lipoxin a4 has been researched along with Inflammation in 152 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.66) | 18.7374 |
| 1990's | 6 (3.95) | 18.2507 |
| 2000's | 33 (21.71) | 29.6817 |
| 2010's | 90 (59.21) | 24.3611 |
| 2020's | 22 (14.47) | 2.80 |
| Authors | Studies |
|---|---|
| Brady, HR; Fiore, S; Maddox, JF; Petasis, NA; Serhan, CN; Takano, T | 1 |
| Brennan, E; Butler, E; Cacace, A; Chen, J; de Gaetano, M; Fallon, P; Gahan, K; Godson, C; Guiry, PJ; Hams, E; Leroy, X; Loscher, CE; Maingot, C; Marai, M; McLoughlin, A; Perretti, M; Zanetti, A | 1 |
| Ge, Y; Han, M; Lai, S; Zhao, J; Zhou, X | 1 |
| Das, UN | 4 |
| Chen, B; Hu, X; Mei, HX; Pan, WH; Xu, QC | 1 |
| AlaEddine, M; Authier, H; Bernad, J; Bouschbacher, M; Coste, A; Dardenne, C; Lefèvre, L; Meunier, E; Pipy, B; Salon, M | 1 |
| Assunção, N; Bozza, FA; Canetti, CA; Castro-Faria-Neto, HC; Chauvet, MG; Coutinho, G; Drummond, C; Ferreira, ST; Isaac, AR; Karmirian, K; Ledur, PF; Leo, LM; Lourenco, MV; Mattos, P; Moraes, CA; Ornelas, IM; Pamplona, FA; Paulsen, B; Rehen, SK; Ribeiro, FC; Sudo, FK; Tovar-Moll, F; Vanderborght, B; Vitória, G | 1 |
| Bai, JB; Chen, JH; Chen, QH; Ding, XY; He, XR; Hong, YH; Huang, ZX; Lan, JF; Lei, YH; Lin, DC | 1 |
| Chen, S; Dai, X; Dong, J; Feng, F; Huang, X; Li, D; Liao, E; Liao, J; Shao, Y | 1 |
| Chen, Y; Guo, X; Xia, H; Xu, L; You, CG; Zhao, M; Zhong, X; Zhou, Y | 1 |
| Lin, J; Luan, J; Peng, X; Wang, Q; Zhang, Y; Zhao, G; Zhu, X | 1 |
| Anfossi, R; Catalán, M; Díaz-Araya, G; González-Herrera, F; Gutiérrez-Figueroa, R; Maya, JD; Vivar, R | 1 |
| Fedulov, AV; Ramar, M; Yano, N | 1 |
| Bazan, HEP; Do, KV; He, J; Kakazu, AH; Pham, TL; Ponnath, A | 1 |
| Caramelli, P; Carvalho, MDG; de Sousa, LP; de Souza, LC; Ferreira, CN; Fraga, VG; Gomes, KB; Guimarães, HC; Loures, CMG; Magalhães, CA; Zauli, DAG | 1 |
| Alvarez, AM; Cadavid J, AP; Gil-Villa, AM; Rojas-López, M; Velásquez-Berrío, M | 1 |
| Kleniewska, P; Pawliczak, R; Szymczak-Pajor, I; Wieczfinska, J | 1 |
| Li, J; Liu, J; Peng, L | 1 |
| Akgül, Ö; Özdemir, AT; Özgül Özdemir, RB; Soysal Gündüz, Ö | 1 |
| Chen, BW; Chen, SQ; Fu, CC; Fu, XQ; He, MZ; Li, PJ; Lin, ZL; Yu, BY; Zheng, YH; Zhu, JH; Zhu, JJ | 1 |
| Bai, C; Chai, L; Deng, P; Jia, Y; Li, J; Liu, C; Sun, Q; Zhao, X; Zheng, C | 1 |
| Dias, IHK; Griffiths, HR | 1 |
| Croze, RH; Fang, X; Gotts, JE; Matthay, MA; Siegel, ER | 1 |
| Chiurchiù, V; de Vries, HE; Derada Troletti, C; Engelhardt, B; Enzmann, G; Jahromi, NH; Kamermans, A; Kooij, G; Leuti, A; Norris, PC; Schouten, M; Serhan, CN; Tietz, SM; van der Pol, SMA | 1 |
| He, H; Lin, J; Peng, X; Zhang, Y; Zhao, G; Zhu, X | 1 |
| Chan, ST; Lau, SN; Lim, R; Mockler, JC; Muljadi, R; Tan, JL; Tan, YZ; Wallace, EM | 1 |
| Feng, X; Koliwad, SK; Lutrin, D; Maze, M; Uchida, Y; Valdearcos, M | 1 |
| Alexander, JC; Candelario-Jalil, E; de Leon, LG; DeMars, KM; Febo, M; Frankowski, JC; Garrett, TJ; Graves, C; Hawkins, KE; McCrea, AO; Pacheco, SC; Yang, C | 1 |
| Aloia, T; Cata, JP; Conrad, C; Gottumukkala, V; Kim, BJ; Ramirez, MF; Vauthey, JN; Velasquez, JF | 1 |
| Aytan, N; Benincasa, C; Carreras, I; Crabtree, L; Dedeoglu, A; Jenkins, BG; Kantarci, A; Palaska, I; Stephens, D | 1 |
| Guo, YP; Jiang, H; Jiang, HK; Li, L; Tian, HY | 1 |
| Colas, RA; Dalli, J; De Maeyer, RP; Flint, JD; George, MJ; Gilroy, DW; Motwani, MP; Richard-Loendt, A; Serhan, CN | 1 |
| Ellett, F; Feng, Y; Lee, JA; Levy, BD; Loynes, CA; Renshaw, SA; Robertson, AL; Steel, MJ; Whyte, MKB | 1 |
| Ali-Shah, ST; Barry, M; Belton, O; Beuscart, O; Brennan, EP; Cooper, ME; Crean, D; Dai, A; de Gaetano, M; Derouiche, S; Dowdall, JF; Godson, C; Godson-Treacy, M; Gray, SP; Guiry, PJ; Jandeleit-Dahm, K; Kantharidis, P; Marai, M; McClelland, A; Mohan, M; Pickering, R; Sheehan, S; Tan, SM; Tikellis, C | 1 |
| da Silva, RF; da-Palma-Cruz, M; de Oliveira, APL; Grabulosa, CC; Lino-Dos-Santos-Franco, A; Monteiro, D; Rehim, HMMA | 1 |
| Jiang, W; Niu, F; Wang, A; Xie, H; Xu, T; Zhang, H; Zhang, J | 1 |
| Bielenberg, DR; Gartung, A; Gilligan, MM; Huang, S; Kieran, MW; Norris, PC; Panigrahy, D; Serhan, CN; Sukhatme, VP; Sulciner, ML | 1 |
| Guo, Z; He, J; He, Z; Hu, Q; Li, X; Liang, Y; Liu, H; Liu, L; Sun, X; Zhang, P; Zhang, Z; Zhao, J | 1 |
| Gong, H; Huang, W; Li, X; Liang, S | 1 |
| Barnig, C; Levy, BD | 2 |
| Braegger, C; Hersberger, M; Klinke, G; Rogler, D; Troxler, H; Weiss, GA | 1 |
| Deng, J; Liu, X; Qin, Z; Qu, L; Wang, C; Wang, H; Zhang, G | 1 |
| Jiang, S; Ni, SZ; Xia, J; Zhao, Y; Zhou, XL; Zhu, YQ | 1 |
| Bolstad, AI; Hasturk, H; Kantarci, A; Lygre, H; Mustafa, K; Mustafa, M; Serhan, C; Van Dyke, TE; Zarrough, A | 1 |
| Du, J; Hu, X; Qiu, H; Shao, L; Wu, G; Xia, J; Zhao, Q | 1 |
| Andersson, R; Chen, B; Kong, H; Lv, C; Lv, W; Sun, H; Xie, J; Xu, D; Yang, Y; Yu, S; Zhou, M | 1 |
| Abdelhamid, Ael-D; Abdelmoaty, S; Bas, DB; Brodin, E; Codeluppi, S; El-Awady, el-S; Fernandez-Zafra, T; Moustafa, Y; Svensson, CI; Wigerblad, G | 1 |
| Bancos, S; Phipps, RP; Ramon, S; Serhan, CN | 1 |
| Boscá, L; de la Cruz, A; Macías, Á; Moreno, C; Pimentel-Santillana, M; Prieto, P; Través, PG; Valenzuela, C | 1 |
| Liu, R; Shang, Y; Wan, Z; Wang, Z; Wu, Y; Yang, D; Yao, C; Yao, S; Yuan, S | 1 |
| Ballesteros, I; Corbí, A; Cuartero, MI; de la Parra, J; Hamilton, JA; Lizasoain, I; Moro, MA; Nombela, F; Pérez-Ruiz, A; Pradillo, JM; Ricote, M; Sobrado, M; Vivancos, J | 1 |
| Cho, H; Hamza, B; Irimia, D; Martel, J; Patel, S; Wong, E | 1 |
| Cai, ZY; Huang, YH; Wang, HM; Xu, FY; Zhou, XY | 1 |
| Cortés-Toro, V; Eriksdotter, M; Eyjolfsdottir, H; Fitzgerald, JM; Graff, C; Granholm, AC; Hjorth, E; Nennesmo, I; Palmblad, J; Sambamurti, K; Schultzberg, M; Serhan, CN; Wang, X; Zhu, M | 1 |
| Chen, H; Cheng, Q; Cheng, X; Huang, Y; Li, Y; Liu, H; Peng, H; Wu, P; Ye, D; Zeng, P; Zhang, D | 1 |
| Afonso, J; Albino-Teixeira, A; Bettencourt, P; Carvalho, F; Carvalho, J; Reina-Couto, M; Sousa, T; Vale, L; Valente, MJ | 1 |
| Buchanan, PJ; Clarke, DT; Harvey, BJ; Linnane, B; McDermott, M; McNally, P; Millar, RG; Ringholz, FC; Urbach, V | 1 |
| Arai, H; Arita, M; Imoto, Y; Isobe, Y; Segi-Nishida, E; Sugimoto, Y; Tani, Y | 1 |
| Awji, EG; Bruse, S; Chand, H; Colby, JK; Levy, BD; Mebratu, Y; Smith, KR; Tesfaigzi, Y | 1 |
| Andersson, R; Chen, B; Jin, Y; Sun, H; Wang, W; Xie, J; Xie, Y; Xu, D; Yang, F; Zhou, M | 1 |
| Águas, AP; Amaral, IF; Barbosa, JN; Barbosa, MA; Costa, M; Vasconcelos, DP | 1 |
| Haworth, O; Karra, L; Levi-Schaffer, F; Levy, BD; Priluck, R | 1 |
| Hou, Y; Yan, CL; Zhang, J | 1 |
| Awale, R; Huang, LL; Su, S; Tang, H; Zhang, XY; Zhong, LL | 1 |
| Buchanan, P; Higgins, G; McNally, P; Ringholz, F; Urbach, V | 1 |
| Cianci, E; Recchiuti, A; Romano, M; Simiele, F | 1 |
| Ali-Shah, ST; Börgeson, E; Colas, RA; Dalli, J; Godson, C; Guiry, PJ; Johnson, AM; Lee, YS; Serhan, CN; Sharma, K; Syed, GH; Till, A | 1 |
| Hasturk, H; Herrera, BS; Kantarci, A; Leung, KP; Van Dyke, TE; Zarrough, A | 1 |
| Amrani, Y; Bradding, P; Feghali-Bostwick, CA; Roach, KM | 1 |
| Bannenberg, G; Boscá, L; Cuadrado, A; Fernández-Velasco, M; López-Collazo, E; Martín-Sanz, P; Prieto, P; Rosales-Mendoza, CE; Terrón, V; Toledano, V | 1 |
| Carr, AJ; Dakin, SG; Dean, BJ; Martinez, FO; Oppermann, U; Roche, L; Smith, RD; Watkins, B; Wells, G; Wheway, K; Yapp, C | 1 |
| Chatterjee, S; Das, PN; Pedruzzi, G; Rao, KV | 1 |
| de Bruin, N; Ferreirós, N; Geisslinger, G; Homann, J; Schmidt, M; Scholich, K; Suo, J | 1 |
| Bian, XW; Chen, K; Li, L; Su, S; Wang, JM; Xiang, Y; Yoshimura, T; Zhu, J | 1 |
| Guo, Z; Guo, ZN; He, Y; Hu, Q; Ou, Y; Sun, X; Tang, J; Xu, L; Yin, C; Zhang, JH | 1 |
| Cheng, X; Gao, H; He, S; Li, Y; Miao, S; Peng, W; Wu, P; Yuan, J; Zhang, J | 1 |
| Bento, AF; Berta, T; Chen, G; Forner, S; Ji, RR; Martini, AC; Rae, GA | 1 |
| Baker, OJ; Melvin, JE; Wang, CS; Wee, Y; Yang, CH | 1 |
| Codagnone, M; Patruno, S; Pierdomenico, AM; Plebani, R; Recchiuti, A; Romano, M; Simiele, F | 1 |
| Chandrasekharan, JA; Huang, XM; Hwang, AC; Sharma-Walia, N | 1 |
| Bruni, P; Cianci, E; Croce, F; Diomede, F; Merciaro, I; Meschini, I; Romano, M; Trubiani, O | 1 |
| Bahl, CD; Bomberger, JM; Eddens, T; Flitter, BA; Hammock, BD; Hampton, TH; Hvorecny, KL; Kolls, JK; Kwak, DH; Lee, JS; Levy, BD; Liu, X; Madden, DR; Morisseau, C; Ono, E; Yang, J | 1 |
| Blumberg, N; Lannan, KL; Phipps, RP; Spinelli, SL | 1 |
| Cernadas, M; Haworth, O; Levy, BD; Serhan, CN; Yang, R | 1 |
| Chen, ZQ; Dong, L; Liao, PY; Wu, SH | 1 |
| D'Acquisto, F; Perretti, M | 2 |
| Billen, F; Cambier, C; Chandler, T; Clercx, C; Gustin, P; Kirschvink, N; Leemans, J | 1 |
| Antczak, A; Kuna, P; Kupczyk, M; Kuprys-Lipinska, I | 1 |
| Li, G; Sun, L; Wu, P; Xu, Y; Ye, D; Yu, Y; Zhu, L | 1 |
| Cripps, MW; Cureton, EL; Curran, B; Dua, MM; Ereso, AQ; Sadjadi, J; Victorino, GP | 1 |
| Bellingan, G; Colville-Nash, P; de Souza, P; Gilroy, DW; Hobbs, A; Morris, T; Newson, J; Stables, M; Warner, T | 1 |
| Arita, M; Azuma, T; Fujita, T; Ishida, T; Kure, I; Kutsumi, H; Mizuno, M; Nishitani, Y; Nishiumi, S; Tanoue, T; Yoshida, M | 1 |
| Barja-Fidalgo, C; da-Fé, AR; Fierro, IM; Niconi-de-Almeida, Y; Simões, RL | 1 |
| Dong, B; Gronert, K; Lau, D; Leedom, AJ; Sullivan, AB | 1 |
| Dong, L; Liu, B; Wu, HJ; Wu, SH | 1 |
| Brancaleone, V; Buckingham, JC; D'Acquisto, F; Dalli, J; Dufton, N; Flower, RJ; Gray, M; Hannon, R; Patel, HB; Perretti, M | 1 |
| Croze, R; Levy, BD; Pfeffer, MA; Planagumà, A; Rubin, G; Serhan, CN; Uddin, M | 1 |
| Bellingan, G; Colville-Nash, P; de Souza, PM; Gilroy, DW; Morris, T; Newson, J; Stables, M | 1 |
| Chan, MM; Moore, AR | 1 |
| Huang, B; Huang, C; Jia, H; Jiang, T; Li, D; Liu, J; Ma, J; Shen, GX; Tang, K; Yang, Z; Ye, D; Zhang, B | 1 |
| Serhan, CN; Spite, M | 1 |
| Chen, H; Furue, M; Moroi, Y; Nakahara, T; Takahara, M; Takeuchi, S; Tu, Y; Uchi, H; Xie, L | 1 |
| Bena, S; Brancaleone, V; Cirino, G; Dalli, J; Flower, RJ; Perretti, M | 1 |
| Flower, RJ; Norling, LV; Perretti, M; Serhan, CN; Spite, M; Yang, R | 1 |
| Min, Z; Wang, A; Wu, J; Xiong, Y; Xu, J; Yan, Q; Zhang, J; Zhang, S | 1 |
| Andreasson, E; Dahlgren, C; Forsman, H; Önnheim, K | 1 |
| Dichter, E; Kerner, D; Lacorte, G; Rodriguez, A; Spur, B; Walker, J; Yin, K | 1 |
| Li, LY; Liu, RG; Shang, Y; Wang, YP; Wu, Y; Yao, SL; Yuan, SY; Zheng, J; Zhou, JP | 1 |
| Abayasekara, DR; Dakin, SG; Dudhia, J; Hibbert, A; Smith, RK; Werling, D; Young, NJ | 1 |
| Börgeson, E; Corrigan, N; Godson, C; Harford, KA; Higgins, DF; Maderna, P; McGillicuddy, FC; Roche, HM | 1 |
| Cianci, E; Florio, G; Gangemi, S; Lattanzio, S; Patella, V; Romano, M; Saitta, S | 1 |
| Chen, Z; Huang, C; Li, S; Lu, X; Mao, L; Wu, Z; Zhao, Y; Zhou, X; Zhou, Y | 1 |
| Bellocchio, L; Bellochio, L; Bento, AF; Calixto, JB; Canetti, C; Duarte, FS; Ferreira, J; Forner, S; Guimarães, MZ; Lerner, R; Lutz, B; Marsicano, G; Matias, I; Menezes de Lima, O; Monory, K; Pamplona, FA; Takahashi, RN; Villarinho, JG; Wotjak, CT | 1 |
| Abayasekara, DR; Dakin, SG; Dudhia, J; Smith, RK; Werling, D; Werling, NJ | 1 |
| Dalli, J; Dimisko, L; Irimia, D; Jones, CN; Serhan, CN; Wong, E | 1 |
| Britton, SL; Chawla, A; Feng, X; Koch, LG; Matthay, MA; Maze, M; Su, X; Terrando, N; Yan, Y | 1 |
| Asadullah, K; Bauman, J; Colgan, SP; Fierro, IM; Giesen, C; Guilford, W; Parkinson, JF; Perez, HD; Schottelius, AJ | 1 |
| Serhan, CN; Van Dyke, TE | 1 |
| Brady, HR; Godson, C; Lappin, D; Mitchell, S; Stenson, C | 1 |
| Arita, M; Bannenberg, G; Devchand, PR; Gronert, K; Hong, S; Moussignac, RL; Serhan, CN | 1 |
| Ackerman, K; De Sanctis, GT; Devchand, PR; Drazen, JM; Kim, E; Levy, BD; Schmidt, B; Serhan, CN; Szczeklik, W | 1 |
| Levy, B; Serhan, CN | 1 |
| Cooper, D; Gilroy, DW; Moradi-Bidhendi, N; Paul-Clark, MJ; Van Cao, T | 1 |
| Bannenberg, G; Bauman, JG; Devchand, PR; Gronert, K; Guilford, WJ; Moussignac, RL; Parkinson, JF; Perez, HD; Schmidt, BA; Serhan, CN; Subramanyam, B | 1 |
| Serhan, CN | 2 |
| Cooper, AM; Karp, CL | 1 |
| Aliberti, J; Bafica, A; Dias, A; Esper, L; Johndrow, JE; Machado, FS; Serhan, CN | 1 |
| Brounts, L; Harms, B; Heise, C; Mangino, MJ | 1 |
| Romano, M | 1 |
| Schwab, JM; Serhan, CN | 1 |
| Gilroy, DW; Morris, T; Rajakariar, R; Stables, M | 1 |
| Endo, H; Hashimoto, A; Hayashi, I; Kitasato, H; Murakami, Y | 1 |
| Serhan, CN; Svensson, CI; Zattoni, M | 1 |
| Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Jiang, X; Karlsson, L; Lundeen, KA; Rao, NL; Riley, JP; Williams, KN; Xue, X | 1 |
| Amaral, FA; Cisalpino, D; Fagundes, CT; Fierro, IM; Nicoli, JR; Pinho, V; Sousa, LP; Souza, DG; Teixeira, MM; Vieira, AT; Vieira, LQ | 1 |
| Hopkinson, P; Lipworth, BJ; Meldrum, KT; Menzies, D; Nair, A | 1 |
| Dudhane, A; Godfrey, HP; Lin, KT; Wong, PY | 1 |
| Brady, HR; Papayianni, A; Serhan, CN | 1 |
| Hachicha, M; Petasis, NA; Pouliot, M; Serhan, CN | 1 |
| Clish, CB; Gronert, K; Serhan, CN | 1 |
| Chiang, N; Clish, CB; Levy, BD; Serhan, CN; Tai, HH | 1 |
| Chiang, N; Gronert, K; Martinsson-Niskanen, T; Ravasi, S; Serhan, CN | 1 |
| Fierro, IM; Serhan, CN | 1 |
| Dahlén, SE; Hedqvist, P; Palmertz, U; Raud, J | 1 |
| Dahlén, SE; Hedqvist, P; Raud, J | 1 |
| Dahlén, SE; Haeggström, J; Hedqvist, P; Nicolaou, KC; Palmertz, U; Raud, J | 1 |
18 review(s) available for lipoxin a4 and Inflammation
| Article | Year |
|---|---|
Essential Fatty Acids and Their Metabolites in the Pathobiology of Inflammation and Its Resolution.
Topics: Animals; COVID-19; Dinoprostone; Fatty Acids, Essential; Humans; Inflammation; Leukotriene B4; Lipoxins; SARS-CoV-2 | 2021 |
Innate immunity is a key factor for the resolution of inflammation in asthma.
Topics: Asthma; Eosinophils; Humans; Immunity, Innate; Inflammation; Killer Cells, Natural; Lipoxins | 2015 |
Physiological impact of abnormal lipoxin A₄ production on cystic fibrosis airway epithelium and therapeutic potential.
Topics: Adenosine Triphosphate; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Inflammation; Lipoxins; Lung; Respiratory Mucosa; Signal Transduction | 2015 |
Lipoxins and aspirin-triggered lipoxins in resolution of inflammation.
Topics: Animals; Aspirin; Humans; Inflammation; Inflammation Mediators; Lipoxins; Signal Transduction | 2015 |
New development in studies of formyl-peptide receptors: critical roles in host defense.
Topics: Animals; Cell Movement; Chemotaxis; Humans; Inflammation; Leukocytes; Lipoxins; Macrophages; Neoplasms; Receptors, CCR7; Receptors, Formyl Peptide; Receptors, Interleukin-8B; Wound Healing | 2016 |
Annexin A1 and glucocorticoids as effectors of the resolution of inflammation.
Topics: Animals; Annexin A1; Anti-Inflammatory Agents; Circadian Rhythm; Gene Expression Regulation; Glucocorticoids; Humans; Hydrocortisone; Immune System; Immunity, Innate; Inflammation; Lipoxins; Macrophages; Mice; Mice, Knockout; Models, Immunological; Monocytes; Neutrophils; Receptors, Formyl Peptide; Receptors, Lipoxin; T-Lymphocyte Subsets | 2009 |
Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2; Fatty Acids, Omega-3; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Lipid Metabolism; Lipoxins | 2010 |
Arachidonic acid and lipoxin A4 as possible endogenous anti-diabetic molecules.
Topics: Animals; Arachidonic Acid; Brain-Derived Neurotrophic Factor; Diabetes Mellitus; Fatty Acids, Unsaturated; Humans; Hypothalamus; Inflammation; Inflammation Mediators; Lipid Metabolism; Lipoxins; Obesity; Receptors, G-Protein-Coupled; Signal Transduction | 2013 |
Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 15-Lipoxygenase; Aspirin; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Inflammation Mediators; Leukotrienes; Lipoxins; Neutrophil Activation; Neutrophils; Periodontitis; Prostaglandins | 2003 |
Biphasic regulation of leukocyte trafficking by lipoxins.
Topics: Apoptosis; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Kinetics; Leukocytes; Lipoxins; Neutrophils; Phagocytes; Signal Transduction | 2002 |
Novel pathways and endogenous mediators in anti-inflammation and resolution.
Topics: Animals; Arachidonate 5-Lipoxygenase; Aspirin; Cell Communication; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene A4; Lipoxins; Prostaglandins | 2003 |
Clues for new therapeutics in osteoporosis and periodontal disease: new roles for lipoxygenases?
Topics: Animals; Animals, Genetically Modified; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arteriosclerosis; Bone Remodeling; Eicosanoids; Enzyme Induction; Humans; Inflammation; Inflammation Mediators; Lipoxins; Lipoxygenase Inhibitors; Mice; Osteoporosis; Osteoporosis, Postmenopausal; Periodontitis; Rabbits; Recombinant Fusion Proteins | 2004 |
Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.
Topics: Acetylation; Animals; Anti-Inflammatory Agents; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lipoxins; Periodontitis | 2006 |
Novel aspects of annexin 1 and glucocorticoid biology: intersection with nitric oxide and the lipoxin receptor.
Topics: Animals; Annexin A1; Anti-Inflammatory Agents; Gene Expression Regulation; Glucocorticoids; Humans; Inflammation; Lipoxins; Nitric Oxide; Nitric Oxide Donors; Prednisolone; Receptors, Formyl Peptide; Receptors, Glucocorticoid; Receptors, Lipoxin | 2006 |
Lipoxins and new lipid mediators in the resolution of inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Humans; Inflammation; Lipid Metabolism; Lipoxins; Signal Transduction | 2006 |
Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Autacoids; Cytokines; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Inflammation Mediators; Lipids; Lipoxins; Lipoxygenase | 2001 |
Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side.
Topics: Animals; Arachidonate 5-Lipoxygenase; Aspirin; Eicosanoids; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Lipoxins; Neutrophils; Receptors, Leukotriene B4; Signal Transduction | 2001 |
Microvascular actions of eicosanoids in the hamster cheek pouch.
Topics: Animals; Antigens; Cheek; Cricetinae; Dinoprostone; Eicosanoids; Epoprostenol; Hydroxyeicosatetraenoic Acids; Inflammation; Leukocytes; Lipoxins; Microcirculation | 1990 |
4 trial(s) available for lipoxin a4 and Inflammation
| Article | Year |
|---|---|
Inflammation and pro-resolution inflammation after hepatobiliary surgery.
Topics: Aged; Anti-Inflammatory Agents; Biliary Tract Surgical Procedures; Colorectal Neoplasms; Docosahexaenoic Acids; Female; Hepatectomy; Humans; Hydrocortisone; Inflammation; Interleukin-6; Lipoxins; Liver Neoplasms; Male; Middle Aged; Perioperative Period; Postoperative Complications; Prognosis; Time Factors; Treatment Outcome | 2017 |
Effects of low-dose aspirin on acute inflammatory responses in humans.
Topics: Acute Disease; Aspirin; Blister; Cantharidin; Cell Adhesion; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; Inflammation; Lipoxins; Macrophages; Male; Nitric Oxide; Receptors, Formyl Peptide; Receptors, Lipoxin; Up-Regulation | 2009 |
Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways.
Topics: Adult; Aspirin; Humans; Inflammation; Lipoxins; Male; Middle Aged; Receptors, Formyl Peptide; Receptors, Lipoxin; Time Factors | 2010 |
Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Breath Tests; Bronchial Provocation Tests; Double-Blind Method; Female; Humans; Inflammation; Lipoxins; Lung; Male; Nitric Oxide; Placebos; Respiratory Function Tests; Thromboxane B2 | 2008 |
130 other study(ies) available for lipoxin a4 and Inflammation
| Article | Year |
|---|---|
Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; Chemotaxis, Leukocyte; CHO Cells; Cloning, Molecular; Cricetinae; Female; Guanosine Triphosphate; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Lipoxins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tissue Distribution | 1997 |
Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A
Topics: Animals; Cell Line; Humans; Imidazoles; Inflammation; Lipoxins; Mice; Molecular Mimicry; Monocytes; NF-kappa B; Oxazoles; Peritonitis; Receptors, Formyl Peptide | 2019 |
Changes of Lipoxin A4 and the Anti-inflammatory Role During Parturition.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Epinephrine; Female; Humans; Inflammation; Lipoxins; Mice; Parturition; Pregnancy | 2022 |
The Effect and Mechanism of Lipoxin A4 on Neutrophil Function in LPS-Induced Lung Injury.
Topics: Animals; Inflammation; Lipopolysaccharides; Lipoxins; Lung Injury; Neutrophils; Rats; Reactive Oxygen Species; Receptors, Lipoxin; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha | 2022 |
Topical Aspirin Administration Improves Cutaneous Wound Healing in Diabetic Mice Through a Phenotypic Switch of Wound Macrophages Toward an Anti-inflammatory and Proresolutive Profile Characterized by LXA4 Release.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Diabetes Mellitus, Experimental; Inflammation; Leukotriene A4; Leukotriene B4; Lipoxins; Macrophages; Mice; Phenotype; Skin; Wound Healing | 2022 |
Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans.
Topics: Aged; Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Cytokines; Endocannabinoids; Humans; Inflammation; Inflammation Mediators; Lipoxins; Mice | 2022 |
Lipoxin A4 depresses inflammation and promotes autophagy via AhR/mTOR/AKT pathway to suppress endometriosis.
Topics: Animals; Autophagy; Endometriosis; Endometrium; Female; Humans; Inflammation; Lipoxins; Mice; Proto-Oncogene Proteins c-akt; Receptors, Aryl Hydrocarbon; TOR Serine-Threonine Kinases | 2023 |
Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair.
Topics: Animals; Anti-Inflammatory Agents; Exosomes; Extraembryonic Membranes; Female; Humans; Inflammation; Lipopolysaccharides; Mice; Pregnancy; Receptors, Formyl Peptide; Receptors, Lipoxin | 2023 |
Lipoxin A4 attenuates MSU-crystal-induced NLRP3 inflammasome activation through suppressing Nrf2 thereby increasing TXNRD2.
Topics: Animals; Gout; Inflammasomes; Inflammation; Macrophages; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidoreductases; Rats; Reactive Oxygen Species; Thioredoxin Reductase 2; Uric Acid | 2022 |
Lipoxin A4 alleviates inflammation in
Topics: Aspergillus fumigatus; Epithelial Cells; Heme Oxygenase-1; Humans; Inflammation; Inflammation Mediators; NF-E2-Related Factor 2; Signal Transduction | 2022 |
Lipoxin A4 prevents high glucose-induced inflammatory response in cardiac fibroblast through FOXO1 inhibition.
Topics: Fibroblasts; Fibrosis; Forkhead Box Protein O1; Glucose; Humans; Inflammation; Lipoxins; NF-kappa B | 2023 |
Intra-Airway Treatment with Synthetic Lipoxin A4 and Resolvin E2 Mitigates Neonatal Asthma Triggered by Maternal Exposure to Environmental Particles.
Topics: Animals; Asthma; Female; Humans; Infant, Newborn; Inflammation; Maternal Exposure; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Vehicle Emissions | 2023 |
Lipoxin A4 (LXA4) Reduces Alkali-Induced Corneal Inflammation and Neovascularization and Upregulates a Repair Transcriptome.
Topics: Alkalies; Animals; Burns, Chemical; Corneal Opacity; Cytokines; Hyphema; Inflammation; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Transcriptome; Vascular Endothelial Growth Factor A | 2023 |
Inflammatory and Pro-resolving Mediators in Frontotemporal Dementia and Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Annexin A1; Cytokines; Diagnosis, Differential; Female; Frontotemporal Dementia; Genotype; Healthy Volunteers; Humans; Inflammation; Lipoxins; Male; Middle Aged | 2019 |
Role of aspirin-triggered lipoxin A4, aspirin, and salicylic acid in the modulation of the oxidative and inflammatory responses induced by plasma from women with pre-eclampsia.
Topics: Acetylation; Adolescent; Adult; Aspirin; Cell Adhesion; Cyclooxygenase 2; Female; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipoxins; Neutrophils; NF-kappa B; Oxidative Stress; Pre-Eclampsia; Pregnancy; Protein Processing, Post-Translational; Salicylic Acid; Thiobarbituric Acid Reactive Substances; Tyrosine; U937 Cells; Young Adult | 2020 |
Wide-Range Effects of 1,25(OH)2D3 on Group 4A Phospholipases Is Related to Nuclear Factor κ-B and Phospholipase-A2 Activating Protein Activity in Mast Cells.
Topics: Asthma; Cell Line, Transformed; Cholecalciferol; Gene Expression Regulation; Humans; Inflammation; Lipoxins; Mast Cells; NF-kappa B; Phospholipases A2; Signal Transduction; Ubiquitination | 2020 |
The Lipoxin A4 Receptor Agonist BML-111 Alleviates Inflammatory Injury and Oxidative Stress in Spinal Cord Injury.
Topics: Animals; Apoptosis; Heptanoic Acids; Inflammation; Interleukin-1beta; Interleukin-6; Lipoxins; Male; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Receptors, Lipoxin; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2020 |
Low levels of pro-resolving lipid mediators lipoxin-A4, resolvin-D1 and resolvin-E1 in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cytokines; Disease Progression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Inflammation; Inflammation Mediators; Lipid Metabolism; Lipoxins; Male; Middle Aged | 2020 |
LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IκB/NF-κB pathway.
Topics: Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Blood-Brain Barrier; Brain Edema; Brain Injuries; Disease Models, Animal; Hypoxia; Hypoxia-Ischemia, Brain; I-kappa B Proteins; Inflammation; Injections, Intraventricular; Lipoxins; Male; Neurons; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Lipoxin A4-Mediated p38 MAPK Signaling Pathway Protects Mice Against Collagen-Induced Arthritis.
Topics: Animals; Anisomycin; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Proliferation; Collagen; Female; Imidazoles; Inflammation; Lipoxins; MAP Kinase Signaling System; Mice; Mice, Inbred DBA; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Synovial Membrane | 2021 |
Current and Future Directions for Targeting Lipoxin A4 in Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Brain; Humans; Inflammation; Inflammation Mediators; Lipoxins | 2021 |
Inhibition of the lipoxin A4 and resolvin D1 receptor impairs host response to acute lung injury caused by pneumococcal pneumonia in mice.
Topics: Acute Lung Injury; Animals; Docosahexaenoic Acids; Humans; Inflammation; Lipoxins; Lung; Mice; Permeability; Pneumonia, Pneumococcal; Receptors, Lipoxin; Respiratory Distress Syndrome | 2021 |
Pro-resolving lipid mediator lipoxin A
Topics: Adult; Animals; Brain; Cell Movement; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Inflammation; Lipidomics; Lipoxins; Mice, Inbred C57BL; Multiple Sclerosis; Spinal Cord; T-Lymphocytes; Th1 Cells; Th17 Cells | 2021 |
Lipoxin A4 activates ALX/FPR2 to attenuate inflammation in Aspergillus fumigatus keratitis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Aspergillosis; Aspergillus fumigatus; Cornea; Cytokines; Eye Infections, Fungal; Female; Inflammation; Keratitis; Lipoxins; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; RAW 264.7 Cells; Receptors, Formyl Peptide | 2021 |
Amnion Epithelial Cells Promote Lung Repair via Lipoxin A
Topics: Amnion; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Cytokines; Epithelial Cells; Humans; Inflammation; Lipoxins; Lung; Macrophages; Mice, Inbred C57BL; Neutrophils; Peroxidase; Phagocytosis | 2017 |
Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cognitive Dysfunction; Disease Models, Animal; Fear; Hippocampus; Inflammation; Lipoxins; Male; Mice; Mice, Inbred C57BL; Microglia; Neurons; Organic Chemicals; Postoperative Complications; Receptors, CCR2; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Signal Transduction; Tibial Fractures | 2017 |
Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Disease Models, Animal; Heptanoic Acids; Infarction, Middle Cerebral Artery; Inflammation; Lipoxins; Male; Microglia; Protective Factors; Rats; Rats, Sprague-Dawley; Recovery of Function; Stroke; Time | 2017 |
Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Therapy, Combination; Eicosapentaenoic Acid; Female; Hippocampus; Inflammation; Lipoxins; Mice; Mice, Transgenic | 2018 |
Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation.
Topics: Animals; Body Weight; Diet, High-Fat; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Inflammation; Injections, Intraperitoneal; Kidney Diseases; Kidney Glomerulus; Lipoxins; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Obesity; p38 Mitogen-Activated Protein Kinases; Risk Factors | 2018 |
Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Anti-Inflammatory Agents; Blister; Chemokines; Cytokines; Docosahexaenoic Acids; Eicosanoids; Eicosapentaenoic Acid; Escherichia coli; Humans; Inflammation; Leukocytes; Lipoxins; Male; Middle Aged; Neutrophils; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, G-Protein-Coupled; Receptors, Lipoxin; Skin; Volunteers; Young Adult | 2018 |
PGE
Topics: Animals; Animals, Genetically Modified; Cell Movement; Dinoprostone; Disease Models, Animal; Inflammation; Lipoxins; Lipoxygenases; Macrophages; Neutrophils; Phenotype; Receptors, Prostaglandin E, EP4 Subtype; Wounds and Injuries; Zebrafish | 2018 |
Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Atherosclerosis; Chemokine CCL2; Cytokines; Diabetes Mellitus, Experimental; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipoxins; Mice; Vascular Cell Adhesion Molecule-1 | 2018 |
Photobiomodulation modulates the resolution of inflammation during acute lung injury induced by sepsis.
Topics: Acute Lung Injury; Animals; Bone Marrow; Bronchoalveolar Lavage; Cell Movement; Cholinergic Agents; Cytokines; Eicosapentaenoic Acid; Inflammation; Lipopolysaccharides; Lipoxins; Low-Level Light Therapy; Lung; Male; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Sepsis | 2019 |
Is lipoxin A4 an effective treatment on fat embolism syndrome by attenuating pro-inflammatory response?
Topics: Animals; Embolism, Fat; Fatty Acids, Nonesterified; Humans; Inflammation; Lipoxins; Male; Rats; Rats, Sprague-Dawley; Receptors, Formyl Peptide; Receptors, Lipoxin; Signal Transduction; Wound Healing | 2019 |
Aspirin-triggered proresolving mediators stimulate resolution in cancer.
Topics: Animals; Antineoplastic Agents; Aspirin; Chemokine CCL2; Chemokines; Cytokines; Disease Models, Animal; Docosahexaenoic Acids; Eicosanoids; Fatty Acids, Unsaturated; Female; Inflammation; Lipoxins; Macrophages; Metabolomics; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neoplasm Metastasis; Neoplasms; Nerve Tissue Proteins; Phagocytosis; Plasminogen Inactivators; Prostaglandins | 2019 |
LXA4 ameliorates cerebrovascular endothelial dysfunction by reducing acute inflammation after subarachnoid hemorrhage in rats.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebral Cortex; Cytokines; Endothelial Cells; Endothelium, Vascular; Inflammation; Lipoxins; Male; Rats; Rats, Sprague-Dawley; Signal Transduction; Subarachnoid Hemorrhage | 2019 |
[Change of serum myeloperoxidase and lipoxin A4 level in coronary heart disease patients with anxiety and/or depression].
Topics: Aged; Anxiety; Case-Control Studies; Coronary Disease; Depression; Female; Humans; Inflammation; Lipoxins; Male; Middle Aged; Peroxidase | 2013 |
Lipoxin A4: a new direction in asthma therapy?
Topics: Animals; Asthma; Humans; Inflammation; Lipoxins; Portraits as Topic; Respiratory System | 2013 |
High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactation.
Topics: Docosahexaenoic Acids; Eicosanoids; Eicosapentaenoic Acid; Female; Humans; Infant; Infant, Newborn; Inflammation; Lactation; Lipid Metabolism; Lipoxins; Milk, Human; United States | 2013 |
Resolution of PMA-induced skin inflammation involves interaction of IFN-γ and ALOX15.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Female; Fluorescent Antibody Technique; Inflammation; Interferon-gamma; Lipoxins; Male; Mice; Real-Time Polymerase Chain Reaction; Skin; Tetradecanoylphorbol Acetate | 2013 |
Roles of lipoxin A4 in preventing paracetamol-induced acute hepatic injury in a rabbit model.
Topics: Acetaminophen; Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Chemical and Drug Induced Liver Injury; Hepatocytes; Inflammation; Interleukin-10; Lipoxins; Liver; Male; Rabbits; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2013 |
Resolvin D1 protects periodontal ligament.
Topics: Anti-Inflammatory Agents; Cell Movement; Cell Proliferation; Cells, Cultured; Dinoprostone; Docosahexaenoic Acids; Fibroblasts; Humans; Inflammation; Interleukin-1beta; Lipoxins; Monocytes; Periodontal Ligament; Tumor Necrosis Factor-alpha; Up-Regulation; Wound Healing | 2013 |
Lipoxin a4 preconditioning and postconditioning protect myocardial ischemia/reperfusion injury in rats.
Topics: Animals; Arrhythmias, Cardiac; Connexin 43; Cytokines; Electrocardiography; Gene Expression Regulation; Inflammation; Ischemic Postconditioning; Ischemic Preconditioning; Lipoxins; Male; Malondialdehyde; Microscopy, Electron, Transmission; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Troponin I | 2013 |
Lipoxin A4 attenuation of endothelial inflammation response mimicking pancreatitis-induced lung injury.
Topics: Acute Lung Injury; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Chemokine CCL8; E-Selectin; eIF-2 Kinase; Endothelium, Vascular; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Lipoxins; Lung; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pancreatitis; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2013 |
Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anti-Inflammatory Agents; Astrocytes; Cells, Cultured; Cytokines; Docosahexaenoic Acids; Edema; Humans; Hypersensitivity; Inflammation; Interferon-gamma; Lipoxins; Male; Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Lipoxin; Spinal Cord; Tumor Necrosis Factor-alpha | 2013 |
Lipoxin A₄ modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism.
Topics: Adaptive Immunity; Adaptor Proteins, Signal Transducing; Animals; Antibodies; B-Lymphocytes; Cell Proliferation; Cells, Cultured; Down-Regulation; Humans; Immunoglobulin G; Immunoglobulin M; Immunologic Memory; Inflammation; Lipoxins; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Protein Transport; Receptors, Formyl Peptide; Receptors, Lipoxin; Signal Transduction; Up-Regulation | 2014 |
Modulation of voltage-dependent and inward rectifier potassium channels by 15-epi-lipoxin-A4 in activated murine macrophages: implications in innate immunity.
Topics: Animals; Apoptosis; Calcium; Gene Expression Regulation; Immunity, Innate; Inflammation; Interleukin-13; Interleukin-4; Ion Transport; Kv1.3 Potassium Channel; Kv1.5 Potassium Channel; Lipopolysaccharides; Lipoxins; Macrophage Activation; Mice; Mice, Inbred BALB C; Nerve Tissue Proteins; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Receptors, Formyl Peptide; RNA, Messenger; Scorpion Venoms; Specific Pathogen-Free Organisms; Up-Regulation | 2013 |
Aspirin-triggered lipoxin A4 attenuates lipopolysaccharide induced inflammatory response in primary astrocytes.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Aspirin; Astrocytes; Cells, Cultured; Cyclooxygenase 2; Inflammation; Lipopolysaccharides; Lipoxins; Neuroimmunomodulation; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Signal Transduction | 2014 |
Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways.
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain Ischemia; CD36 Antigens; Cells, Cultured; Hypoglycemic Agents; Inflammation; Lipoxins; Mice; Mice, Inbred C57BL; Neutrophils; Phagocytosis; PPAR gamma; Rats; Rosiglitazone; Thiazolidinediones; Up-Regulation | 2014 |
Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels.
Topics: Chemotaxis, Leukocyte; Cyclic N-Oxides; HL-60 Cells; Humans; Inflammation; Lipoxins; Microfluidics; Neutrophils; Spin Labels | 2014 |
Lipoxin A4 inhibits NF-κB activation and cell cycle progression in RAW264.7 cells.
Topics: Animals; Cell Cycle; Cell Line; Cell Proliferation; Cyclin E; Down-Regulation; Flow Cytometry; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Lipoxins; Macrophages; Mice; NF-kappa B; Protein Transport; Signal Transduction | 2014 |
Resolution of inflammation is altered in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Case-Control Studies; Cognitive Dysfunction; Docosahexaenoic Acids; Female; Hippocampus; Humans; Inflammation; Inflammation Mediators; Lipoxins; Lipoxygenase; Male; Middle Aged; Receptors, Formyl Peptide; Receptors, Lipoxin; tau Proteins | 2015 |
Glucocorticoids sensitize rat placental inflammatory responses via inhibiting lipoxin A4 biosynthesis.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line; Dexamethasone; Dinoprostone; Female; Glucocorticoids; Humans; Inflammation; Leukotriene B4; Lipopolysaccharides; Lipoxins; MAP Kinase Signaling System; NF-kappa B; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley | 2014 |
Impaired resolution of inflammation in human chronic heart failure.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Cardiovascular Diseases; Chronic Disease; Female; Glomerular Filtration Rate; Heart Failure; Humans; Inflammation; Leukocyte Count; Lipoxins; Male; Peroxidase; Risk Factors | 2014 |
Reduced 15-lipoxygenase 2 and lipoxin A4/leukotriene B4 ratio in children with cystic fibrosis.
Topics: Anti-Bacterial Agents; Arachidonate 15-Lipoxygenase; Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Inflammation; Leukotriene A4; Leukotriene B4; Lipoxins; Longitudinal Studies; Lung; Lung Diseases; Macrophages, Alveolar; Male; Neutrophils | 2014 |
Eosinophils control the resolution of inflammation and draining lymph node hypertrophy through the proresolving mediators and CXCL13 pathway in mice.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Cells, Cultured; Chemokine CXCL13; Eosinophils; Flow Cytometry; Hypertrophy; Inflammation; Lipoxins; Lymph Nodes; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microarray Analysis; Peritonitis | 2014 |
Wood smoke enhances cigarette smoke-induced inflammation by inducing the aryl hydrocarbon receptor repressor in airway epithelial cells.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Line; Chemokines; Cyclooxygenase 2; Dinoprostone; Epithelial Cells; Humans; Inflammation; Intramolecular Oxidoreductases; Lipoxins; Lung; Male; Mice; Mice, Inbred C57BL; Neutrophils; Prostaglandin-E Synthases; Receptors, Aryl Hydrocarbon; Smoke; Smoking; Wood | 2015 |
Regional arterial infusion with lipoxin A4 attenuates experimental severe acute pancreatitis.
Topics: Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cytokines; Heme Oxygenase-1; Inflammation; Infusions, Intra-Arterial; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Lipoxins; Male; Pancreas; Pancreatitis; Peroxidase; Phospholipases A2; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Modulation of the inflammatory response to chitosan through M2 macrophage polarization using pro-resolution mediators.
Topics: Animals; Biomarkers; Cell Polarity; Chitosan; Cytokines; Decapodiformes; Docosahexaenoic Acids; Flow Cytometry; Implants, Experimental; Inflammation; Lipoxins; Macrophages; Male; Mice, Inbred BALB C | 2015 |
Lipoxin B₄ promotes the resolution of allergic inflammation in the upper and lower airways of mice.
Topics: Animals; Cell Degranulation; Chemotaxis, Leukocyte; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Inflammation; Leukocytes; Lipoxins; Lung; Male; Mast Cells; Mice; Mucus; Nasal Mucosa; Respiratory Hypersensitivity | 2015 |
Decreased plasma levels of lipoxin A4 in children with autism spectrum disorders.
Topics: Asian People; Autism Spectrum Disorder; Biomarkers; Child, Preschool; Cross-Sectional Studies; Female; Humans; Inflammation; Lipoxins; Male | 2015 |
Expression of anti-inflammatory mediator lipoxin A4 and inflammation responsive transcriptive factors NF-kappa B in patients with preeclampsia.
Topics: Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Humans; Immunohistochemistry; Inflammation; Lipoxins; Placenta; Pre-Eclampsia; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor RelA | 2014 |
Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Inflammation; Kidney; Kidney Diseases; Lipoxins; Liver; Liver Diseases; Mice, Inbred C57BL; Obesity | 2015 |
LXA4 actions direct fibroblast function and wound closure.
Topics: 3T3 Cells; Actins; Animals; Cell Differentiation; Cell Proliferation; Collagen Type I; Collagen Type III; Docosahexaenoic Acids; Fibroblasts; Inflammation; Lipoxins; Mice; Myofibroblasts; Receptors, Formyl Peptide; Transforming Growth Factor beta1; Wound Healing | 2015 |
Lipoxin A4 Attenuates Constitutive and TGF-β1-Dependent Profibrotic Activity in Human Lung Myofibroblasts.
Topics: Actins; Cell Proliferation; Cells, Cultured; Collagen; Enzyme Activation; Humans; Idiopathic Pulmonary Fibrosis; Inflammation; Lipoxins; Lung; Myofibroblasts; Phosphorylation; Receptors, Formyl Peptide; Receptors, Lipoxin; RNA, Messenger; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2015 |
Activation of autophagy in macrophages by pro-resolving lipid mediators.
Topics: Animals; Apoptosis; Autophagy; Cytokines; Docosahexaenoic Acids; Half-Life; Inflammation; Lipoxins; Macrophages; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout | 2015 |
Inflammation activation and resolution in human tendon disease.
Topics: Adolescent; Adult; Arachidonate 15-Lipoxygenase; Aspirin; Female; Humans; Immunohistochemistry; In Vitro Techniques; Inflammation; Interferon-gamma; Interferons; Lectins, C-Type; Lipopolysaccharides; Lipoxins; Male; Mannose Receptor; Mannose-Binding Lectins; NF-kappa B; Receptors, Cell Surface; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; STAT6 Transcription Factor; Tendinopathy; Tendons; Young Adult | 2015 |
Understanding PGE2, LXA4 and LTB4 balance during Mycobacterium tuberculosis infection through mathematical model.
Topics: Apoptosis; Computer Simulation; Dinoprostone; Humans; Inflammation; Leukotriene B4; Lipoxins; Macrophages; Models, Theoretical; Mycobacterium Infections; Mycobacterium tuberculosis; Necrosis; Phenotype; Treatment Outcome; Virulence | 2016 |
In Vivo Availability of Pro-Resolving Lipid Mediators in Oxazolone Induced Dermal Inflammation in the Mouse.
Topics: Animals; Calibration; Chromatography, Liquid; Cyclooxygenase 2; Dermis; Hydroxyeicosatetraenoic Acids; Inflammation; Inflammation Mediators; Injections, Subcutaneous; Leukotriene B4; Lipids; Lipoxins; Luminescent Measurements; Mass Spectrometry; Mice, Inbred C57BL; Oxazolone; Peptidylprolyl Isomerase; Reproducibility of Results; Ribosomal Proteins | 2015 |
Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Blood-Brain Barrier; Blotting, Western; Brain Edema; Enzyme-Linked Immunosorbent Assay; Gene Knockdown Techniques; Inflammation; Injections, Intraventricular; Interleukin-1beta; Interleukin-6; Lipoxins; Male; Memory; Neuropsychological Tests; Neutrophil Infiltration; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Lipoxin; Signal Transduction; Spatial Learning; Subarachnoid Hemorrhage | 2016 |
Inflammatory bowel disease as a disorder of an imbalance between pro- and anti-inflammatory molecules and deficiency of resolution bioactive lipids.
Topics: Fatty Acids, Unsaturated; Humans; Inflammation; Inflammation Mediators; Inflammatory Bowel Diseases; Leukotrienes; Lipids; Lipoxins; Models, Biological; Receptors, G-Protein-Coupled | 2016 |
Lipoxin A4 attenuates LPS-induced mouse acute lung injury via Nrf2-mediated E-cadherin expression in airway epithelial cells.
Topics: Acute Lung Injury; Animals; Cadherins; Cell Line; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Lipopolysaccharides; Lipoxins; Lung; Mice; NF-E2-Related Factor 2 | 2016 |
Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection.
Topics: Animals; Axotomy; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Inflammation; Injections, Spinal; Lipoxins; Male; Mice; Microglia; Neuralgia; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Spinal Cord Injuries | 2016 |
ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland.
Topics: Animals; Apoptosis; Aquaporin 5; Cytokines; Docosahexaenoic Acids; Down-Regulation; Female; Inflammation; Leukocytes; Lipopolysaccharides; Lipoxins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Receptor, Muscarinic M3; Receptors, Formyl Peptide; Submandibular Gland; Tight Junctions; Up-Regulation; Xerostomia | 2016 |
Epigenetic regulation of the formyl peptide receptor 2 gene.
Topics: Acetylation; Cell Line; Cell Line, Tumor; Chromatin; E1A-Associated p300 Protein; Endothelial Cells; Epigenesis, Genetic; Epithelial Cells; Histones; Humans; Inflammation; Lipoxins; Methylation; Neutrophils; Organ Specificity; Primary Cell Culture; Receptors, Formyl Peptide; Receptors, Lipoxin; RNA, Messenger; Signal Transduction | 2016 |
Altering the Anti-inflammatory Lipoxin Microenvironment: a New Insight into Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis.
Topics: Adaptor Proteins, Signal Transducing; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cell Line; CRISPR-Cas Systems; Cyclooxygenase 2; Endothelial Cells; Gene Expression Regulation; Herpesvirus 8, Human; Host-Pathogen Interactions; Humans; Inflammation; Lipoxins; Lymphoma, Primary Effusion; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Proto-Oncogene Proteins c-akt; RNA, Viral; Sarcoma, Kaposi; Signal Transduction | 2016 |
Immobilization and delivery of biologically active Lipoxin A
Topics: Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Humans; Inflammation; Lipoxins; Periodontal Diseases; Periodontal Ligament; Polyesters; Polyethylene Glycols; Stem Cells | 2016 |
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.
Topics: 8,11,14-Eicosatrienoic Acid; Bacterial Proteins; Bronchoalveolar Lavage Fluid; Cell Line; Crystallography, X-Ray; Cystic Fibrosis; Humans; Inflammation; Lipoxins; Lung Diseases; Neutrophil Activation; Neutrophils; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Virulence Factors | 2017 |
Maresin 1 induces a novel pro-resolving phenotype in human platelets.
Topics: Adaptor Proteins, Signal Transducing; Blood Platelets; Cardiovascular Diseases; Docosahexaenoic Acids; Hemostasis; Humans; Inflammation; Lipoxins; Myocardial Infarction; Phenotype; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, G-Protein-Coupled | 2017 |
Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation.
Topics: Animals; Asthma; Disease Models, Animal; Eicosapentaenoic Acid; Inflammation; Inflammation Mediators; Interferon-gamma; Interleukin-23; Lipoxins; Lung; Mice | 2008 |
Signal pathway involved in inhibition by lipoxin A(4) of production of interleukins induced in endothelial cells by lipopolysaccharide.
Topics: Animals; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Inflammation; Interleukins; Lipopolysaccharides; Lipoxins; Male; Myeloid Differentiation Factor 88; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction | 2008 |
Prophylactic effects of omega-3 polyunsaturated fatty acids and luteolin on airway hyperresponsiveness and inflammation in cats with experimentally-induced asthma.
Topics: Animals; Ascaris suum; Asthma; Bronchoalveolar Lavage Fluid; Cat Diseases; Cats; Fatty Acids, Omega-3; Female; Inflammation; Lipoxins; Luteolin; Male | 2010 |
Lipoxin A4 generation is decreased in aspirin-sensitive patients in lysine-aspirin nasal challenge in vivo model.
Topics: Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Drug Tolerance; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Leukotriene C4; Lipoxins; Lysine; Middle Aged; Nasal Provocation Tests; Poaceae | 2009 |
The effect of Lipoxin A4 on the interaction between macrophage and osteoblast: possible role in the treatment of aseptic loosening.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty; Bone Cements; Cell Communication; Cell Line; Coculture Techniques; Cytokines; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Lipoxins; Macrophages; Mice; Organ Culture Techniques; Osteitis; Osteoblasts; Polymethyl Methacrylate; Prostheses and Implants; Prosthesis Failure; RNA Interference; Up-Regulation | 2009 |
Lipoxin a(4) attenuates microvascular fluid leak during inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Fluids; Capillary Permeability; Endothelium, Vascular; Female; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lipoxins; Microcirculation; Models, Animal; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Signal Transduction | 2009 |
Lipoxin A(4) reduces lipopolysaccharide-induced inflammation in macrophages and intestinal epithelial cells through inhibition of nuclear factor-kappaB activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cells, Cultured; Coculture Techniques; Cytokines; Epithelial Cells; Humans; Inflammation; Intestinal Mucosa; Lipopolysaccharides; Lipoxins; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Tumor Necrosis Factor-alpha | 2010 |
A synthetic analog of 15-epi-lipoxin A4 inhibits human monocyte apoptosis: involvement of ERK-2 and PI3-kinase.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Humans; Inflammation; Lipoxins; Mitochondria; Mitogen-Activated Protein Kinase 1; Monocytes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled | 2010 |
Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury.
Topics: Administration, Topical; Animals; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Autacoids; Cornea; Corneal Diseases; Down-Regulation; Gene Deletion; Inflammation; Lipoxins; Metabolic Networks and Pathways; Mice; Neovascularization, Pathologic; Phenotype | 2010 |
NF-kappaB is involved in inhibition of lipoxin A4 on dermal inflammation and hyperplasia induced by mezerein.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Cell Line; Cytokines; Dermis; Disease Models, Animal; Diterpenes; Female; Humans; Hyperplasia; Inflammation; Keratinocytes; Lipoxins; Mice; Mice, Inbred Strains; NF-kappa B | 2010 |
Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation.
Topics: Amino Acid Sequence; Animals; Annexin A1; Carrageenan; Chemotaxis; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Flow Cytometry; Immunoblotting; Inflammation; Leukocytes; Ligands; Lipoxins; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Peptides; Phosphorylation; Receptors, Formyl Peptide; Zymosan | 2010 |
Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4.
Topics: 8,11,14-Eicosatrienoic Acid; Acute Disease; Animals; Anticholesteremic Agents; Cell Line; Disease Models, Animal; Female; Humans; Hypercholesterolemia; Inflammation; Inflammation Mediators; Lipoxins; Lovastatin; Male; Mice; Neutrophils; Pneumonia; Respiratory Mucosa | 2010 |
Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Inflammation; Inflammation Mediators; Lipoxins; Male; Mice; Nitrobenzenes; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides | 2010 |
Depletion of regulatory T cells facilitates growth of established tumors: a mechanism involving the regulation of myeloid-derived suppressor cells by lipoxin A4.
Topics: Animals; Antibodies, Monoclonal; Cyclophosphamide; Inflammation; Lipoxins; Lipoxygenases; Liver Neoplasms; Lymphocyte Depletion; Mice; Mice, Inbred BALB C; Mice, Nude; Mutagens; Myeloid Cells; Neoplasms, Experimental; Receptors, Cell Surface; T-Lymphocytes, Regulatory | 2010 |
Lipoxin A(4), a potential anti-inflammatory drug targeting the skin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cytokines; Epidermis; Fibroblasts; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Interleukin-8; Keratinocytes; Lipoxins; Models, Biological; Psoriasis; Skin | 2011 |
Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature.
Topics: Animals; Annexin A1; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Membrane; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Inflammation; Inflammation Mediators; Lipoxins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvessels; Neutrophils; Oligopeptides; Peptide Fragments; Protein Transport; Receptors, Formyl Peptide; Receptors, Lipoxin; Time Factors | 2011 |
Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Chromatography, Liquid; Docosahexaenoic Acids; Humans; Inflammation; Keratinocytes; Lipids; Lipoxins; Male; Mice; Microspheres; Molecular Mimicry; Nanoparticles; Neutrophils; Peritonitis; Tandem Mass Spectrometry; Temporomandibular Joint; Temporomandibular Joint Disorders; Wound Healing | 2011 |
Lipoxin A4 inhibits the production of proinflammatory cytokines induced by β-amyloid in vitro and in vivo.
Topics: Active Transport, Cell Nucleus; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; Cell Nucleus; Cerebral Cortex; Cytokines; Hippocampus; I-kappa B Proteins; Inflammation; Interleukin-1beta; Lipoxins; Male; Mice; Mice, Inbred C57BL; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2011 |
What formyl peptide receptors, if any, are triggered by compound 43 and lipoxin A4?
Topics: Animals; Arrestins; beta-Arrestins; Calcium; Cell Line, Tumor; HL-60 Cells; Humans; Inflammation; Lipoxins; Mice; NADPH Oxidases; Neutrophils; Protein Transport; Pyrazoles; Reactive Oxygen Species; Receptors, Formyl Peptide; Receptors, Lipoxin; Signal Transduction | 2011 |
Lipoxins as biomarkers of lupus and other inflammatory conditions.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Cytokines; Fatty Acids; Humans; Inflammation; Kidney Glomerulus; Leukotrienes; Lipoxins; Lupus Erythematosus, Systemic; Models, Biological; Nephritis; Receptors, G-Protein-Coupled | 2011 |
Lipoxin a4 increases survival by decreasing systemic inflammation and bacterial load in sepsis.
Topics: Animals; Bacterial Load; Chemokine CCL2; Inflammation; Interleukin-10; Interleukin-6; Kaplan-Meier Estimate; Lipoxins; Male; NF-kappa B; Phagocytosis; Rats; Rats, Sprague-Dawley; Sepsis | 2011 |
Aspirin-triggered lipoxin A4 attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Enzyme Activation; Inflammation; Interleukin-1beta; Lipopolysaccharides; Lipoxins; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2011 |
Macrophage sub-populations and the lipoxin A4 receptor implicate active inflammation during equine tendon repair.
Topics: Animals; Antigens, Differentiation; Gene Expression Regulation; Horses; Image Processing, Computer-Assisted; Inflammation; Lectins, C-Type; Lipopolysaccharide Receptors; Lipoxins; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Microscopy, Fluorescence; Models, Biological; Phenotype; Receptors, Cell Surface; Receptors, Immunologic; Receptors, Lipoxin; Spleen; Tendon Injuries; Tendons | 2012 |
Lipoxin A4 attenuates adipose inflammation.
Topics: Adipose Tissue; Animals; Female; Glucose Transporter Type 4; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Interleukin-10; Interleukin-6; Lipoxins; Mice; Mice, Inbred C57BL; Obesity; Tumor Necrosis Factor-alpha | 2012 |
Ultrarush venom immunotherapy and the lipoxin a4 inflammation resolution pathway.
Topics: Adult; Animals; Arthropod Venoms; Bee Venoms; Desensitization, Immunologic; Female; Humans; Hymenoptera; Hypersensitivity, Immediate; Inflammation; Lipoxins; Male; Middle Aged | 2012 |
Effect of lipoxin A4 on myocardial ischemia reperfusion injury following cardiac arrest in a rabbit model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Female; Heart Arrest; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipoxins; Male; Myocardial Reperfusion Injury; NF-kappa B; Rabbits; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2013 |
Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor.
Topics: Allosteric Site; Amyloidogenic Proteins; Animals; Anti-Inflammatory Agents; Brain; Endocannabinoids; Inflammation; Kinetics; Lipoxins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neuroprotective Agents; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Spatial Behavior | 2012 |
Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease.
Topics: Aging; Animals; Dinoprost; Dinoprostone; Horses; Inflammation; Lipoxins; Receptors, Formyl Peptide; Receptors, Lipoxin; Tendinopathy; Tendon Injuries; Tendons | 2012 |
Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions.
Topics: Cell Movement; Chemotaxis, Leukocyte; Docosahexaenoic Acids; Equipment Design; Humans; Inflammation; Leukocytes; Lipoxins; Microfluidic Analytical Techniques; Monocytes; Nanotechnology; Neutrophils; Pancreatic Elastase | 2012 |
Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome.
Topics: Animals; Anti-Inflammatory Agents; CD3 Complex; Cell Polarity; Choline; Cognition Disorders; Disease Models, Animal; Hippocampus; Inflammation; Leukotriene B4; Lipoxins; Lymphocyte Count; Macrophages; Male; Metabolic Syndrome; Physical Conditioning, Animal; Postoperative Period; Rats; Receptors, Adrenergic, beta-2; Signal Transduction; Spleen; T-Lymphocytes, Regulatory | 2013 |
An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Cell Movement; Chemotaxis, Leukocyte; Croton Oil; Disease Models, Animal; Diterpenes; Female; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Hypersensitivity, Delayed; Iloprost; Inflammation; Leukotriene B4; Lipoxins; Mice; Phthalic Anhydrides; Skin; Terpenes | 2002 |
Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense.
Topics: 3T3 Cells; Animals; Cell Line; Chromatography, Liquid; Dinoprostone; Female; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene B4; Lipoxins; Male; Mass Spectrometry; Mice; Mice, Transgenic; Neutrophil Infiltration; NF-kappa B; Peritoneum; Peritonitis; Plasmids; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Skin; Transfection; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Lipoxins and aspirin-triggered lipoxins in airway responses.
Topics: Animals; Aspirin; Bronchi; Bronchial Hyperreactivity; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukocytes; Lipoxins; Male; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin | 2003 |
15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Endothelium; Inflammation; Interleukin-1; Leukocytes; Lipoxins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peritonitis; Rats; Rats, Wistar | 2004 |
Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ear, External; Inflammation; Injections, Intravenous; Lipoxins; Lung Diseases; Male; Mice; Peritonitis; Reperfusion Injury; Zymosan | 2004 |
An oily, sustained counter-regulatory response to TB.
Topics: Animals; Humans; Inflammation; Lipoxins; Mice; Mycobacterium tuberculosis; Tuberculosis | 2005 |
Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basic Helix-Loop-Helix Transcription Factors; Brain; Cells, Cultured; Dendritic Cells; Inflammation; Interleukin-12; Lipoxins; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; RNA, Messenger; Spleen; Suppressor of Cytokine Signaling Proteins; Toxoplasma | 2006 |
Lipoxin biosynthesis in inflammatory bowel disease.
Topics: Animals; Arachidonate 15-Lipoxygenase; Colitis, Ulcerative; Colon; Enzyme Inhibitors; Fluorenes; Humans; Inflammation; Intestinal Mucosa; Lipoxins; Lipoxygenase Inhibitors; Mice | 2006 |
Not all eicosanoids are bad.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Inflammation Mediators; Lipoxins; Parasitic Diseases | 2006 |
Glucocorticoids co-interact with lipoxin A4 via lipoxin A4 receptor (ALX) up-regulation.
Topics: Adult; CD11b Antigen; DNA Primers; Glucocorticoids; Humans; Inflammation; Lipoxins; Neutrophils; Receptors, Formyl Peptide; Receptors, Lipoxin; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2007 |
Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing.
Topics: Animals; Aspirin; Astrocytes; Blotting, Western; Carrageenan; Hyperalgesia; Immunohistochemistry; Inflammation; Inflammation Mediators; Lipoxins; Male; Pain; Rats; Rats, Sprague-Dawley; Receptors, Lipoxin; Spinal Cord | 2007 |
Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Ascitic Fluid; Benzothiazoles; Dogs; Ear; Edema; Eicosanoids; Enzyme Inhibitors; Epoxide Hydrolases; Female; Humans; Hydroxyurea; Inflammation; Leukotriene B4; Leukotriene C4; Lipoxins; Lipoxygenase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neutrophil Infiltration; Peritonitis; Piperidines; Recombinant Proteins | 2007 |
The required role of endogenously produced lipoxin A4 and annexin-1 for the production of IL-10 and inflammatory hyporesponsiveness in mice.
Topics: Animals; Annexin A1; Germ-Free Life; Inflammation; Interleukin-10; Intestines; Lipoxins; Mice; Mice, Mutant Strains; Peptides; Reperfusion Injury | 2007 |
Identification and characterization of a high-affinity leukotriene B4 receptor on guinea pig T lymphocytes and its regulation by lipoxin A4.
Topics: Animals; Carbazoles; Female; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Indole Alkaloids; Inflammation; Leukotriene B4; Lipoxins; Protein Kinase C; Receptors, Leukotriene B4; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Transcellular pathways and cell adhesion as potential contributors to leukotriene and lipoxin biosynthesis in acute glomerulonephritis.
Topics: Animals; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Glomerular Mesangium; Glomerulonephritis; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Kidney Glomerulus; Leukotriene C4; Lipoxins; Neutrophils; Phagocytes | 1997 |
Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor 1alpha-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemokine CXCL2; Chemokines; Cytokines; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Interleukin-1; Interleukin-4; Leukocytes; Lipoxins; Male; Mice; Molecular Structure; Monokines; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Recombinant Proteins; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
Local and systemic delivery of an aspirin-triggered lipoxin stable analog inhibits neutrophil trafficking.
Topics: Animals; Aspirin; Cell Movement; Drug Carriers; Hydroxyeicosatetraenoic Acids; Inflammation; Lipoxins; Mice; Neutrophils; Tumor Necrosis Factor-alpha | 2000 |
Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation.
Topics: 15-Oxoprostaglandin 13-Reductase; Alcohol Oxidoreductases; Animals; Anions; Chromatography, High Pressure Liquid; Chromatography, Liquid; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Horses; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Lipoxins; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Models, Chemical; Neutrophils; Oxidoreductases; Recombinant Proteins; Superoxides; Swine; Time Factors | 2000 |
Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses.
Topics: Animals; Aspirin; Binding, Competitive; Capillary Permeability; Cell Line; COS Cells; Dose-Response Relationship, Drug; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene D4; Lipoxins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Leukotriene; Receptors, Leukotriene B4; Receptors, Lipoxin; Recombinant Proteins; RNA; Stereoisomerism; Tritium | 2001 |
Lipoxins inhibit microvascular inflammatory actions of leukotriene B4.
Topics: Animals; Cheek; Chemotaxis, Leukocyte; Cricetinae; Hydroxyeicosatetraenoic Acids; Inflammation; Leukocytes; Leukotriene B4; Lipoxins; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Muscle, Smooth, Vascular | 1991 |
Lipoxin A4 inhibits leukotriene B4-induced inflammation in the hamster cheek pouch.
Topics: Animals; Capillary Permeability; Cheek; Cricetinae; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene B4; Lipoxins; Male; Mesocricetus; Microcirculation | 1989 |