficiency to catalyze lipoxin formation.
    Biochimica et biophysica acta, 2000, Apr-12, Volume: 1484, Issue:2-3

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Blood Platelets; Enzyme Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene A4; Lipoxins; Rabbits; Reticulocytes; Swine

2000
Effect of cytokines and lipid mediators on the synthesis of interleukin 1 beta by human bone marrow stromal cells.
    Cytokine, 2000, Volume: 12, Issue:5

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Bone Marrow Cells; Cells, Cultured; Cytokines; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Leukotriene B4; Lipid Metabolism; Lipoxins; Platelet Activating Factor; Stromal Cells

2000
Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.
    The European respiratory journal, 2000, Volume: 16, Issue:1

    Topics: Adult; Aspirin; Asthma; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene C4; Lipoxins; Male; Middle Aged; Stereoisomerism

2000
Effects of lipoxygenase metabolites of arachidonic acid on the growth of human blood CD34(+) progenitors.
    Blood cells, molecules & diseases, 2000, Volume: 26, Issue:5

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Antigens, CD34; Antigens, Differentiation; Arachidonic Acids; Cell Count; Cell Division; Colony-Forming Units Assay; Culture Media; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Erythropoietin; Hematopoietic Stem Cells; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lipoxygenase; Methylcellulose; Solutions; Thymidine; Time Factors

2000
Endogenous anti-inflammatory mediators from arachidonate in human neutrophils.
    Biochemical and biophysical research communications, 2002, Jan-11, Volume: 290, Issue:1

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Neutrophils; Stereoisomerism

2002
Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: differential involvement of rho GTPases.
    The American journal of pathology, 2002, Volume: 160, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Eicosanoids; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Macrophages; Microscopy, Electron; Monocytes; Neutrophils; rac GTP-Binding Proteins; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Thionucleotides

2002
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients.
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dinoprostone; Drug Tolerance; Eicosanoids; Female; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ionophores; Leukocytes; Leukotriene C4; Lipoxins; Male; Middle Aged; Misoprostol

2003
Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Dec-15, Volume: 171, Issue:12

    Topics: Administration, Topical; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cell Degranulation; Cell Migration Inhibition; Eicosanoids; Esters; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Neutrophil Infiltration; Neutrophils; Periodontitis; Rabbits; Skin

2003
Exogenous pathogen and plant 15-lipoxygenase initiate endogenous lipoxin A4 biosynthesis.
    The Journal of experimental medicine, 2004, Feb-16, Volume: 199, Issue:4

    Topics: Animals; Arachidonate 15-Lipoxygenase; Enzyme-Linked Immunosorbent Assay; Glycine max; Hydroxyeicosatetraenoic Acids; Kinetics; Lipoxins; Proteome; Toxoplasma

2004
Cyclooxygenase- and lipoxygenase-derived eicosanoids in bronchoalveolar lavage fluid from patients with scleroderma lung disease: an imbalance between proinflammatory and antiinflammatory lipid mediators.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:12

    Topics: Adult; Aged; Bronchoalveolar Lavage Fluid; Dinoprostone; Eicosanoids; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lipoxygenase; Lung Diseases; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Scleroderma, Systemic

2005
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma.
    American journal of respiratory and critical care medicine, 2008, Sep-15, Volume: 178, Issue:6

    Topics: Adult; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Female; Flow Cytometry; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Middle Aged; Polymerase Chain Reaction; Receptors, Formyl Peptide; Receptors, Lipoxin

2008
Tulathromycin exerts proresolving effects in bovine neutrophils by inhibiting phospholipases and altering leukotriene B4, prostaglandin E2, and lipoxin A4 production.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Calcimycin; Cattle; Dinoprostone; Disaccharides; Heterocyclic Compounds; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lung; Male; Neutrophils; Particulate Matter; Phospholipases A2; Pneumonia; Primary Cell Culture; Zymosan

2014