Mono-hydroperoxy (e)icosatetraenoic acids (HPETEs) are the primary products of lipoxygenase-catalysed oxygenation of arachidonic acid.
ChEBI ID: 24644
| Member | Definition | Role |
|---|---|---|
| 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid | A HPETE that consists of (5Z,8Z,11Z,13E)-icosatetraenoic acid in which the hydroperoxy group is located at position 15. | 15-HPETE |
| arachidonic acid 5-hydroperoxide | A HPETE that consists of (6E,8Z,11Z,14Z)-icosatetraenoic acid in which the hydroperoxy group is located at position 5. | 5-HPETE |
| arachidonic acid omega-9 hydroperoxide | The (S)-enantiomer of 12-HPETE. | 12(S)-HPETE |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 266 (50.38) | 18.7374 |
| 1990's | 161 (30.49) | 18.2507 |
| 2000's | 75 (14.20) | 29.6817 |
| 2010's | 20 (3.79) | 24.3611 |
| 2020's | 6 (1.14) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 34 (5.70%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 562 (94.30%) | 84.16% |