methylphenidate has been researched along with Alexia in 26 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These cases were selected from a prior quantitative study in which three antihistamines (meclizine, cyclizine, dimenhydrinate) and three stimulants (pemoline, methylphenidate, dextroamphetamine) were tested in variable combinations (using a specific clinical method) for favorable responses by 100 children characterized by diagnostic evidence of learning disabilities and cerebellar-vestibular dysfunctioning." | 3.68 | Dramatic favorable responses of children with learning disabilities or dyslexia and attention deficit disorder to antimotion sickness medications: four case reports. ( Levinson, HN, 1991) |
| "Methylphenidate led to an increase in activation in this region but had no effect on task performance." | 2.71 | The effects of methylphenidate on neural systems of attention in attention deficit hyperactivity disorder. ( Gore, JC; Marchione, KE; Shafritz, KM; Shaywitz, BA; Shaywitz, SE, 2004) |
| "Sixty-six children received individual reading instruction for 18 weeks, in combination with methylphenidate (mean daily dose 44." | 2.65 | Children with reading disorders--II. Effects of methylphenidate in combination with reading remediation. ( Feingold, I; Gittelman, R; Klein, DF, 1983) |
| " Mean dosage levels, individually titrated by the team psychiatrist, were highest for the reading-disabled group, lowest for those with suspected attention disorders." | 2.65 | Effects of methylphenidate on selective and sustained attention in hyperactive, reading-disabled, and presumably attention-disordered boys. ( Ackerman, PT; Dykman, RA; McCray, DS, 1980) |
| "Although dyslexia is widely diagnosed and affects a very important portion of the childhood population, a conceptual definition of the condition is still lacking." | 1.35 | [Dyslexia: a disease, a disorder or something else?]. ( Artigas-Pallarés, J, 2009) |
| " The augmenters were blindly titrated at significantly lower dosage levels than the reducers." | 1.27 | Auditory ERP augmentation-reduction and methylphenidate dosage needs in attention and reading disordered children. ( Ackerman, PT; Dykman, RA; Holcomb, PJ; McCray, DS, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (65.38) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artigas-Pallarés, J | 1 |
| Stiefelhagen, P | 1 |
| Shafritz, KM | 1 |
| Marchione, KE | 1 |
| Gore, JC | 1 |
| Shaywitz, SE | 1 |
| Shaywitz, BA | 1 |
| Keulers, EH | 1 |
| Hendriksen, JG | 1 |
| Feron, FJ | 1 |
| Wassenberg, R | 1 |
| Wuisman-Frerker, MG | 1 |
| Jolles, J | 1 |
| Vles, JS | 1 |
| Bental, B | 1 |
| Tirosh, E | 1 |
| Dykman, RA | 3 |
| Holcomb, PJ | 1 |
| Ackerman, PT | 3 |
| McCray, DS | 2 |
| Richardson, E | 4 |
| Gittelman, R | 3 |
| Klein, DF | 1 |
| Feingold, I | 1 |
| Aman, MG | 1 |
| Werry, JS | 1 |
| Tannock, R | 1 |
| Martinussen, R | 1 |
| Frijters, J | 1 |
| Hurst, DL | 1 |
| Bellak, L | 1 |
| Logue, GD | 1 |
| Levinson, HN | 1 |
| Kupietz, SS | 3 |
| Winsberg, BG | 3 |
| Fagan, JE | 1 |
| Kaplan, BJ | 1 |
| Raymond, JE | 1 |
| Edgington, ES | 1 |
| Maitinsky, S | 2 |
| Mendell, N | 2 |
| Kinsbourne, M | 1 |
| Spring, C | 1 |
| Greenberg, L | 1 |
| Scott, J | 1 |
| Hopwood, J | 1 |
| Peters, JE | 1 |
| Nichamin, SJ | 1 |
9 trials available for methylphenidate and Alexia
| Article | Year |
|---|---|
The effects of methylphenidate on neural systems of attention in attention deficit hyperactivity disorder.
Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Basal Ganglia; Central Nervous | 2004 |
Methylphenidate improves reading performance in children with attention deficit hyperactivity disorder and comorbid dyslexia: an unblinded clinical trial.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 2007 |
The effects of methylphenidate on word decoding accuracy in boys with attention-deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Cross-Over | 2008 |
Children with reading disorders--II. Effects of methylphenidate in combination with reading remediation.
Topics: Achievement; Attention; Child; Dyslexia; Female; Follow-Up Studies; Humans; Male; Mathematics; Methy | 1983 |
Methylphenidate and diazepam in severe reading retardation.
Topics: Child; Clinical Trials as Topic; Diazepam; Drug Therapy, Combination; Dyslexia; Humans; Methylphenid | 1982 |
Effects of methylphenidate on selective and sustained attention in hyperactive, reading-disabled, and presumably attention-disordered boys.
Topics: Attention; Attention Deficit Disorder with Hyperactivity; Child; Double-Blind Method; Dyslexia; Facu | 1980 |
Naming speed performance and stimulant effects indicate effortful, semantic processing deficits in attention-deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Central Nervous System Stimulan | 2000 |
Attention deficit disorder and specific reading disability: separate but often overlapping disorders.
Topics: Arousal; Attention; Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relationship | 1991 |
The failure of antimotion sickness medication to improve reading in developmental dyslexia: results of a randomized trial.
Topics: Child; Double-Blind Method; Dyslexia; Eye Movements; Female; Humans; Male; Meclizine; Methylphenidat | 1988 |
17 other studies available for methylphenidate and Alexia
| Article | Year |
|---|---|
[Dyslexia: a disease, a disorder or something else?].
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dyslexia; G | 2009 |
[Hyperkinetic syndrome and dyslexia. Medical help for the hyperactive child].
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dyslexia; H | 2002 |
Auditory ERP augmentation-reduction and methylphenidate dosage needs in attention and reading disordered children.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Double-Blind Method; Dyslexia; Evoked Potentia | 1983 |
The impact of phonemic processing instruction on the reading achievement of reading-disabled children.
Topics: Achievement; Attention Deficit Disorder with Hyperactivity; Child; Dyslexia; Female; Humans; Male; M | 1984 |
Indications for the use of stimulant treatment in learning disorders.
Topics: Child; Double-Blind Method; Dyslexia; Female; Humans; Male; Methylphenidate | 1980 |
Effect of methylphenidate on academic progress.
Topics: Attention Deficit Disorder with Hyperactivity; Dyslexia; Handwriting; Humans; Methylphenidate | 1978 |
A possible subgroup of the schizophrenic syndrome and implications for treatment.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dys | 1976 |
Dyslexia.
Topics: Attention; Child; Dextroamphetamine; Dyslexia; Humans; Hyperkinesis; Mental Processes; Mental Recall | 1975 |
Dramatic favorable responses of children with learning disabilities or dyslexia and attention deficit disorder to antimotion sickness medications: four case reports.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Cyclizine; | 1991 |
Stimulants and school performance.
Topics: Achievement; Attention Deficit Disorder with Hyperactivity; Child; Dyslexia; Humans; Methylphenidate | 1991 |
Effects of methylphenidate dosage in hyperactive reading-disabled children: I. Behavior and cognitive performance effects.
Topics: Adolescent; Child; Cognition; Dose-Response Relationship, Drug; Dyslexia; Humans; Hyperkinesis; Meth | 1988 |
Effects of methylphenidate dosage in hyperactive reading-disabled children: II. Reading achievement.
Topics: Achievement; Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relatio | 1988 |
Controlled trials of remedial approaches to reading disability.
Topics: Attention; Child; Dyslexia; Humans; Methylphenidate; Perception; Reading; Reinforcement, Social | 1985 |
School problems: diagnosis and treatment.
Topics: Agnosia; Amphetamine; Anxiety; Child; Child, Preschool; Cognition Disorders; Developmental Disabilit | 1973 |
Reaction time and effect of Ritalin on children with learning problems.
Topics: Attention; Child; Discrimination, Psychological; Dyslexia; Female; Form Perception; Humans; Hyperkin | 1973 |
Minimal brain dysfunctions in children.
Topics: Amphetamine; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Comm | 1974 |
Reading disorders in children.
Topics: Child; Child Development; Dyslexia; Humans; Methylphenidate | 1969 |