Page last updated: 2024-10-17

lactic acid and Furcation Defects

lactic acid has been researched along with Furcation Defects in 28 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Furcation Defects: Conditions in which a bifurcation or trifurcation of the molar tooth root becomes denuded as a result of periodontal disease. It may be followed by tooth mobility, temperature sensitivity, pain, and alveolar bone resorption.

Research Excerpts

ExcerptRelevanceReference
"To evaluate, clinically, the use of guided tissue regeneration (GTR) with a resorbable polylactic acid membrane (Atrisorb) in the treatment of Class II furcation defects in humans."9.11Guided tissue regeneration in Class II furcation defects using a resorbable polylactic acid barrier. ( Bremm, LL; Casati, MZ; Nociti, FH; Sallum, AW; Sallum, EA, 2004)
"This study evaluated two bioresorbable polylactic acid barriers (Epi-Guide and Guidor) to determine if design differences were of therapeutic significance in the treatment of Grade II furcation defects in humans."9.08Use of biodegradable polylactic acid barrier materials in the treatment of grade II periodontal furcation defects in humans--Part I: A multicenter investigative clinical study. ( Brekke, J; Derhalli, M; Nechamkin, SJ; Rapley, J; Ringeisen, TA; Vernino, AR; Wang, HL, 1998)
" This study was to compare long-term effectiveness of two different types of polylactic acid (PLA) membranes on periodontal regeneration in surgically created class II furcation defects in dogs."7.72Evaluation of periodontal healing in class II furcation defects following guided tissue regeneration with two different types of polylactic acid membranes. ( Cetiner, D; Gültekin, E; Kurtiş, B; Parlar, A; Unsal, B, 2004)
"To evaluate, clinically, the use of guided tissue regeneration (GTR) with a resorbable polylactic acid membrane (Atrisorb) in the treatment of Class II furcation defects in humans."5.11Guided tissue regeneration in Class II furcation defects using a resorbable polylactic acid barrier. ( Bremm, LL; Casati, MZ; Nociti, FH; Sallum, AW; Sallum, EA, 2004)
"This study evaluated guided tissue regeneration in Class II furcation defects after use of a polylactic acid biodegradable barrier in nine patients with mandibular molar defects."5.08Initial study of guided tissue regeneration in Class II furcation defects after use of a biodegradable barrier. ( Billen, JR; Dunn, RL; Laster, LL; Polson, AM; Polson, AP; Southard, GL, 1995)
"THE EFFICACY OF A BIOABSORBABLE polylactic acid based barrier was evaluated using naturally occurring buccal Class II furcation defects in beagle dogs."3.69Periodontal regeneration in naturally occurring Class II furcation defects in beagle dogs after guided tissue regeneration with bioabsorbable barriers. ( Bogle, G; Dunn, RL; Fulfs, JC; Garrett, S; Polson, AM; Rodgers, PW; Southard, GL; Stoller, NH; Swanbom, DD; Whitman, S, 1997)
"In 10 patients with treated chronic periodontitis, we randomly selected the 1st molars in the mandible with buccal degree II furcation involvement for either polylactic-citric-acid-ester (PLA) or glycolide-lactic-copolymer (PGL) GTR membrane therapy."2.70PMN responses following use of 2 biodegradable GTR membranes. ( Buchmann, R; Hasilik, A; Heinecke, A; Lange, DE, 2001)
" Therefore, to stimulate not only the soft tissues, but also the hard tissues, in this study EMD is combined with an injectable calcium phosphate cement (CaP; bone graft material)."1.39Regeneration of the periodontium using enamel matrix derivative in combination with an injectable bone cement. ( Bronckers, AL; Jansen, JA; Meijer, GJ; Oortgiesen, DA; Walboomers, XF, 2013)
"Class III furcation defects were created in the premolars of six adult cats."1.33Formation and resolution of ankylosis under application of recombinant human bone morphogenetic protein-2 (rhBMP-2) to class III furcation defects in cats. ( Kato, H; Kawanami, M; Morita, M; Odajima, T; Takahashi, D, 2005)
" The technique combined tetracycline treatment of a root planed root, grafting of the osseous defect with a demineralized freeze-dried bone allograft combined with tetracycline and the placement of a bioabsorbable matrix membrane, made of polylactic acid softened with citric acid ester."1.30A clinical evaluation of guided tissue regeneration with a bioabsorbable matrix membrane combined with an allograft bone graft. A series of case reports. ( Harris, RJ, 1997)
"During a healing period of 6 weeks, gingival recession resulting in device exposure occurred at 3 test and 10 control sites."1.29The influence of the design of two different bioresorbable barriers on the results of guided tissue regeneration therapy. An intra-individual comparative study in the monkey. ( Gottlow, J; Laurell, L; Lundgren, D; Mathisen, T; Nyman, S; Rask, M; Rylander, H, 1995)
"Measurements of gingival recession were recorded from color photographic slides taken weekly for 6 weeks following barrier placement."1.29Evaluation of the potential of a polylactic acid barrier for correction of periodontal defects in baboons: a clinical and histologic study. ( Brand, JW; Holt, RA; Jones, FL; Nordquist, RE; Vernino, AR, 1995)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (67.86)18.2507
2000's8 (28.57)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oortgiesen, DA1
Meijer, GJ1
Bronckers, AL1
Walboomers, XF1
Jansen, JA1
Murphy, KG1
Gunsolley, JC1
Cetiner, D1
Unsal, B1
Parlar, A1
Gültekin, E1
Kurtiş, B1
Bremm, LL1
Sallum, AW1
Casati, MZ1
Nociti, FH1
Sallum, EA1
Giusto, TJ1
Takahashi, D1
Odajima, T1
Morita, M1
Kawanami, M1
Kato, H1
Belal, MH1
Al-Noamany, FA1
El-Tonsy, MM1
El-Guindy, HM1
Ishikawa, I1
Hugoson, A1
Ravald, N1
Fornell, J1
Johard, G1
Teiwik, A2
Gottlow, J3
Lundgren, D1
Laurell, L2
Rylander, H1
Mathisen, T1
Nyman, S1
Rask, M1
Polson, AM5
Southard, GL4
Dunn, RL4
Polson, AP3
Billen, JR1
Laster, LL1
Vernino, AR3
Jones, FL1
Holt, RA1
Nordquist, RE1
Brand, JW1
Genon, P1
Becker, W1
Becker, BE1
Mellonig, J1
Caffesse, RG3
Warrer, K1
Caton, JG2
Reid, T1
Hürzeler, MB1
Quiñones, CR1
Schüpbach, P1
Morrison, EC1
Bogle, G2
Garrett, S3
Stoller, NH3
Swanbom, DD2
Fulfs, JC2
Rodgers, PW2
Whitman, S1
Harris, RJ1
Bouchard, P1
Giovannoli, JL1
Mattout, C1
Davarpanah, M1
Etienne, D1
Drisko, CL1
Harrold, CQ1
Greenwell, H1
Lowenguth, RA1
Duke, SP1
DeRouen, TA1
Trejo, PM1
Weltman, R1
Yewey, GL1
Evans, GH1
Yukna, RA1
Cambre, KM1
Gardiner, DL1
De Leonardis, D1
Garg, AK1
Pedrazzoli, V1
Pecora, GE1
Ringeisen, TA2
Wang, HL2
Derhalli, M2
Rapley, J2
Nechamkin, SJ2
Brekke, J2
Karapataki, S1
Falk, H1
Hugoso, A1
Olsson, G1
Slotte, C1
Johnson, LR1
Buchmann, R1
Hasilik, A1
Heinecke, A1
Lange, DE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Injectable Beta- Tricalcium Phosphate as an Occlusive Barrier Membrane in Treatment of Grade ii Furcation Involvement (Clinical and Radiographic Study)[NCT04443972]14 participants (Actual)Interventional2018-04-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for lactic acid and Furcation Defects

ArticleYear
Guided tissue regeneration for the treatment of periodontal intrabony and furcation defects. A systematic review.
    Annals of periodontology, 2003, Volume: 8, Issue:1

    Topics: Absorbable Implants; Alveolar Bone Loss; Bone Regeneration; Bone Transplantation; Consensus; Furcati

2003
Clinical regeneration with guided tissue barriers.
    Current opinion in periodontology, 1997, Volume: 4

    Topics: Alveolar Bone Loss; Collagen; Furcation Defects; Guided Tissue Regeneration, Periodontal; Humans; La

1997

Trials

13 trials available for lactic acid and Furcation Defects

ArticleYear
Guided tissue regeneration in Class II furcation defects using a resorbable polylactic acid barrier.
    American journal of dentistry, 2004, Volume: 17, Issue:6

    Topics: Absorbable Implants; Adult; Debridement; Dental Plaque Index; Female; Furcation Defects; Gingiva; Gi

2004
Treatment of human class II furcation defects using connective tissue grafts, bioabsorbable membrane, and resorbable hydroxylapatite: a comparative study.
    Journal of the International Academy of Periodontology, 2005, Volume: 7, Issue:4

    Topics: Absorbable Implants; Adult; Biocompatible Materials; Bone Substitutes; Connective Tissue; Debridemen

2005
Treatment of class II furcation involvements in humans with bioresorbable and nonresorbable guided tissue regeneration barriers. A randomized multi-center study.
    Journal of periodontology, 1995, Volume: 66, Issue:7

    Topics: Adult; Biocompatible Materials; Biodegradation, Environmental; Dental Scaling; Female; Follow-Up Stu

1995
Initial study of guided tissue regeneration in Class II furcation defects after use of a biodegradable barrier.
    The International journal of periodontics & restorative dentistry, 1995, Volume: 15, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Biodegradation, Environmental; Feasibility Studies; Female; Furca

1995
A prospective multi-center study evaluating periodontal regeneration for Class II furcation invasions and intrabony defects after treatment with a bioabsorbable barrier membrane: 1-year results.
    Journal of periodontology, 1996, Volume: 67, Issue:7

    Topics: Adolescent; Adult; Aged; Alveolar Bone Loss; Analysis of Variance; Biodegradation, Environmental; Fo

1996
Clinical evaluation of a bioabsorbable regenerative material in mandibular class II furcation therapy.
    Journal of clinical periodontology, 1997, Volume: 24, Issue:7

    Topics: Adult; Aged; Biocompatible Materials; Biodegradation, Environmental; Dental Plaque Index; Female; Fu

1997
Comparison of a bioabsorbable GTR barrier to a non-absorbable barrier in treating human class II furcation defects. A multi-center parallel design randomized single-blind trial.
    Journal of periodontology, 1997, Volume: 68, Issue:7

    Topics: Absorption; Adult; Aged; Evaluation Studies as Topic; Female; Furcation Defects; Gingival Recession;

1997
Effects of expanded polytetrafluoroethylene and polylactic acid barriers on healthy sites.
    Journal of periodontology, 1998, Volume: 69, Issue:1

    Topics: Adult; Alveolar Bone Loss; Alveolar Process; Debridement; Epithelial Attachment; Evaluation Studies

1998
Clinical evaluation of the treatment of class II furcation involvements with bioabsorbable barriers alone or associated with demineralized freeze-dried bone allografts.
    Journal of periodontology, 1999, Volume: 70, Issue:1

    Topics: Absorbable Implants; Adult; Aged; Analysis of Variance; Bone Transplantation; Decalcification Techni

1999
Use of biodegradable polylactic acid barrier materials in the treatment of grade II periodontal furcation defects in humans--Part I: A multicenter investigative clinical study.
    The International journal of periodontics & restorative dentistry, 1998, Volume: 18, Issue:6

    Topics: Absorbable Implants; Adult; Aged; Alveolar Process; Bone Regeneration; Dental Plaque Index; Female;

1998
The use of biodegradable polylactic acid barrier materials in the treatment of grade II periodontal furcation defects in humans--Part II: A multicenter investigative surgical study.
    The International journal of periodontics & restorative dentistry, 1999, Volume: 19, Issue:1

    Topics: Absorbable Implants; Adult; Aged; Alveolar Bone Loss; Analysis of Variance; Female; Follow-Up Studie

1999
Treatment of class II furcation defects using resorbable and non-resorbable GTR barriers.
    Swedish dental journal, 1999, Volume: 23, Issue:5-6

    Topics: Absorbable Implants; Adult; Analysis of Variance; Dental Plaque Index; Female; Furcation Defects; Gu

1999
PMN responses following use of 2 biodegradable GTR membranes.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:11

    Topics: Absorbable Implants; beta-N-Acetylhexosaminidases; Chronic Disease; Dental Plaque Index; Female; Fol

2001

Other Studies

13 other studies available for lactic acid and Furcation Defects

ArticleYear
Regeneration of the periodontium using enamel matrix derivative in combination with an injectable bone cement.
    Clinical oral investigations, 2013, Volume: 17, Issue:2

    Topics: Alveolar Bone Loss; Animals; Bone Cements; Bone Regeneration; Bone Substitutes; Calcium Phosphates;

2013
Evaluation of periodontal healing in class II furcation defects following guided tissue regeneration with two different types of polylactic acid membranes.
    Chinese medical journal, 2004, Volume: 117, Issue:2

    Topics: Animals; Dogs; Furcation Defects; Guided Tissue Regeneration, Periodontal; Lactic Acid; Periodontium

2004
Bioactive glass and bioabsorbable membrane in the treatment of a maxillary class II furcation defect: case report with 6-month re-entry.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2005, Volume: 26, Issue:1

    Topics: Absorbable Implants; Adult; Biocompatible Materials; Bone Regeneration; Bone Substitutes; Ceramics;

2005
Formation and resolution of ankylosis under application of recombinant human bone morphogenetic protein-2 (rhBMP-2) to class III furcation defects in cats.
    Journal of periodontal research, 2005, Volume: 40, Issue:4

    Topics: Absorbable Implants; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Bone Regene

2005
The influence of the design of two different bioresorbable barriers on the results of guided tissue regeneration therapy. An intra-individual comparative study in the monkey.
    Journal of periodontology, 1995, Volume: 66, Issue:7

    Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Collagen; Connective Tissue; Dental

1995
Evaluation of the potential of a polylactic acid barrier for correction of periodontal defects in baboons: a clinical and histologic study.
    The International journal of periodontics & restorative dentistry, 1995, Volume: 15, Issue:1

    Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Evaluation Studies as Topic; Female; Furcation De

1995
Guided tissue regeneration using a bioresorbable matrix barrier.
    Practical periodontics and aesthetic dentistry : PPAD, 1994, Volume: 6, Issue:2

    Topics: Adult; Aged; Alveolar Bone Loss; Biodegradation, Environmental; Female; Furcation Defects; Gingival

1994
Healing patterns associated with an Atrisorb barrier in guided tissue regeneration.
    Compendium (Newtown, Pa.), 1993, Volume: 14, Issue:9

    Topics: Aged; Biodegradation, Environmental; Furcation Defects; Guided Tissue Regeneration, Periodontal; Hum

1993
Guided periodontal tissue regeneration in Class II furcation defects following treatment with a synthetic bioabsorbable barrier.
    Journal of periodontology, 1997, Volume: 68, Issue:5

    Topics: Alveolar Bone Loss; Animals; Biocompatible Materials; Biodegradation, Environmental; Bone Regenerati

1997
Periodontal regeneration in naturally occurring Class II furcation defects in beagle dogs after guided tissue regeneration with bioabsorbable barriers.
    Journal of periodontology, 1997, Volume: 68, Issue:6

    Topics: Alveolar Bone Loss; Animals; Biodegradation, Environmental; Bone Regeneration; Dental Cementum; Dogs

1997
A clinical evaluation of guided tissue regeneration with a bioabsorbable matrix membrane combined with an allograft bone graft. A series of case reports.
    Journal of periodontology, 1997, Volume: 68, Issue:6

    Topics: Adult; Aged; Alveolar Bone Loss; Anti-Bacterial Agents; Biodegradation, Environmental; Bone Deminera

1997
Periodontal healing after guided tissue regeneration with Atrisorb barriers in beagle dogs.
    The International journal of periodontics & restorative dentistry, 1995, Volume: 15, Issue:6

    Topics: Alveolar Bone Loss; Animals; Dogs; Female; Follow-Up Studies; Furcation Defects; Guided Tissue Regen

1995
Periodontal regeneration of a class II furcation defect utilizing a bioabsorbable barrier in a human. A case study with histology.
    Journal of periodontology, 2001, Volume: 72, Issue:2

    Topics: Absorbable Implants; Adult; Alveolar Process; Dental Cementum; Female; Follow-Up Studies; Furcation

2001