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ChEBI ID: 48433
Member | Definition | Role |
---|---|---|
angiotensin i | A nine amino acid peptide which is formed when angiotensin converting enzyme 2 (ACE2) hydrolyzes the carboxy terminal leucine from angiotensin I. It is a anti-cardiac hypertrophy agent. | angiotensin (1-9) dizwitterion; angiotensin (1-9) |
angiotensin i | A ten amino acid peptide formed by renin cleavage of angiotensinogen. Angiotensin I has no direct biological function except that high levels can stimulate catecholamine production. It is metabolized to its biologically active byproduct angiotensin II, a potent vasoconstrictor, by angiotensin converting enzyme (ACE) through cleavage of the two terminal amino acids. | angiotensin I dizwitterion; angiotensin I |
angiotensin i, ile(5)- | A ten amino acid peptide formed by renin cleavage of angiotensinogen. Angiotensin I has no direct biological function except that high levels can stimulate catecholamine production. It is metabolized to its biologically active byproduct angiotensin II, a potent vasoconstrictor, by angiotensin converting enzyme (ACE) through cleavage of the two terminal amino acids. | angiotensin I dizwitterion; angiotensin I |
angiotensin ii, des-phe(8)- | An angiotensin compound consisting of the linear heptapeptide sequence L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro. | Ile(5)-angiotensin II (1-7) dizwitterion; Ile(5)-angiotensin II (1-7) |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 906 (22.29) | 18.7374 |
1990's | 946 (23.27) | 18.2507 |
2000's | 844 (20.76) | 29.6817 |
2010's | 1,064 (26.17) | 24.3611 |
2020's | 305 (7.50) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 146 (2.52%) | 5.53% |
Reviews | 595 (10.28%) | 6.00% |
Case Studies | 22 (0.38%) | 4.05% |
Observational | 8 (0.14%) | 0.25% |
Other | 5,015 (86.67%) | 84.16% |