Alexia

A cognitive disorder characterized by an impaired ability to comprehend written and printed words or phrases despite intact vision. This condition may be developmental or acquired. Developmental dyslexia is marked by reading achievement that falls substantially below that expected given the individual's chronological age, measured intelligence, and age-appropriate education. The disturbance in reading significantly interferes with academic achievement or with activities of daily living that require reading skills. (From DSM-IV)

Synonym
Dyslexia, Developmental
Word Blindness
Reading Disability, Developmental
Dyslexia
Reading Disorder
Alexia
Reading Disorder, Developmental
Developmental Reading Disorder

Excerpt	Reference
"Dyslexia is conceptualized as resulting from an ego deficit in language processing; this deficit is seen as contributing to the ADHD-type symptoms often seen in dyslexic children."	( Migden, S, 1998)
"Dyslexia is a language disorder in which reading ability is compromised because of poor phonologic skills."	( Abbott, RD; Berninger, VW; Corina, D; Dager, SR; Echelard, DR; Maravilla, KR; Marro, K; Richards, TL; Serafini, S; Steury, K, 2000)
"Neglect dyslexia is a reading disorder which affects the identification of portions of words or sentences and is typically due to right-brain damage."	( Savazzi, S, 2003)
"Developmental dyslexia is a specific disorder of reading acquisition characterized by a phonological core deficit."	( Brandeis, D; Brem, S; Bucher, K; Martin, E; Maurer, U; Schulz, E; van der Mark, S, 2008)
"Although dyslexia is widely diagnosed and affects a very important portion of the childhood population, a conceptual definition of the condition is still lacking."	( Artigas-Pallarés, J, 2009)
"Developmental dyslexia is a highly prevalent and specific disorder of reading acquisition characterised by impaired reading fluency and comprehension."	( Brandeis, D; Brem, S; Bucher, K; Martin, E; Maurer, U; Schulz, E; van der Mark, S, 2009)
"Dyslexia is a condition characterized by difficulty of reading given adequate intelligence and educational opportunities, primarily associated with a phonological processing deficit."	( Beneventi, H; Ersland, L; Hugdahl, K; Tønnessen, FE, 2010)
"Dyslexia is one of the common problems seen in children worldwide."	( Mehta, M; Pattanayak, RD; Sagar, R; Sharma, P, 2018)
"Dyslexia is a neurodevelopmental disorder that manifests as a reading disability despite normal intelligence and adequate educational opportunity."	( Devasenapathy, S; Mehta, A; Midha, R; Naskar, T; Prajapati, B; Sagar, R; Singh, NC; Sinha, S; Ummekulsum, M, 2018)
"Dyslexia is a neurobiological impairment that primarily affects reading ability."	( Dzalani, H; Mahadir, A; Norhayati, I; Normah, CD; Nurul Anis, MY; Rogayah, AR, 2018)
"Dyslexia is a common neurodevelopmental disorder caused by a significant genetic component."	( Dholakia, K; Ewart, JY; Gasparoli, F; Gostic, M; Martinelli, A; Paracchini, S; Sillar, KT; Tello, JA; Tucker, C; Yang, Z, 2019)
"Dyslexia is a common learning disorder that renders children susceptible to poor health outcomes and many elements of socioeconomic difficulty."	( Gaab, N; Ness, M; Petscher, Y; Rappaport, L; Sanfilippo, J; Zuckerman, B, 2020)

Excerpt	Reference
"Children with dyslexia have difficulty learning to recognize written words owing to subtle deficits in oral language related to processing sounds and accessing words automatically."	( Abbott, RD; Berninger, VW; Corina, D; Craft, S; Dager, SR; Hayes, CE; Heide, AC; Posse, S; Richards, TL; Serafini, S; Shaw, D; Steury, K; Strauss, W, 1999)
"As dyslexia has a partial genetic basis, the PAF hypothesis predicts that dyslexia may be negatively associated with a family history of cancer."	( Taylor, KE, 2004)

Excerpt	Reference
"Children without dyslexia (n=10) received nonphonological treatment, and those with dyslexia received phonological (n=11) or nonphonological (n=9) treatment."	( Berninger, V; Maravilla, K; Muse, A; Richards, T; Stock, P; Wagner, R; Winn, W, 2007)
"The atomoxetine-treated dyslexia-only subjects significantly improved from baseline to week 32 on ADHDRS-IV-Parent:Inv Inattentive subscale, K-SCT Parent and Teacher subscales, and WMTB-C Phonological Loop and Central Executive component scores."	( Dunn, D; Hooper, SR; McBurnett, K; Shaywitz, B; Shaywitz, S; Wietecha, L; Wigal, SB; Williams, D, 2013)
"Atomoxetine-treated dyslexia-only patients compared with placebo patients had significantly greater improvement (p < 0."	( Hooper, SR; Kronenberger, WG; McBurnett, K; Shaywitz, B; Shaywitz, S; Wietecha, L; Wigal, S; Williams, D, 2017)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	98 (37.12)	23.3326
1990's	21 (7.95)	12.5806
2000's	59 (22.35)	18.1394
2010's	70 (26.52)	28.8240
2020's	16 (6.06)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	3	0
choline	low	5	0
creatine	low	2	0
lactic acid	medium	2	1
iodine	low	3	0
melatonin	low	1	0
niacin	low	1	0
uric acid	low	1	0
2-amino-5-phosphonovalerate	low	1	0
phenytoin	low	1	0
amantadine	low	1	0
caffeine	low	1	0
chlordiazepoxide	low	1	0
amphetamine	low	2	0
diazepam	medium	2	1
fluphenazine	low	1	0
flumazenil	low	1	0
guanfacine	medium	1	1
haloperidol	low	1	0
lidocaine	low	1	0
imipramine	low	3	0
iofetamine	low	1	0
meclizine	medium	2	1
methylphenidate	medium	26	9
nitrazepam	medium	2	2
pemoline	low	2	0
phenobarbital	low	1	0
piracetam	medium	18	15
prilocaine	low	1	0
thioridazine	low	1	0
dextroamphetamine	low	2	0
idoxuridine	low	1	0
aspartic acid	low	5	0
glutamine	low	1	0
tyrosine	low	1	0
phenylalanine	low	2	0
histidine	low	1	0
ethylene oxide	low	1	0
propylene oxide	low	1	0
cyclizine	low	1	0
methylprednisolone	low	1	0
penicillin v	low	1	0
dimenhydrinate	low	1	0
methoxyhydroxyphenylglycol	low	1	0
acetylcysteine	low	2	0
hydroxyethyl methacrylate	low	1	0
s,n,n'-tripropylthiocarbamate	low	7	0
pimozide	low	1	0
manganese	low	1	0
cadmium	low	2	0
cetylpyridinium chloride anhydrous	medium	3	1
4-methoxyamphetamine	low	1	0
glutamic acid	low	2	0
propiconazole	low	2	0
fomesafen	medium	5	1
fenoxycarb	low	5	0
atomoxetine hydrochloride	medium	5	5
n-acetylaspartic acid	low	5	0
xenon radioisotopes	low	1	0
fluorodeoxyglucose f18	low	2	0
nicotine	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	2	0
deoxyglucose	low	1	0
carnosine	medium	1	1
oxytocin	medium	1	1
inositol 3-phosphate	low	1	0
arachidonic acid	low	1	0
cocaine	low	1	0
eicosapentaenoic acid	medium	1	1
isomethyleugenol	low	1	0
digoxin	medium	2	1
nitrogen dioxide	low	1	0
bilirubin	low	1	0
gamma-linolenic acid	low	1	0
lead	low	5	0
cysteine	low	1	0
phosphorus	low	1	0
selenium	low	1	0
dolichols	medium	1	1
ro 25-6981	low	1	0
psd 502	low	1	0
sb 204990	low	1	0
lactulose	low	1	0
indocyanine green	low	1	0
enerbol	low	1	0
jaw	low	1	0
nad	low	1	0
ubiquinone	medium	1	1
ro13-9904	low	1	0
sodium ethylxanthate	low	3	0
piperidines	low	1	0
exudates	low	3	0
acyclovir	low	1	0
eye	low	20	0
ego	low	4	0
technetium tc 99m bicisate	low	1	0

Protein Targets (891)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	13	0	0	13
Chain A, Cruzipain	4	0	0	4
regulator of G-protein signaling 4	16	0	0	16
Platelet-activating factor receptor	0	2	0	2
Inositol monophosphatase 1	8	0	0	8
euchromatic histone-lysine N-methyltransferase 2	28	0	0	28
Bloom syndrome protein isoform 1	12	0	0	12
peripheral myelin protein 22 isoform 1	6	0	0	6
D(1A) dopamine receptor	12	0	0	12
lamin isoform A-delta10	16	0	0	16
Glutamate receptor 1	0	3	1	4
Glutamate receptor ionotropic, NMDA 1	0	10	1	14
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	10	1	14
Glutamate receptor ionotropic, NMDA 2B	0	10	1	14
Glutamate receptor ionotropic, NMDA 2C	0	10	1	14
Glutamate receptor ionotropic, NMDA 2D	0	10	1	14
Glutamate receptor ionotropic, NMDA 3B	0	10	1	14
Glutamate receptor ionotropic, NMDA 3A	0	10	1	14
ATP-dependent phosphofructokinase	16	0	0	16
5-hydroxytryptamine receptor 2C	0	9	3	12
5-hydroxytryptamine receptor 2A	0	9	3	12
5-hydroxytryptamine receptor 1A	0	16	4	20
5-hydroxytryptamine receptor 1B	0	9	3	12
5-hydroxytryptamine receptor 1D	0	5	3	8
5-hydroxytryptamine receptor 1F	0	5	3	8
5-hydroxytryptamine receptor 2B	0	9	3	12
5-hydroxytryptamine receptor 6	0	2	3	5
Sodium-dependent serotonin transporter	0	14	2	16
Sodium-dependent serotonin transporter	0	6	1	8
5-hydroxytryptamine receptor 7	0	4	3	7
5-hydroxytryptamine receptor 5A	0	2	3	5
5-hydroxytryptamine receptor 5B	0	2	3	5
5-hydroxytryptamine receptor 3A	0	2	3	5
5-hydroxytryptamine receptor 4	0	2	3	5
5-hydroxytryptamine receptor 3B	0	2	3	5
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
acetylcholinesterase	9	0	0	9
dopamine D1 receptor	1	0	0	1
15-lipoxygenase, partial	5	0	0	5
pregnane X receptor	4	0	0	4
phosphopantetheinyl transferase	13	0	0	13
RAR-related orphan receptor gamma	19	0	0	19
USP1 protein, partial	12	0	0	12
NFKB1 protein, partial	5	0	0	5
Microtubule-associated protein tau	11	0	0	11
Thrombopoietin	4	0	0	4
AR protein	29	0	0	29
glucocorticoid receptor [Homo sapiens]	14	0	0	14
retinoic acid nuclear receptor alpha variant 1	21	0	0	21
retinoid X nuclear receptor alpha	12	0	0	12
farnesoid X nuclear receptor	10	0	0	10
estrogen nuclear receptor alpha	27	0	0	27
vitamin D (1,25- dihydroxyvitamin D3) receptor	12	0	0	12
arylsulfatase A	16	0	0	16
thyroid hormone receptor beta isoform a	9	0	0	9
thyroid hormone receptor beta isoform 2	20	0	0	20
heat shock protein beta-1	7	0	0	7
flap endonuclease 1	7	0	0	7
geminin	23	0	0	23
peripheral myelin protein 22	12	0	0	12
survival motor neuron protein isoform d	4	0	0	4
muscarinic acetylcholine receptor M1	12	0	0	12
Histone deacetylase 3	0	2	0	2
Solute carrier family 22 member 6	0	1	0	2
Histone deacetylase 4	0	2	0	2
Guanine nucleotide-binding protein G	3	0	0	3
Histone deacetylase 1	0	2	0	2
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Ataxin-2	13	0	0	13
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
Chain A, Ferritin light chain	6	0	0	6
Thymidine kinase	0	2	0	2
thioredoxin reductase	15	0	0	15
GLS protein	12	0	0	12
TDP1 protein	24	0	0	24
Smad3	3	0	0	3
thyroid stimulating hormone receptor	7	0	0	7
EWS/FLI fusion protein	7	0	0	7
activating transcription factor 6	6	0	0	6
Histone H2A.x	5	0	0	5
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Solute carrier family 22 member 1	0	4	0	8
ATP-binding cassette sub-family C member 3	0	17	0	17
Multidrug resistance-associated protein 4	0	17	0	17
Bile salt export pump	0	2	0	2
Bile salt export pump	0	23	0	23
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	5	1	6
Cytochrome P450 2J2	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	0	0	2
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Canalicular multispecific organic anion transporter 1	0	16	0	16
Thymidine kinase	0	1	0	1
GLI family zinc finger 3	20	0	0	20
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
putative alpha-glucosidase	1	0	0	1
histone acetyltransferase KAT2A isoform 1	9	0	0	9
Solute carrier family 22 member 2	0	3	0	5
Glutamate receptor ionotropic, NMDA 2D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	4	0	4
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Spike glycoprotein	7	1	1	9
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	4	0	4
Solute carrier family 22 member 1	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	4	0	4
Multidrug and toxin extrusion protein 1	0	5	0	5
Solute carrier family 22 member 2	0	4	0	5
Solute carrier family 22 member 3	0	1	0	1
Phenylethanolamine N-methyltransferase	0	3	0	3
Cytochrome P450 2A6	0	3	1	4
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	2	0	2
Sodium-dependent dopamine transporter	0	8	1	9
Sigma non-opioid intracellular receptor 1	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	5	1	6
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
Chain A, Beta-lactamase	7	0	0	7
thioredoxin glutathione reductase	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	13	0	0	13
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
cellular tumor antigen p53 isoform a	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
vitamin D3 receptor isoform VDRA	7	0	0	7
nuclear receptor ROR-gamma isoform 1	13	0	0	13
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
DNA polymerase kappa isoform 1	7	0	0	7
cytochrome P450 3A4 isoform 1	8	0	0	8
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	8	10	1	19
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	0	0	7
Prostaglandin G/H synthase 1	0	1	0	2
Trypsin	0	3	0	3
Coagulation factor VII	0	3	0	3
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Aromatase	0	3	0	3
Tissue factor	0	3	0	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	8	10	1	19
Gamma-aminobutyric acid receptor subunit delta	8	10	1	19
Gamma-aminobutyric acid receptor subunit gamma-2	8	10	2	20
Gamma-aminobutyric acid receptor subunit alpha-5	8	10	1	19
Gamma-aminobutyric acid receptor subunit alpha-3	8	10	1	19
Gamma-aminobutyric acid receptor subunit gamma-1	8	10	1	19
Gamma-aminobutyric acid receptor subunit alpha-2	8	10	1	19
Gamma-aminobutyric acid receptor subunit alpha-4	8	10	1	19
Gamma-aminobutyric acid receptor subunit gamma-3	8	10	1	19
Gamma-aminobutyric acid receptor subunit alpha-6	8	10	1	19
Prostaglandin G/H synthase 2	0	0	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Histamine H2 receptor	10	1	0	12
10 kDa heat shock protein, mitochondrial	0	1	0	1
Calmodulin	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	8	10	2	20
Gamma-aminobutyric acid receptor subunit beta-3	8	10	1	19
Gamma-aminobutyric acid receptor subunit beta-2	8	10	2	20
Prostaglandin G/H synthase 2	0	1	0	2
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
GABA theta subunit	8	10	1	19
Gamma-aminobutyric acid receptor subunit epsilon	8	10	1	19
Solute carrier organic anion transporter family member 1B3	0	5	0	6
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	5	0	6
cytochrome P450 2C19 precursor	5	0	0	5
lethal factor (plasmid)	8	0	0	8
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	1	0	9
Carbonic anhydrase 2	0	1	0	9
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	3
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	6
Carbonic anhydrase 4	0	0	0	3
glp-1 receptor, partial	9	0	0	9
estrogen receptor 2 (ER beta)	11	0	0	11
nuclear receptor subfamily 1, group I, member 3	18	0	0	18
progesterone receptor	17	0	0	17
cytochrome P450 family 3 subfamily A polypeptide 4	8	0	0	8
estrogen-related nuclear receptor alpha	24	0	0	24
cytochrome P450 2D6	8	0	0	8
peroxisome proliferator-activated receptor delta	9	0	0	9
IDH1	7	0	0	7
thyroid stimulating hormone receptor	9	0	0	9
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
nuclear factor erythroid 2-related factor 2 isoform 1	18	0	0	18
Cellular tumor antigen p53	15	0	0	15
Sodium-dependent noradrenaline transporter	0	17	1	18
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Caspase-7	1	0	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
pregnane X nuclear receptor	17	0	0	17
chromobox protein homolog 1	13	0	0	13
DNA polymerase beta	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Potassium channel subfamily K member 2	0	4	3	7
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Adenosine receptor A3	0	3	0	3
Replicase polyprotein 1ab	0	5	1	6
Glutamate receptor 2	10	2	1	13
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	3	0	3
Adenosine receptor A1	0	3	0	7
Amine oxidase [flavin-containing] B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	2	1	4
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	1	1	4
Adenosine receptor A2a	0	2	0	7
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Guanine deaminase	0	2	0	2
cytochrome P450 2D6 isoform 1	9	0	0	9
cytochrome P450 2C9 precursor	4	0	0	4
Carbonic anhydrase 4	0	0	0	4
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
SMAD family member 2	4	0	0	4
SMAD family member 3	4	0	0	4
caspase 7, apoptosis-related cysteine protease	6	0	0	6
67.9K protein	6	0	0	6
peroxisome proliferator activated receptor gamma	14	0	0	14
caspase-3	6	0	0	6
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
thyrotropin-releasing hormone receptor	2	0	0	2
mitogen-activated protein kinase 1	5	0	0	5
Caspase-2	0	0	1	1
ATPase family AAA domain-containing protein 5	9	0	0	9
potassium voltage-gated channel subfamily H member 2 isoform d	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	0	8	4	12
Translocator protein	0	4	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	8	3	11
Gamma-aminobutyric acid receptor subunit alpha-4	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	8	3	11
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	8	4	12
Gamma-aminobutyric acid receptor subunit alpha-3	0	8	3	11
Histamine H1 receptor	0	14	0	14
Gamma-aminobutyric acid receptor subunit alpha-2	0	8	2	10
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-4	1	5	2	9
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-2	1	5	2	9
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	5	2	8
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	7	0	7
Gamma-aminobutyric acid receptor subunit delta	0	7	0	7
Amyloid-beta precursor protein	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	5	0	5
Tryptophan 5-hydroxylase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	7	1	8
D	0	6	0	6
Alpha-2B adrenergic receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	5	0	5
Alpha-2A adrenergic receptor	0	5	0	5
Liver carboxylesterase 1	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	7	2	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	1	8
D(2) dopamine receptor	0	8	0	8
Gamma-aminobutyric acid receptor subunit epsilon	0	7	0	7
Sodium-dependent dopamine transporter	0	17	1	18
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	15	0	15
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	1	8
Sodium-dependent dopamine transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	7	0	7
Sigma non-opioid intracellular receptor 1	0	10	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	0	7	0	7
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	7	0	7
Transporter	0	5	1	7
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
5-hydroxytryptamine receptor 4	0	12	0	12
Muscarinic acetylcholine receptor M2	0	9	0	9
Muscarinic acetylcholine receptor M4	0	9	0	9
Muscarinic acetylcholine receptor M5	0	8	0	8
Alpha-2A adrenergic receptor	0	12	0	12
Cytochrome P450 2D6	0	5	0	5
Muscarinic acetylcholine receptor M1	0	10	0	10
Muscarinic acetylcholine receptor M3	0	9	0	9
Alpha-1D adrenergic receptor	0	11	0	11
5-hydroxytryptamine receptor 2A	0	14	0	14
5-hydroxytryptamine receptor 2C	0	13	0	13
D(3) dopamine receptor	0	8	1	11
5-hydroxytryptamine receptor 2B	0	12	0	12
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Gamma-aminobutyric acid	0	2	1	3
G	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
Interferon beta	9	0	0	9
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
Fatty acid-binding protein, liver	0	1	0	1
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	1	1	3
Albumin	0	0	3	3
ATP-dependent translocase ABCB1	0	6	0	9
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Translocator protein	0	1	0	1
Translocator protein	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Inositol hexakisphosphate kinase 1	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
cytochrome P450 2C9, partial	6	0	0	6
interleukin 8	3	0	0	3
PAX8	0	0	0	1
ATAD5 protein, partial	8	0	0	8
PPM1D protein	3	0	0	3
STAT3, partial	0	1	0	1
alpha-galactosidase	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
tumor necrosis factor	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	5	0	0	5
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
ras-related protein Rab-9A	5	0	0	5
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Integrin beta-3	4	0	1	5
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Integrin alpha-IIb	4	0	1	5
Cytochrome P450 3A4	0	6	0	8
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Nuclear receptor ROR-gamma	4	1	1	6
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Aldo-keto reductase family 1 member B1	0	8	0	8
Alpha-2B adrenergic receptor	0	10	0	10
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Cytochrome P450 1A2	0	4	0	5
Retinoic acid receptor RXR-alpha	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Oxoeicosanoid receptor 1	0	1	0	1
Luciferase	6	0	0	6
endonuclease IV	3	0	0	3
muscleblind-like protein 1 isoform 1	2	0	0	2
TAR DNA-binding protein 43	7	0	0	7
Fumarate hydratase	5	0	0	5
NADPH oxidase 1	0	1	0	1
polyprotein	5	0	0	5
glucocerebrosidase	2	0	0	2
Snq2p	0	0	0	3
Caspase-7	4	0	0	4
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
caspase-3	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
M-phase phosphoprotein 8	5	0	0	5
Transmembrane protease serine 2	0	1	1	2
Epidermal growth factor receptor	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Tyrosine-protein kinase Fyn	0	2	0	2
Procathepsin L	0	1	1	2
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Angiotensin-converting enzyme	0	5	0	5
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	9	2	13
Androgen receptor	0	3	0	3
Alpha-1B adrenergic receptor	0	7	0	7
Alpha-2C adrenergic receptor	0	8	0	8
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	6	0	7
D(4) dopamine receptor	0	6	1	9
D(1B) dopamine receptor	0	3	0	4
Histamine H2 receptor	0	6	0	6
Trypanothione reductase	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
Mu-type opioid receptor	0	5	1	6
Delta-type opioid receptor	0	3	0	3
Kappa-type opioid receptor	0	5	0	5
Alpha-1A adrenergic receptor	0	8	0	8
D(1A) dopamine receptor	4	1	0	5
5-hydroxytryptamine receptor 6	0	7	0	7
5-hydroxytryptamine receptor 7	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Angiotensin-converting enzyme 2	0	1	1	2
Histamine H3 receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	3
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
transcriptional regulator ERG isoform 3	3	0	0	3
neuropeptide S receptor isoform A	2	0	0	2
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
WRN	1	0	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
DNA polymerase eta isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	6	0	0	6
Free fatty acid receptor 1	0	0	1	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
POU domain, class 2, transcription factor 1	0	0	0	1
Nischarin	0	1	0	1
nonstructural protein 1	3	0	0	3
Adenylate cyclase type 1	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
UDP-glucuronosyltransferase 1A9	0	1	0	2
Major prion protein	0	0	2	2
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	4	0	4
Muscarinic acetylcholine receptor M4	0	5	0	5
5-hydroxytryptamine receptor 1A	0	3	0	3
Muscarinic acetylcholine receptor M5	0	5	0	5
Beta-2 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M2	0	4	0	4
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	3
Beta-1 adrenergic receptor	0	1	0	1
D(3) dopamine receptor	0	5	0	5
D(2) dopamine receptor	0	2	0	2
Adenylate cyclase type 3	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	3
Alpha-1D adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 3A	0	1	0	1
D(1B) dopamine receptor	0	5	0	5
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
D(4) dopamine receptor	0	5	0	5
Histamine H1 receptor	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	3	0	3
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Kappa-type opioid receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 4 subunit alpha	0	5	0	6
Adenylate cyclase type 8	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	3	0	3
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	6	0	6
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	5	0	5
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Adenylyl cyclase 7	0	1	0	1
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	5	0	5
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	6	0	6
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	3	0	3
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Carbonic anhydrase 12	0	0	0	3
Plasma kallikrein	0	0	0	3
Carbonic anhydrase 3	0	0	0	3
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase 6	0	0	0	3
Carbonic anhydrase 5A, mitochondrial	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase 7	0	0	0	3
Carbonic anhydrase	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	3	0	4
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 15	0	0	0	3
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 14	0	0	0	3
Carbonic anhydrase 5B, mitochondrial	0	0	0	3
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
Vpr	1	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidine kinase	0	0	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sphingomyelin phosphodiesterase	0	1	0	1
Cytochrome P450 2C19	0	1	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
D(2) dopamine receptor	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Envelope glycoprotein	0	0	1	1
Sodium-dependent serotonin transporter	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
aryl hydrocarbon receptor	4	0	0	4
histone deacetylase 9 isoform 3	1	0	0	1
Chymotrypsinogen A	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
ClpP	1	0	0	1
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Cytochrome P450 1B1	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucocorticoid receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Polyphenol oxidase 2	0	1	0	2
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Delta-type opioid receptor	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Mu-type opioid receptor	0	1	0	1
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Lysine-specific demethylase 4C	0	2	0	2
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	2	1	3
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
GALC protein	2	0	0	2
apical membrane antigen 1, AMA1	1	0	0	1
DNA polymerase III, partial	1	0	0	1
XBP1	0	1	0	1
huntingtin isoform 2	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
WD repeat-containing protein 48	0	1	0	1
Histamine H4 receptor	0	1	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Prolyl endopeptidase	0	1	0	1
Parkin	1	0	0	1
Proteasome subunit alpha type-6	0	0	1	1
Cathepsin D	0	1	0	1
Aldehyde oxidase	0	0	0	2
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(8)

Research Excerpts

Overview

Context

Treatment

Research

Studies (264)

Protein Targets (891)

Alexia

Synonyms(8)

Research Excerpts

Overview

Context

Treatment

Research

Studies (264)

Drugs Studied (116)

Protein Targets (891)