lipoxin a4 and leukotriene b4

lipoxin a4 has been researched along with leukotriene b4 in 90 studies

Research

Studies (90)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (11.11)	18.7374
1990's	28 (31.11)	18.2507
2000's	25 (27.78)	29.6817
2010's	23 (25.56)	24.3611
2020's	4 (4.44)	2.80

Authors

Authors	Studies
Fiore, S; Ryeom, SW; Serhan, CN; Weller, PF	1
Pettitt, TR; Rowley, AF; Secombes, CJ; Sharp, GJ	1
Chavis, C; Crastes de Paulet, A; Damon, M; Godard, P	1
Barbacane, RC; Bongrazio, M; Conti, P; Panara, MR; Reale, M	2
Crea, AE; Lee, TH; Lympany, P; Spur, BW	1
Dahlén, SE; Hedqvist, P; Palmertz, U; Raud, J	1
Garrick, R; Wong, PY	1
Garrick, R; Goodman, A; Ogunc, S; Shen, ST; Wong, PY	1
Lerner, R; Lindström, P; Palmblad, J; Patarroyo, M	1
Crea, AE; Grandordy, BM; Krilis, S; Lacroix, H; Lee, TH; Mavoungou, E; Spur, BW	1
Brezinski, M; Crea, AE; Gant, V; Lee, TH; Marron, BE; Nicolaou, KC; Reardon, E; Serhan, CN; Spur, BW	1
Ballermann, BJ; Brady, HR; Brenner, BM; Persson, U; Serhan, CN	1
Serhan, CN	1
Crea, AE; Haskard, D; Horton, CE; Kyan-Aung, U; Lee, TH; Spur, BW	1
Dahlén, SE; Haeggström, J; Hedqvist, P; Nicolaou, KC; Palmertz, U; Raud, J	1
Dahlén, SE; Lindgren, JA; Rouzer, CA; Samuelsson, B; Serhan, CN	1
Goto, F	1
Borgeat, P; Picard, S	1
Gyllenhammar, H; Palmblad, J; Ringertz, B	1
Crea, AE; Jacques, CA; Lee, TH; Spur, BW	1
Hamberg, M; Hammarström, S; Samuelsson, B; Serhan, CN	1
Adams, J; Evans, JF; Fitzsimmons, BJ; Leblanc, Y; Rokach, J	1
Bratt, J; Lerner, R; Palmblad, J; Ringertz, B	1
Fiore, S; Reardon, EM; Romano, M; Serhan, CN	1
Heimburger, M; Lerner, R; Palmblad, J	1
Dudhane, A; Godfrey, HP; Lin, KT; Wong, PY	1
Chen, YQ; Honn, KV; Tang, DG	1
Brady, HR; Papayianni, A; Serhan, CN	1
Feng, Z; Godfrey, HP; Heilman, E; Lin, KT; Mandy, S; Strudwick, S; Wong, PY	1
Brady, HR; Hébert, MJ; Holthöfer, H; Takano, T	1
Chung-a-on, KO; Lee, TH; Soyombo, O; Spur, BW	1
Colgan, SP; Gronert, K; Serhan, CN	1
Arroyo, V; Clària, J; Ginès, P; Jiménez, W; Rivera, F; Rodés, J; Ros, J; Titos, E	1
Clark, JM; Fokin, VV; Levy, BD; Petasis, NA; Serhan, CN; Wakelam, MJ	1
Besse, A; Denizot, Y; Faucher, JL; Praloran, V; Trimoreau, F	1
Ito, M; Kikuta, Y; Kusunose, E; Kusunose, M	1
Denizot, Y; Desplat, V; Dulery, C; Praloran, V	1
Clish, CB; Petasis, NA; Pouliot, M; Serhan, CN; Van Dyke, TE	1
Denizot, Y; Godard, A; Praloran, V; Raher, S; Trimoreau, F	1
Denizot, Y; Desplat, V; Dupuis, F; Faucher, JL; Ivanovic, Z; Praloran, V	1
Kasyu, H; Kikuta, Y; Kusunose, E; Kusunose, M	1
Clish, CB; Gronert, K; Levy, BD; Schmidt, B; Serhan, CN	1
Devchand, PR; Qiu, FH; Serhan, CN; Wada, K	1
Coffman, TM; Flannery, P; Goulet, JL; Griffiths, RC; Koller, BH; Mannon, RB; Platt, JL; Ruiz, P	1
Arroyo, V; Clària, J; Gaya, J; López-Parra, M; Planagumà, A; Pueyo, G; Titos, E	1
Asadullah, K; Bauman, J; Colgan, SP; Fierro, IM; Giesen, C; Guilford, W; Parkinson, JF; Perez, HD; Schottelius, AJ	1
Kantarci, A; Oyaizu, K; Van Dyke, TE	1
Arita, M; Bannenberg, G; Devchand, PR; Gronert, K; Hong, S; Moussignac, RL; Serhan, CN	1
Barbanti, M; de Lima, OM; Distrutti, E; Fiorucci, S; Mencarelli, A; Morelli, A; Palazzini, E; Romano, M; Wallace, JL	1
Cirino, G; Distrutti, E; Fiorucci, S; Laufor, SA; Mencarelli, A; Morelli, A; Wallace, JL	1
Boutet, P; Bureau, F; Degand, G; Lekeux, P	1
Croxtall, JD; Gilroy, DW; Newson, J; Sawmynaden, P; Willoughby, DA	1
Andersson, P; Palmblad, J; Petasis, NA; Serhan, CN	1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Farce, M; Godard, P; Vachier, I	1
Bodzenta-Lukaszyk, A; Distler, O; Gay, RE; Gay, S; Kowal, K; Kowal-Bielecka, O; Michel, BA; Rojewska, J; Sierakowski, S	1
Arita, M; Kamisaki, Y; Katayama, K; Kudo, C; Nakajima, A; Serhan, CN; Wada, K	1
Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Jiang, X; Karlsson, L; Lundeen, KA; Rao, NL; Riley, JP; Williams, KN; Xue, X	1
Badovinac, RL; Hosokawa, I; Howell, TH; Karimbux, NY; Kawai, T; Kim, DM; Koszeghy, KL	1
Birnbaum, Y; Lin, Y; Perez-Polo, JR; Tieu, BC; Uretsky, BF; Ye, Y; Ye, Z	1
Dong, L; Liao, PY; Wu, SH; Yin, PL; Zhang, YM	2
Ballesteros, I; Caso, JR; Fernández-López, D; Hurtado, O; Lizasoain, I; Moro, MA; Nombela, F; Pereira, MP; Pradillo, JM; Serena, J; Sobrado, M; Vivancos, J	1
Bhavsar, PK; Chung, KF; Hew, MJ; Israel, E; Kazani, S; Levy, BD; Pfeffer, MA	1
Basselin, M; Chen, M; Ramadan, E; Rapoport, SI	1
Agerberth, B; Godson, C; Guiry, PJ; Haeggström, JZ; Wan, M	1
Altavilla, D; Bitto, A; David, A; Irrera, N; Minutoli, L; Rinaldi, M; Squadrito, F; Venuti, FS	1
Cai, L; Hao, H; Li, HH; Miao, S; Tang, K; Wu, L; Wu, P; Wu, Q; Xiong, J; Ye, DY; Zeng, P; Zou, LB	1
Balode, L; Beinare, M; Bukovskis, M; Gardjušina, V; Jurka, N; Kislina, A; Kopeika, U; Strazda, G; Taivāns, I	1
Britton, SL; Chawla, A; Feng, X; Koch, LG; Matthay, MA; Maze, M; Su, X; Terrando, N; Yan, Y	1
Bonini, M; Israel, E; Kazani, S; Levy, BD; Marigowda, G; Ono, E; Planaguma, A; Wechsler, ME; Zahid, M	1
Chen, H; Cheng, Q; Cheng, X; Huang, Y; Li, Y; Liu, H; Peng, H; Wu, P; Ye, D; Zeng, P; Zhang, D	1
Buchanan, PJ; Clarke, DT; Harvey, BJ; Linnane, B; McDermott, M; McNally, P; Millar, RG; Ringholz, FC; Urbach, V	1
Buret, AG; Duquette, SC; Feener, TD; Fischer, CD; Hollenberg, MD; Lucas, MJ; Morck, DW; Renaux, BS	1
Caliari, MV; Carvalho, NB; Corsetti, PP; de Almeida, LA; de Souza, MB; Fahel, JS; Gomes, MT; Machado, FS; Marinho, FA; Oliveira, SC	1
Kakutani, S; Kaneda, Y; Kawashima, H; Morita, I; Shibata, H; Tateishi, N	1
Das, UN; Ni, X; Shen, S; Yu, H; Zhang, C	1
Barreda, DR; Havixbeck, JJ; Hodgkinson, JW; Rieger, AM; Wong, ME	1
Chatterjee, S; Das, PN; Pedruzzi, G; Rao, KV	1
de Bruin, N; Ferreirós, N; Geisslinger, G; Homann, J; Schmidt, M; Scholich, K; Suo, J	1
Albano, GD; Anzalone, G; Bonanno, A; Chanez, P; Di Sano, C; Gagliardo, R; Gjomarkaj, M; Gras, D; La Grutta, S; Montalbano, AM; Profita, M; Riccobono, L; Vachier, I	1
Agudo, J; Bosch, F; Casellas, A; Elias, I; Ferré, T; Franckhauser, S; Garcia, M; Molas, M; Muñoz, S; Roca, C; Ruberte, J; Vilà, L	1
Arabshahi, A; Barnes, S; Bartiss, R; Musteata, FM; Prasain, J; Rahman, T; Sellati, TJ; Singh, A	1
Chen, LC; Chiu, CY; Hua, MC; Huang, JL; Huang, SK; Kuo, ML; Lai, SH; Liao, SL; Su, KW; Tsai, MH; Tseng, HM; Wu, AH; Yao, TC; Yeh, KW	1
Laskay, T; Plagge, M	1
Aronica, E; Colas, RA; Craparotta, I; Dalli, J; Foerch, P; Frigerio, F; Hansen, TV; Kaminski, RM; Leclercq, K; Marchini, S; Pasqualini, G; Perretti, M; Pistorius, K; Porcu, L; van Vliet, EA; Vandenplas, C; Vezzani, A	1
Amar, Y; Archambault, AS; Boilard, É; Cheikh, A; Côté, A; Doré, É; Dubuc, I; El Hassani, A; Fares, H; Flamand, L; Flamand, N; Flamand, O; Laviolette, M; Martin, C; Rakotoarivelo, V; Tijani, Y; Turcotte, C; Zaid, Y	1
Alpoim, PN; Barbosa, AS; da Silva, SPG; de Castro Pinto, KM; de Sousa, LP; Dusse, LMS; Lage, EM; Perucci, LO; Talvani, A; Teixeira, PG	1
Das, UN	1
AlaEddine, M; Authier, H; Bernad, J; Bouschbacher, M; Coste, A; Dardenne, C; Lefèvre, L; Meunier, E; Pipy, B; Salon, M	1

Reviews

5 review(s) available for lipoxin a4 and leukotriene b4

Article	Year
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science (New York, N.Y.), 1987, Sep-04, Volume: 237, Issue:4819 Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Central Nervous System; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Leukotriene B4; Lipoxins; SRS-A	1987
[Prostaglandins and related compounds]. Masui. The Japanese journal of anesthesiology, 1988, Volume: 37, Issue:1 Topics: Animals; Arachidonic Acids; Exotoxins; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Platelet Activating Factor; Prostaglandins; Thromboxanes	1988
Structural determination of leukotrienes and lipoxins. Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 14 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Neutrophils; Spectrum Analysis; SRS-A	1985
Neutrophil-mediated tissue injury in periodontal disease pathogenesis: findings from localized aggressive periodontitis. Journal of periodontology, 2003, Volume: 74, Issue:1 Topics: Adjuvants, Immunologic; Biomarkers; Calcium; Chemotaxis, Leukocyte; Cyclooxygenase 2; Diacylglycerol Kinase; Diglycerides; Dinoprostone; Gingival Crevicular Fluid; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Membrane Proteins; Neutrophil Activation; Neutrophils; Periodontitis; Peroxidases; Prostaglandin-Endoperoxide Synthases; Protein Kinases; Signal Transduction; Stereoisomerism	2003
Essential Fatty Acids and Their Metabolites in the Pathobiology of Inflammation and Its Resolution. Biomolecules, 2021, 12-14, Volume: 11, Issue:12 Topics: Animals; COVID-19; Dinoprostone; Fatty Acids, Essential; Humans; Inflammation; Leukotriene B4; Lipoxins; SARS-CoV-2	2021

Trials

3 trial(s) available for lipoxin a4 and leukotriene b4

Article	Year
The effect of aspirin on gingival crevicular fluid levels of inflammatory and anti-inflammatory mediators in patients with gingivitis. Journal of periodontology, 2007, Volume: 78, Issue:8 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dental Plaque Index; Dinoprostone; Female; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingivitis; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Leukotriene B4; Lipoxins; Male; Periodontal Pocket; Placebos	2007
High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:6 Topics: Adult; COVID-19; Female; Humans; Leukotriene B4; Leukotriene E4; Lipoxins; Lung; Male; Middle Aged; SARS-CoV-2	2021
Longitudinal assessment of leukotriene B4, lipoxin A4, and resolvin D1 plasma levels in pregnant women with risk factors for preeclampsia. Clinical biochemistry, 2021, Volume: 98 Topics: Adolescent; Adult; Docosahexaenoic Acids; Female; Humans; Leukotriene B4; Lipoxins; Longitudinal Studies; Pre-Eclampsia; Pregnancy; Risk Factors	2021

Other Studies

82 other study(ies) available for lipoxin a4 and leukotriene b4

Article	Year
Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. The Journal of biological chemistry, 1992, Aug-15, Volume: 267, Issue:23 Topics: Binding Sites; Binding, Competitive; GTP-Binding Proteins; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxins; Neutrophils; Subcellular Fractions; Tritium	1992
Lipoxin-induced migration of fish leukocytes. Journal of leukocyte biology, 1992, Volume: 51, Issue:2 Topics: Animals; Chemotaxis, Leukocyte; Hydroxyeicosatetraenoic Acids; Kidney; Leukotriene B4; Lipoxins; Macrophages; Neutrophils; Salmon	1992
Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells. Eicosanoids, 1992, Volume: 5, Issue:3-4 Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lung; Macrophage Activation; Macrophages, Alveolar; Middle Aged	1992
Inhibition of leukotriene B4 in neutrophils by lipoxins A4 and B4. Agents and actions, 1991, Volume: 32, Issue:1-2 Topics: Calcimycin; Cells, Cultured; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Neutrophils	1991
Inhibition of leukotriene B4-induced neutrophil migration by lipoxin A4: structure-function relationships. Biochemical and biophysical research communications, 1991, Nov-14, Volume: 180, Issue:3 Topics: Chemotaxis, Leukocyte; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotriene B4; Lipoxins; Molecular Structure; Neutrophils; Structure-Activity Relationship	1991
Lipoxins inhibit microvascular inflammatory actions of leukotriene B4. Advances in experimental medicine and biology, 1991, Volume: 314 Topics: Animals; Cheek; Chemotaxis, Leukocyte; Cricetinae; Hydroxyeicosatetraenoic Acids; Inflammation; Leukocytes; Leukotriene B4; Lipoxins; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Muscle, Smooth, Vascular	1991
Enzymatic formation and regulatory function of lipoxins and leukotriene B4 in rat kidney mesangial cells. Advances in experimental medicine and biology, 1991, Volume: 314 Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glomerular Mesangium; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene A4; Leukotriene B4; Leukotrienes; Lipoxins; Male; Rats; Rats, Inbred Strains	1991
Regulation of lipoxins (LX) and leukotriene B4 (LTB4) production in rat mesangial cells (MC). Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21B Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Epoxide Hydrolases; Glomerular Mesangium; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Leukotriene B4; Leukotrienes; Lipoxins; Lipoxygenase; Male; Rats; Rats, Inbred Strains	1991
Rapid adhesive responses of endothelial cells and of neutrophils induced by leukotriene B4 are mediated by leucocytic adhesion protein CD18. Scandinavian journal of immunology, 1990, Volume: 31, Issue:6 Topics: Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plastics; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Thrombin	1990
Lipoxin A4 inhibits phosphoinositide hydrolysis in human neutrophils. Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3 Topics: Dose-Response Relationship, Drug; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols	1990
Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases. The American review of respiratory disease, 1990, Volume: 141, Issue:6 Topics: Adult; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotriene E4; Lipoxins; Lung Diseases; Male; Middle Aged; Radioimmunoassay; Sarcoidosis; SRS-A	1990
Lipoxins A4 and B4 inhibit leukotriene B4 generation from human neutrophil leukocyte suspensions. Immunology letters, 1990, Volume: 24, Issue:4 Topics: Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Lipoxins; Masoprocol; Neutrophils; Radioimmunoassay	1990
Leukotrienes stimulate neutrophil adhesion to mesangial cells: modulation with lipoxins. The American journal of physiology, 1990, Volume: 259, Issue:5 Pt 2 Topics: Cell Adhesion; Cycloheximide; Dactinomycin; Glomerular Mesangium; Humans; Hydrogen Peroxide; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Neutrophils; SRS-A	1990
On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE. Biochimica et biophysica acta, 1989, Aug-08, Volume: 1004, Issue:2 Topics: Calcimycin; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Leukotrienes; Lipoxins; Neutrophils; Spectrophotometry, Ultraviolet	1989
Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. Clinical science (London, England : 1979), 1989, Volume: 77, Issue:2 Topics: Calcium; Cell Adhesion; Chemotaxis, Leukocyte; Humans; Hydroxyeicosatetraenoic Acids; Isomerism; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils	1989
Lipoxin A4 inhibits leukotriene B4-induced inflammation in the hamster cheek pouch. Acta physiologica Scandinavica, 1989, Volume: 137, Issue:4 Topics: Animals; Capillary Permeability; Cheek; Cricetinae; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene B4; Lipoxins; Male; Mesocricetus; Microcirculation	1989
19-Hydroxyprostaglandin B2 as an internal standard for on-line extraction-high-performance liquid chromatography analysis of lipoxygenase products. Analytical biochemistry, 1988, Volume: 171, Issue:2 Topics: Calcimycin; Chromatography, High Pressure Liquid; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Lipoxins; Lipoxygenase; Prostaglandins; Prostaglandins B	1988
Effects of lipoxins A and B on functional responses of human granulocytes. Advances in experimental medicine and biology, 1988, Volume: 229 Topics: Calcium; Cell Aggregation; Chemotaxis, Leukocyte; Granulocytes; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Lipoxins; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Pancreatic Elastase; Stereoisomerism	1988
The contractile activities of lipoxin A4 and lipoxin B4 for guinea-pig airway tissues. British journal of pharmacology, 1988, Volume: 95, Issue:2 Topics: Animals; Chromones; Guinea Pigs; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; SRS-A; Stereoisomerism; Trachea	1988
The lipoxins. Stereochemical identification and determination of their biosynthesis. The Journal of biological chemistry, 1985, Oct-25, Volume: 260, Issue:24 Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Isomerism; Leukocytes; Leukotriene A4; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lipoxins; Lipoxygenase; Magnetic Resonance Spectroscopy	1985
Mechanisms for lipoxin A4 induced neutrophil dependent cytotoxicity for human endothelial cells. Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23 Topics: Azepines; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Triazoles; Umbilical Veins; Virulence Factors, Bordetella	1995
Induction of functional lipoxin A4 receptors in HL-60 cells. Blood, 1993, Jun-15, Volume: 81, Issue:12 Topics: Binding, Competitive; Dactinomycin; Dimethyl Sulfoxide; Enzyme Activation; Humans; Hydroxyeicosatetraenoic Acids; Leukemia, Promyelocytic, Acute; Leukotriene B4; Lipoxins; Neutrophils; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Type C Phospholipases	1993
Lipoxin A4 induces hyperadhesiveness in human endothelial cells for neutrophils. Blood, 1993, Aug-01, Volume: 82, Issue:3 Topics: Calcium; Cell Adhesion; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Interleukin-1; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin	1993
Identification and characterization of a high-affinity leukotriene B4 receptor on guinea pig T lymphocytes and its regulation by lipoxin A4. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2 Topics: Animals; Carbazoles; Female; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Indole Alkaloids; Inflammation; Leukotriene B4; Lipoxins; Protein Kinase C; Receptors, Leukotriene B4; T-Lymphocytes; Tetradecanoylphorbol Acetate	1996
Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Apoptosis; Arachidonate 12-Lipoxygenase; Base Sequence; Cell Division; Cell Line; Cell Survival; Female; Homeostasis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotriene C4; Leukotrienes; Lipid Peroxides; Lipoxins; Masoprocol; Molecular Sequence Data; Oligonucleotides, Antisense; Plasmids; Rats; Transfection	1996
Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. Journal of immunology (Baltimore, Md. : 1950), 1996, Mar-15, Volume: 156, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; CD18 Antigens; Cell Adhesion; Cell Communication; Cell Movement; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxins; Neutrophils; P-Selectin	1996
Leukotriene B4 modulates in vivo expression of delayed-type hypersensitivity by a receptor-mediated mechanism: regulation by lipoxin A4. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Gene Expression; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Male; Skin	1996
Sequential morphologic events during apoptosis of human neutrophils. Modulation by lipoxygenase-derived eicosanoids. Journal of immunology (Baltimore, Md. : 1950), 1996, Oct-01, Volume: 157, Issue:7 Topics: Animals; Apoptosis; Cells, Cultured; Chromatin; DNA; Endothelium, Vascular; Flow Cytometry; Fluorescent Dyes; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lipoxygenase; Neutrophils; Rats; Receptors, Leukotriene B4; Signal Transduction	1996
Stimulation of protein kinase C redistribution and inhibition of leukotriene B4-induced inositol 1,4,5-trisphosphate generation in human neutrophils by lipoxin A4. British journal of pharmacology, 1996, Volume: 117, Issue:6 Topics: Blotting, Western; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Inositol 1,4,5-Trisphosphate; Leukotriene B4; Lipoxins; Neutrophils; Protein Kinase C; Receptors, Leukotriene B4	1996
Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Hypoxia; Dinoprostone; Eicosanoids; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Leukotriene B4; Ligands; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Sodium-Hydrogen Exchangers; Virulence Factors, Bordetella	1998
Altered biosynthesis of leukotrienes and lipoxins and host defense disorders in patients with cirrhosis and ascites. Gastroenterology, 1998, Volume: 115, Issue:1 Topics: Angiotensin II; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Ascites; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Liver Cirrhosis; Neutrophils; RNA, Messenger	1998
Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:8 Topics: Aspirin; Brassica; Enzyme Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotriene B4; Lipoxins; Neutrophils; Phospholipase D; Polyisoprenyl Phosphates; Recombinant Proteins; Signal Transduction; Stereoisomerism; Superoxides	1999
Prostaglandin E2 regulates macrophage colony stimulating factor secretion by human bone marrow stromal cells. Biochimica et biophysica acta, 1999, Jul-08, Volume: 1450, Issue:3 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Apoptosis; Bone Marrow Cells; Cell Division; Cyclic AMP; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Macrophage Colony-Stimulating Factor; Prostaglandins E; Tumor Necrosis Factor-alpha	1999
Purification and characterization of recombinant rat hepatic CYP4F1. Archives of biochemistry and biophysics, 1999, Sep-15, Volume: 369, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Hydroxylation; Leukotriene B4; Lipoxins; Liver; Liver Neoplasms; Mixed Function Oxygenases; Neoplasm Proteins; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity	1999
Incorporation and effect of arachidonic acid on the growth of human myeloma cell lines. Mediators of inflammation, 1999, Volume: 8, Issue:2 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acylation; Arachidonic Acid; Cell Division; Cell Membrane; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxins; Lipoxygenase; Membrane Lipids; Multiple Myeloma; Phospholipids; Triglycerides; Tumor Cells, Cultured	1999
Lipoxin A(4) analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease. Biochemistry, 2000, Apr-25, Volume: 39, Issue:16 Topics: Aggressive Periodontitis; Animals; Aspirin; Bacteroidaceae Infections; Bronchoalveolar Lavage Fluid; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Gingival Crevicular Fluid; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Lung; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Myocardium; Neutrophil Infiltration; Neutrophils; Porphyromonas gingivalis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger	2000
Effect of cytokines and lipid mediators on the synthesis of interleukin 1 beta by human bone marrow stromal cells. Cytokine, 2000, Volume: 12, Issue:5 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Bone Marrow Cells; Cells, Cultured; Cytokines; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Leukotriene B4; Lipid Metabolism; Lipoxins; Platelet Activating Factor; Stromal Cells	2000
Effects of lipoxygenase metabolites of arachidonic acid on the growth of human blood CD34(+) progenitors. Blood cells, molecules & diseases, 2000, Volume: 26, Issue:5 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Antigens, CD34; Antigens, Differentiation; Arachidonic Acids; Cell Count; Cell Division; Colony-Forming Units Assay; Culture Media; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Erythropoietin; Hematopoietic Stem Cells; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lipoxygenase; Methylcellulose; Solutions; Thymidine; Time Factors	2000
Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. Archives of biochemistry and biophysics, 2000, Nov-15, Volume: 383, Issue:2 Topics: 5' Untranslated Regions; Alternative Splicing; Amino Acid Sequence; Animals; Arachidonic Acid; Base Sequence; Blotting, Northern; Brain; Catalysis; Clofibrate; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; DNA, Complementary; Exons; Hydroxyeicosatetraenoic Acids; Introns; Laurates; Leukotriene B4; Lipoxins; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microsomes, Liver; Mixed Function Oxygenases; Models, Genetic; Molecular Sequence Data; Prostaglandins A; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Tissue Distribution; Transcription, Genetic; Transfection	2000
Lipid mediator class switching during acute inflammation: signals in resolution. Nature immunology, 2001, Volume: 2, Issue:7 Topics: Animals; Arachidonate 15-Lipoxygenase; Base Sequence; Dinoprostone; DNA, Complementary; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipid Metabolism; Lipids; Lipoxins; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Molecular Structure; Neutrophils; Pleural Effusion; RNA, Messenger; Signal Transduction	2001
Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:14 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; DNA, Complementary; Gene Expression Regulation; GTP-Binding Proteins; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Models, Biological; Neutrophils; Receptors, Cell Surface; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription, Genetic; Up-Regulation	2001
Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice. Journal of immunology (Baltimore, Md. : 1950), 2001, Dec-01, Volume: 167, Issue:11 Topics: Animals; Arachidonate 5-Lipoxygenase; Crosses, Genetic; Cytokines; Graft Rejection; Hydroxyeicosatetraenoic Acids; Kidney Function Tests; Kidney Transplantation; Leukotriene B4; Lipoxins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Knockout; RNA, Messenger; Thromboxane A2; Thromboxane B2	2001
Aspirin (ASA) regulates 5-lipoxygenase activity and peroxisome proliferator-activated receptor alpha-mediated CINC-1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA-triggered 15-epi-LXA4. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:14 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Aspirin; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotactic Factors; Dinoprostone; Hepatocytes; Hydroxyeicosatetraenoic Acids; Intercellular Signaling Peptides and Proteins; Kupffer Cells; Leukotriene B4; Lipoxins; Liver; Models, Biological; Rats; Receptors, Cytoplasmic and Nuclear; Transcription Factors	2002
An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile. Journal of immunology (Baltimore, Md. : 1950), 2002, Dec-15, Volume: 169, Issue:12 Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Cell Movement; Chemotaxis, Leukocyte; Croton Oil; Disease Models, Animal; Diterpenes; Female; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Hypersensitivity, Delayed; Iloprost; Inflammation; Leukotriene B4; Lipoxins; Mice; Phthalic Anhydrides; Skin; Terpenes	2002
Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:6 Topics: 3T3 Cells; Animals; Cell Line; Chromatography, Liquid; Dinoprostone; Female; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene B4; Lipoxins; Male; Mass Spectrometry; Mice; Mice, Transgenic; Neutrophil Infiltration; NF-kappa B; Peritoneum; Peritonitis; Plasmids; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Skin; Transfection; Tumor Necrosis Factor-alpha; Zymosan	2003
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:9 Topics: Acetates; Acetylation; Adaptation, Physiological; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastric Mucosa; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rats	2003
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin. British journal of pharmacology, 2003, Volume: 139, Issue:7 Topics: Acetates; Acetylation; Adhesiveness; Arachidonate 5-Lipoxygenase; Aspirin; CD11a Antigen; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; E-Selectin; Eicosanoids; Endothelial Cells; Endothelium, Vascular; Fatty Alcohols; Glycols; Humans; Isoenzymes; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxins; Lipoxygenase; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrans; Pyrroles; Quinolines; Quinolones; Umbilical Cord; Up-Regulation	2003
Imbalance between lipoxin A4 and leukotriene B4 in chronic mastitis-affected cows. Journal of dairy science, 2003, Volume: 86, Issue:11 Topics: Acute Disease; Animals; Case-Control Studies; Cattle; Cell Count; Chronic Disease; Female; Leukotriene B4; Lipoxins; Macrophages; Mammary Glands, Animal; Mastitis, Bovine; Milk; Neutrophils	2003
A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:3 Topics: Acute Disease; Animals; Arachidonic Acid; Carrageenan; Cells, Cultured; Convalescence; Corticosterone; Cyclooxygenase 2; Disease Progression; Enzyme Induction; Epithelial Cells; Fibroblasts; Group II Phospholipases A2; Group IV Phospholipases A2; Group V Phospholipases A2; Group VI Phospholipases A2; Interleukin-1; Isoenzymes; Leukotriene B4; Lipoxins; Macrophages; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar	2004
Interactions between lipoxin A4, the stable analogue 16-phenoxy-lipoxin A4 and leukotriene B4 in cytokine generation by human monocytes. Scandinavian journal of immunology, 2004, Volume: 60, Issue:3 Topics: Cytokines; Humans; Interleukin-1; Interleukin-6; Leukotriene B4; Lipoxins; Monocytes; Receptors, Interleukin-1	2004
Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound. The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:1 Topics: Adult; Asthma; Female; Humans; Interleukin-8; Leukotriene B4; Lipoxins; Male; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sputum	2005
Cyclooxygenase- and lipoxygenase-derived eicosanoids in bronchoalveolar lavage fluid from patients with scleroderma lung disease: an imbalance between proinflammatory and antiinflammatory lipid mediators. Arthritis and rheumatism, 2005, Volume: 52, Issue:12 Topics: Adult; Aged; Bronchoalveolar Lavage Fluid; Dinoprostone; Eicosanoids; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lipoxygenase; Lung Diseases; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Scleroderma, Systemic	2005
Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:11 Topics: Animals; Apoptosis; Brain; Cell Differentiation; Cell Division; Chromatin; Female; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Mice; Mice, Inbred BALB C; Neurons; Oligonucleotide Array Sequence Analysis; Phenylpropionates; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stem Cells	2006
Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Ascitic Fluid; Benzothiazoles; Dogs; Ear; Edema; Eicosanoids; Enzyme Inhibitors; Epoxide Hydrolases; Female; Humans; Hydroxyurea; Inflammation; Leukotriene B4; Leukotriene C4; Lipoxins; Lipoxygenase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neutrophil Infiltration; Peritonitis; Piperidines; Recombinant Proteins	2007
Phosphorylation of 5-lipoxygenase at ser523 by protein kinase A determines whether pioglitazone and atorvastatin induce proinflammatory leukotriene B4 or anti-inflammatory 15-epi-lipoxin a4 production. Journal of immunology (Baltimore, Md. : 1950), 2008, Sep-01, Volume: 181, Issue:5 Topics: Animals; Arachidonate 5-Lipoxygenase; Atorvastatin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Heptanoic Acids; Immunologic Factors; Isoquinolines; Leukotriene B4; Lipoxins; Male; Myocardium; Phosphorylation; Pioglitazone; Pyrroles; Rats; Rats, Sprague-Dawley; Serine; Sulfonamides; Thiazolidinediones	2008
Elevated expressions of 15-lipoxygenase and lipoxin A4 in children with acute poststreptococcal glomerulonephritis. The American journal of pathology, 2009, Volume: 174, Issue:1 Topics: Arachidonate 15-Lipoxygenase; Chemotaxis, Leukocyte; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Glomerulonephritis; Humans; Hydroxyeicosatetraenoic Acids; Immunohistochemistry; Leukocytes; Leukotriene B4; Lipoxins; Neutrophils; Streptococcal Infections	2009
Inverse temporal changes of lipoxin A4 and leukotrienes in children with Henoch-Schönlein purpura. Prostaglandins, leukotrienes, and essential fatty acids, 2009, Volume: 80, Issue:4 Topics: C-Reactive Protein; Chemotaxis; Child; Humans; IgA Vasculitis; Leukocytes; Leukotriene B4; Leukotriene E4; Lipoxins	2009
Synthesis of lipoxin A4 by 5-lipoxygenase mediates PPARgamma-dependent, neuroprotective effects of rosiglitazone in experimental stroke. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Mar-25, Volume: 29, Issue:12 Topics: Animals; Arachidonate 5-Lipoxygenase; Brain; Brain Infarction; Infarction, Middle Cerebral Artery; Leukotriene B4; Lipoxins; Mice; Neuroprotective Agents; PPAR gamma; Rats; Rosiglitazone; Stroke; Thiazolidinediones	2009
Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma. Respiratory research, 2010, Jun-07, Volume: 11 Topics: Adrenal Cortex Hormones; Adult; Asthma; Bronchoscopy; Case-Control Studies; Dexamethasone; Down-Regulation; Female; Forced Expiratory Volume; Humans; Immunoenzyme Techniques; Inflammation Mediators; Leukotriene B4; Lipopolysaccharides; Lipoxins; Macrophages, Alveolar; Male; Middle Aged; Severity of Illness Index; Young Adult	2010
Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites. Neurochemical research, 2011, Volume: 36, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Brain; Dinoprostone; Humans; Leukotriene B4; Lipopolysaccharides; Lipoxins; Male; Rats; Rats, Inbred F344; Thromboxane B2	2011
Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:5 Topics: Antimicrobial Cationic Peptides; Blotting, Western; Calcium; Cathelicidins; Cells, Cultured; Eicosapentaenoic Acid; Electrophoresis, Polyacrylamide Gel; Group IV Phospholipases A2; Humans; Immunoenzyme Techniques; Leukotriene B4; Lipoxins; Neutrophils; Receptors, Formyl Peptide; Receptors, Leukotriene B4; Receptors, Lipoxin	2011
Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis. Critical care (London, England), 2012, Feb-22, Volume: 16, Issue:1 Topics: Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Catechin; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Disease Models, Animal; Drug Combinations; Extracellular Signal-Regulated MAP Kinases; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Liver; Lung; Mice, Inbred C57BL; NF-kappa B; Peroxidase; Sepsis	2012
Lipoxin A4 inhibits 5-lipoxygenase translocation and leukotrienes biosynthesis to exert a neuroprotective effect in cerebral ischemia/reperfusion injury. Journal of molecular neuroscience : MN, 2012, Volume: 48, Issue:1 Topics: Animals; Animals, Newborn; Arachidonate 5-Lipoxygenase; Astrocytes; Brain Edema; Brain Ischemia; Disease Models, Animal; Enzyme Inhibitors; Flavonoids; Glucose; Leukotriene B4; Leukotriene C4; Leukotrienes; Lipoxins; Male; MAP Kinase Signaling System; Neuroprotective Agents; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger	2012
Lipoxygenase-derived arachidonic acid metabolites in chronic obstructive pulmonary disease. Medicina (Kaunas, Lithuania), 2012, Volume: 48, Issue:6 Topics: Female; Humans; Leukotriene B4; Lipoxins; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Sputum	2012
Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. Molecular medicine (Cambridge, Mass.), 2013, Feb-08, Volume: 18 Topics: Animals; Anti-Inflammatory Agents; CD3 Complex; Cell Polarity; Choline; Cognition Disorders; Disease Models, Animal; Hippocampus; Inflammation; Leukotriene B4; Lipoxins; Lymphocyte Count; Macrophages; Male; Metabolic Syndrome; Physical Conditioning, Animal; Postoperative Period; Rats; Receptors, Adrenergic, beta-2; Signal Transduction; Spleen; T-Lymphocytes, Regulatory	2013
Exhaled breath condensate eicosanoid levels associate with asthma and its severity. The Journal of allergy and clinical immunology, 2013, Volume: 132, Issue:3 Topics: Adolescent; Adult; Asthma; Breath Tests; Exhalation; Female; Humans; Leukotriene B4; Lipoxins; Male; Middle Aged; Severity of Illness Index; Young Adult	2013
Glucocorticoids sensitize rat placental inflammatory responses via inhibiting lipoxin A4 biosynthesis. Biology of reproduction, 2014, Volume: 90, Issue:4 Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line; Dexamethasone; Dinoprostone; Female; Glucocorticoids; Humans; Inflammation; Leukotriene B4; Lipopolysaccharides; Lipoxins; MAP Kinase Signaling System; NF-kappa B; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley	2014
Reduced 15-lipoxygenase 2 and lipoxin A4/leukotriene B4 ratio in children with cystic fibrosis. The European respiratory journal, 2014, Volume: 44, Issue:2 Topics: Anti-Bacterial Agents; Arachidonate 15-Lipoxygenase; Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Inflammation; Leukotriene A4; Leukotriene B4; Lipoxins; Longitudinal Studies; Lung; Lung Diseases; Macrophages, Alveolar; Male; Neutrophils	2014
Tulathromycin exerts proresolving effects in bovine neutrophils by inhibiting phospholipases and altering leukotriene B4, prostaglandin E2, and lipoxin A4 production. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Calcimycin; Cattle; Dinoprostone; Disaccharides; Heterocyclic Compounds; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Lung; Male; Neutrophils; Particulate Matter; Phospholipases A2; Pneumonia; Primary Cell Culture; Zymosan	2014
5-Lipoxygenase negatively regulates Th1 response during Brucella abortus infection in mice. Infection and immunity, 2015, Volume: 83, Issue:3 Topics: Animals; Arachidonate 5-Lipoxygenase; Bacterial Load; Brucella abortus; Brucellosis; Disease Progression; Gene Expression Regulation; Host-Pathogen Interactions; Immunity, Innate; Injections, Intraperitoneal; Interferon-gamma; Interleukin-12; Leukotriene B4; Lipoxins; Liver; Macrophages; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Spleen; Th1 Cells	2015
Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. Lipids in health and disease, 2015, Jan-16, Volume: 14 Topics: Animals; Arachidonic Acid; Arthritis, Experimental; Bone and Bones; Dietary Supplements; Dinoprostone; Disease Models, Animal; Gene Expression Regulation; Leukotriene B4; Lipoxins; Male; Rats, Inbred Lew; Time Factors	2015
Growth inhibitory effect of polyunsaturated fatty acids (PUFAs) on colon cancer cells via their growth inhibitory metabolites and fatty acid composition changes. PloS one, 2015, Volume: 10, Issue:4 Topics: Antimetabolites, Antineoplastic; Arachidonate 5-Lipoxygenase; Cell Line, Tumor; Colorectal Neoplasms; Cyclooxygenase 2; Dinoprostone; Fatty Acids; Fatty Acids, Unsaturated; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Intramolecular Oxidoreductases; Leukotriene B4; Lipocalins; Lipoxins; Prostaglandin-E Synthases	2015
Neutrophil contributions to the induction and regulation of the acute inflammatory response in teleost fish. Journal of leukocyte biology, 2016, Volume: 99, Issue:2 Topics: Acute Disease; Animals; Apoptosis; Goldfish; Immunity, Innate; Kidney; Leukotriene B4; Lipoxins; Macrophage Activation; Macrophages, Peritoneal; Neutrophils; Peritonitis; Phagocytosis; Reactive Oxygen Species; Respiratory Burst; Time Factors; Zymosan	2016
Understanding PGE2, LXA4 and LTB4 balance during Mycobacterium tuberculosis infection through mathematical model. Journal of theoretical biology, 2016, Jan-21, Volume: 389 Topics: Apoptosis; Computer Simulation; Dinoprostone; Humans; Inflammation; Leukotriene B4; Lipoxins; Macrophages; Models, Theoretical; Mycobacterium Infections; Mycobacterium tuberculosis; Necrosis; Phenotype; Treatment Outcome; Virulence	2016
In Vivo Availability of Pro-Resolving Lipid Mediators in Oxazolone Induced Dermal Inflammation in the Mouse. PloS one, 2015, Volume: 10, Issue:11 Topics: Animals; Calibration; Chromatography, Liquid; Cyclooxygenase 2; Dermis; Hydroxyeicosatetraenoic Acids; Inflammation; Inflammation Mediators; Injections, Subcutaneous; Leukotriene B4; Lipids; Lipoxins; Luminescent Measurements; Mass Spectrometry; Mice, Inbred C57BL; Oxazolone; Peptidylprolyl Isomerase; Reproducibility of Results; Ribosomal Proteins	2015
Airway lipoxin A4/formyl peptide receptor 2-lipoxin receptor levels in pediatric patients with severe asthma. The Journal of allergy and clinical immunology, 2016, Volume: 137, Issue:6 Topics: Adrenal Cortex Hormones; Asthma; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Humans; Immunoglobulin E; Leukocytes; Leukotriene B4; Lipoxins; Male; Phosphorylation; Receptors, Formyl Peptide; Receptors, Glucocorticoid; Receptors, Lipoxin; Respiratory Function Tests; Severity of Illness Index; Signal Transduction; Skin Tests; Sputum	2016
ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. Diabetes, 2016, Volume: 65, Issue:8 Topics: 5-Lipoxygenase-Activating Proteins; Adipose Tissue; Adipose Tissue, White; Animals; Diet, High-Fat; Gene Expression; Hep G2 Cells; Humans; Insulin Resistance; Leukotriene B4; Lipoxins; Mice; Mice, Transgenic; Obesity; Thermogenesis	2016
Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia. Journal of leukocyte biology, 2017, Volume: 101, Issue:2 Topics: Acute Disease; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Bone Marrow Cells; Cell Death; Chemokines; Chronic Disease; Dinoprostone; Disease Susceptibility; Down-Regulation; Francisella tularensis; Immunity; Indoles; Inflammation Mediators; Leukotriene B4; Lipoxins; Macrophages; Metabolome; Mice, Inbred C57BL; Organ Specificity; Respiratory Tract Infections; Tularemia	2017
A composite of exhaled LTB Allergy, 2018, Volume: 73, Issue:3 Topics: Algorithms; Area Under Curve; Asthma; Biomarkers; Breath Tests; Child; Child, Preschool; Dinoprostone; Eicosanoids; Female; Forced Expiratory Volume; Humans; Leukotriene B4; Leukotriene E4; Lipoxins; Male; Nitric Oxide; ROC Curve; Sensitivity and Specificity	2018
Early Production of the Neutrophil-Derived Lipid Mediators LTB BioMed research international, 2017, Volume: 2017 Topics: Humans; Leishmania major; Leishmaniasis, Cutaneous; Leukotriene B4; Lipoxins; Neutrophils	2017
n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis. Brain : a journal of neurology, 2018, 11-01, Volume: 141, Issue:11 Topics: Animals; Anticonvulsants; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; CD11b Antigen; Cytokines; Dinoprostone; Disease Models, Animal; Docosahexaenoic Acids; Encephalitis; Epilepsy; Gene Expression Regulation; Hippocampus; Kainic Acid; Leukotriene B4; Lipid Metabolism; Lipoxins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic	2018
Topical Aspirin Administration Improves Cutaneous Wound Healing in Diabetic Mice Through a Phenotypic Switch of Wound Macrophages Toward an Anti-inflammatory and Proresolutive Profile Characterized by LXA4 Release. Diabetes, 2022, 10-01, Volume: 71, Issue:10 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Diabetes Mellitus, Experimental; Inflammation; Leukotriene A4; Leukotriene B4; Lipoxins; Macrophages; Mice; Phenotype; Skin; Wound Healing	2022