Arachnoid Cysts

Intracranial or spinal cavities containing a cerebrospinal-like fluid, the wall of which is composed of arachnoidal cells. They are most often developmental or related to trauma. Intracranial arachnoid cysts usually occur adjacent to arachnoidal cistern and may present with HYDROCEPHALUS; HEADACHE; SEIZURES; and focal neurologic signs. (From Joynt, Clinical Neurology, 1994, Ch44, pp105-115)

Synonym
Intracranial Arachnoid Cysts
Arachnoid Cysts
Leptomeningeal Cysts
Arachnoid Cysts, Intracranial
Arachnoid Diverticula

Excerpt	Reference
"Symptomatic arachnoid cysts are amenable to simple surgical drainage."	( Atlas, MD; Chang, P; Fagan, PA; Roche, J, 1998)
"Intracranial arachnoid cysts are cerebrospinal fluid-filled collections between arachnoid layers."	( Choong, CT; Lee, SH, 1998)
"Arachnoid cysts are reported to account for about 1% of all intracranial space-occupying lesions."	( Kabil, MS; Shahinian, HK, 2007)
"Spinal arachnoid cysts are relatively uncommon an intramedullary location is believed to be extremely rare."	( Ergün, R; Gezici, AR, 2008)
"Spinal arachnoid cysts are rare lesions in the pediatric population."	( Bond, AE; Bowen, I; Krieger, MD; McComb, JG; Zada, G, 2012)
"Intracranial arachnoid cysts are rare but the widespread use of brain imaging has disclosed many asymptomatic cysts."	( Amin, OS; Shwani, SS, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1 (0.79)	23.3326
1990's	42 (33.33)	12.5806
2000's	51 (40.48)	18.1394
2010's	30 (23.81)	28.8240
2020's	2 (1.59)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	5	0
carnitine	low	2	0
choline	low	2	0
salicylic acid	low	3	0
creatine	low	1	0
formaldehyde	low	1	0
glutaric acid	low	4	0
glycine	low	1	0
inositol	low	1	0
phenol	low	1	0
phenytoin	low	1	0
acetaminophen	low	1	0
acetazolamide	low	4	0
albendazole	low	2	0
amitriptyline	low	1	0
carbamazepine	low	1	0
carprofen	low	1	0
clonazepam	low	1	0
diazepam	low	1	0
pentetic acid	low	5	0
valproic acid	low	1	0
fluconazole	low	1	0
flumazenil	low	1	0
gabapentin	low	3	0
isoflurane	low	1	0
2-propanol	low	2	0
lorazepam	low	1	0
maprotiline	low	1	0
meperidine	low	1	0
apnea	low	1	0
pamidronate	low	1	0
phenobarbital	low	1	0
piracetam	low	1	0
propofol	low	1	0
risperidone	low	1	0
sevoflurane	low	1	0
succinylcholine	low	1	0
temozolomide	low	1	0
thiotepa	low	1	0
prednisolone	low	3	0
prednisone	low	1	0
pilocarpine	low	1	0
alanine	low	1	0
aspartic acid	low	2	0
carbostyril	low	1	0
levodopa	low	1	0
cytarabine	low	1	0
methylprednisolone	low	1	0
cyproterone acetate	low	1	0
dimenhydrinate	low	1	0
glycopyrrolate	low	1	0
neodymium	low	1	0
titanium	low	2	0
gadolinium	medium	12	1
yttrium	low	1	0
phenyl acetate	low	1	0
sufentanil	low	1	0
propiconazole	low	12	0
topotecan	low	1	0
aripiprazole	low	1	0
remifentanil	low	2	0
n-acetylaspartic acid	low	2	0
iopamidol	low	1	0
cephalosporin c	low	1	0
fluorodeoxyglucose f18	low	5	0
ketorolac tromethamine	low	1	0
fibrinogen	low	1	0
deoxyglucose	low	1	0
methotrexate	medium	2	1
technetium tc 99m pentetate	low	1	0
fibrin	low	1	0
bromochloroacetic acid	low	2	0
thiopental	low	1	0
phenylephrine hydrochloride	low	2	0
hydromorphone	low	1	0
levetiracetam	low	1	0
naloxone	low	1	0
oxycodone	low	1	0
pregabalin	low	1	0
cefotaxime	low	1	0
gadolinium dtpa	medium	4	1
ro 16-0154	low	1	0
technetium tc 99m exametazime	low	4	0
piperidines	low	2	0
interleukin-8	low	1	0
acenocoumarol	low	1	0
technetium tc 99m medronate	low	1	0
nusinersen	low	1	0
clozapine	low	1	0
dacarbazine	low	1	0
ganciclovir	low	1	0
phosphorus radioisotopes	low	2	0

Protein Targets (965)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
RAR-related orphan receptor gamma	27	0	0	27
GLI family zinc finger 3	22	0	0	22
AR protein	33	0	0	33
aldehyde dehydrogenase 1 family, member A1	17	0	0	17
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
retinoid X nuclear receptor alpha	19	0	0	19
estrogen nuclear receptor alpha	39	0	0	39
peroxisome proliferator-activated receptor delta	11	0	0	11
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
activating transcription factor 6	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
Histone H2A.x	9	0	0	9
thyroid hormone receptor beta isoform a	9	0	0	9
heat shock protein beta-1	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 1	22	0	0	22
lamin isoform A-delta10	28	0	0	28
Voltage-dependent calcium channel gamma-2 subunit	13	0	0	13
Glutamate receptor 2	13	0	0	13
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	10	0	0	10
Luciferase	8	0	0	8
G	13	0	0	13
peroxisome proliferator activated receptor gamma	18	0	0	18
euchromatic histone-lysine N-methyltransferase 2	26	0	0	26
thyroid stimulating hormone receptor	11	0	0	11
chromobox protein homolog 1	16	0	0	16
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
geminin	31	0	0	31
muscleblind-like protein 1 isoform 1	8	0	0	8
Interferon beta	16	0	0	16
HLA class I histocompatibility antigen, B alpha chain	13	0	0	13
Guanine nucleotide-binding protein G	3	0	0	3
Inositol hexakisphosphate kinase 1	13	0	0	13
cytochrome P450 2C9, partial	13	0	0	13
ATAD5 protein, partial	11	0	0	11
GLS protein	9	0	0	9
Microtubule-associated protein tau	8	0	0	8
Smad3	5	0	0	5
thyroid stimulating hormone receptor	13	0	0	13
nuclear receptor subfamily 1, group I, member 3	22	0	0	22
progesterone receptor	18	0	0	18
EWS/FLI fusion protein	17	0	0	17
estrogen-related nuclear receptor alpha	26	0	0	26
aryl hydrocarbon receptor	9	0	0	9
thyroid hormone receptor beta isoform 2	23	0	0	23
peripheral myelin protein 22	16	0	0	16
cytochrome P450 3A4 isoform 1	11	0	0	11
Gamma-aminobutyric acid receptor subunit pi	11	12	2	25
ATP-binding cassette sub-family C member 3	0	32	0	32
Multidrug resistance-associated protein 4	0	32	0	33
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	8	1	13
UDP-glucuronosyltransferase 1A9	0	0	0	3
Bile salt export pump	0	10	0	10
Bile salt export pump	0	39	0	39
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	11	1	20
Carbonic anhydrase 2	0	11	2	20
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	1	1	3
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 3	0	7	1	11
Cytochrome P450 3A4	0	10	0	11
Cytochrome P450 2D6	0	7	1	9
Cytochrome P450 2C9	0	10	0	11
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	11	12	2	25
Sulfotransferase 1A1	0	0	0	2
Gamma-aminobutyric acid receptor subunit delta	11	12	2	25
Gamma-aminobutyric acid receptor subunit gamma-2	11	12	3	26
UDP-glucuronosyltransferase 1-6	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	11	12	2	25
Gamma-aminobutyric acid receptor subunit alpha-3	11	12	2	25
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	7	1	11
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	8	1	12
Gamma-aminobutyric acid receptor subunit gamma-1	11	12	2	25
Gamma-aminobutyric acid receptor subunit alpha-2	11	12	2	25
Gamma-aminobutyric acid receptor subunit alpha-4	11	12	2	25
Gamma-aminobutyric acid receptor subunit gamma-3	11	12	2	25
Gamma-aminobutyric acid receptor subunit alpha-6	11	12	2	25
Carbonic anhydrase 5A, mitochondrial	0	7	1	12
Prostaglandin G/H synthase 2	0	4	0	5
Carbonic anhydrase 7	0	7	1	11
Nuclear receptor ROR-gamma	6	0	0	6
Cytochrome P450 2J2	0	7	0	8
Gamma-aminobutyric acid receptor subunit alpha-1	11	12	3	26
Gamma-aminobutyric acid receptor subunit beta-3	11	12	2	25
Gamma-aminobutyric acid receptor subunit beta-2	11	12	3	26
Carbonic anhydrase 9	0	8	1	13
GABA theta subunit	11	12	2	25
Canalicular multispecific organic anion transporter 1	0	31	0	31
Carbonic anhydrase 15	0	4	0	6
Carbonic anhydrase 13	0	6	0	9
Gamma-aminobutyric acid receptor subunit epsilon	11	12	2	25
Carbonic anhydrase 14	0	7	1	12
Carbonic anhydrase 5B, mitochondrial	0	7	1	12
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	8	0	0	8
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
thioredoxin reductase	22	0	0	22
GALC protein	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	17	0	0	17
glucocorticoid receptor [Homo sapiens]	23	0	0	23
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	13	0	0	13
Carbonic anhydrase	0	1	0	1
Bloom syndrome protein isoform 1	17	0	0	17
survival motor neuron protein isoform d	13	0	0	13
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	9	0	10
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	3	1	4
5-hydroxytryptamine receptor 2A	0	9	0	9
Androgen receptor	0	6	0	6
Translocator protein	0	2	1	4
Cannabinoid receptor 1	0	2	0	2
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	5	0	6
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	0	0	1
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	3	0	4
5-hydroxytryptamine receptor 2B	0	7	1	8
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	4	1	6
Cytochrome P450 2C19	0	1	0	2
Delta-type opioid receptor	0	6	2	8
Mu-type opioid receptor	0	8	2	10
Carbonic anhydrase	0	1	0	2
Kappa-type opioid receptor	0	4	1	6
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	4	1	0	5
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	1	0	2
D(2) dopamine receptor	0	8	0	9
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	4	1	5
Fatty-acid amide hydrolase 1	0	5	0	5
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	5	1	7
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	4	0	4
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase 3	0	3	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	5	1	6
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	2
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	4	1	6
Carbonic anhydrase 4	0	2	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	5	1	7
Proton-coupled amino acid transporter 1	0	4	0	4
Adenosine deaminase	0	0	0	1
glp-1 receptor, partial	6	0	0	6
Fumarate hydratase	7	0	0	7
TDP1 protein	24	0	0	24
caspase 7, apoptosis-related cysteine protease	5	0	0	5
farnesoid X nuclear receptor	12	0	0	12
pregnane X nuclear receptor	19	0	0	19
polyprotein	7	0	0	7
67.9K protein	8	0	0	8
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
caspase-3	5	0	0	5
IDH1	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
cellular tumor antigen p53 isoform a	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
transcriptional regulator ERG isoform 3	8	0	0	8
histone deacetylase 9 isoform 3	4	0	0	4
mitogen-activated protein kinase 1	5	0	0	5
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
Vif	0	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
neuropeptide S receptor isoform A	5	0	0	5
Cellular tumor antigen p53	26	0	0	26
Integrin beta-3	3	0	0	3
Integrin alpha-IIb	3	0	0	3
Methionine aminopeptidase	0	1	0	1
Inositol monophosphatase 1	7	0	0	7
ATPase family AAA domain-containing protein 5	10	0	0	10
Ataxin-2	14	0	0	14
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
USP1 protein, partial	13	0	0	13
NFKB1 protein, partial	4	0	0	4
cytochrome P450 2D6	14	0	0	14
cytochrome P450 2D6 isoform 1	6	0	0	6
D(1A) dopamine receptor	9	0	0	9
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
muscarinic acetylcholine receptor M1	12	0	0	12
Solute carrier family 22 member 1	0	6	0	9
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
5-hydroxytryptamine receptor 4	0	14	0	14
Albumin	0	0	6	6
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	13	0	13
Muscarinic acetylcholine receptor M2	0	14	2	16
Muscarinic acetylcholine receptor M4	0	12	1	13
Muscarinic acetylcholine receptor M1	0	7	0	8
Muscarinic acetylcholine receptor M3	0	7	0	8
Muscarinic acetylcholine receptor M4	0	7	0	8
Muscarinic acetylcholine receptor M5	0	7	0	8
Muscarinic acetylcholine receptor M5	0	13	0	13
Alpha-2A adrenergic receptor	0	12	0	12
Muscarinic acetylcholine receptor M2	0	7	0	8
Muscarinic acetylcholine receptor M1	0	13	3	16
Angiotensin-converting enzyme	0	8	0	8
D(2) dopamine receptor	0	12	1	17
Alpha-2B adrenergic receptor	0	12	0	12
Alpha-2C adrenergic receptor	0	11	0	11
5-hydroxytryptamine receptor 1A	0	13	1	14
Muscarinic acetylcholine receptor M3	0	15	1	16
D(1A) dopamine receptor	0	11	0	13
D(1B) dopamine receptor	0	5	0	7
UDP-glucuronosyltransferase 1A4	0	0	0	3
Sodium-dependent noradrenaline transporter	0	14	0	14
Histamine H2 receptor	0	10	0	10
Alpha-1D adrenergic receptor	0	13	0	13
5-hydroxytryptamine receptor 2A	0	14	0	16
5-hydroxytryptamine receptor 2C	0	16	1	17
5-hydroxytryptamine receptor 1B	0	8	0	8
5-hydroxytryptamine receptor 1D	0	3	0	3
5-hydroxytryptamine receptor 1F	0	3	0	3
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	3	0	3
Sodium-dependent serotonin transporter	0	10	0	10
5-hydroxytryptamine receptor 7	0	5	0	5
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Histamine H1 receptor	0	14	2	18
D(3) dopamine receptor	0	11	1	15
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	4	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	15	1	16
Alpha-1A adrenergic receptor	0	7	1	8
Histamine H2 receptor	8	1	0	10
5-hydroxytryptamine receptor 6	0	10	0	11
5-hydroxytryptamine receptor 7	0	2	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Sodium-dependent dopamine transporter	0	9	0	9
Potassium voltage-gated channel subfamily H member 2	0	15	0	15
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium channel protein type 9 subunit alpha	0	5	0	5
5-hydroxytryptamine receptor 4	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	8	0	8
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	11	0	11
5-hydroxytryptamine receptor 3B	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	6	0	6
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
5-hydroxytryptamine receptor 3E	0	2	0	2
acetylcholinesterase	9	0	0	9
SMAD family member 2	6	0	0	6
PPM1D protein	3	0	0	3
SMAD family member 3	6	0	0	6
estrogen receptor 2 (ER beta)	13	0	0	13
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
lysosomal alpha-glucosidase preproprotein	2	0	0	2
mu-type opioid receptor isoform MOR-1	0	0	2	2
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
nuclear receptor ROR-gamma isoform 1	9	0	0	9
histone acetyltransferase KAT2A isoform 1	9	0	0	9
5-hydroxytryptamine receptor 2A	0	0	2	2
Solute carrier family 22 member 2	0	3	0	4
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 3B	0	2	0	2
ATP-dependent translocase ABCB1	0	4	0	8
5-hydroxytryptamine receptor 1A	0	5	3	8
Neuronal acetylcholine receptor subunit alpha-4	2	4	0	6
Neuronal acetylcholine receptor subunit beta-2	2	4	0	6
Alpha-1B adrenergic receptor	0	6	1	7
D	0	6	0	6
D(4) dopamine receptor	0	6	0	9
Alpha-1D adrenergic receptor	0	6	1	7
D(4) dopamine receptor	0	5	0	5
Histamine H1 receptor	0	4	1	5
5-hydroxytryptamine receptor 7	0	4	0	4
Alpha-1A adrenergic receptor	0	5	0	5
Alpha-1B adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 3A	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Spike glycoprotein	19	1	1	21
5-hydroxytryptamine receptor 3D	0	2	0	2
Multidrug and toxin extrusion protein 2	0	3	0	3
5-hydroxytryptamine receptor 3C	0	2	0	2
Multidrug and toxin extrusion protein 1	0	4	0	4
Chain A, Ferritin light chain	6	0	0	6
phosphopantetheinyl transferase	7	0	0	7
cytochrome P450 2C19 precursor	7	0	0	7
lethal factor (plasmid)	4	0	0	4
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	6
Glutamate receptor ionotropic, NMDA 2C	0	4	1	6
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	4	1	6
Glutamate receptor ionotropic, NMDA 3B	0	4	1	6
Glutamate receptor ionotropic, NMDA 3A	0	4	1	6
Vpr	2	0	0	2
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, serum paraoxonase	0	1	0	1
DNA polymerase kappa isoform 1	6	0	0	6
Neutrophil cytosol factor 1	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
nonstructural protein 1	4	0	0	4
vitamin D3 receptor isoform VDRA	8	0	0	8
Complement C5	0	0	1	1
TAR DNA-binding protein 43	7	0	0	7
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Albumin	0	2	3	6
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 1	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 6	0	3	0	6
Solute carrier family 22 member 7	0	1	0	2
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	2	0	3
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 8	0	1	0	1
Beta-lactamase VIM-1	0	0	0	1
Solute carrier family 22 member 7	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
Thrombopoietin	2	0	0	2
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	1
Adenylate cyclase type 1	0	3	0	3
Caspase-7	1	0	0	1
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
caspase-3	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
M-phase phosphoprotein 8	7	0	0	7
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	2	0	2
Procathepsin L	0	1	1	2
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Replicase polyprotein 1ab	0	1	1	2
Sphingomyelin phosphodiesterase	0	1	0	1
D(3) dopamine receptor	0	6	0	6
Alpha-2B adrenergic receptor	0	5	1	6
D(2) dopamine receptor	0	3	0	3
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
Adenylate cyclase type 3	0	3	0	3
Alpha-2C adrenergic receptor	0	5	1	6
Alpha-2A adrenergic receptor	0	5	1	6
Sodium-dependent dopamine transporter	0	6	0	6
D(1B) dopamine receptor	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Mu-type opioid receptor	0	9	5	15
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	6	2	9
Kappa-type opioid receptor	0	6	4	11
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	1	2
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
D	0	3	0	3
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	1	1	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Solute carrier family 22 member 1	0	1	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
ATP-dependent phosphofructokinase	10	0	0	10
Gamma-aminobutyric acid receptor subunit pi	0	7	0	7
Gamma-aminobutyric acid receptor subunit delta	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	0	7
Gamma-aminobutyric acid receptor subunit beta-1	0	5	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	8	6	14
Gamma-aminobutyric acid receptor subunit beta-1	0	7	2	9
Gamma-aminobutyric acid receptor subunit gamma-2	0	8	5	13
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	0	7
Gamma-aminobutyric acid receptor subunit beta-3	0	8	4	12
Translocator protein	0	2	0	2
Translocator protein	0	3	0	3
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	7	5	12
Gamma-aminobutyric acid receptor subunit alpha-3	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit beta-2	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	2	9
Gamma-aminobutyric acid receptor subunit epsilon	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	2	9
Gamma-aminobutyric acid receptor subunit gamma-1	0	7	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	0	7	0	7
Gamma-aminobutyric acid receptor subunit theta	0	7	0	7
Beta-1 adrenergic receptor	0	1	0	1
glucocerebrosidase	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
peripheral myelin protein 22 isoform 1	4	0	0	4
cytochrome P450 2C9 precursor	3	0	0	3
DNA polymerase beta	2	0	0	2
DNA polymerase iota isoform a (long)	10	0	0	10
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Endothelin receptor type B	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Histamine H4 receptor	0	1	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Transporter	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Chain A, Cruzipain	1	0	0	1
pregnane X receptor	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
Glucocorticoid receptor	0	8	2	15
Progesterone receptor	0	3	0	4
Glycine receptor subunit alpha-1	0	8	0	8
Androgen receptor	0	4	0	4
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Adenosine receptor A2b	0	1	0	1
ORF73	0	0	1	1
endonuclease IV	5	0	0	5
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
interleukin 8	1	0	0	1
Matrix metalloproteinase-9	0	1	0	1
Isocitrate lyase	0	1	0	1
Gamma-aminobutyric acid	0	2	1	3
Fatty acid-binding protein, liver	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	2	0	0	2
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	4	0	4
Rap guanine nucleotide exchange factor 3	1	0	0	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	4	0	4
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Histone deacetylase 1	0	4	0	4
Lanosterol 14-alpha demethylase	0	1	1	2
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	4	0	4
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
regulator of G-protein signaling 4	7	0	0	7
flap endonuclease 1	6	0	0	6
thyrotropin-releasing hormone receptor	1	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	3
thioredoxin glutathione reductase	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Thymidine kinase	0	1	0	1
ClpP	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
Chain A, Protein (aspartate Aminotransferase)	0	0	1	1
Chain A, Aspartate Aminotransferase	0	0	1	1
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Solute carrier family 22 member 7	0	0	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Glycine receptor subunit alpha-1	0	0	2	2
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Solute carrier family 22 member 3	0	0	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Amyloid-beta precursor protein	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Parkin	1	0	0	1
huntingtin isoform 2	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Synaptic vesicle glycoprotein 2A	0	2	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	3	0	0	3
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
glucokinase regulatory protein	1	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
Polyphenol oxidase 2	0	1	0	4
Plasma kallikrein	0	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosinase	0	1	0	1
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
phosphoglycerate kinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	4
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
Thymidylate synthase	0	1	0	1
alpha-galactosidase	2	0	0	2
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	1	2
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Kappa-type opioid receptor	0	4	2	6
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Adenosine receptor A1	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Acetylcholinesterase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Chain A, Ferritin light chain	0	0	2	2
Endolysin	0	0	1	1
beta-2 adrenergic receptor	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Acetylcholinesterase	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
Tyrosine-protein kinase ABL2	0	1	0	1
hemoglobin subunit beta	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
NPYLR7B	0	0	1	1
tyrosine-protein kinase Yes	1	0	0	1
DNA topoisomerase 1	0	1	2	4
DNA topoisomerase 2-alpha	0	1	0	1
DNA topoisomerase 2-beta	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	1	2
Endothelial PAS domain-containing protein 1	0	0	1	1
Cocaine esterase	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Research

Studies (126)

Protein Targets (965)

Arachnoid Cysts

Synonyms(5)

Research Excerpts

Overview

Research

Studies (126)

Drugs Studied (106)

Protein Targets (965)