lipoxin a4 and Asthma, Bronchial

lipoxin a4 has been researched along with Asthma, Bronchial in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (12.82)18.2507
2000's14 (35.90)29.6817
2010's18 (46.15)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Fedulov, AV; Ramar, M; Yano, N1
Kleniewska, P; Pawliczak, R; Szymczak-Pajor, I; Wieczfinska, J1
Chen, LC; Chiu, CY; Hua, MC; Huang, JL; Huang, SK; Kuo, ML; Lai, SH; Liao, SL; Su, KW; Tsai, MH; Tseng, HM; Wu, AH; Yao, TC; Yeh, KW1
Peebles, RS1
Bonini, M; Israel, E; Kazani, S; Levy, BD; Marigowda, G; Ono, E; Planaguma, A; Wechsler, ME; Zahid, M1
Barnig, C; Levy, BD2
Bae, DJ; Erle, DJ; Han, S; Jang, AS; Kim, D; Kim, HJ; Kim, YH; Lee, EH; Lee, EJ; Park, CS; Park, SW; Uh, ST1
Castro, M; Douda, DN; Dutile, S; Hammock, BD; Israel, E; Jarjour, NN; Kazani, S; Khaddaj-Mallat, R; Levy, BD; Martin, R; Ono, E; Rizcallah, E; Rousseau, E; Sirois, C; Sirois, M; Sutherland, ER; Tabet, Y; Wechsler, ME; Yang, J1
Chung, KF1
Chen, XQ; Kong, X; Wu, SH; Zhang, L1
Albano, GD; Anzalone, G; Bonanno, A; Chanez, P; Di Sano, C; Gagliardo, R; Gjomarkaj, M; Gras, D; La Grutta, S; Montalbano, AM; Profita, M; Riccobono, L; Vachier, I1
Calhoun, WJ; Kurosky, A; Maroto, R; Pazdrak, K; Stafford, S; Straub, C; White, WI1
Cernadas, M; Haworth, O; Levy, BD; Serhan, CN; Yang, R1
Bleecker, ER; Busse, WW; Calhoun, WJ; Castro, M; Chung, KF; Curran-Everett, D; Erzurum, SC; Gaston, B; Haworth, O; Israel, E; Jarjour, NN; Kazani, S; Levy, BD; Mariani, TJ; Marigowda, G; Planagumà, A; Wenzel, SE1
Billen, F; Cambier, C; Chandler, T; Clercx, C; Gustin, P; Kirschvink, N; Leemans, J1
Tao, HX; Wu, SH; Yin, PL; Zhang, YM1
Bhavsar, PK; Chung, KF; Hew, MJ; Israel, E; Kazani, S; Levy, BD; Pfeffer, MA1
Jiang, HM; Su, HP; Wu, HM; Wu, SH; Xu, D; Yao, WJ; Ye, XL; Yin, PL1
Ni, CM; Wan, KS; Yang, W1
Bonnans, C; Bourdin, A; Chanez, P; de Senneville, L; Gras, D; Vachier, I1
Arthur, GK; Bradding, P; Brightling, CE; Jones, DJ; Martin, N; Pavord, ID; Ruddick, A; Wan, H; Woodman, L1
Ackerman, K; De Sanctis, GT; Devchand, PR; Drazen, JM; Kim, E; Levy, BD; Schmidt, BA; Serhan, CN; Szczeklik, W1
Peters-Golden, M1
Bienkiewicz, B; DuBuske, L; Kowalski, ML; Pawliczak, R; Ptasinska, A1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Farce, M; Godard, P; Vachier, I1
Sakakibara, H; Yoneda, Y1
Bonnans, C; Israel, E; Levy, BD; Marigowda, G; Palmer, LJ; Silverman, ES1
Romano, M1
Celik, GE; Erkekol, FO; Melli, M; Misirligil, Z1
Hopkinson, P; Lipworth, BJ; Meldrum, KT; Menzies, D; Nair, A1
Gumus, H; Saraymen, R; Tahan, F1
Bertram, S; Drazen, JM; Fischer, A; Israel, E; Levy, BD; Serhan, CN; Tai, HH1
Drazen, JM; Levy, BD; Serhan, CN1
Rokach, J; Spokas, EG; Wong, PY1
Chiang, N; Clish, CB; Gronert, K; Levy, BD; Mastalerz, L; Sanak, M; Serhan, CN; Szczeklik, A1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Godard, P; Vachier, I1
Chavis, C; Crastes de Paulet, A; Damon, M; Godard, P1
Christie, PE; Lee, TH; Spur, BW1

Reviews

5 review(s) available for lipoxin a4 and Asthma, Bronchial

ArticleYear
A new horizon in asthma: inhibiting ILC function.
    Science translational medicine, 2013, Feb-27, Volume: 5, Issue:174

    Topics: Animals; Asthma; Humans; Lipoxins; Lymphocytes; Models, Immunological

2013
Innate immunity is a key factor for the resolution of inflammation in asthma.
    European respiratory review : an official journal of the European Respiratory Society, 2015, Volume: 24, Issue:135

    Topics: Asthma; Eosinophils; Humans; Immunity, Innate; Inflammation; Killer Cells, Natural; Lipoxins

2015
[Aspirin-induced asthma (AIA)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Dinoprostone; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxins; Mast Cells; Prostaglandin-Endoperoxide Synthases

2005
Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.
    Inflammation & allergy drug targets, 2006, Volume: 5, Issue:2

    Topics: Acetylation; Animals; Anti-Inflammatory Agents; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lipoxins; Periodontitis

2006
Leukotrienes, lipoxins, and hydroxyeicosatetraenoic acids.
    Methods in molecular biology (Clifton, N.J.), 1999, Volume: 120

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Asthma; Biological Transport; Cell Communication; Humans; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Kidney; Leukotrienes; Lipoxins; Lipoxygenase; Stereoisomerism

1999

Trials

3 trial(s) available for lipoxin a4 and Asthma, Bronchial

ArticleYear
Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.
    The Journal of allergy and clinical immunology, 2008, Volume: 121, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Breath Tests; Bronchial Provocation Tests; Double-Blind Method; Female; Humans; Inflammation; Lipoxins; Lung; Male; Nitric Oxide; Placebos; Respiratory Function Tests; Thromboxane B2

2008
Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA.
    Lipids, 1993, Volume: 28, Issue:12

    Topics: Adult; Aspirin; Asthma; Body Fluids; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Reproducibility of Results; Sensitivity and Specificity

1993
Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA.
    Advances in experimental medicine and biology, 1997, Volume: 400B

    Topics: Aspirin; Asthma; Blood Platelets; Cross-Over Studies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Neutrophils; Random Allocation; Recombinant Proteins

1997

Other Studies

31 other study(ies) available for lipoxin a4 and Asthma, Bronchial

ArticleYear
Intra-Airway Treatment with Synthetic Lipoxin A4 and Resolvin E2 Mitigates Neonatal Asthma Triggered by Maternal Exposure to Environmental Particles.
    International journal of molecular sciences, 2023, Mar-24, Volume: 24, Issue:7

    Topics: Animals; Asthma; Female; Humans; Infant, Newborn; Inflammation; Maternal Exposure; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Vehicle Emissions

2023
Wide-Range Effects of 1,25(OH)2D3 on Group 4A Phospholipases Is Related to Nuclear Factor κ-B and Phospholipase-A2 Activating Protein Activity in Mast Cells.
    International archives of allergy and immunology, 2020, Volume: 181, Issue:1

    Topics: Asthma; Cell Line, Transformed; Cholecalciferol; Gene Expression Regulation; Humans; Inflammation; Lipoxins; Mast Cells; NF-kappa B; Phospholipases A2; Signal Transduction; Ubiquitination

2020
A composite of exhaled LTB
    Allergy, 2018, Volume: 73, Issue:3

    Topics: Algorithms; Area Under Curve; Asthma; Biomarkers; Breath Tests; Child; Child, Preschool; Dinoprostone; Eicosanoids; Female; Forced Expiratory Volume; Humans; Leukotriene B4; Leukotriene E4; Lipoxins; Male; Nitric Oxide; ROC Curve; Sensitivity and Specificity

2018
Exhaled breath condensate eicosanoid levels associate with asthma and its severity.
    The Journal of allergy and clinical immunology, 2013, Volume: 132, Issue:3

    Topics: Adolescent; Adult; Asthma; Breath Tests; Exhalation; Female; Humans; Leukotriene B4; Lipoxins; Male; Middle Aged; Severity of Illness Index; Young Adult

2013
Lipoxin A4: a new direction in asthma therapy?
    Expert review of clinical immunology, 2013, Volume: 9, Issue:6

    Topics: Animals; Asthma; Humans; Inflammation; Lipoxins; Portraits as Topic; Respiratory System

2013
Apolipoprotein A1 potentiates lipoxin A4 synthesis and recovery of allergen-induced disrupted tight junctions in the airway epithelium.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2013, Volume: 43, Issue:8

    Topics: Allergens; Animals; Apolipoprotein A-I; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dendritic Cells; Humans; Lipoxins; Lung; Male; Mice; Pyroglyphidae; Respiratory Mucosa; Thymic Stromal Lymphopoietin; Tight Junctions

2013
Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma.
    American journal of respiratory and critical care medicine, 2014, Oct-15, Volume: 190, Issue:8

    Topics: Adult; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Epoxide Hydrolases; Female; Flow Cytometry; Humans; Lipoxins; Male; Middle Aged; Oxidative Stress; Severity of Illness Index; Sputum; Tumor Necrosis Factor-alpha

2014
Lipoxins and epoxyeicosatrienoic acids. Potential for inhibitors of soluble epoxide hydrolase in severe asthma?
    American journal of respiratory and critical care medicine, 2014, Oct-15, Volume: 190, Issue:8

    Topics: Asthma; Epoxide Hydrolases; Female; Humans; Lipoxins; Male; Oxidative Stress

2014
Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Gene Expression Regulation; Heptanoic Acids; Interleukin-1beta; Interleukin-4; Interleukin-6; Interleukin-8; Lipoxins; Male; Mice; Mice, Inbred BALB C; Myeloid Differentiation Factor 88; NF-kappa B; Ovalbumin; Receptors, Formyl Peptide; Signal Transduction; Toll-Like Receptor 2

2015
Airway lipoxin A4/formyl peptide receptor 2-lipoxin receptor levels in pediatric patients with severe asthma.
    The Journal of allergy and clinical immunology, 2016, Volume: 137, Issue:6

    Topics: Adrenal Cortex Hormones; Asthma; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Humans; Immunoglobulin E; Leukocytes; Leukotriene B4; Lipoxins; Male; Phosphorylation; Receptors, Formyl Peptide; Receptors, Glucocorticoid; Receptors, Lipoxin; Respiratory Function Tests; Severity of Illness Index; Signal Transduction; Skin Tests; Sputum

2016
Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 11-15, Volume: 197, Issue:10

    Topics: Apoptosis; Asthma; Cytokines; Dexamethasone; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypersensitivity; Interleukin-2; Interleukin-3; Interleukin-4; Interleukin-5; Lipoxins; Metabolism, Inborn Errors; Nuclear Proteins; Phosphoprotein Phosphatases; Phosphorylation; Proteomics; Receptors, Glucocorticoid; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha

2016
Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation.
    Nature immunology, 2008, Volume: 9, Issue:8

    Topics: Animals; Asthma; Disease Models, Animal; Eicosapentaenoic Acid; Inflammation; Inflammation Mediators; Interferon-gamma; Interleukin-23; Lipoxins; Lung; Mice

2008
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma.
    American journal of respiratory and critical care medicine, 2008, Sep-15, Volume: 178, Issue:6

    Topics: Adult; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Female; Flow Cytometry; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Middle Aged; Polymerase Chain Reaction; Receptors, Formyl Peptide; Receptors, Lipoxin

2008
Prophylactic effects of omega-3 polyunsaturated fatty acids and luteolin on airway hyperresponsiveness and inflammation in cats with experimentally-induced asthma.
    Veterinary journal (London, England : 1997), 2010, Volume: 184, Issue:1

    Topics: Animals; Ascaris suum; Asthma; Bronchoalveolar Lavage Fluid; Cat Diseases; Cats; Fatty Acids, Omega-3; Female; Inflammation; Lipoxins; Luteolin; Male

2010
Reversed changes of lipoxin A4 and leukotrienes in children with asthma in different severity degree.
    Pediatric pulmonology, 2010, Volume: 45, Issue:4

    Topics: Asthma; C-Reactive Protein; Child; Child, Preschool; Female; Humans; Immunoglobulin E; Interleukin-13; Interleukin-5; Interleukin-8; Leukotrienes; Lipoxins; Male; Respiratory Function Tests

2010
Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma.
    Respiratory research, 2010, Jun-07, Volume: 11

    Topics: Adrenal Cortex Hormones; Adult; Asthma; Bronchoscopy; Case-Control Studies; Dexamethasone; Down-Regulation; Female; Forced Expiratory Volume; Humans; Immunoenzyme Techniques; Inflammation Mediators; Leukotriene B4; Lipopolysaccharides; Lipoxins; Macrophages, Alveolar; Male; Middle Aged; Severity of Illness Index; Young Adult

2010
[Reversed changes of the 15-lipoxygenase product lipoxin A₄ and the 5-lipoxygenase product leukotriene C₄ in children with asthma].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2010, Volume: 33, Issue:7

    Topics: Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Asthma; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Leukocytes; Lipoxins; Male

2010
Serum levels of lipoxin A(4) do not predict the development of subsequent asthma among young children with acute bronchiolitis.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2011, Volume: 48, Issue:6

    Topics: Age Factors; Asthma; Biomarkers; Body Temperature; Bronchiolitis; Child; Child, Preschool; Dinoprostone; Eosinophil Cationic Protein; Female; Gastroenteritis; Humans; Immunoglobulin E; Infant; Interleukin-4; Interleukin-5; Leukocyte Count; Lipoxins; Male; Sex Characteristics; Tumor Necrosis Factor-alpha

2011
An ex vivo model of severe asthma using reconstituted human bronchial epithelium.
    The Journal of allergy and clinical immunology, 2012, Volume: 129, Issue:5

    Topics: Adult; Aged; Airway Remodeling; Asthma; Bronchi; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Disease Progression; Feasibility Studies; Female; Humans; Interleukin-8; Lipoxins; Lipoxygenase; Male; Middle Aged; Mucins; Respiratory Mucosa; Young Adult

2012
Primary human airway epithelial cell-dependent inhibition of human lung mast cell degranulation.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Asthma; Cell Degranulation; Cells, Cultured; Coculture Techniques; Docosahexaenoic Acids; Epithelial Cells; Histamine Release; Humans; Immunoglobulin E; Inflammation Mediators; Limit of Detection; Lipoxins; Lung; Mast Cells; Paracrine Communication; Pertussis Toxin; Receptors, Prostaglandin E, EP2 Subtype; Respiratory Mucosa; Xanthones

2012
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).
    Nature medicine, 2002, Volume: 8, Issue:9

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Chemokine CCL11; Chemokines, CC; Eosinophils; Hydroxyeicosatetraenoic Acids; Interleukin-13; Interleukin-5; Leukotrienes; Lipoxins; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Transgenic; Prostaglandins; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin

2002
'Good' lipids for asthma.
    Nature medicine, 2002, Volume: 8, Issue:9

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Mice; Mice, Transgenic; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin

2002
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients.
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dinoprostone; Drug Tolerance; Eicosanoids; Female; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ionophores; Leukocytes; Leukotriene C4; Lipoxins; Male; Middle Aged; Misoprostol

2003
Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound.
    The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:1

    Topics: Adult; Asthma; Female; Humans; Interleukin-8; Leukotriene B4; Lipoxins; Male; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sputum

2005
Diminished lipoxin biosynthesis in severe asthma.
    American journal of respiratory and critical care medicine, 2005, Oct-01, Volume: 172, Issue:7

    Topics: Adult; Asthma; Chromatography, High Pressure Liquid; Female; Forced Expiratory Volume; Humans; Lipoxins; Male; Membrane Proteins; Receptors, Leukotriene; Sputum

2005
Lipoxin A4 levels in asthma: relation with disease severity and aspirin sensitivity.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:10

    Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Lipoxins; Male; Middle Aged; Severity of Illness Index

2007
The role of lipoxin A4 in exercise-induced bronchoconstriction in asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2008, Volume: 45, Issue:2

    Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Child; Enzyme-Linked Immunosorbent Assay; Exercise Test; Female; Humans; Lipoxins; Male

2008
Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.
    The European respiratory journal, 2000, Volume: 16, Issue:1

    Topics: Adult; Aspirin; Asthma; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene C4; Lipoxins; Male; Middle Aged; Stereoisomerism

2000
Lipoxins are potential endogenous antiinflammatory mediators in asthma.
    American journal of respiratory and critical care medicine, 2002, Jun-01, Volume: 165, Issue:11

    Topics: Asthma; Base Sequence; Biomarkers; Bronchial Provocation Tests; Female; Humans; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Interleukin-8; Lipoxins; Male; Molecular Sequence Data; Probability; Prospective Studies; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sampling Studies; Sensitivity and Specificity; Severity of Illness Index; Sputum; Statistics, Nonparametric

2002
Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells.
    Eicosanoids, 1992, Volume: 5, Issue:3-4

    Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lung; Macrophage Activation; Macrophages, Alveolar; Middle Aged

1992
The effects of lipoxin A4 on airway responses in asthmatic subjects.
    The American review of respiratory disease, 1992, Volume: 145, Issue:6

    Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; SRS-A

1992