fosmidomycin has been researched along with Typhus, Epidemic Louse-Borne in 1 studies
fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source
fosmidomycin : Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.
Typhus, Epidemic Louse-Borne: The classic form of typhus, caused by RICKETTSIA PROWAZEKII, which is transmitted from man to man by the louse Pediculus humanus corporis. This disease is characterized by the sudden onset of intense headache, malaise, and generalized myalgia followed by the formation of a macular skin eruption and vascular and neurologic disturbances.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antibiotic fosmidomycin will know as inhibitor of the nonmevalonate pathway of isoprenoid biosynthesis and as possible antimalarial drug, was shown to possess a certain protective effect on mice experimentally infected with tularemia, tiphus or coli-septicemia." | 3.72 | [Effect of fosfidomycin on development of various infections in mice]. ( Bakhteeva, IV; Biketov, SF; Biniukov, VI; Borzenkov, VN; Ostrovskiĭ, DN; Potapov, VD; Titareva, GM; Wiesner, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Potapov, VD | 1 |
| Bakhteeva, IV | 1 |
| Borzenkov, VN | 1 |
| Titareva, GM | 1 |
| Wiesner, J | 1 |
| Biniukov, VI | 1 |
| Ostrovskiĭ, DN | 1 |
| Biketov, SF | 1 |
1 other study available for fosmidomycin and Typhus, Epidemic Louse-Borne
| Article | Year |
|---|---|
[Effect of fosfidomycin on development of various infections in mice].
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Escherichia coli Infections; Fosfomycin; Mice; | 2003 |