Compounds > lipoxin a4

lipoxin a4 and interleukin-8

lipoxin a4 has been researched along with interleukin-8 in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's9 (47.37)29.6817
2010's8 (42.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gewirtz, A; Gronert, K; Madara, JL; Serhan, CN1
Gewirtz, AT; Gronert, K; Madara, JL; McCormick, B; Neish, AS; Petasis, NA; Serhan, CN1
Fiore, S; Sodin-Semrl, S; Taddeo, B; Tseng, D; Varga, J1
Baird, AW; Bernasconi, G; Brady, HR; Cottell, D; Godson, C; Goh, J; MacMathuna, P; O'Keane, C; Petasis, NA; Watson, RW1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Godard, P; Vachier, I1
Filep, JG; József, L; Petasis, NA; Serhan, CN; Zouki, C1
Gewirtz, AT; Kucharzik, T; Madara, JL; Merlin, D; Williams, IR1
Bonnans, C; Bousquet, J; Chanez, P; Chavis, C; Farce, M; Godard, P; Vachier, I1
Bonnans, C; Chanez, P; Chavis, C; Godard, P; Gras, D; Mainprice, B; Vachier, I1
Chiron, R; Grumbach, YY; Quynh, NV; Urbach, V; Verriere, V1
Decker, Y; Godson, C; McBean, G1
Tao, HX; Wu, SH; Yin, PL; Zhang, YM1
Chen, H; Furue, M; Moroi, Y; Nakahara, T; Takahara, M; Takeuchi, S; Tu, Y; Uchi, H; Xie, L1
Anderson, GP; Bozinovski, S; Hutchinson, A; Irving, LB; Levy, BD; McQualter, JL; Merritt, AS; Thompson, M; Uddin, M; Vlahos, R; Wark, PA1
Bonnans, C; Bourdin, A; Chanez, P; de Senneville, L; Gras, D; Vachier, I1
Domenech, T; Jover, I; Malhotra, R; Miralpeix, M; Planagumà, A; Ramos, I; Sentellas, S1
Allen, MJ; Beckham, Y; Birukov, KG; Birukova, AA; Gardel, ML; Leff, A; Mambetsariev, I; Meliton, A; Meng, F; Tian, Y1
Chen, XQ; Kong, X; Wu, SH; Zhang, L1
Alaçam, H; Aydoğdu, A; Lütfioğlu, M; Pamuk, F; Sakallioğlu, EE1

Trials

1 trial(s) available for lipoxin a4 and interleukin-8

ArticleYear
Lipoxin A(4) and interleukin-8 levels in cystic fibrosis sputum after antibiotherapy.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2008, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Infusions, Intravenous; Interleukin-8; Lipoxins; Male; Middle Aged; Prospective Studies; Sputum; Treatment Outcome; Vital Capacity; Young Adult

2008

Other Studies

18 other study(ies) available for lipoxin a4 and interleukin-8

ArticleYear
Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release.
    The Journal of experimental medicine, 1998, Apr-20, Volume: 187, Issue:8

    Topics: Aspirin; Caco-2 Cells; Cloning, Molecular; Cyclooxygenase 2; Epithelial Cells; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Interferon-gamma; Interleukin-13; Interleukin-8; Intestinal Mucosa; Isoenzymes; Lipoxins; Membrane Proteins; Models, Immunological; Molecular Sequence Data; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs.
    The Journal of clinical investigation, 1998, May-01, Volume: 101, Issue:9

    Topics: Cells, Cultured; Chemokines; Chemotactic Factors; Chemotaxis, Leukocyte; Drug Stability; Hydroxyeicosatetraenoic Acids; Interleukin-8; Intestinal Mucosa; Lipoxins; Neutrophils; Salmonella typhimurium; Stereoisomerism; Structure-Activity Relationship

1998
Lipoxin A4 inhibits IL-1 beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Mar-01, Volume: 164, Issue:5

    Topics: Cells, Cultured; Fibroblasts; Humans; Hydroxyeicosatetraenoic Acids; Immunosuppressive Agents; Interleukin-1; Interleukin-6; Interleukin-8; Lipoxins; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; RNA, Messenger; Synovial Membrane; Tissue Inhibitor of Metalloproteinases; Up-Regulation

2000
Lipoxin A(4) and aspirin-triggered 15-epi-lipoxin A(4) antagonize TNF-alpha-stimulated neutrophil-enterocyte interactions in vitro and attenuate TNF-alpha-induced chemokine release and colonocyte apoptosis in human intestinal mucosa ex vivo.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Sep-01, Volume: 167, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Line; Chemokine CCL2; Chemokine CCL5; Chemokines; Enterocytes; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Interleukin-8; Intestinal Mucosa; Lipoxins; Microscopy, Electron; Neutrophils; Tumor Necrosis Factor-alpha

2001
Lipoxins are potential endogenous antiinflammatory mediators in asthma.
    American journal of respiratory and critical care medicine, 2002, Jun-01, Volume: 165, Issue:11

    Topics: Asthma; Base Sequence; Biomarkers; Bronchial Provocation Tests; Female; Humans; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Interleukin-8; Lipoxins; Male; Molecular Sequence Data; Probability; Prospective Studies; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sampling Studies; Sensitivity and Specificity; Severity of Illness Index; Sputum; Statistics, Nonparametric

2002
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Oct-01, Volume: 99, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-8; Leukocytes; Lipoxins; Lymphocytes; Neutrophils; NF-kappa B; Peroxynitrous Acid; Ribonucleases; Superoxides; Transcription Factor AP-1

2002
Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium.
    American journal of physiology. Cell physiology, 2003, Volume: 284, Issue:4

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Cyclopropanes; Genetic Vectors; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-8; Intestinal Mucosa; Leukotriene Antagonists; Lipoxins; Membrane Proteins; Quinolines; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Leukotriene; Receptors, Lipoxin; Retroviridae; Sulfides; Tissue Distribution; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2003
Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound.
    The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:1

    Topics: Adult; Asthma; Female; Humans; Interleukin-8; Leukotriene B4; Lipoxins; Male; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sputum

2005
Synthesis and anti-inflammatory effect of lipoxins in human airway epithelial cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2007, Volume: 61, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Bronchi; Cells, Cultured; Chromatography, High Pressure Liquid; Epithelial Cells; Humans; Hydroxyeicosatetraenoic Acids; Immunochemistry; Interleukin-8; Lipoxins; Receptors, Formyl Peptide; Receptors, Lipoxin; Respiratory Mucosa; Tumor Necrosis Factor-alpha

2007
Lipoxin A4 inhibits IL-1beta-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells.
    American journal of physiology. Cell physiology, 2009, Volume: 296, Issue:6

    Topics: Apolipoproteins; Astrocytoma; Brain Neoplasms; Calcium; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-8; Lipoxins; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Receptors, Formyl Peptide; Receptors, Lipoxin; RNA, Messenger; Transcriptional Activation; Up-Regulation

2009
Reversed changes of lipoxin A4 and leukotrienes in children with asthma in different severity degree.
    Pediatric pulmonology, 2010, Volume: 45, Issue:4

    Topics: Asthma; C-Reactive Protein; Child; Child, Preschool; Female; Humans; Immunoglobulin E; Interleukin-13; Interleukin-5; Interleukin-8; Leukotrienes; Lipoxins; Male; Respiratory Function Tests

2010
Lipoxin A(4), a potential anti-inflammatory drug targeting the skin.
    Journal of dermatological science, 2011, Volume: 62, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cytokines; Epidermis; Fibroblasts; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Interleukin-8; Keratinocytes; Lipoxins; Models, Biological; Psoriasis; Skin

2011
Serum amyloid A opposes lipoxin A₄ to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Jan-17, Volume: 109, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Epithelial Cells; Epithelium; Glucocorticoids; Humans; Interleukin-8; Lipoxins; Lung; Macrophages; Mice; Mucous Membrane; Neutrophil Activation; Neutrophils; Pneumonia; Pulmonary Disease, Chronic Obstructive; Receptors, Formyl Peptide; Receptors, Lipoxin; Serum Amyloid A Protein

2012
An ex vivo model of severe asthma using reconstituted human bronchial epithelium.
    The Journal of allergy and clinical immunology, 2012, Volume: 129, Issue:5

    Topics: Adult; Aged; Airway Remodeling; Asthma; Bronchi; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Disease Progression; Feasibility Studies; Female; Humans; Interleukin-8; Lipoxins; Lipoxygenase; Male; Middle Aged; Mucins; Respiratory Mucosa; Young Adult

2012
Lack of activity of 15-epi-lipoxin A₄ on FPR2/ALX and CysLT1 receptors in interleukin-8-driven human neutrophil function.
    Clinical and experimental immunology, 2013, Volume: 173, Issue:2

    Topics: Cell Movement; Cell Survival; Cells, Cultured; Cyclic AMP; Humans; Interleukin-8; Lipoxins; Neutrophil Activation; Neutrophils; Protein Binding; Receptors, Formyl Peptide; Receptors, Leukotriene; Receptors, Lipoxin; Signal Transduction

2013
Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation.
    American journal of respiratory cell and molecular biology, 2015, Volume: 52, Issue:2

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Humans; Interleukin-8; Lipopolysaccharides; Lipoxins; Lung Injury; Mice, Inbred C57BL; Pneumonia; Signal Transduction

2015
Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Gene Expression Regulation; Heptanoic Acids; Interleukin-1beta; Interleukin-4; Interleukin-6; Interleukin-8; Lipoxins; Male; Mice; Mice, Inbred BALB C; Myeloid Differentiation Factor 88; NF-kappa B; Ovalbumin; Receptors, Formyl Peptide; Signal Transduction; Toll-Like Receptor 2

2015
Gingival crevicular fluid interleukin-8 and lipoxin A4 levels of smokers and nonsmokers with different periodontal status: a cross-sectional study.
    Journal of periodontal research, 2016, Volume: 51, Issue:4

    Topics: Adult; Cross-Sectional Studies; Female; Gingival Crevicular Fluid; Humans; Interleukin-8; Lipoxins; Male; Periodontal Diseases; Periodontal Index; Smokers; Smoking

2016