povidone-iodine and Furcation-Defects

The aim of this controlled clinical trial was to evaluate the effect of topically applied povidone-iodine (PVP-I) used as an adjunct to non-surgical treatment of interproximal class II furcation involvements.. Thirty-two patients presenting at least one interproximal class II furcation involvement that bled on probing with probing pocket depth (PPD) ≥ 5 mm were recruited. Patients were randomly chosen to receive either subgingival instrumentation with an ultrasonic device using PVP-I (10%) as the cooling liquid (test group) or identical treatment using distilled water as the cooling liquid (control group). The following clinical outcomes were evaluated: visible plaque index, bleeding on probing (BOP), position of the gingival margin, relative attachment level (RAL), PPD and relative horizontal attachment level (RHAL). BAPNA (N-benzoyl-L-arginine-p-nitroanilide) testing was used to analyze trypsin-like activity in dental biofilm. All parameters were evaluated at baseline and 1, 3 and 6 months after non-surgical subgingival instrumentation.. Six months after treatment, both groups had similar means of PPD reduction, RAL and RHAL gain (p>0.05). These variables were, respectively, 2.20 ± 1.10 mm, 1.27 ± 1.02 mm and 1.33 ± 0.85 mm in the control group and 2.67 ± 1.21 mm, 1.50 ± 1.09 mm and 1.56 ± 0.93 mm in the test group. No difference was observed between groups at none of the posttreatment periods, regarding the number of sites showing clinical attachment gain ≥ 2 mm. However, at 6 months posttreatment, the test group presented fewer sites with PPD ≥ 5 mm than the control group. Also at 6 months the test group had lower BAPNA values than control group.. The use of PVP-I as an adjunct in the non-surgical treatment of interproximal class II furcation involvements provided limited additional clinical benefits.

Topics: Administration, Topical; Adult; Analysis of Variance; Anti-Infective Agents, Local; Benzoylarginine Nitroanilide; Dental Plaque Index; Female; Follow-Up Studies; Furcation Defects; Humans; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Povidone-Iodine; Time Factors; Treatment Outcome; Ultrasonic Therapy

The aim of this clinical trial was to evaluate the effect of topically applied povidone-iodine (polyvinylpyrrolidone and iodine [PVP-I]) used as an adjunct to non-surgical therapy of furcation involvements.. Forty-four patients presenting at least one Class II furcation involvement that bled on probing with probing depth (PD)>or=5 mm were recruited. Patients were stratified into two treatment groups: 1) subgingival instrumentation by an ultrasonic device using PVP-I (10%) as the cooling liquid (test); and 2) identical treatment using distilled water as the cooling liquid (control). The following clinical outcomes were evaluated: plaque index, bleeding on probing (BOP), position of the gingival margin, relative attachment level (RAL), PD, and relative horizontal attachment level (RHAL). The N-benzoyl-L-arginine-p-nitroanilide (BAPNA) test was used to analyze the trypsin-like activity in dental biofilm. The clinical and biochemical parameters were evaluated at baseline and 1, 3, and 6 months after therapy.. Both groups had similar means of PD reduction and RAL and RHAL gain. At 6 months, these variables were, respectively, 2.31, 1.17, and 1.00 mm in the control group and 2.31, 1.23, and 1.02 mm in the test group. There was also no difference between groups regarding the number of furcation sites presenting RAL gain>or=2 mm. The results of the BAPNA test failed to demonstrate significant differences between groups.. Non-surgical therapy can effectively treat Class II furcation involvements, and the use of topically applied PVP-I as an adjunct to subgingival instrumentation does not provide additional benefits.

Topics: Administration, Topical; Adult; Anti-Infective Agents, Local; Benzoylarginine Nitroanilide; Biofilms; Chromogenic Compounds; Dental Plaque Index; Female; Follow-Up Studies; Furcation Defects; Gingival Hemorrhage; Gingival Recession; Humans; Male; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Povidone-Iodine; Single-Blind Method; Subgingival Curettage; Treatment Outcome; Ultrasonic Therapy

This investigation compared a traditional periodontal surgical method with a non-surgical treatment of scaling and root planing by an ultrasonic device (Odontoson M) using irrigation with an iodised solution. 8 adult patients with periodontal disease were each treated at 2 randomly chosen quadrants by a Widman flap type surgical technique, and the remaining non-surgically. The patients then attended bi-monthly oral hygiene sessions over a period of 1 year. At that stage, clinical evaluation revealed that the Odontoson M plus an ionized irrigant solution achieved a statistically comparable outcome to that of surgical treatment, even in the pockets initially up to 7 mm in depth.

Topics: Adult; Dental Plaque Index; Dental Scaling; Female; Furcation Defects; Humans; Male; Middle Aged; Periodontal Index; Periodontal Pocket; Povidone-Iodine; Root Planing; Subgingival Curettage; Therapeutic Irrigation; Treatment Outcome; Ultrasonic Therapy

Kostmann syndrome is a rare, congenital immunological disorder caused by a mutation of the hematopoietic cell-specific LYN substrate 1-associated protein X1. These patients pose a unique challenge to the dental practitioner due to the severe oral infections that are often seen in this population. The patient described in this report is a 16-year-old female with Kostmann syndrome-associated periodontitis. The treatment consisted of scaling and root planing performed in conjunction with subgingival irrigation with povidone-iodine solution. This report details how Kostmann syndrome-associated periodontitis can be successfully treated and maintained long-term, using non-surgical treatment modalities and local antimicrobial therapy.

Topics: Adolescent; Anti-Infective Agents, Local; Congenital Bone Marrow Failure Syndromes; Dental Scaling; Female; Follow-Up Studies; Furcation Defects; Gingival Recession; Gingivitis; Humans; Neutropenia; Periodontal Debridement; Periodontal Pocket; Periodontitis; Povidone-Iodine; Root Planing; Therapeutic Irrigation