bromochloroacetic-acid and Arachnoid-Cysts

To describe a histologically well-documented adult case of a giant supratentorial enterogenous cyst (EC). Fewer than 15 cases of supratentorial ECs are on record: 8 associated with the brain hemispheres or the overlying meninges, 4 with the sellar region, and 2 with the optic nerve.. A 31-year-old woman complained of long-standing mild left brachial and crural motor deficit precipitated by headache and signs of intracranial hypertension. Magnetic resonance imaging revealed a huge cyst overlying the frontoparietal brain.. Symptoms were relieved by evacuation of the cyst content by means of a Rickam's reservoir, and the lesion was subsequently removed in toto. Histological and immunohistochemical examination of the cyst wall clearly established the enterogenous nature of its epithelium. Follow-up for up to 2 years after intervention showed no sign of recurrence, and symptoms, including treatment-resistant seizures in the postoperative period, have entirely subsided.. Supratentorial ECs, distinctly rare in adult patients, may in some cases present as giant lesions. Total removal seems to be curative once careful examination has eliminated the possibility of a metastasis from an unknown primary. A correct histological diagnosis is important because, in contrast to other benign cysts of similar location and size, ECs may be prone to intraoperative dissemination.

Topics: Adult; Arachnoid Cysts; Biomarkers, Tumor; Carcinoembryonic Antigen; Central Nervous System Cysts; Craniotomy; Diagnosis, Differential; Epithelium; Female; Follow-Up Studies; Frontal Lobe; Humans; Intracranial Hypertension; Keratins; Magnetic Resonance Imaging; Meningeal Neoplasms; Mucin-1; Neural Tube Defects; Parietal Lobe; Supratentorial Neoplasms

A case of epithelial cyst in the cerebellopontine angle is reported. The cyst wall showed glandular epithelium with areas of non-keratinized stratified epithelium and flattened cuboidal cells. The glandular areas stained positively with antibodies to cytokeratin. In addition, the cyst wall contained areas of arachnoid tissue. This, and the unusual position of the cyst, suggest that the epithelial elements in the cyst wall may be metaplastic in origin. Similar previously described cysts were considered to be endodermal in origin.

Topics: Adult; Arachnoid; Arachnoid Cysts; Cerebellar Diseases; Cerebellopontine Angle; Female; Humans; Keratins; Magnetic Resonance Imaging; Tomography, X-Ray Computed