lipoxin a4 and Asthma

lipoxin a4 has been researched along with Asthma in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (12.82)18.2507
2000's14 (35.90)29.6817
2010's18 (46.15)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Fedulov, AV; Ramar, M; Yano, N1
Kleniewska, P; Pawliczak, R; Szymczak-Pajor, I; Wieczfinska, J1
Chen, LC; Chiu, CY; Hua, MC; Huang, JL; Huang, SK; Kuo, ML; Lai, SH; Liao, SL; Su, KW; Tsai, MH; Tseng, HM; Wu, AH; Yao, TC; Yeh, KW1
Peebles, RS1
Bonini, M; Israel, E; Kazani, S; Levy, BD; Marigowda, G; Ono, E; Planaguma, A; Wechsler, ME; Zahid, M1
Barnig, C; Levy, BD2
Bae, DJ; Erle, DJ; Han, S; Jang, AS; Kim, D; Kim, HJ; Kim, YH; Lee, EH; Lee, EJ; Park, CS; Park, SW; Uh, ST1
Castro, M; Douda, DN; Dutile, S; Hammock, BD; Israel, E; Jarjour, NN; Kazani, S; Khaddaj-Mallat, R; Levy, BD; Martin, R; Ono, E; Rizcallah, E; Rousseau, E; Sirois, C; Sirois, M; Sutherland, ER; Tabet, Y; Wechsler, ME; Yang, J1
Chung, KF1
Chen, XQ; Kong, X; Wu, SH; Zhang, L1
Albano, GD; Anzalone, G; Bonanno, A; Chanez, P; Di Sano, C; Gagliardo, R; Gjomarkaj, M; Gras, D; La Grutta, S; Montalbano, AM; Profita, M; Riccobono, L; Vachier, I1
Calhoun, WJ; Kurosky, A; Maroto, R; Pazdrak, K; Stafford, S; Straub, C; White, WI1
Cernadas, M; Haworth, O; Levy, BD; Serhan, CN; Yang, R1
Bleecker, ER; Busse, WW; Calhoun, WJ; Castro, M; Chung, KF; Curran-Everett, D; Erzurum, SC; Gaston, B; Haworth, O; Israel, E; Jarjour, NN; Kazani, S; Levy, BD; Mariani, TJ; Marigowda, G; Planagumà, A; Wenzel, SE1
Billen, F; Cambier, C; Chandler, T; Clercx, C; Gustin, P; Kirschvink, N; Leemans, J1
Tao, HX; Wu, SH; Yin, PL; Zhang, YM1
Bhavsar, PK; Chung, KF; Hew, MJ; Israel, E; Kazani, S; Levy, BD; Pfeffer, MA1
Jiang, HM; Su, HP; Wu, HM; Wu, SH; Xu, D; Yao, WJ; Ye, XL; Yin, PL1
Ni, CM; Wan, KS; Yang, W1
Bonnans, C; Bourdin, A; Chanez, P; de Senneville, L; Gras, D; Vachier, I1
Arthur, GK; Bradding, P; Brightling, CE; Jones, DJ; Martin, N; Pavord, ID; Ruddick, A; Wan, H; Woodman, L1
Ackerman, K; De Sanctis, GT; Devchand, PR; Drazen, JM; Kim, E; Levy, BD; Schmidt, BA; Serhan, CN; Szczeklik, W1
Peters-Golden, M1
Bienkiewicz, B; DuBuske, L; Kowalski, ML; Pawliczak, R; Ptasinska, A1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Farce, M; Godard, P; Vachier, I1
Sakakibara, H; Yoneda, Y1
Bonnans, C; Israel, E; Levy, BD; Marigowda, G; Palmer, LJ; Silverman, ES1
Romano, M1
Celik, GE; Erkekol, FO; Melli, M; Misirligil, Z1
Hopkinson, P; Lipworth, BJ; Meldrum, KT; Menzies, D; Nair, A1
Gumus, H; Saraymen, R; Tahan, F1
Bertram, S; Drazen, JM; Fischer, A; Israel, E; Levy, BD; Serhan, CN; Tai, HH1
Drazen, JM; Levy, BD; Serhan, CN1
Rokach, J; Spokas, EG; Wong, PY1
Chiang, N; Clish, CB; Gronert, K; Levy, BD; Mastalerz, L; Sanak, M; Serhan, CN; Szczeklik, A1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Godard, P; Vachier, I1
Chavis, C; Crastes de Paulet, A; Damon, M; Godard, P1
Christie, PE; Lee, TH; Spur, BW1

Reviews

5 review(s) available for lipoxin a4 and Asthma

ArticleYear
A new horizon in asthma: inhibiting ILC function.
    Science translational medicine, 2013, Feb-27, Volume: 5, Issue:174

    Topics: Animals; Asthma; Humans; Lipoxins; Lymphocytes; Models, Immunological

2013
Innate immunity is a key factor for the resolution of inflammation in asthma.
    European respiratory review : an official journal of the European Respiratory Society, 2015, Volume: 24, Issue:135

    Topics: Asthma; Eosinophils; Humans; Immunity, Innate; Inflammation; Killer Cells, Natural; Lipoxins

2015
[Aspirin-induced asthma (AIA)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Dinoprostone; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxins; Mast Cells; Prostaglandin-Endoperoxide Synthases

2005
Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.
    Inflammation & allergy drug targets, 2006, Volume: 5, Issue:2

    Topics: Acetylation; Animals; Anti-Inflammatory Agents; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lipoxins; Periodontitis

2006
Leukotrienes, lipoxins, and hydroxyeicosatetraenoic acids.
    Methods in molecular biology (Clifton, N.J.), 1999, Volume: 120

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Asthma; Biological Transport; Cell Communication; Humans; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Kidney; Leukotrienes; Lipoxins; Lipoxygenase; Stereoisomerism

1999

Trials

3 trial(s) available for lipoxin a4 and Asthma

ArticleYear
Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.
    The Journal of allergy and clinical immunology, 2008, Volume: 121, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Breath Tests; Bronchial Provocation Tests; Double-Blind Method; Female; Humans; Inflammation; Lipoxins; Lung; Male; Nitric Oxide; Placebos; Respiratory Function Tests; Thromboxane B2

2008
Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA.
    Lipids, 1993, Volume: 28, Issue:12

    Topics: Adult; Aspirin; Asthma; Body Fluids; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Reproducibility of Results; Sensitivity and Specificity

1993
Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA.
    Advances in experimental medicine and biology, 1997, Volume: 400B

    Topics: Aspirin; Asthma; Blood Platelets; Cross-Over Studies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Neutrophils; Random Allocation; Recombinant Proteins

1997

Other Studies

31 other study(ies) available for lipoxin a4 and Asthma

ArticleYear
Intra-Airway Treatment with Synthetic Lipoxin A4 and Resolvin E2 Mitigates Neonatal Asthma Triggered by Maternal Exposure to Environmental Particles.
    International journal of molecular sciences, 2023, Mar-24, Volume: 24, Issue:7

    Topics: Animals; Asthma; Female; Humans; Infant, Newborn; Inflammation; Maternal Exposure; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Vehicle Emissions

2023
Wide-Range Effects of 1,25(OH)2D3 on Group 4A Phospholipases Is Related to Nuclear Factor κ-B and Phospholipase-A2 Activating Protein Activity in Mast Cells.
    International archives of allergy and immunology, 2020, Volume: 181, Issue:1

    Topics: Asthma; Cell Line, Transformed; Cholecalciferol; Gene Expression Regulation; Humans; Inflammation; Lipoxins; Mast Cells; NF-kappa B; Phospholipases A2; Signal Transduction; Ubiquitination

2020
A composite of exhaled LTB
    Allergy, 2018, Volume: 73, Issue:3

    Topics: Algorithms; Area Under Curve; Asthma; Biomarkers; Breath Tests; Child; Child, Preschool; Dinoprostone; Eicosanoids; Female; Forced Expiratory Volume; Humans; Leukotriene B4; Leukotriene E4; Lipoxins; Male; Nitric Oxide; ROC Curve; Sensitivity and Specificity

2018
Exhaled breath condensate eicosanoid levels associate with asthma and its severity.
    The Journal of allergy and clinical immunology, 2013, Volume: 132, Issue:3

    Topics: Adolescent; Adult; Asthma; Breath Tests; Exhalation; Female; Humans; Leukotriene B4; Lipoxins; Male; Middle Aged; Severity of Illness Index; Young Adult

2013
Lipoxin A4: a new direction in asthma therapy?
    Expert review of clinical immunology, 2013, Volume: 9, Issue:6

    Topics: Animals; Asthma; Humans; Inflammation; Lipoxins; Portraits as Topic; Respiratory System

2013
Apolipoprotein A1 potentiates lipoxin A4 synthesis and recovery of allergen-induced disrupted tight junctions in the airway epithelium.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2013, Volume: 43, Issue:8

    Topics: Allergens; Animals; Apolipoprotein A-I; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dendritic Cells; Humans; Lipoxins; Lung; Male; Mice; Pyroglyphidae; Respiratory Mucosa; Thymic Stromal Lymphopoietin; Tight Junctions

2013
Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma.
    American journal of respiratory and critical care medicine, 2014, Oct-15, Volume: 190, Issue:8

    Topics: Adult; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Epoxide Hydrolases; Female; Flow Cytometry; Humans; Lipoxins; Male; Middle Aged; Oxidative Stress; Severity of Illness Index; Sputum; Tumor Necrosis Factor-alpha

2014
Lipoxins and epoxyeicosatrienoic acids. Potential for inhibitors of soluble epoxide hydrolase in severe asthma?
    American journal of respiratory and critical care medicine, 2014, Oct-15, Volume: 190, Issue:8

    Topics: Asthma; Epoxide Hydrolases; Female; Humans; Lipoxins; Male; Oxidative Stress

2014
Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Gene Expression Regulation; Heptanoic Acids; Interleukin-1beta; Interleukin-4; Interleukin-6; Interleukin-8; Lipoxins; Male; Mice; Mice, Inbred BALB C; Myeloid Differentiation Factor 88; NF-kappa B; Ovalbumin; Receptors, Formyl Peptide; Signal Transduction; Toll-Like Receptor 2

2015
Airway lipoxin A4/formyl peptide receptor 2-lipoxin receptor levels in pediatric patients with severe asthma.
    The Journal of allergy and clinical immunology, 2016, Volume: 137, Issue:6

    Topics: Adrenal Cortex Hormones; Asthma; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Humans; Immunoglobulin E; Leukocytes; Leukotriene B4; Lipoxins; Male; Phosphorylation; Receptors, Formyl Peptide; Receptors, Glucocorticoid; Receptors, Lipoxin; Respiratory Function Tests; Severity of Illness Index; Signal Transduction; Skin Tests; Sputum

2016
Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 11-15, Volume: 197, Issue:10

    Topics: Apoptosis; Asthma; Cytokines; Dexamethasone; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypersensitivity; Interleukin-2; Interleukin-3; Interleukin-4; Interleukin-5; Lipoxins; Metabolism, Inborn Errors; Nuclear Proteins; Phosphoprotein Phosphatases; Phosphorylation; Proteomics; Receptors, Glucocorticoid; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha

2016
Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation.
    Nature immunology, 2008, Volume: 9, Issue:8

    Topics: Animals; Asthma; Disease Models, Animal; Eicosapentaenoic Acid; Inflammation; Inflammation Mediators; Interferon-gamma; Interleukin-23; Lipoxins; Lung; Mice

2008
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma.
    American journal of respiratory and critical care medicine, 2008, Sep-15, Volume: 178, Issue:6

    Topics: Adult; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Female; Flow Cytometry; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Middle Aged; Polymerase Chain Reaction; Receptors, Formyl Peptide; Receptors, Lipoxin

2008
Prophylactic effects of omega-3 polyunsaturated fatty acids and luteolin on airway hyperresponsiveness and inflammation in cats with experimentally-induced asthma.
    Veterinary journal (London, England : 1997), 2010, Volume: 184, Issue:1

    Topics: Animals; Ascaris suum; Asthma; Bronchoalveolar Lavage Fluid; Cat Diseases; Cats; Fatty Acids, Omega-3; Female; Inflammation; Lipoxins; Luteolin; Male

2010
Reversed changes of lipoxin A4 and leukotrienes in children with asthma in different severity degree.
    Pediatric pulmonology, 2010, Volume: 45, Issue:4

    Topics: Asthma; C-Reactive Protein; Child; Child, Preschool; Female; Humans; Immunoglobulin E; Interleukin-13; Interleukin-5; Interleukin-8; Leukotrienes; Lipoxins; Male; Respiratory Function Tests

2010
Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma.
    Respiratory research, 2010, Jun-07, Volume: 11

    Topics: Adrenal Cortex Hormones; Adult; Asthma; Bronchoscopy; Case-Control Studies; Dexamethasone; Down-Regulation; Female; Forced Expiratory Volume; Humans; Immunoenzyme Techniques; Inflammation Mediators; Leukotriene B4; Lipopolysaccharides; Lipoxins; Macrophages, Alveolar; Male; Middle Aged; Severity of Illness Index; Young Adult

2010
[Reversed changes of the 15-lipoxygenase product lipoxin A₄ and the 5-lipoxygenase product leukotriene C₄ in children with asthma].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2010, Volume: 33, Issue:7

    Topics: Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Asthma; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Leukocytes; Lipoxins; Male

2010
Serum levels of lipoxin A(4) do not predict the development of subsequent asthma among young children with acute bronchiolitis.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2011, Volume: 48, Issue:6

    Topics: Age Factors; Asthma; Biomarkers; Body Temperature; Bronchiolitis; Child; Child, Preschool; Dinoprostone; Eosinophil Cationic Protein; Female; Gastroenteritis; Humans; Immunoglobulin E; Infant; Interleukin-4; Interleukin-5; Leukocyte Count; Lipoxins; Male; Sex Characteristics; Tumor Necrosis Factor-alpha

2011
An ex vivo model of severe asthma using reconstituted human bronchial epithelium.
    The Journal of allergy and clinical immunology, 2012, Volume: 129, Issue:5

    Topics: Adult; Aged; Airway Remodeling; Asthma; Bronchi; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Disease Progression; Feasibility Studies; Female; Humans; Interleukin-8; Lipoxins; Lipoxygenase; Male; Middle Aged; Mucins; Respiratory Mucosa; Young Adult

2012
Primary human airway epithelial cell-dependent inhibition of human lung mast cell degranulation.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Asthma; Cell Degranulation; Cells, Cultured; Coculture Techniques; Docosahexaenoic Acids; Epithelial Cells; Histamine Release; Humans; Immunoglobulin E; Inflammation Mediators; Limit of Detection; Lipoxins; Lung; Mast Cells; Paracrine Communication; Pertussis Toxin; Receptors, Prostaglandin E, EP2 Subtype; Respiratory Mucosa; Xanthones

2012
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).
    Nature medicine, 2002, Volume: 8, Issue:9

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Chemokine CCL11; Chemokines, CC; Eosinophils; Hydroxyeicosatetraenoic Acids; Interleukin-13; Interleukin-5; Leukotrienes; Lipoxins; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Transgenic; Prostaglandins; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin

2002
'Good' lipids for asthma.
    Nature medicine, 2002, Volume: 8, Issue:9

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Mice; Mice, Transgenic; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin

2002
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients.
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dinoprostone; Drug Tolerance; Eicosanoids; Female; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ionophores; Leukocytes; Leukotriene C4; Lipoxins; Male; Middle Aged; Misoprostol

2003
Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound.
    The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:1

    Topics: Adult; Asthma; Female; Humans; Interleukin-8; Leukotriene B4; Lipoxins; Male; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sputum

2005
Diminished lipoxin biosynthesis in severe asthma.
    American journal of respiratory and critical care medicine, 2005, Oct-01, Volume: 172, Issue:7

    Topics: Adult; Asthma; Chromatography, High Pressure Liquid; Female; Forced Expiratory Volume; Humans; Lipoxins; Male; Membrane Proteins; Receptors, Leukotriene; Sputum

2005
Lipoxin A4 levels in asthma: relation with disease severity and aspirin sensitivity.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:10

    Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Lipoxins; Male; Middle Aged; Severity of Illness Index

2007
The role of lipoxin A4 in exercise-induced bronchoconstriction in asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2008, Volume: 45, Issue:2

    Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Child; Enzyme-Linked Immunosorbent Assay; Exercise Test; Female; Humans; Lipoxins; Male

2008
Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.
    The European respiratory journal, 2000, Volume: 16, Issue:1

    Topics: Adult; Aspirin; Asthma; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene C4; Lipoxins; Male; Middle Aged; Stereoisomerism

2000
Lipoxins are potential endogenous antiinflammatory mediators in asthma.
    American journal of respiratory and critical care medicine, 2002, Jun-01, Volume: 165, Issue:11

    Topics: Asthma; Base Sequence; Biomarkers; Bronchial Provocation Tests; Female; Humans; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Interleukin-8; Lipoxins; Male; Molecular Sequence Data; Probability; Prospective Studies; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sampling Studies; Sensitivity and Specificity; Severity of Illness Index; Sputum; Statistics, Nonparametric

2002
Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells.
    Eicosanoids, 1992, Volume: 5, Issue:3-4

    Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lung; Macrophage Activation; Macrophages, Alveolar; Middle Aged

1992
The effects of lipoxin A4 on airway responses in asthmatic subjects.
    The American review of respiratory disease, 1992, Volume: 145, Issue:6

    Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; SRS-A

1992